Open access peer-reviewed Edited Volume

Leishmaniasis - General Aspects of a Stigmatized Disease

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Academic Editor

Leonardo de Azevedo Calderon

Oswaldo Cruz Foundation

PublishedApril 13th, 2022

Doi10.5772/intechopen.95200

ISBN978-1-83968-082-3

Print ISBN978-1-83968-081-6

eBook (PDF) ISBN978-1-83968-092-2

Copyright year2022

Number of pages256

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Table of Contents

Open access peer-reviewed  chapters

1. Leishmaniasis: Molecular Aspects of Parasite Dimorphic Forms Life Cycle

By Natanael Endrew Souto Maior Torres Bonfim, Ana Lígia Barbour Scott and Leonardo de Azevedo Calderon

62
2. Protective and Pathogenic Immune Responses to Cutaneous Leishmaniasis

By Elina Panahi, Danielle I. Stanisic, Christopher S. Peacock and Lara J. Herrero

76
3. Extracellular Vesicles Released by Leishmania: Impact on Disease Development and Immune System Cells

By Rogéria Cristina Zauli, Andrey Sladkevicius Vidal, Talita Vieira Dupin, Aline Correia Costa de Morais, Wagner Luiz Batista and Patricia Xander

126
4. Treatment of Leishmaniasis

By R. Sivayogana, Aishwarya Krishnakumar, S. Kumaravel, Rajesh Rajagopal and P. Ravikanth

47
5. Visceral Leishmaniasis: Asymptomatic Facts

By Medhavi Sudarshan and Sumit Sharan

120
8. Use of Cell Biology to Identify Cellular Targets in Drug Development Process against Leishmania Sp.

By Gabrielle dos Santos da Silva e Miranda, Joseane Lima Prado Godinho, Sara Teixeira de Macedo-Silva, Brunno Renato Farias Verçoza, Alisson Amaral da Rocha, Milena Barenco Pires de Abreu Sodré, Victor Feliciano dos Santos Ramos and Juliany Cola Fernandes Rodrigues

129
106
10. microRNAs: Are They Important in the Development of Resistance in Leishmaniasis?

By Sandra Alves de Araújo, Tatiane Aranha da Penha-Silva, Jaqueline Diniz Pinho, Marcelo de Souza Andrade and Ana Lucia Abreu-Silva

172
11. Molecular Informatics of Trypanothione Reductase of Leishmania major Reveals Novel Chromen-2-One Analogues as Potential Leishmanicides

By Samuel K. Kwofie, Gabriel B. Kwarko, Emmanuel Broni, Michael B. Adinortey and Michael D. Wilson

132
12. Plant-Based Alternative Treatment for Leishmaniasis: A Neglected Tropical Disease

By Nargis Shaheen, Chaitenya Verma and Naveeda Akhter Qureshi

23

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