\r\n\tRNA therapies evolved as profitable and widely applicable individualized treatment solutions. Moreover, RNA-based therapeutic vaccines (e.g., against SARS-CoV-2 infection) have been proven to be safe and effective, and several of them are approved by the United States Food and Drug Administration (FDA).
\r\n\tThis book aims to present distinct classes of RNA therapeutics, ranging from single-stranded antisense oligonucleotides (ASOs), and subclasses of RNA interferences (miRNAs and other RNAi), to in vitro transcribed mRNAs and RNA vaccines. Also, it will present some of the challenges in RNA drug engineering, delivery, and specificity. Additionally, the improvement of pharmacological effectiveness will be discussed. Monumental breakthroughs in molecular biology, computational chemistry, bioinformatics, and individualized genomics, which undoubtedly propelled RNA therapeutics through the commercialization stage, will also be examined in this book.
\r\n\tRNA therapeutics have had a significant impact on medicine, the economy, and overall public health; they are becoming prescription drugs, and this holds great promise for modernizing healthcare.
Intimate apparel is a kind of garment which is worn next to the skin, and thus it behaves as human’s second skin. Conventional bra, underwear, sports bra, pantyhose, swimwear, mastectomy bra as well as maternity underwear, body shaper, and corset are described as intimate apparel, and this kind of apparel is an interdisciplinary subject involving body beauty, human anatomy and anthropometrics, pattern design, textile engineering, as well as health science [1]. As intimate apparel contacts with the skin directly, its comfort characteristics are more important than that of outerwear, and from this point of view in this chapter, comfort performances of intimate apparels were discussed.
\nComfort is a complex state of mind that depends on many physical, physiological, and psychological factors [2]. Slater defined comfort as “a pleasant state of physiological, psychological and physical harmony between a human being and the environment” [3]. The impact of clothing on comfort and performance of individuals at work or sport is of particular importance because physiological loads may decline the physical and mental capacity of the person [4]. Also, various consumers consider comfort as one of the most important attributes in their purchase of apparel products; therefore companies tend to focus on the comfort of apparel products [2]. Intimate wear, which is described as human’s second skin, requires the comfort issue to be maintained perpetually than that of outerwear due to the contact to the skin directly. Also, the daily performance and good feeling of a person are synonymous with intimate apparel comfort characteristics.
\nWear comfort can be divided into four main aspects such as thermal comfort, sensorial comfort, body movement comfort, and aesthetic comfort. Thermal comfort is the satisfaction of a person with the thermal environment, and to do so there is a thermal balance between the human body and the environment and the proper balance between body heat production and heat loss. Thus, the person feels neither too cold nor too warm. In addition to heat transfer, moisture transport through the body-clothing-environment system is the main topic of the thermal comfort [2, 5]. Sensorial comfort refers to neural sensations when a fabric or garment comes into contact with human skin. It includes the warmth/coolness, prickliness, surface roughness, and electrical properties (e.g., static) of fabric against skin. Body movement comfort refers to the ability of a textile to allow freedom of movement [2]. Aesthetic comfort is the subjective perception by visual sensation which is influenced by color, style, garment fitting, fashion compatibility, fabric construction, and finish [1, 6].
\nFemale consumers, regardless of age and social status, are concerned with keeping up with the fashion trends though fashion items such as laced bras and thongs may be less comfortable to wear than daily bras and basic underwear. Despite an inherent incapacity to display the product, consumers feel they want it to be relevant and fashionable [7]. Thus, intimate apparel is invisible to the public, but it is considered as “inconspicuous fashion” [8].
\nBras allow the wearer to express their personality as they contribute to the final breast shape and contour visible through outer clothing that constructs a social identity [8]. Women may lose their youthful appearance after pregnancy, aging, or menopause. So, they would need a bra that makes the breasts look firm, round, and natural. The bra should uplift the drooping breasts to a desirable position with necessary fullness, coverage, and cleavage. On the other hand, the woman who has a plus size breast may suffer from social anxiety, low comfort level, and difficulty in their self-esteem, thinking that her outstanding breast causes shame [9]. Thus, many brands including Berlei, Victoria’s Secret, Triumph, and Bonds carry a wide range of bras that provide suitable comfort, support, and fit according to the needs of growing teens, working women, nursing mothers, and older women. Brands have also distinguished between different bra-wearing behaviors by differentiating the product into usage patterns, such as occasions and benefits sought (e.g., T-shirt bra designed for seamless everyday wear, push-up bras for enhanced cleavage, convertible bras for strapless or halter neck outfits, and sports bra for physical activities) [10].
\nThe main property of clothing is to build a stable microclimate next to the skin in order to maintain the body’s thermoregulatory system at different environmental and physical activity conditions, and provision of thermal balance is a function of the clothing in all wear situations. It acts as a barrier to heat and vapor transfer between skin and environment. Thermal comfort depends on several factors, heat and vapor transport, sweat absorption, and drying ability [4, 11], and it is an important criterion for intimate apparel in terms of feeling comfortable. Intimate apparel, being an inner layer in between the skin and outerwear, should be capable of maintaining heat balance between the excess heat produced by the wearer and the capacity of the clothing to dissipate body heat and perspiration. However, it exists within a narrow temperature range [12].
\nHuman body is homoeothermic and has to maintain its core temperature around 37°C, with a skin temperature between 30.7 and 35.6°C [13]. The body cells, especially in the organs and the muscles, produce heat that is partly released to the environment. This metabolic heat production can largely vary depending on the activity, from about 80 W at rest to over 1000 W during most strenuous efforts [2]. At an extreme activity, the heat produced in the muscles creates the greatest thermal stress. A large amount of this heat is often stored in the body resulting in an increase in body temperature [13, 14]. Then, the central nervous system gives indication to the hypothalamus of brain which controls the thermoregulation process. It sends signals to human organs, muscles, glands, and the nervous system. The excess heat is liberated to the outer environment by means of heat loss mechanism process [15]. Heat transfer continues until the two media are the same temperature and have reached equilibrium. The rate of the energy transferred depends on temperature difference and the degree of resistance between the two media [12]. Heat transfer from the body to the environment occurs in several ways [2, 13, 16]:
Dry heat transfer conduction (heat transfer between two surfaces in contact with each other), convection (heat exchange between a surface and a surrounding fluid, e.g., air or water), and radiation (emission or absorption of electromagnetic waves)
Evaporation of sweat
Heat transfer by respiration
In order to maintain the thermoregulation of a human body, heat generation and heat loss should ideally be equal. This principle can be expressed in a heat balance equation (Eq. (1)) (in W or W/m2) for the human body [2]:
\nwhere M is metabolic rate of the body, W is mechanical work, E is heat transfer by evaporation, R is heat transfer by radiation, C is heat transfer by convection, K is heat transfer by conduction, and S is heat storage.
\nThe enclosed still air and external air movement are the major factors that affect the heat transfer through fabric, and it is influenced by fabric construction, thickness, and material [4]. Fibers in a fabric structure serve two main functions in providing thermal insulation. Firstly, they develop air spaces and prevent air movement. Secondly, they provide a shield to heat loss from radiation. The efficiency of the thermal insulation of a fabric depends on fiber physical properties, such as fineness and shape, as well as the structure of fabric [5]. The higher the volume of dead air within a textile structure, the lower will be the thermal transmittance which results in higher thermal resistance [15]; man-made fibers can be produced with a degree of crimp or surface irregularity that increases thermal resistance [5]. Fabrics or garments made from hollow fibers can also provide better thermal insulation values due to the larger trapped air volume provided. Previous research shows that the amount of contact an item of clothing (such as a sports bra) has with the skin may affect thermoregulation. When the clothing fits tightly, there is less exchange of air beneath the clothing with the environment (“flushing”), and this can negatively affect thermoregulation [13]. Therefore, a sports bra, for example, can represent a physical advantage but a thermal disadvantage [13].
\nEvaporation is the body’s main method of heat dissipation during exercise and in hot environments [13]. Heavy sweat is formed in the body that leads to the accumulation of a lot of moisture or a thin film on the skin due to heat dissipation [4]. Sweating majorly acts as a heat loss mechanism of the body and cools where the sweat is being evaporated. Clothing actively affects the amount of sweat produced and the level of evaporation [13]. When fabric is subjected to heavy sweating conditions, not all the sweat absorbed by fabric can be given off to the atmosphere instantaneously. Thus to prevent the wearer from feeling wet and clammy [17], the sweat should be transported away from the skin surface body. The transportation of sweat may be in the form of liquid or vapor so that the fabric touching the skin feels dry [11, 15].
