Open access peer-reviewed Edited Volume

Diabetic Nephropathy

Edited by John Chan

University of Montreal, Canada

Internationally renowned experts have provided data on their own studies, and discuss the relative usefulness of their work in relation to diabetic nephropathy. The first section describes the novel role of intrarenal renin-angiotensin-aldosterone system (RAAS) and oxidative stress in the development of diabetic nephropathy and discusses the current and novel pharmacological interventions in the treatment of diabetic nephropathy. The second section discusses other important contributors outside of the RAAS in the pathogenesis of diabetic nephropathy including AGE/RAGE, epithelial-mesenchymal-transition (EMT) and immune cytokines. Features: Provides novel information on various pathophysiological determinants in the development of diabetic nephropathy Provides novel information on various pharmacological interventions of diabetic nephropathy

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Diabetic NephropathyEdited by John Chan

Published: April 20th 2012

DOI: 10.5772/1889

ISBN: 978-953-51-0543-5

eBook (PDF) ISBN: 978-953-51-6978-9

Copyright year: 2012

Books open for chapter submissions

19669 Total Chapter Downloads

9 Crossref Citations

14 Web of Science Citations

14 Dimensions Citations


Open access peer-reviewed

1. Up-Regulation of Renin-Angiotensin System in Diabetes and Hypertension: Implications on the Development of Diabetic Nephropathy

By Dulce Elena Casarini, Danielle Yuri Arita, Tatiana Sousa Cunha, Fernanda Aparecida Ronchi, Danielle Sanches Aragão, Rodolfo Mattar Rosa, Nadia Sousa Cunha Bertoncello and Fernanda Klein Marcondes


Open access peer-reviewed

2. Renal Angiotensinogen Gene Expression and Tubular Atrophy in Diabetic Nephropathy

By Brice E. T. Nouthe, Maya Saleh, Shao-Ling Zhang and John S. D. Chan


Open access peer-reviewed

3. Diabetic Nephropathy: Role of Aldosterone and Benefits of Therapy with Aldosterone Receptor Blocker

By Jayson Yap and Mohammad G. Saklayen


Open access peer-reviewed

4. Drug and Diabetic Nephropathy

By Rozina Rani


Open access peer-reviewed

5. Kidney ADP-Ribosyl Cyclase Inhibitors as a Therapeutic Tool for Diabetic Nephropathy

By Uh-Hyun Kim


Open access peer-reviewed

6. Significance of Advanced Glycation End-Products (AGE) and the Receptor for AGE (RAGE) in Diabetic Nephropathy

By Tarek Kamal, Yasuhiko Yamamoto and Hiroshi Yamamoto


Open access peer-reviewed

7. The Contribution of Fibronectin ED-A Expression to Myofibroblast Transdifferentiation in Diabetic Renal Fibrosis

By Keisuke Ina, Hirokazu Kitamura, Shuji Tatsukawa and Yoshihisa Fujikura


Open access peer-reviewed

8. Immunoinflammation in Diabetic Nephropathy: Molecular Mechanisms and Therapeutic Options

By Virginia Lopez-Parra, Beñat Mallavia, Jesus Egido and Carmen Gomez-Guerrero


Open access peer-reviewed

9. Study of Diabetic Hypertensive Nephropathy in the Local Population of Pakistan

By Samreen Riaz and Saadia Shahzad Alam


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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