Open access peer-reviewed Edited Volume

Understanding Tuberculosis

Analyzing the Origin of Mycobacterium Tuberculosis Pathogenicity

Mycobacterium tuberculosis in an attempt to understand the extent to which the bacilli has adapted itself to the host and to its final target. On the other hand, there is a section in which other specialists discuss how to manipulate this immune response to obtain innovative prophylactic and therapeutic approaches to truncate the intimal co-evolution between Mycobacterium tuberculosis and the Homo sapiens.

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Understanding TuberculosisAnalyzing the Origin of Mycobacterium Tuberculosis PathogenicityEdited by Pere-Joan Cardona

Published: February 24th 2012

DOI: 10.5772/2478

ISBN: 978-953-307-942-4

eBook (PDF) ISBN: 978-953-51-4348-2

Copyright year: 2012

Books open for chapter submissions

68636 Total Chapter Downloads

28 Crossref Citations

51 Web of Science Citations

81 Dimensions Citations


Open access peer-reviewed

1. Ten Questions to Challenge the Natural History of Tuberculosis

By Pere-Joan Cardona


Open access peer-reviewed

2. Inflammation and Immunopathogenesis of Tuberculosis Progression

By Irina Lyadova


Open access peer-reviewed

3. Host–Pathogen Interactions in Tuberculosis

By Clara Espitia, Eden Rodríguez, Lucero Ramón-Luing, Gabriela Echeverría-Valencia and Antonio J. Vallecillo


Open access peer-reviewed

4. Broadening Our View About the Role of Mycobacterium tuberculosis Cell Envelope Components During Infection: A Battle for Survival

By Jordi B. Torrelles


Open access peer-reviewed

5. For Host Factors Weddings and a Koch’s Bacillus Funeral: Actin, Lipids, Phagosome Maturation and Inflammasome Activation

By Elsa Anes


Open access peer-reviewed

6. The Role of Non-Phagocytic Cells in Mycobacterial Infections

By B.E. Garcia-Perez, N.S. Castrejon-Jimenez and J. Luna-Herrera


Open access peer-reviewed

7. Epithelioid Cell: A New Opinion on Its Nature, Parentage, Histogenesis, Cytomorphogenesis, Morphofunctional Potency, Role in Pathogenesis and Morphogenesis of Tuberculous Process

By Sergey Arkhipov


Open access peer-reviewed

8. How Mycobacterium tuberculosis Manipulates Innate and Adaptive Immunity – New Views of an Old Topic

By Susanna Brighenti and Maria Lerm


Open access peer-reviewed

9. Role of TNF in Host Resistance to Tuberculosis Infection: Membrane TNF Is Sufficient to Control Acute Infection

By Valerie Quesniaux, Irene Garcia, Muazzam Jacobs and Bernhard Ryffel


Open access peer-reviewed

10. Immunoregulatory Role of GM-CSF in Pulmonary Tuberculosis

By Zissis C. Chroneos and Chinnaswamy Jagannath


Open access peer-reviewed

11. Double Edge Sword: The Role of Neutrophils in Tuberculosis

By Patricia González-Cano, Rommel Chacón-Salinas, Victoria Ramos-Kichik, Rogelio Hernández-Pando, Jeanet Serafín-López, Georgina Filio-Rodríguez, Sergio Estrada-Parra and Iris Estrada-García


Open access peer-reviewed

12. Role of NK Cells in Tuberculous Pleurisy as Innate Promoters of Local Type 1 Immunity with Potential Application on Differential Diagnosis

By Pablo Schierloh, Silvia De La Barrera and Maria Sasiain


Open access peer-reviewed

13. Are Polyfunctional Cells Protective in M. tuberculosis Infection?

By Nadia Caccamo and Francesco Dieli


Open access peer-reviewed

14. MHC Polymorphism and Tuberculosis Disease

By Khalid Sadki, Youssef Bakri, M'Hamed Tijane and Saaid Amzazi


Open access peer-reviewed

15. Partial Mapping of the IL-10 Promoter Region: Identification of New SNPs and Association with Tuberculosis Outcome in Brazilians

By L.B. Spinassé, M.Q.P. Lopes, A.B. Miranda, R.L.F. Teixeira, F.C.Q. Mello, J.R. Lapa e Silva, P.N. Suffys and A.R. Santos


Open access peer-reviewed

16. Vaccines Against Mycobacterium tuberculosis: An Overview from Preclinical Animal Studies to the Clinic

By Rhea N. Coler, Susan L. Baldwin, and Steven G. Reed


Open access peer-reviewed

17. Immune Responses Against Mycobacterium

By Toshi Nagata and Yukio Koide


Open access peer-reviewed

18. Towards a New Challenge in TB Control: Development of Antibody-Based Protection

By Armando Acosta, Yamile Lopez, Norazmi Mohd Nor, Rogelio Hernández Pando, Nadine Alvarez and Maria Elena Sarmiento


Open access peer-reviewed

19. Identification of CD8+ T Cell Epitopes Against Mycobacterium tuberculosis

By Fei Chen, Yanfeng Gao and Yuanming Qi


Open access peer-reviewed

20. The Hidden History of Tuberculin

By Cristina Vilaplana and Pere-Joan Cardona


Open access peer-reviewed

21. Immunotherapy of Tuberculosis with IgA and Cytokines

By Rajko Reljic and Juraj Ivanyi


Open access peer-reviewed

22. Therapy for Tuberculosis: M. vaccae Inclusion into Routine Treatment

By Diana G. Dlugovitzky, Cynthia Stanford and John Stanford


Open access peer-reviewed

23. Adjuvant Interferon Gamma in the Management of Multidrug - Resistant Tuberculosis

By Idrian García-García, María T Milanés-Virelles, Pedro A López-Saura, Roberto Suárez-Méndez, Magalys Valdés-Quintana, Norma Fernández-Olivera, Carmen M Valenzuela-Silva, Lidia González- Méndez, Yamilet Santos-Herrera, Gladys Abreu-Suárez and Isis Cayón-Escobar


Open access peer-reviewed

24. Biochemical and Immunological Characterization of the Mycobacterium tuberculosis 28 kD Protein

By Elinos-Báez Carmen Martha and Ramírez González


Open access peer-reviewed

25. P27-PPE36 (Rv2108) Mycobacterium tuberculosis Antigen – Member of PPE Protein Family with Surface Localization and Immunological Activities

By Vincent Le Moigne and Wahib Mahana


Edited Volume and chapters are indexed in

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  • CNKI
  • BKCI
  • BIOSIS Previews

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