\nIn that respect, water vapor permeability is an important property that determines the capability of transporting perspiration through a textile material [15]. Water vapor permeability plays a very important role when there is only little sweating or insensible perspiration. The garment should have the ability to release the moisture vapor held in the microclimate to the atmosphere to reduce the dampness at the skin [4]. Impermeable structures, i.e., not permitting passage of water vapor to the surrounding atmosphere, increase the relative humidity of the microclimate inside the clothing and thermal conductivity of the insulating air, causing coolness and dampness. Water vapor transfer through textile materials may occur due to diffusion (driven by a water vapor concentration gradient) and convection (driven by an air pressure gradient) mechanisms [12]. Moisture transfer also involves adsorption, absorption, or desorption between the fibers and the surrounding air as well as the movement of condensed liquid water as a result of external forces, such as capillary pressure and gravity. Adsorption occurs when water molecules are attracted to the surface of a solid. A larger fiber surface area within a fabric can increase the amount of water adsorbed. In absorption, molecular moisture diffuses through the material. Desorption is the process of moisture release from adsorbed or absorbed water. The process of moisture absorption or desorption within textile materials absorbs or releases heat, which further complicates the heat transfer process [5]. The sweat absorption, spreading, and drying which determine how quickly the skin can be dried after sweating of a fabric decide the thermophysiological comfort property of the garment [18]. Therefore, fabrics with good moisture transport and drying properties are essential for intimate apparel which contact with skin directly.
\nDuring heavy activity when liquid perspiration production becomes high, to feel comfortable the clothing should possess good liquid transmission property. Wicking is an important property to uphold a feel of comfort during sweating conditions and is affected by fabric properties [4]. Discomfort is linked to the presence of liquid on the skin, and the removal of this, either by optimized evaporation or by wicking the moisture away from the skin, is thus a relevant factor [19]. Wicking is the spontaneous flow of liquid in a porous substrate, driven by capillary forces produced in the fabric. This is due to the wetting of fibers, and it causes the liquid to reach the spaces in between the fibers which gives a capillary action. Wicking fabrics can benefit comfort and cooling in two ways. When a person starts to sweat in garment, this sweat can be absorbed by fabric, spreading over a bigger area and thus facilitating evaporation. Also, by removing the liquid from the skin and transporting it away from the skin-fabric interface, clinging of clothing with its associated discomfort is reduced [4, 19]. The transport of liquid moisture is a complex mechanism dependent on the hydrophilic properties of the material (fibers), the inter- and intra-yarn capillaries, as well as the water absorption capacity (hygroscopicity) of fibers. These phenomena depend on the liquid surface tension, the size of the interstices, and wettability of fiber surface. The capillaries (interstices) in a fabric must form a continuous channel with the proper size. Parameters, such as fabric count, yarn linear density, and yarn twist, affect the size and number of fabric interstices. Fabrics with larger interstices normally allow rapid diffusion of water [20]. Sweat forming on the skin can be transported from the skin surface to the outer surface of the fabric by fabric wicking, where it evaporates to the environment and keeps the skin dry [5]. The spreading of liquid moisture can basically occur in two directions: spreading into the surface of the fabric (lateral wicking effect) or transfer of liquid from one side to the other (vertical wicking effect [2]). Also, moisture regain of a fiber affects wicking performance such that fiber with a larger moisture regain tends to decrease the wicking effect. In addition to these, the radius of capillaries is the key factor in deciding capillary effects [5].
\nDryarn, Coolmax, FIELDSENSOR™, fibers from Meryl product line, AKWATEK, Moiscare™ fibers, and the others, which will be discussed in detail in following section, provide high thermal comfort performance.
\nPeople must be able to move in the clothing that they wear. If clothing restrains movement, discomfort may result due to the pressure exerted on the body by the garment, and the clothing may fail [21]. A simple and ordinary body movement expands the skin by about 10–50%. Therefore, the strenuous movements require the least resistance from garment and instant recovery [22]. The dramatic difference between the skin’s elasticity and the lack of elasticity in conventional fabrics results in restriction of movement to the wearer and loss of shape, and consequent performance, of garments [9]. Minimizing a garment’s resistance to the body’s demands in movement can be achieved through increased fabric fullness in the pattern or through fabric stretch. Increasing the fabric’s stretch means garments can be cut to achieve a more streamlined appearance and can conform better to the body while still maintaining comfort for the wearer in motion [21]. Thus, intimate apparel should have stretch and elastic recovery to provide sufficient fit and freedom of movement to the wearer.
\nFitting is a crucial factor of wearing comfort particularly for the next-to-skin stretch garment. Despite attempts to standardize size, every female’s body shape is unique, which complicates the design process [8]. A good bra should fit the 3D complex body contours, to support the breast weight and to provide appropriate tension by well-fitted bottom band, straps, and cups [23]. However, perfect fit for bras is very difficult to achieve because it involves tedious trials and errors on manipulating the shape and support provided to the soft breasts of a live model [9]. Moreover, many pattern adaptations may be required to try different grain lines in the pattern and tension of fabric or changing the fabric and trims for better tension recovery [24]. However, women go through great difficulties to find a perfect-fitting bra to mold the body in a desirable silhouette [9]. A research conducted across western countries reports that at least around 70% of women wears the wrong size of bras [23]. This is not surprising because even within the same brand the bra size and thus bra fit change with the different styles [24]. The big problem of wearing the wrong bra contributes to poor posture due to the lack of support for the chest, and muscles have to do all the breast work. The breast is pulled by weight bra and causes pain on the back, neck, and back pain [9]. According to a study, the ability of a sports bra is reduced due to the poor bra fit which causes an increased breast discomfort [24].
\nCreating irritation in skin areas, bruises, and deep creases on the skin by elastic pressing the wrong place make the user feel uncomfortable [9]. It was found that the highest pressure was at the top of the shoulders and under the front elastic band. Costantakos and Watkins [23] suggested that a well-designed bra should prevent concentration of pressure on the sensitive areas such as veins and arteries near the skin surface. To limit the force generation and increase breast comfort level, the positive correlation between the mass of the breast and the vertical displacement suffering in their day by day has to be found. Also, the plus size bra can be the cause of numerous health problems related to the arms, neck, back, and head pain. For a plus size bra, it is advisable to use powernet or more than 20% elastane or lining for the wing or band part. The percentage of elastane will increase support in plus size breast that can be improved with the placement of a bone on the lateral side fitting [9]. Moreover, in the particular stage of a woman’s life, with the breast sagging, to create the right bra and the user choosing a more appropriate model, it is important to retain the biomechanical considerations. For pregnant women suffering from low back pain, maternity under garments could provide certain abdominal support and distribute the growing weight of fetus to the shoulder and the upper torso, which may help to relieve back pain and improve the wearer’s mobility [23].
\nGarments including fibers such as LYCRA® W from the Lycra Company, the Meryl Elite® from Nylstar, and ISCRA-S from Sorona offer comfort in terms of fit, shape retention, and freedom of movement.
\nSensorial comfort is the sensation of how the fabric feels when it is worn near to the skin. The tribology of skin in contact with textiles is important in connection with the comfort of clothing, because the tactile properties of fabrics are closely related to their surface and frictional properties. Sensorial comfort is very difficult to predict as it involves a large number of different factors, and this feeling addresses properties of the fabric like prickling, itching, stiffness, or smoothness [2]. In addition, a good performance of movements is always combined with the use of suitable materials and intimate apparel; the proportion of the body has to be assessed so that the product used is the most appropriate for those wearing it [9]. In addition, wet skin is much more easily irritated than dry skin.
\nExperimental studies showed that raw materials and structural properties of fabrics are important in the determination of tactile properties of fabrics. Suda and Tamura [23] tried to estimate comfort with the help of the tactile sensations like smoothness, softness, and stickiness of underwear fabrics despite the change in air temperature. According to Nielsen et al. [25], knit structures of the underwear influenced sensations of humidity significantly, but not sensations of temperature. The various sensations of temperature correlated best with core temperature, whereas the sensations of humidity correlated with skin wetness. The study which assesses the tactile comfort according to 10 descriptors (soft, thin, smooth, warm, dry, light, loose, sheer, stiff, and pleasant tactile sensation) conducted by Kweon et al. [23] implied that men usually preferred all cotton, while women selected man-made fabrics. In addition, at intimate apparel lace and embroidery are used so often which prick the skin. Also, poor seam coverings or loose threads also bring skin irritation. To minimize the seams and stitches, various sew-free technologies have been widely applied. The bra cup seams have been eliminated by molded cups; the elastic band has been replaced by Bemis thermoplastic polyurethane (TPU) film or Lycra 2.0 polyurethaneurea (PUU) heat-activated elastic adhesive tape. Thread and stitches disappear when the hemming operation uses ultrasonic bonding with hooks and eyes integrally attached onto the inner surface of the back wing panel. Brand and size labels are seamlessly printed [23]. A study of 1285 female marathon runners found 28% frequently experienced problems with sports bras rubbing or chaffing which is a typical example of the importance of sensorial comfort which if ignored may lead to minor injuries [24]. Moreover, women have sensitive skin especially during puberty and pregnancy.
