Open access peer-reviewed Edited Volume

Liver Regeneration

Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration.

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Liver RegenerationEdited by Pedro Baptista

Published: May 16th 2012

DOI: 10.5772/1645

ISBN: 978-953-51-0622-7

eBook (PDF) ISBN: 978-953-51-7000-6

Copyright year: 2012

Books open for chapter submissions

29302 Total Chapter Downloads

2 Crossref Citations

9 Web of Science Citations

13 Dimensions Citations


Open access peer-reviewed

1. Hepatocytes and Progenitor - Stem Cells in Regeneration and Therapy

By Laura Amicone, Franca Citarella, Marco Tripodi and Carla Cicchini


Open access peer-reviewed

2. Liver Progenitor Cells, Cancer Stem Cells and Hepatocellular Carcinoma

By Janina E.E. Tirnitz-Parker, George C.T. Yeoh and John K. Olynyk


Open access peer-reviewed

3. Hepatic Progenitors of the Liver and Extra-Hepatic Tissues

By Eva Schmelzer


Open access peer-reviewed

4. Possible Roles of Nuclear Lipids in Liver Regeneration

By M. Viola-Magni and P.B. Gahan


Open access peer-reviewed

5. Matrix Restructuring During Liver Regeneration is Regulated by Glycosylation of the Matrix Glycoprotein Vitronectin

By Haruko Ogawa, Kotone Sano, Naomi Sobukawa and Kimie Asanuma-Date


Open access peer-reviewed

6. The Protective Effect of Antioxidants in Alcohol Liver Damage

By José A. Morales González, Liliana Barajas-Esparza, Carmen Valadez-Vega, Eduardo Madrigal-Santillán, Jaime Esquivel-Soto, Cesar Esquivel-Chirino, Ana María Téllez-López, Maricela López-Orozco and Clara Zúñiga-Pérez


Open access peer-reviewed

7. Analbuminemic Rat Model for Hepatocyte Transplantation

By Katsuhiro Ogawa and Mitsuhiro Inagaki


Open access peer-reviewed

8. Rodent Models with Humanized Liver: A Tool to Study Human Pathogens

By Ivan Quétier, Nicolas Brezillon and Dina Kremsdorf


Open access peer-reviewed

9. Liver Parenchyma Regeneration in Connection with Extended Surgical Procedure - Experiment on Large Animal

By Vaclav Liska, Vladislav Treska, Hynek Mirka, Ondrej Vycital, Jan Bruha, Pavel Pitule, Jana Kopalova, Tomas Skalicky, Alan Sutnar, Jan Benes, Jiri Kobr, Alena Chlumska, Jaroslav Racek and Ladislav Trefil


Open access peer-reviewed

10. Liver Transplantation in the Clinic - Progress Made During the Last Three Decades

By Marco Carbone,Giuseppe Orlando, Brian Sanders, Christopher Booth, Tom Soker, Quirino Lai, Katia Clemente, Antonio Famulari, Jan P. Lerut and Francesco Pisani


Open access peer-reviewed

11. Potential of Mesenchymal Stem Cells for Liver Regeneration

By Melisa Andrea Soland, Christopher D. Porada and Graça D. Almeida-Porada


Open access peer-reviewed

12. Cell Based Therapy for Chronic Liver Disease: Role of Fetal Liver Cells in Restoration of the Liver Cell Functions

By Chaturvedula Tripura, Aleem Khan and Gopal Pande


Open access peer-reviewed

13. Liver Regeneration and Bioengineering - The Emergence of Whole Organ Scaffolds

By Pedro M. Baptista, Dipen Vyas and Shay Soker


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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