Open access peer-reviewed Edited Volume

Muscular Dystrophies

Edited by Kunihiro Sakuma

Tokyo Institute of Technology

Skeletal muscle is a highly plastic organ that is modulated by various pathways controlling protein turnover. Muscle loss is common in muscular dystrophy, in which marked loss of various proteins such as the dystrophin-glycoprotein complex occurs around muscle fibers. This book provides a comprehensive overview of the various muscular dystrophies, including characteristics, diagnosis, and classification. General treatment of drugs (e.g. corticosteroids) and physical therapy for muscular dystrophies are discussed. In addition, current applications for cell and tissue engineering using muscle stem cells or gene therapy are introduced. This book also deals with the recent advances in appropriate models of drug screening using cell cultures or mammalian organs in vitro in this field.

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Muscular DystrophiesEdited by Kunihiro Sakuma

Published: October 2nd 2019

DOI: 10.5772/intechopen.73974

ISBN: 978-1-78923-846-4

Print ISBN: 978-1-78923-845-7

eBook (PDF) ISBN: 978-1-83962-224-3

Copyright year: 2019

Books open for chapter submissions

4778 Total Chapter Downloads

3 Crossref Citations

3 Web of Science Citations

8 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Muscular Dystrophy and Recent Therapeutic Strategy

By Kunihiro Sakuma


Open access peer-reviewed

2. Clinical and Molecular Diagnosis in Muscular Dystrophies

By Gisela Gaina, Magdalena Budisteanu, Emilia Manole and Elena Ionica


Open access peer-reviewed

3. Cognitive Function and Quality of Life of Muscular Dystrophy

By Yukihiko Ueda


Open access peer-reviewed

4. Electrophysiological Assessment of CNS Abnormalities in Muscular Dystrophy

By Stefan M. Golaszewski and Raffaele Nardone


Open access peer-reviewed

5. Ocular Pathology of Fukuyama Congenital Muscular Dystrophy

By Tomoko Yamamoto, Yoichiro Kato and Noriyuki Shibata


Open access peer-reviewed

6. Physical Exercise as a Tool to Delay the Development Process of Duchenne Muscular Dystrophy

By Samuel Alexandre Almeida Honório, Marco Batista, Jorge Santos, João Petrica, Helena Mesquita, João Serrano, Jaime Ribeiro and Júlio Martins


Open access peer-reviewed

7. Pharmacological Actions and Potential Therapeutic Use of Cannabinoids in Duchenne’s Muscular Dystrophy

By Fabio Arturo Iannotti


Open access peer-reviewed

8. Interspecies Translation: Bovine Marbling to Human Muscular Dystrophy

By Jose L. Valenzuela, Sally S. Lloyd, Edward J. Steele, Francis L. Mastaglia and Roger L. Dawkins


Edited Volume and chapters are indexed in

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  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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