\nTACTEL® fiber from Invista, Sensil® Body Fresh, and chitin are some examples for the novel fibers that maintain good sensorial comfort.
\n“A fiber is a unit of matter, either natural or manufactured, characterized by flexibility, fineness and a high ratio of length to thickness” [26]. The use of natural fibers dates back to 4000 years ago, and they were the fibers used first. Cotton, wool, silk, and all other animal and plant fibers fall in the category of natural fibers. The first attempt to make an artificial fiber was done in the year 1664. However, it was almost 200 years later when the first success was achieved. Man-made fibers became a significant alternative to natural fibers after the 1950s. The development of these fibers opened up fiber applications to various fields like medicine, agriculture, home furnishing, modern apparels, etc. [27, 28]. The timetable of fibers covers four generations [29]:
Before the 1950s, natural fibers were used, and they are termed as first-generation fibers.
After the 1950s, second-generation fibers, man-made regenerated and synthetic ones, were introduced.
Third-generation fibers came in the 1980s. This generation covered specialty fibers, high-performance/high functional fibers, and high technology fibers.
Super fibers, smart fibers, and nanofibers, which are called new fibers, are the fourth-generation fibers that came after 1985. These fibers give a new dimension to the use of textiles.
As of today, latest trends and innovations in man-made fiber and textile industry can be roughly identified and classified as follows [30]:
Sustainability
Development of functional textile
Development of smart textile
Manufacturing innovations
Materials engineering
Unconventional applications
High-technology fiber is a general term used for fibers made by different methods from ordinary methods, and they are the ones which have improved performance such as high melting point and high decomposition temperature. These high-function fibers are developed according to needs of the user and provide higher comfort, easy-care properties. Functional textiles have additional functionalities like flame resistance, breathability, thermoregulation, stain resistance, being antimicrobial, electro conductivity, etc. [31].
\nCommon types of fibers currently used in intimate apparel are cotton, silk, rayon, nylon, polyester, and spandex. Performance and versatility of intimate apparel such as easy-care properties, light weight, durability, ease of movement, having antibacterial or anti-odor properties, and good moisture management are further improved by the use of new fibers. In this section the latest developments in fibers used in the manufacturing of intimate apparel products and their contribution to clothing comfort are discussed [32].
\nFibers which attribute ease of movement to intimate garments have superior stretch and recovery properties:
\nLYCRA® is a synthetic elastane fiber that can stretch up to about six times its initial length and return to its original state repeatedly. Garments including LYCRA® fiber offer comfort, fit, shape retention, and freedom of movement. The fiber can be used in close-to-the-body garments such intimate apparel as well as pantyhose, hosiery, active wear, and swimwear [33].
\nLYCRA® W technology offered by the Lycra Company elevates the performance of intimate apparel made from warp or circular knit fabrics. “W” elastane fibers with luster permit the garments to deliver outstanding whiteness, whiteness retention, uniformity, and dye pickup for deeper, richer colors. Fabrics made with these fibers also have better resistance to elastane yellowing from heat-setting, exposure to fumes, and UV light [34].
\nFor intimates, body wear, sportswear, etc., different types of polyamide microfibers are offered by Nylstar through the Meryl® product line.
\nMeryl Elite provides a convenient partnership to elastane in single and double covered yarns (Figure 1) offering a good performance for tights, socks, and leggings. Microfilaments of Meryl Elite give lightness, smoothness, high elasticity, durability, and comfort to the garments [35].
\nCovered yarn structure [
ISCRA-S is a highly elastic material-like spandex. It is a bicomponent fiber from Sorona, a material extracted from corn, and PET. After the finishing processes are applied, it gains a spring-like structure (Figure 2) [36].
\nISCRA-S fiber before and after finishing process [
The fiber is suitable to be used in underwear, sportswear, outdoor wear, etc. due to its comfort stretch and good stretch recovery as well as quick moisture absorbing and drying properties.
\nECOWAY-Sorona from corn is a soft touch fiber from shape memory material recommended for intimate apparel. Textiles from ECOWAY-Sorona are naturally crumpled and smoothly unfolded due to the shape memory property [37].
\nTo improve moisture management properties of intimate apparel, breathable fibers with modified cross section have been developed to enhance the wearer’s comfort. Fibers and yarns that possess improved moisture management properties are discussed in the following section:
\nTENCEL™ Intimate cellulosic fibers, lyocell, and modal are produced by sustainable processes from natural, renewable raw material, wood. TENCEL™ lyocell fibers absorb moisture more effectively than synthetic fibers, and there is less moisture formed on the fiber. The fibrils of cellulosic fibers regulate the absorption and release of moisture. This leads to less favorable media for bacterial growth, and consequently better hygienic qualities are offered. This also enhances breathability of the garment and keeps the skin cool and dry. One of the key factors in choosing materials for intimate apparel is softness. The smooth surface of TENCEL™ Intimate cellulosic fibers also offers a gentle touch to the skin. High flexibility and low rigidity of fine TENCEL Modal fibers result in a soft feeling twice as soft as cotton [38].
\nFIELDSENSOR™, developed by Toray, applies the principles of capillary transport to the structure of knitwear enabling absorption, movement, dispersion, and evaporation of perspiration from the skin. By this way, the perspiration-induced stickiness and clinginess of traditional materials are eliminated. It offers good moisture management functions for running, fitness, and training suits [39, 40].
\nFlat multi-microfibers as fine as 0.45 dpf (dtex per filament) of Meryl® Sublime, from Nylstar’s Meryl® product line, quickly draw perspiration away from the skin to the exterior of the fabric. The fiber is highly demanded for intimates and swimwear due to its special handle, silky touch, light weight, and breathability [41].
\nMeryl® Nateo is an air-textured polyamide yarn with a round cross section. The main properties of Meryl Nateo, namely, UV productivity, water absorption, breathability, and stretch ability, make the fiber suitable to be used in body wear, sport, swimwear, or intimates [42].
\nTrilobal cross section of Meryl Satiné reflects the light perfectly and provides garments with a remarkable shine comparable to silk (Figure 3). Meryl Satiné is preferred for many applications due to its excellent moisture-wicking properties, breathability, and natural elasticity [43].
\nTrilobal cross section of Meryl Satiné [
Dryarn is a breathable “isostatic polypropylene microfiber” which offers intense performance in terms of lightness, drying, and wicking, with no penalty in the thermal insulation properties specific to polypropylene. It also has a higher capacity for removing moisture compared to polyester [44, 45].
\nNILIT®, a manufacturer of nylon 6.6 fibers, offers fashion body wear, active wear, legwear, and intimate apparel. Sensil is a new Nylon 6.6 brand created by NILIT®. Sensil® Aquarius has built-in moisture management properties thanks to its special triple T-cross section which forms special micro-channels in the fiber and increases the surface area for improved moisture management (Figure 4) [46, 47].
\nT-cross section of Sensil® Aquarius [
Supplex®, a registered trademark of Invista and licensed by NILIT® for nylon fiber products, provides functional benefits for intimate apparel, active wear/fitness, etc. with an exceptionally smooth, natural hand due to the presence of finer, multiple nylon filaments and dries up to four times faster than cotton. Supplex® also has permanent protection due to the intrinsic UPF protection qualities [49].
\nCoolmax is an advanced polyester yarn mainly used for thermoactive underwear, intimate apparel, sport underwear, and sportswear. A capillary transport system maintained by special four- or six-channeled fiber morphology pulls moisture away from the skin, transfers to the outer layer of the fabric, and dries quickly. It’s much convenient for sport applications due to high thermal control under physical stress [50, 51].
\nCoolmax freshFX, on the other hand, is a suitable fiber for intimate apparel which combines the Coolmax® moisture management and odor shield antimicrobial fiber technologies. Coolmax® freshFX™ is designed by incorporating a silver-based additive to Coolmax. Coolmax® freshFX™ fabrics actively suppress the growth of bacteria which are responsible for body odor and related smells. Coolmax® freshFX™ garments keep the wearer cool and dry while keeping clothes smelling clean and fresh longer [52].
