Open access peer-reviewed Edited Volume

Understanding Tuberculosis

Global Experiences and Innovative Approaches to the Diagnosis

Mycobacterium tuberculosis is a disease that is transmitted through aerosol. This is the reason why it is estimated that a third of humankind is already infected by Mycobacterium tuberculosis. The vast majority of the infected do not know about their status. Mycobacterium tuberculosis is a silent pathogen, causing no symptomatology at all during the infection. In addition, infected people cannot cause further infections. Unfortunately, an estimated 10 per cent of the infected population has the probability to develop the disease, making it very difficult to eradicate. Once in this stage, the bacilli can be transmitted to other persons and the development of clinical symptoms is very progressive. Therefore the diagnosis, especially the discrimination between infection and disease, is a real challenge. In this book, we present the experience of worldwide specialists on the diagnosis, along with its lights and shadows.

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Understanding TuberculosisGlobal Experiences and Innovative Approaches to the DiagnosisEdited by Pere-Joan Cardona

Published: February 15th 2012

DOI: 10.5772/1483

ISBN: 978-953-307-938-7

eBook (PDF) ISBN: 978-953-51-4360-4

Copyright year: 2012

Books open for chapter submissions

113471 Total Chapter Downloads

30 Crossref Citations

54 Web of Science Citations

78 Dimensions Citations


Open access peer-reviewed

1. Clinical Laboratory Diagnostics for Mycobacterium tuberculosis

By N. Esther Babady and Nancy L. Wengenack


Open access peer-reviewed

2. Laboratory Diagnosis of Latent and Active Tuberculosis Infections in Trinidad & Tobago and Determination of Drug Susceptibility Profile of Tuberculosis Isolates in the Caribbean

By Patrick Eberechi Akpaka and Shirematee Baboolal


Open access peer-reviewed

3. Tuberculosis is Still a Major Challenge in Africa

By Simeon I.B. Cadmus, Osman El Tayeb and Dick van Soolingen


Open access peer-reviewed

4. Tuberculosis in Saudi Arabia

By Sahal Al-Hajoj


Open access peer-reviewed

5. Diagnosis of Mycobacterium tuberculosis

By Faten Al-Zamel


Open access peer-reviewed

6. Diagnosis of Smear-Negative Pulmonary Tuberculosis in Low-Income Countries: Current Evidence in Sub-Saharan Africa with Special Focus on HIV Infection or AIDS

By Claude Mambo Muvunyi and Florence Masaisa


Open access peer-reviewed

7. Immunologic Diagnosis of Neurotuberculosis

By Iacob Simona Alexandra, Banica Dorina, Iacob Diana Gabriela, Panaitescu Eugenia, Radu Irina and Cojocaru Manole


Open access peer-reviewed

8. Diagnostic Methods for Mycobacterium tuberculosis and Challenges in Its Detection in India

By Shamsher S. Kanwar


Open access peer-reviewed

9. Management of TB in HIV Subjects, the Experience in Thailand

By Attapon Cheepsattayakorn


Open access peer-reviewed

10. Mycobacterium tuberculosis: Biorisk, Biosafety and Biocontainment

By Wellman Ribón


Open access peer-reviewed

11. New Diagnostics for Mycobacterium tuberculosis

By Michaela Lucas, Andrew Lucas and Silvana Gaudieri


Open access peer-reviewed

12. Nanodiagnostics for Tuberculosis

By Bruno Veigas, Gonçalo Doria and Pedro V. Baptista


Open access peer-reviewed

13. Sputum Smear Microscopy for Tuberculosis: Evaluation of Autofocus Functions and Automatic Identification of Tuberculosis Mycobacterium

By Cicero F. F. Costa Filho and Marly G. F. Costa


Open access peer-reviewed

14. The Use of Phage for Detection, Antibiotic Sensitivity Testing and Enumeration

By Catherine Rees and George Botsaris


Open access peer-reviewed

15. Molecular Imaging in TB: From the Bench to the Clinic

By Nuria Andreu, Paul T. Elkington and Siouxsie Wiles


Open access peer-reviewed

16. Data Mining Techniques in the Diagnosis of Tuberculosis

By T. Asha, S. Natarajan and K. N. B. Murthy


Open access peer-reviewed

17. Immunological Diagnosis of Active and Latent TB

By Beata Shiratori, Hiroki Saitoh, Umme Ruman Siddiqi, Jingge Zhao, Haorile Chagan-Yasutan, Motoki Usuzawa, Chie Nakajima, Yasuhiko Suzuki and Toshio Hattori


Open access peer-reviewed

18. Immune Diagnosis of Tuberculosis Through Novel Technologies

By Miguel A. Arroyo-Ornelas, Ma. Concepción Arenas-Arrocena, Horacio V. Estrada, Victor M. Castaño and Luz M. López-Marín


Open access peer-reviewed

19. Exosomes: New Tuberculosis Biomarkers – Prospects From the Bench to the Clinic

By Nicole A. Kruh-Garcia, Jeff S. Schorey and Karen M. Dobos


Open access peer-reviewed

20. Molecular Techniques for Identification of Species of the Mycobacterium tuberculosis Complex: The use of Multiplex PCR and an Adapted HPLC Method for Identification of Mycobacterium bovis and Diagnosis of Bovine Tuberculosis

By Eduardo Eustáquio de Souza Figueiredo, Carlos Adam Conte Júnior, Leone Vinícius Furlanetto, Flávia Galindo Silvestre Silva, Rafael Silva Duarte, Joab Trajano Silva, Walter Lilenbaum and Vânia Margaret Flosi Paschoalin


Open access peer-reviewed

21. Survey and Molecular Characterization of Drug- Resistant M. tuberculosis Clinical Isolates from Zunyi, Guizhou Province of China

By Ling Chen, Hong Zhang, Jian-Yong Zhang, Na-Na Li, Mei Liu, Zhao-Jing Zong, Jian-Hua Wang and Sheng-Lan Wang


Open access peer-reviewed

22. Molecular Biological Techniques for Detection of Multidrug Resistant Tuberculosis (MDR) and Extremely Drug Resistant Tuberculosis (XDR) in Clinical Isolates of Mycobacterium tuberculosis

By K.L. Therese, R. Gayathri and H.N. Madhavan


Open access peer-reviewed

23. Detection of Mycobacterium tuberculosis and Drug Resistance: Opportunies and Challenges in Morocco

By I. Chaoui1, M. Abid, My. El Messaoudi and My. D. El Mzibri


Open access peer-reviewed

24. Pattern of Circulating Mycobacterium tuberculosis Strains in Sri Lanka

By Dhammika Magana-Arachchi


Open access peer-reviewed

25. Health Interventions to Improve the Medication Efficacy in Tuberculosis Treatment

By Jean Leandro dos Santos, Chung Man Chin, Ednir de Oliveira Vizioli, Fernando Rogério Pavan and Luiz Antonio Dutra


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI
  • BIOSIS Previews

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