Open access peer-reviewed Edited Volume

Understanding Tuberculosis

Deciphering the Secret Life of the Bacilli

Mycobacterium tuberculosis, as recent investigations demonstrate, has a complex signaling expression, which allows its close interaction with the environment and one of its most renowned properties: the ability to persist for long periods of time under a non-replicative status. Although this skill is well characterized in other bacteria, the intrinsically very slow growth rate of Mycobium tuberculosis, together with a very thick and complex cell wall, makes this pathogen specially adapted to the stress that could be generated by the host against them. In this book, different aspects of these properties are displayed by specialists in the field.

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Understanding TuberculosisDeciphering the Secret Life of the BacilliEdited by Pere-Joan Cardona

Published: February 17th 2012

DOI: 10.5772/2479

ISBN: 978-953-307-946-2

eBook (PDF) ISBN: 978-953-51-4355-0

Copyright year: 2012

Books open for chapter submissions

57044 Total Chapter Downloads

9 Crossref Citations

43 Web of Science Citations

61 Dimensions Citations


Open access peer-reviewed

1. Molecular Biomarkers for Ancient Tuberculosis

By David E. Minnikin, Oona Y-C. Lee, Houdini H.T. Wu, Gurdyal S. Besra and Helen D. Donoghue


Open access peer-reviewed

2. Genomic Variability of Mycobacterium tuberculosis

By María Mercedes Zambrano, Ginna Hernández-Neuta, Iván Hernández-Neuta, Andrea Sandoval, Andrés Cubillos-Ruiz, Alejandro Reyes and Patricia Del Portillo


Open access peer-reviewed

3. IS6110 the Double-Edged Passenger

By María del Carmen Menéndez, Sofía Samper, Isabel Otal and María Jesús García


Open access peer-reviewed

4. Response of Mycobacterial Species to an Acidic Environment

By Beatrice Saviola


Open access peer-reviewed

5. Mycobacterium Tuberculosis Signaling via c-AMP

By Mario Alberto Flores-Valdez, Jeannette Barba and Angel H. Alvarez


Open access peer-reviewed

6. Mycobacterium tuberculosis RD-1 Secreted Antigens as Protective and Risk Factors for Tuberculosis

By Niladri Ganguly and Pawan Sharma


Open access peer-reviewed

7. Mycobacterium tuberculosis Transcriptome In Vivo Studies – A Key to Understand the Pathogen Adaptation Mechanism

By Tatyana Azhikina and Timofey Skvortsov


Open access peer-reviewed

8. Morphological Characterization of Mycobacterium tuberculosis

By Ali Akbar Velayati and Parissa Farnia


Open access peer-reviewed

9. Mycobacterial Strains of Different Virulence Trigger Dissimilar Patterns of Immune System Activation In Vivo

By Aaron Silva-Sanchez, Selene Meza-Pérez, Fernando Muñoz-Teneria, Dulce Mata, Juana Calderon-Amador, Sergio Estrada-Parra, Rogelio Hernández-Pando, Iris Estrada-García and Leopoldo Flores-Romo


Open access peer-reviewed

10. Biofilms of Mycobacterium tuberculosis: New Perspectives of an Old Pathogen

By Anil K. Ojha and Graham F. Hatfull


Open access peer-reviewed

11. Cell Wall Deficiency in Mycobacteria: Latency and Persistence

By Nadya Markova


Open access peer-reviewed

12. Mycobacterium tuberculosis: Dormancy, Persistence and Survival in the Light of Protein Synthesis

By Ranjeet Kumar and Suparna Sanyal


Open access peer-reviewed

13. Lipid Surrounding of Mycobacteria: Lethal and Resuscitating Effects

By Alla A. Selishcheva, Galina M. Sorokoumova and Evgeniya V. Nazarova


Open access peer-reviewed

14. Heat Shock Proteins in Mycobacterium tuberculosis: Involvement in Survival and Virulence of the Pathogen

By Divya Bajaj and Janendra K. Batra


Open access peer-reviewed

15. Mammalian Heme Peroxidases and Mycobacterium tuberculosis

By Amit K. Singh, Nisha Pandey, Mau Sinha, Sujata Sharma and Tej P. Singh


Open access peer-reviewed

16. Thiol-Dependent Peroxidases in Mycobacterium tuberculosis Antioxidant Defense

By Martín Hugo, Rafael Radi and Madia Trujillo


Open access peer-reviewed

17. Characteristic Conformational Behaviors of Representative Mycolic Acids in the Interfacial Monolayer

By Masumi Villeneuve


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI
  • BIOSIS Previews

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