\nTACTEL® fiber from Invista is a form of nylon fiber which is widely used in women’s intimate apparel because of its soft and lightweight nature, quick drying, easy care, breathability, and abrasion-resistant properties [53, 54].
\nNike Dri-FIT technology uses microfibers to support the body’s natural cooling system by wicking away sweat. The moistures is, then, dispersed evenly throughout the surface of the garment and evaporates quickly. Dri-FIT fabrics can be made of nylon, polyester, spandex, or a blend of all three but mostly in the form of microfibers. It is proposed that it should be worn next to the skin to keep the body dry [55].
\nConsumers’ awareness of hygiene and active lifestyle has created an increasing demand for antimicrobial/anti-odor textiles. Bacteriostatic fabrics prevent the proliferation of microorganisms and production of unpleasant odor. The formation of fungal growth is also slowed down by the use novel fibers offered.
\nNormally, some amount of bacteria is present on human skin. Not only the presence of a high level of bacteria but also its complete absence creates various problems such as allergy, odor, illness, etc. While exercising, bacteria are transferred to the textile and with conventional nylon fibers; these bacteria can proliferate and grow very quickly. With the inherent silver microparticles, Meryl Skinlife prevents bacteria growth, maintains the natural balance of the skin, and reduces unpleasant odor [56].
\nMeryl Nexten from Nylstar is a hollow polyamide fiber with inherent silver microparticles (Figure 5). Its hollow structure provides the production of 20% lighter fabrics with the same thickness and insulation of the body against temperature variations. The presence of silver microparticle Meryl Nexten offers an antimicrobial effect [57].
\nHollow polyamide fiber Meryl Nexten from Nylstar [
Chitin is a biocompatible compound obtained from the shell of crab and shellfish. Chitosan is a product derived from Chitin. A new fiber Crabyon® is a blend of chitosan and viscose which has permanent antibacterial functions. The fiber is suitable for weak and sensitive skin since it prevents the skin from drying out. Due to Crabyon’s velvety touch and other properties, it is recommended to be used in intimate apparel [58].
\nSensil® Body Fresh makes sure the garments do not have unpleasant odor thanks to the antibacterial additive embedded in the fiber [59].
\nWith its excellent disinfection power due to the silver ions held in the acrylic fibers, PURECELL™ and a deodorizing fiber preventing unpleasant smell by absorbing the ammonia CELFINEN™ are fibers recommended for underwear by TOYOBO [60, 61].
\nX-STATIC® silver fiber from Noble Fiber Technologies also utilizes the power of silver to inhibit the growth of bacteria on fabrics and to eliminate human-based odor. 99.9% metallic silver is bonded to the surface of a fiber X-STATIC® permanently. One hundred percent coverage area of silver on the fiber gives products with X-STATIC® a maximized performance with soft, flexible, and comfortable features [62].
\nTruFresh from Unifi is recommended for yoga pants, socks, hosiery, etc., for its odor-killing performance by inhibiting the growth of odor-causing bacteria, mold, mildew, and algae on fabrics. For optimal performance, it is recommended that the fabric contains at least 30% TruFresh by weight [63].
\nThermal comfort is related to the efficiency of heat dissipation from a clothed human body. One of the primary functions of underwear is to act as a buffer against environmental changes to maintain a thermal balance between the body heat and the heat lost to the environment while allowing the skin to remain free of liquid water. Thermal comfort is provided by the use of recently developed fibers [1].
\nAKWATEK is a modified polyester fiber with active surface layer with anionic end groups. The active surface transports water molecules and releases them to the atmosphere before they can form liquid water. Thanks to AKWATEK’s enhanced properties, thermoregulatory actions of the body are duplicated, and moisture is pulled away from the body much faster than capillary action fabrics. AKWATEK has the ability of keeping the wearer cool in warm temperatures and warm in cold temperatures. It is used in fabrics with Lycra—for apparel tops and tank tops, sport bras, turtlenecks, tights, and leggings [23, 64].
\nQuick transfer of heat from the body is maintained by the wide surface area of the fiber with flat cross section, and comfort is enhanced by the cooling effect and efficient ventilation of Sensil® Breeze (Figure 6). The presence of inorganic micron particles in the polymer further increases the surface area and contributes to the cooling effect [65].
\nSensil® Breeze [
The use of Sensil® Heat in knitted garments provides a delay in heat transfer from the body to the outside. Coffee charcoal, from coffee bean shell residue, is integrated in the yarn together with an oxide additive which captures and keeps body heat. It is claimed that the insulation activity is most effective when the fabric is used nearest to the body [65].
\nAnother fiber recommended for underwear, sports apparel, bed clothes, etc. is an acrylate fiber, Moiscare™, which is a registered trademark of the Japanese firm TOYOBO. The fiber has heat-generating ability when absorbing moisture. It is claimed that the exothermic energy is about three times higher than that of wool. Depending on the atmospheric conditions, it can absorb and release moisture repeatedly. It also has the ability of deodorizing ammonium gas and others [67].
\nThermolite FIR technology from Invista is a spun-dyed black fiber in which special ceramic pigments are embedded. The fiber, recommended for legwear, absorbs the wearer’s infrared radiation and reflects it back as heat energy and raises skin temperature by around 1°C [68].
\nOutlast® technology manages moisture by reacting to sweat and pulling it away from the skin and proactively manages heat while controlling the production of moisture before it begins. It utilizes phase change materials (PCM) that absorb, store, and release heat for optimal thermal comfort. Outlast® phase change materials can be located inside the fiber. In-fiber applications are for products being worn next to or very close to the skin. Outlast® viscose is a versatile fiber commonly used for underwear, shirts, dresses, sleepwear, work wear, and sportswear (Figure 7). The fiber provides softness and comfort similar to cotton or silk [69, 70].
\nOutlast® viscose fiber [
Intimate apparel ensures primarily the comfort of people as it contacts with the skin directly and forms an inner layer between the skin and outerwear. To provide intimate apparel comfort, thermal, aesthetical, sensorial, hygienic, and motional performances are required which are mostly related to fiber properties. Thus, the investigations to develop new fibers which provide better comfort performances are carried on by major fiber manufacturers. This chapter presents a detailed review of comfort from intimate apparel side, and also developed novel fibers which are recommended to be used for performing intimate apparel comfort were introduced.
\nAs an Open Access publisher, IntechOpen is dedicated to maintaining the highest ethical standards and principles in publishing. In addition, IntechOpen promotes the highest standards of integrity and ethical behavior in scientific research and peer-review. To maintain these principles IntechOpen has developed basic guidelines to facilitate the avoidance of Conflicts of Interest.
