Open access peer-reviewed Edited Volume

Muscle Cell and Tissue

Novel Molecular Targets and Current Advances

Edited by Kunihiro Sakuma

Tokyo Institute of Technology

The loss of skeletal muscle mass and strength substantially impairs physical performance and quality of life. This book details some approaches to the treatment of muscle wasting. It also reviews novel applications against pulmonary arterial hypertension such as cell reprogramming and the use of anticancer drugs that induce programmed cell death. Vascular smooth muscle cells (VSMCs) are the most prevalent cell types in blood vessels and serve critical regulatory roles. This publication also introduces mathematical models concerning the molecular mechanism and targets of cyclic guanosine 3′,5′-monophosphate (cGMP) in the contraction of VSMCs. This book will be of interest to professionals in clinical practice, medical and health care students, and researchers working in muscle-related fields of science.

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Muscle Cell and TissueNovel Molecular Targets and Current AdvancesEdited by Kunihiro Sakuma

Published: July 7th 2021

DOI: 10.5772/intechopen.91539

ISBN: 978-1-83968-651-1

Print ISBN: 978-1-83968-650-4

eBook (PDF) ISBN: 978-1-83968-652-8

Copyright year: 2021

Books open for chapter submissions

576 Total Chapter Downloads


Open access peer-reviewed

1. Exercise Therapy for Patients with Heart Failure: Focusing on the Pathophysiology of Skeletal Muscle

By Nobuo Morotomi, Kunihiro Sakuma and Kotomi Sakai


Open access peer-reviewed

2. Evidence for the Role of Cell Reprogramming in Naturally Occurring Cardiac Repair

By Nataliia V. Shults and Yuichiro J. Suzuki


Open access peer-reviewed

3. Interventional Strategies to Delay Aging-Related Dysfunctions of the Musculoskeletal System

By Naomasa Fukase, Ingrid K. Stake, Yoichi Murata, William S. Hambright, Sudheer Ravuri, Marc J. Philippon and Johnny Huard


Open access peer-reviewed

4. Strategies to Treat Pulmonary Hypertension Using Programmed Cell Death-Inducing Anti-Cancer Drugs without Damaging the Heart

By Yuichiro J. Suzuki, Yasmine F. Ibrahim, Vladyslava Rybka, Jaquantey R. Bowens, Adenike S. Falade and Nataliia V. Shults


Open access peer-reviewed

5. Hypothenar Muscles and Guyon’s Canal

By Georgi P. Georgiev


Open access peer-reviewed

6. Molecular Mechanisms and Targets of Cyclic Guanosine Monophosphate (cGMP) in Vascular Smooth Muscles

By Aleš Fajmut


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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