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The psychosocial predictors, along with hopelessness and non-suicidal injury (NSSI), have not been studied properly before. Therefore, there is a need to address these issues. The objective of the study was to ascertain the psychosocial and clinical features predicting suicide and NSSI in adolescents with major depression. Increased number of suicidality and impaired family function at entry is autonomously connected with a suicidal attempt. NSSI are connected at base line and apply additive effect on likelihood, one keeping on through treatment period. Poor family functions, as well as family problems and social problems, were the causative agents for adolescent’s high suicidality and NSSI. A history of NSSI treatment is a clinical marker for suicidality. The previous suicidal attempts should be evaluated in depressed juvenile patients as indicators of future suicidal intent and behavior. Both suicidal and NSSI adolescents during the therapy and after treatment endure to be depressed when they are engaged in study. 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The model is discussed with reference to the types of multivariate treatment applied in a particular programme which works interactively online using an electronic data-base for linking functional difficulties in learning to treatment, and through this to firm diagnosis and classification. In applying the model, initial diagnosis of learning disabilities is treated as provisional, based on functional indicators as well as test data. Firm classification becomes possible through longitudinal assessment, analysis of response to multivariate intervention as well as response to specific programmes. Diagnosis can then be linked both to concessions as well as ongoing treatment.",book:{id:"10910",slug:"learning-disabilities-neurobiology-assessment-clinical-features-and-treatments",title:"Learning Disabilities",fullTitle:"Learning Disabilities - Neurobiology, Assessment, Clinical Features and Treatments"},signatures:"Charles Potter",authors:[{id:"93190",title:"Dr.",name:"Charles",middleName:null,surname:"Potter",slug:"charles-potter",fullName:"Charles Potter"}]}],onlineFirstChaptersFilter:{topicId:"233",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:87,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:98,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:27,numberOfPublishedChapters:287,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:9,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:139,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:129,numberOfOpenTopics:0,numberOfUpcomingTopics:2,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!1},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:10,numberOfPublishedChapters:103,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:2,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:0,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!1},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:10,numberOfOpenTopics:4,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. 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Radiotherapy and Nuclear Medicine Technology has always been my aspiration and my life. As years passed I accumulated a tremendous amount of skills and knowledge in Radiotherapy and Nuclear Medicine, Conventional Radiology, Radiation Protection, Bioinformatics Technology, PACS, Image processing, clinically and lecturing that will enable me to provide a valuable service to the community as a Researcher and Consultant in this field. My method of translating this into day to day in clinical practice is non-exhaustible and my habit of exchanging knowledge and expertise with others in those fields is the code and secret of success.",institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"313277",title:"Dr.",name:"Bartłomiej",middleName:null,surname:"Płaczek",slug:"bartlomiej-placzek",fullName:"Bartłomiej Płaczek",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/313277/images/system/313277.jpg",biography:"Bartłomiej Płaczek, MSc (2002), Ph.D. (2005), Habilitation (2016), is a professor at the University of Silesia, Institute of Computer Science, Poland, and an expert from the National Centre for Research and Development. His research interests include sensor networks, smart sensors, intelligent systems, and image processing with applications in healthcare and medicine. He is the author or co-author of more than seventy papers in peer-reviewed journals and conferences as well as the co-author of several books. He serves as a reviewer for many scientific journals, international conferences, and research foundations. Since 2010, Dr. Placzek has been a reviewer of grants and projects (including EU projects) in the field of information technologies.",institutionString:"University of Silesia",institution:{name:"University of Silesia",country:{name:"Poland"}}},{id:"35000",title:"Prof.",name:"Ulrich H.P",middleName:"H.P.",surname:"Fischer",slug:"ulrich-h.p-fischer",fullName:"Ulrich H.P Fischer",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/35000/images/3052_n.jpg",biography:"Academic and Professional Background\nUlrich H. P. has Diploma and PhD degrees in Physics from the Free University Berlin, Germany. He has been working on research positions in the Heinrich-Hertz-Institute in Germany. Several international research projects has been performed with European partners from France, Netherlands, Norway and the UK. He is currently Professor of Communications Systems at the Harz University of Applied Sciences, Germany.\n\nPublications and Publishing\nHe has edited one book, a special interest book about ‘Optoelectronic Packaging’ (VDE, Berlin, Germany), and has published over 100 papers and is owner of several international patents for WDM over POF key elements.\n\nKey Research and Consulting Interests\nUlrich’s research activity has always been related to Spectroscopy and Optical Communications Technology. Specific current interests include the validation of complex instruments, and the application of VR technology to the development and testing of measurement systems. He has been reviewer for several publications of the Optical Society of America\\'s including Photonics Technology Letters and Applied Optics.\n\nPersonal Interests\nThese include motor cycling in a very relaxed manner and performing martial arts.",institutionString:null,institution:{name:"Charité",country:{name:"Germany"}}},{id:"341622",title:"Ph.D.",name:"Eduardo",middleName:null,surname:"Rojas Alvarez",slug:"eduardo-rojas-alvarez",fullName:"Eduardo Rojas Alvarez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/341622/images/15892_n.jpg",biography:null,institutionString:null,institution:{name:"University of Cuenca",country:{name:"Ecuador"}}},{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/215610/images/system/215610.jpeg",biography:"Muhammad Sarfraz is a professor in the Department of Information Science, Kuwait University, Kuwait. His research interests include optimization, computer graphics, computer vision, image processing, machine learning, pattern recognition, soft computing, data science, and intelligent systems. Prof. Sarfraz has been a keynote/invited speaker at various platforms around the globe. He has advised/supervised more than 110 students for their MSc and Ph.D. theses. He has published more than 400 publications as books, journal articles, and conference papers. He has authored and/or edited around seventy books. Prof. Sarfraz is a member of various professional societies. He is a chair and member of international advisory committees and organizing committees of numerous international conferences. He is also an editor and editor in chief for various international journals.",institutionString:"Kuwait University",institution:{name:"Kuwait University",country:{name:"Kuwait"}}},{id:"32650",title:"Prof.",name:"Lukas",middleName:"Willem",surname:"Snyman",slug:"lukas-snyman",fullName:"Lukas Snyman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/32650/images/4136_n.jpg",biography:"Lukas Willem Snyman received his basic education at primary and high schools in South Africa, Eastern Cape. He enrolled at today's Nelson Metropolitan University and graduated from this university with a BSc in Physics and Mathematics, B.Sc Honors in Physics, MSc in Semiconductor Physics, and a Ph.D. in Semiconductor Physics in 1987. After his studies, he chose an academic career and devoted his energy to the teaching of physics to first, second, and third-year students. After positions as a lecturer at the University of Port Elizabeth, he accepted a position as Associate Professor at the University of Pretoria, South Africa.\r\n\r\nIn 1992, he motivates the concept of 'television and computer-based education” as means to reach large student numbers with only the best of teaching expertise and publishes an article on the concept in the SA Journal of Higher Education of 1993 (and later in 2003). The University of Pretoria subsequently approved a series of test projects on the concept with outreach to Mamelodi and Eerste Rust in 1993. In 1994, the University established a 'Unit for Telematic Education ' as a support section for multiple faculties at the University of Pretoria. In subsequent years, the concept of 'telematic education” subsequently becomes well established in academic circles in South Africa, grew in popularity, and is adopted by many universities and colleges throughout South Africa as a medium of enhancing education and training, as a method to reaching out to far out communities, and as a means to enhance study from the home environment.\r\n\r\nProfessor Snyman in subsequent years pursued research in semiconductor physics, semiconductor devices, microelectronics, and optoelectronics.\r\n\r\nIn 2000 he joined the TUT as a full professor. Here served for a period as head of the Department of Electronic Engineering. Here he makes contributions to solar energy development, microwave and optoelectronic device development, silicon photonics, as well as contributions to new mobile telecommunication systems and network planning in SA.\r\n\r\nCurrently, he teaches electronics and telecommunications at the TUT to audiences ranging from first-year students to Ph.D. level.\r\n\r\nFor his research in the field of 'Silicon Photonics” since 1990, he has published (as author and co-author) about thirty internationally reviewed articles in scientific journals, contributed to more than forty international conferences, about 25 South African provisional patents (as inventor and co-inventor), 8 PCT international patent applications until now. Of these, two USA patents applications, two European Patents, two Korean patents, and ten SA patents have been granted. A further 4 USA patents, 5 European patents, 3 Korean patents, 3 Chinese patents, and 3 Japanese patents are currently under consideration.\r\n\r\nRecently he has also published an extensive scholarly chapter in an internet open access book on 'Integrating Microphotonic Systems and MOEMS into standard Silicon CMOS Integrated circuitry”.\r\n\r\nFurthermore, Professor Snyman recently steered a new initiative at the TUT by introducing a 'Laboratory for Innovative Electronic Systems ' at the Department of Electrical Engineering. The model of this laboratory or center is to primarily combine outputs as achieved by high-level research with lower-level system development and entrepreneurship in a technical university environment. Students are allocated to projects at different levels with PhDs and Master students allocated to the generation of new knowledge and new technologies, while students at the diploma and Baccalaureus level are allocated to electronic systems development with a direct and a near application for application in industry or the commercial and public sectors in South Africa.\r\n\r\nProfessor Snyman received the WIRSAM Award of 1983 and the WIRSAM Award in 1985 in South Africa for best research papers by a young scientist at two international conferences on electron microscopy in South Africa. He subsequently received the SA Microelectronics Award for the best dissertation emanating from studies executed at a South African university in the field of Physics and Microelectronics in South Africa in 1987. In October of 2011, Professor Snyman received the prestigious Institutional Award for 'Innovator of the Year” for 2010 at the Tshwane University of Technology, South Africa. This award was based on the number of patents recognized and granted by local and international institutions as well as for his contributions concerning innovation at the TUT.",institutionString:null,institution:{name:"University of South Africa",country:{name:"South Africa"}}},{id:"317279",title:"Mr.",name:"Ali",middleName:"Usama",surname:"Syed",slug:"ali-syed",fullName:"Ali Syed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/317279/images/16024_n.png",biography:"A creative, talented, and innovative young professional who is dedicated, well organized, and capable research fellow with two years of experience in graduate-level research, published in engineering journals and book, with related expertise in Bio-robotics, equally passionate about the aesthetics of the mechanical and electronic system, obtained expertise in the use of MS Office, MATLAB, SolidWorks, LabVIEW, Proteus, Fusion 360, having a grasp on python, C++ and assembly language, possess proven ability in acquiring research grants, previous appointments with social and educational societies with experience in administration, current affiliations with IEEE and Web of Science, a confident presenter at conferences and teacher in classrooms, able to explain complex information to audiences of all levels.",institutionString:null,institution:{name:"Air University",country:{name:"Pakistan"}}},{id:"75526",title:"Ph.D.",name:"Zihni Onur",middleName:null,surname:"Uygun",slug:"zihni-onur-uygun",fullName:"Zihni Onur Uygun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/75526/images/12_n.jpg",biography:"My undergraduate education and my Master of Science educations at Ege University and at Çanakkale Onsekiz Mart University have given me a firm foundation in Biochemistry, Analytical Chemistry, Biosensors, Bioelectronics, Physical Chemistry and Medicine. After obtaining my degree as a MSc in analytical chemistry, I started working as a research assistant in Ege University Medical Faculty in 2014. In parallel, I enrolled to the MSc program at the Department of Medical Biochemistry at Ege University to gain deeper knowledge on medical and biochemical sciences as well as clinical chemistry in 2014. In my PhD I deeply researched on biosensors and bioelectronics and finished in 2020. Now I have eleven SCI-Expanded Index published papers, 6 international book chapters, referee assignments for different SCIE journals, one international patent pending, several international awards, projects and bursaries. In parallel to my research assistant position at Ege University Medical Faculty, Department of Medical Biochemistry, in April 2016, I also founded a Start-Up Company (Denosens Biotechnology LTD) by the support of The Scientific and Technological Research Council of Turkey. Currently, I am also working as a CEO in Denosens Biotechnology. The main purposes of the company, which carries out R&D as a research center, are to develop new generation biosensors and sensors for both point-of-care diagnostics; such as glucose, lactate, cholesterol and cancer biomarker detections. My specific experimental and instrumental skills are Biochemistry, Biosensor, Analytical Chemistry, Electrochemistry, Mobile phone based point-of-care diagnostic device, POCTs and Patient interface designs, HPLC, Tandem Mass Spectrometry, Spectrophotometry, ELISA.",institutionString:null,institution:{name:"Ege University",country:{name:"Turkey"}}},{id:"246502",title:"Dr.",name:"Jaya T.",middleName:"T",surname:"Varkey",slug:"jaya-t.-varkey",fullName:"Jaya T. Varkey",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246502/images/11160_n.jpg",biography:"Jaya T. Varkey, PhD, graduated with a degree in Chemistry from Cochin University of Science and Technology, Kerala, India. She obtained a PhD in Chemistry from the School of Chemical Sciences, Mahatma Gandhi University, Kerala, India, and completed a post-doctoral fellowship at the University of Minnesota, USA. She is a research guide at Mahatma Gandhi University and Associate Professor in Chemistry, St. Teresa’s College, Kochi, Kerala, India.\nDr. Varkey received a National Young Scientist award from the Indian Science Congress (1995), a UGC Research award (2016–2018), an Indian National Science Academy (INSA) Visiting Scientist award (2018–2019), and a Best Innovative Faculty award from the All India Association for Christian Higher Education (AIACHE) (2019). She Hashas received the Sr. Mary Cecil prize for best research paper three times. She was also awarded a start-up to develop a tea bag water filter. \nDr. Varkey has published two international books and twenty-seven international journal publications. She is an editorial board member for five international journals.",institutionString:"St. Teresa’s College",institution:null},{id:"250668",title:"Dr.",name:"Ali",middleName:null,surname:"Nabipour Chakoli",slug:"ali-nabipour-chakoli",fullName:"Ali Nabipour Chakoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/250668/images/system/250668.jpg",biography:"Academic Qualification:\r\n•\tPhD in Materials Physics and Chemistry, From: Sep. 2006, to: Sep. 2010, School of Materials Science and Engineering, Harbin Institute of Technology, Thesis: Structure and Shape Memory Effect of Functionalized MWCNTs/poly (L-lactide-co-ε-caprolactone) Nanocomposites. Supervisor: Prof. Wei Cai,\r\n•\tM.Sc in Applied Physics, From: 1996, to: 1998, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Determination of Boron in Micro alloy Steels with solid state nuclear track detectors by neutron induced auto radiography, Supervisors: Dr. M. Hosseini Ashrafi and Dr. A. Hosseini.\r\n•\tB.Sc. in Applied Physics, From: 1991, to: 1996, Faculty of Physics & Nuclear Science, Amirkabir Uni. of Technology, Tehran, Iran, Thesis: Design of shielding for Am-Be neutron sources for In Vivo neutron activation analysis, Supervisor: Dr. M. Hosseini Ashrafi.\r\n\r\nResearch Experiences:\r\n1.\tNanomaterials, Carbon Nanotubes, Graphene: Synthesis, Functionalization and Characterization,\r\n2.\tMWCNTs/Polymer Composites: Fabrication and Characterization, \r\n3.\tShape Memory Polymers, Biodegradable Polymers, ORC, Collagen,\r\n4.\tMaterials Analysis and Characterizations: TEM, SEM, XPS, FT-IR, Raman, DSC, DMA, TGA, XRD, GPC, Fluoroscopy, \r\n5.\tInteraction of Radiation with Mater, Nuclear Safety and Security, NDT(RT),\r\n6.\tRadiation Detectors, Calibration (SSDL),\r\n7.\tCompleted IAEA e-learning Courses:\r\nNuclear Security (15 Modules),\r\nNuclear Safety:\r\nTSA 2: Regulatory Protection in Occupational Exposure,\r\nTips & Tricks: Radiation Protection in Radiography,\r\nSafety and Quality in Radiotherapy,\r\nCourse on Sealed Radioactive Sources,\r\nCourse on Fundamentals of Environmental Remediation,\r\nCourse on Planning for Environmental Remediation,\r\nKnowledge Management Orientation Course,\r\nFood Irradiation - Technology, Applications and Good Practices,\r\nEmployment:\r\nFrom 2010 to now: Academic staff, Nuclear Science and Technology Research Institute, Kargar Shomali, Tehran, Iran, P.O. Box: 14395-836.\r\nFrom 1997 to 2006: Expert of Materials Analysis and Characterization. Research Center of Agriculture and Medicine. Rajaeeshahr, Karaj, Iran, P. O. Box: 31585-498.",institutionString:"Atomic Energy Organization of Iran",institution:{name:"Atomic Energy Organization of Iran",country:{name:"Iran"}}},{id:"248279",title:"Dr.",name:"Monika",middleName:"Elzbieta",surname:"Machoy",slug:"monika-machoy",fullName:"Monika Machoy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/248279/images/system/248279.jpeg",biography:"Monika Elżbieta Machoy, MD, graduated with distinction from the Faculty of Medicine and Dentistry at the Pomeranian Medical University in 2009, defended her PhD thesis with summa cum laude in 2016 and is currently employed as a researcher at the Department of Orthodontics of the Pomeranian Medical University. She expanded her professional knowledge during a one-year scholarship program at the Ernst Moritz Arndt University in Greifswald, Germany and during a three-year internship at the Technical University in Dresden, Germany. She has been a speaker at numerous orthodontic conferences, among others, American Association of Orthodontics, European Orthodontic Symposium and numerous conferences of the Polish Orthodontic Society. She conducts research focusing on the effect of orthodontic treatment on dental and periodontal tissues and the causes of pain in orthodontic patients.",institutionString:"Pomeranian Medical University",institution:{name:"Pomeranian Medical University",country:{name:"Poland"}}},{id:"252743",title:"Prof.",name:"Aswini",middleName:"Kumar",surname:"Kar",slug:"aswini-kar",fullName:"Aswini Kar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252743/images/10381_n.jpg",biography:"uploaded in cv",institutionString:null,institution:{name:"KIIT University",country:{name:"India"}}},{id:"204256",title:"Dr.",name:"Anil",middleName:"Kumar",surname:"Kumar Sahu",slug:"anil-kumar-sahu",fullName:"Anil Kumar Sahu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204256/images/14201_n.jpg",biography:"I have nearly 11 years of research and teaching experience. I have done my master degree from University Institute of Pharmacy, Pt. Ravi Shankar Shukla University, Raipur, Chhattisgarh India. I have published 16 review and research articles in international and national journals and published 4 chapters in IntechOpen, the world’s leading publisher of Open access books. I have presented many papers at national and international conferences. I have received research award from Indian Drug Manufacturers Association in year 2015. My research interest extends from novel lymphatic drug delivery systems, oral delivery system for herbal bioactive to formulation optimization.",institutionString:null,institution:{name:"Chhattisgarh Swami Vivekanand Technical University",country:{name:"India"}}},{id:"253468",title:"Dr.",name:"Mariusz",middleName:null,surname:"Marzec",slug:"mariusz-marzec",fullName:"Mariusz Marzec",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/253468/images/system/253468.png",biography:"An assistant professor at Department of Biomedical Computer Systems, at Institute of Computer Science, Silesian University in Katowice. Scientific interests: computer analysis and processing of images, biomedical images, databases and programming languages. He is an author and co-author of scientific publications covering analysis and processing of biomedical images and development of database systems.",institutionString:"University of Silesia",institution:null},{id:"212432",title:"Prof.",name:"Hadi",middleName:null,surname:"Mohammadi",slug:"hadi-mohammadi",fullName:"Hadi Mohammadi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/212432/images/system/212432.jpeg",biography:"Dr. Hadi Mohammadi is a biomedical engineer with hands-on experience in the design and development of many engineering structures and medical devices through various projects that he has been involved in over the past twenty years. Dr. Mohammadi received his BSc. and MSc. degrees in Mechanical Engineering from Sharif University of Technology, Tehran, Iran, and his PhD. degree in Biomedical Engineering (biomaterials) from the University of Western Ontario. He was a postdoctoral trainee for almost four years at University of Calgary and Harvard Medical School. He is an industry innovator having created the technology to produce lifelike synthetic platforms that can be used for the simulation of almost all cardiovascular reconstructive surgeries. He’s been heavily involved in the design and development of cardiovascular devices and technology for the past 10 years. He is currently an Assistant Professor with the University of British Colombia, Canada.",institutionString:"University of British Columbia",institution:{name:"University of British Columbia",country:{name:"Canada"}}},{id:"254463",title:"Prof.",name:"Haisheng",middleName:null,surname:"Yang",slug:"haisheng-yang",fullName:"Haisheng Yang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/254463/images/system/254463.jpeg",biography:"Haisheng Yang, Ph.D., Professor and Director of the Department of Biomedical Engineering, College of Life Science and Bioengineering, Beijing University of Technology. He received his Ph.D. degree in Mechanics/Biomechanics from Harbin Institute of Technology (jointly with University of California, Berkeley). Afterwards, he worked as a Postdoctoral Research Associate in the Purdue Musculoskeletal Biology and Mechanics Lab at the Department of Basic Medical Sciences, Purdue University, USA. He also conducted research in the Research Centre of Shriners Hospitals for Children-Canada at McGill University, Canada. Dr. Yang has over 10 years research experience in orthopaedic biomechanics and mechanobiology of bone adaptation and regeneration. He earned an award from Beijing Overseas Talents Aggregation program in 2017 and serves as Beijing Distinguished Professor.",institutionString:"Beijing University of Technology",institution:null},{id:"255757",title:"Dr.",name:"Igor",middleName:"Victorovich",surname:"Lakhno",slug:"igor-lakhno",fullName:"Igor Lakhno",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255757/images/system/255757.jpg",biography:"Lakhno Igor Victorovich was born in 1971 in Kharkiv (Ukraine). \nMD – 1994, Kharkiv National Medical Univesity.\nOb&Gyn; – 1997, master courses in Kharkiv Medical Academy of Postgraduate Education.\nPhD – 1999, Kharkiv National Medical Univesity.\nDSc – 2019, PL Shupik National Academy of Postgraduate Education \nLakhno Igor has been graduated from an international training courses on reproductive medicine and family planning held in Debrecen University (Hungary) in 1997. Since 1998 Lakhno Igor has worked as an associate professor of the department of obstetrics and gynecology of VN Karazin National University and an associate professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education. Since June 2019 he’s a professor of the department of obstetrics and gynecology of VN Karazin National University and a professor of the perinatology, obstetrics and gynecology department of Kharkiv Medical Academy of Postgraduate Education . He’s an author of about 200 printed works and there are 17 of them in Scopus or Web of Science databases. Lakhno Igor is a rewiever of Journal of Obstetrics and Gynaecology (Taylor and Francis), Informatics in Medicine Unlocked (Elsevier), The Journal of Obstetrics and Gynecology Research (Wiley), Endocrine, Metabolic & Immune Disorders-Drug Targets (Bentham Open), The Open Biomedical Engineering Journal (Bentham Open), etc. He’s defended a dissertation for DSc degree \\'Pre-eclampsia: prediction, prevention and treatment”. Lakhno Igor has participated as a speaker in several international conferences and congresses (International Conference on Biological Oscillations April 10th-14th 2016, Lancaster, UK, The 9th conference of the European Study Group on Cardiovascular Oscillations). His main scientific interests: obstetrics, women’s health, fetal medicine, cardiovascular medicine.",institutionString:"V.N. Karazin Kharkiv National University",institution:{name:"Kharkiv Medical Academy of Postgraduate Education",country:{name:"Ukraine"}}},{id:"89721",title:"Dr.",name:"Mehmet",middleName:"Cuneyt",surname:"Ozmen",slug:"mehmet-ozmen",fullName:"Mehmet Ozmen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/89721/images/7289_n.jpg",biography:null,institutionString:null,institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"243698",title:"M.D.",name:"Xiaogang",middleName:null,surname:"Wang",slug:"xiaogang-wang",fullName:"Xiaogang Wang",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/243698/images/system/243698.png",biography:"Dr. Xiaogang Wang, a faculty member of Shanxi Eye Hospital specializing in the treatment of cataract and retinal disease and a tutor for postgraduate students of Shanxi Medical University, worked in the COOL Lab as an international visiting scholar under the supervision of Dr. David Huang and Yali Jia from October 2012 through November 2013. Dr. Wang earned an MD from Shanxi Medical University and a Ph.D. from Shanghai Jiao Tong University. Dr. Wang was awarded two research project grants focused on multimodal optical coherence tomography imaging and deep learning in cataract and retinal disease, from the National Natural Science Foundation of China. He has published around 30 peer-reviewed journal papers and four book chapters and co-edited one book.",institutionString:"Shanxi Eye Hospital",institution:{name:"Shanxi Eye Hospital",country:{name:"China"}}},{id:"242893",title:"Ph.D. Student",name:"Joaquim",middleName:null,surname:"De Moura",slug:"joaquim-de-moura",fullName:"Joaquim De Moura",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/242893/images/7133_n.jpg",biography:"Joaquim de Moura received his degree in Computer Engineering in 2014 from the University of A Coruña (Spain). In 2016, he received his M.Sc degree in Computer Engineering from the same university. He is currently pursuing his Ph.D degree in Computer Science in a collaborative project between ophthalmology centers in Galicia and the University of A Coruña. His research interests include computer vision, machine learning algorithms and analysis and medical imaging processing of various kinds.",institutionString:null,institution:{name:"University of A Coruña",country:{name:"Spain"}}},{id:"267434",title:"Dr.",name:"Rohit",middleName:null,surname:"Raja",slug:"rohit-raja",fullName:"Rohit Raja",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRZkkQAG/Profile_Picture_2022-05-09T12:55:18.jpg",biography:null,institutionString:null,institution:null},{id:"294334",title:"B.Sc.",name:"Marc",middleName:null,surname:"Bruggeman",slug:"marc-bruggeman",fullName:"Marc Bruggeman",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/294334/images/8242_n.jpg",biography:"Chemical engineer graduate, with a passion for material science and specific interest in polymers - their near infinite applications intrigue me. \n\nI plan to continue my scientific career in the field of polymeric biomaterials as I am fascinated by intelligent, bioactive and biomimetic materials for use in both consumer and medical applications.",institutionString:null,institution:null},{id:"244950",title:"Dr.",name:"Salvatore",middleName:null,surname:"Di Lauro",slug:"salvatore-di-lauro",fullName:"Salvatore Di Lauro",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0030O00002bSF1HQAW/ProfilePicture%202021-12-20%2014%3A54%3A14.482",biography:"Name:\n\tSALVATORE DI LAURO\nAddress:\n\tHospital Clínico Universitario Valladolid\nAvda Ramón y Cajal 3\n47005, Valladolid\nSpain\nPhone number: \nFax\nE-mail:\n\t+34 983420000 ext 292\n+34 983420084\nsadilauro@live.it\nDate and place of Birth:\nID Number\nMedical Licence \nLanguages\t09-05-1985. Villaricca (Italy)\n\nY1281863H\n474707061\nItalian (native language)\nSpanish (read, written, spoken)\nEnglish (read, written, spoken)\nPortuguese (read, spoken)\nFrench (read)\n\t\t\nCurrent position (title and company)\tDate (Year)\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. Private practise.\t2017-today\n\n2019-today\n\t\n\t\nEducation (High school, university and postgraduate training > 3 months)\tDate (Year)\nDegree in Medicine and Surgery. University of Neaples 'Federico II”\nResident in Opthalmology. Hospital Clinico Universitario Valladolid\nMaster in Vitreo-Retina. IOBA. University of Valladolid\nFellow of the European Board of Ophthalmology. Paris\nMaster in Research in Ophthalmology. University of Valladolid\t2003-2009\n2012-2016\n2016-2017\n2016\n2012-2013\n\t\nEmployments (company and positions)\tDate (Year)\nResident in Ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl.\nFellow in Vitreo-Retina. IOBA. University of Valladolid\nVitreo-Retinal consultant in ophthalmology. Hospital Clinico Universitario Valladolid. Sacyl. National Health System.\nVitreo-Retinal consultant in ophthalmology. Instituto Oftalmologico Recoletas. Red Hospitalaria Recoletas. \n\t2012-2016\n2016-2017\n2017-today\n\n2019-Today\n\n\n\t\nClinical Research Experience (tasks and role)\tDate (Year)\nAssociated investigator\n\n' FIS PI20/00740: DESARROLLO DE UNA CALCULADORA DE RIESGO DE\nAPARICION DE RETINOPATIA DIABETICA BASADA EN TECNICAS DE IMAGEN MULTIMODAL EN PACIENTES DIABETICOS TIPO 1. Grant by: Ministerio de Ciencia e Innovacion \n\n' (BIO/VA23/14) Estudio clínico multicéntrico y prospectivo para validar dos\nbiomarcadores ubicados en los genes p53 y MDM2 en la predicción de los resultados funcionales de la cirugía del desprendimiento de retina regmatógeno. Grant by: Gerencia Regional de Salud de la Junta de Castilla y León.\n' Estudio multicéntrico, aleatorizado, con enmascaramiento doble, en 2 grupos\nparalelos y de 52 semanas de duración para comparar la eficacia, seguridad e inmunogenicidad de SOK583A1 respecto a Eylea® en pacientes con degeneración macular neovascular asociada a la edad' (CSOK583A12301; N.EUDRA: 2019-004838-41; FASE III). Grant by Hexal AG\n\n' Estudio de fase III, aleatorizado, doble ciego, con grupos paralelos, multicéntrico para comparar la eficacia y la seguridad de QL1205 frente a Lucentis® en pacientes con degeneración macular neovascular asociada a la edad. (EUDRACT: 2018-004486-13). Grant by Qilu Pharmaceutical Co\n\n' Estudio NEUTON: Ensayo clinico en fase IV para evaluar la eficacia de aflibercept en pacientes Naive con Edema MacUlar secundario a Oclusion de Vena CenTral de la Retina (OVCR) en regimen de tratamientO iNdividualizado Treat and Extend (TAE)”, (2014-000975-21). Grant by Fundacion Retinaplus\n\n' Evaluación de la seguridad y bioactividad de anillos de tensión capsular en conejo. Proyecto Procusens. Grant by AJL, S.A.\n\n'Estudio epidemiológico, prospectivo, multicéntrico y abierto\\npara valorar la frecuencia de la conjuntivitis adenovírica diagnosticada mediante el test AdenoPlus®\\nTest en pacientes enfermos de conjuntivitis aguda”\\n. National, multicenter study. Grant by: NICOX.\n\nEuropean multicentric trial: 'Evaluation of clinical outcomes following the use of Systane Hydration in patients with dry eye”. Study Phase 4. Grant by: Alcon Labs'\n\nVLPs Injection and Activation in a Rabbit Model of Uveal Melanoma. Grant by Aura Bioscience\n\nUpdating and characterization of a rabbit model of uveal melanoma. Grant by Aura Bioscience\n\nEnsayo clínico en fase IV para evaluar las variantes genéticas de la vía del VEGF como biomarcadores de eficacia del tratamiento con aflibercept en pacientes con degeneración macular asociada a la edad (DMAE) neovascular. Estudio BIOIMAGE. IMO-AFLI-2013-01\n\nEstudio In-Eye:Ensayo clínico en fase IV, abierto, aleatorizado, de 2 brazos,\nmulticçentrico y de 12 meses de duración, para evaluar la eficacia y seguridad de un régimen de PRN flexible individualizado de 'esperar y extender' versus un régimen PRN según criterios de estabilización mediante evaluaciones mensuales de inyecciones intravítreas de ranibizumab 0,5 mg en pacientes naive con neovascularización coriodea secunaria a la degeneración macular relacionada con la edad. CP: CRFB002AES03T\n\nTREND: Estudio Fase IIIb multicéntrico, randomizado, de 12 meses de\nseguimiento con evaluador de la agudeza visual enmascarado, para evaluar la eficacia y la seguridad de ranibizumab 0.5mg en un régimen de tratar y extender comparado con un régimen mensual, en pacientes con degeneración macular neovascular asociada a la edad. CP: CRFB002A2411 Código Eudra CT:\n2013-002626-23\n\n\n\nPublications\t\n\n2021\n\n\n\n\n2015\n\n\n\n\n2021\n\n\n\n\n\n2021\n\n\n\n\n2015\n\n\n\n\n2015\n\n\n2014\n\n\n\n\n2015-16\n\n\n\n2015\n\n\n2014\n\n\n2014\n\n\n\n\n2014\n\n\n\n\n\n\n\n2014\n\nJose Carlos Pastor; Jimena Rojas; Salvador Pastor-Idoate; Salvatore Di Lauro; Lucia Gonzalez-Buendia; Santiago Delgado-Tirado. Proliferative vitreoretinopathy: A new concept of disease pathogenesis and practical\nconsequences. Progress in Retinal and Eye Research. 51, pp. 125 - 155. 03/2016. DOI: 10.1016/j.preteyeres.2015.07.005\n\n\nLabrador-Velandia S; Alonso-Alonso ML; Di Lauro S; García-Gutierrez MT; Srivastava GK; Pastor JC; Fernandez-Bueno I. Mesenchymal stem cells provide paracrine neuroprotective resources that delay degeneration of co-cultured organotypic neuroretinal cultures.Experimental Eye Research. 185, 17/05/2019. DOI: 10.1016/j.exer.2019.05.011\n\nSalvatore Di Lauro; Maria Teresa Garcia Gutierrez; Ivan Fernandez Bueno. Quantification of pigment epithelium-derived factor (PEDF) in an ex vivo coculture of retinal pigment epithelium cells and neuroretina.\nJournal of Allbiosolution. 2019. ISSN 2605-3535\n\nSonia Labrador Velandia; Salvatore Di Lauro; Alonso-Alonso ML; Tabera Bartolomé S; Srivastava GK; Pastor JC; Fernandez-Bueno I. Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits. Graefe's archive for clinical and experimental ophthalmology. 256 - 1, pp. 125 - 134. 01/2018. DOI: 10.1007/s00417-017-3842-3\n\n\nSalvatore Di Lauro, David Rodriguez-Crespo, Manuel J Gayoso, Maria T Garcia-Gutierrez, J Carlos Pastor, Girish K Srivastava, Ivan Fernandez-Bueno. A novel coculture model of porcine central neuroretina explants and retinal pigment epithelium cells. Molecular Vision. 2016 - 22, pp. 243 - 253. 01/2016.\n\nSalvatore Di Lauro. Classifications for Proliferative Vitreoretinopathy ({PVR}): An Analysis of Their Use in Publications over the Last 15 Years. Journal of Ophthalmology. 2016, pp. 1 - 6. 01/2016. DOI: 10.1155/2016/7807596\n\nSalvatore Di Lauro; Rosa Maria Coco; Rosa Maria Sanabria; Enrique Rodriguez de la Rua; Jose Carlos Pastor. Loss of Visual Acuity after Successful Surgery for Macula-On Rhegmatogenous Retinal Detachment in a Prospective Multicentre Study. Journal of Ophthalmology. 2015:821864, 2015. DOI: 10.1155/2015/821864\n\nIvan Fernandez-Bueno; Salvatore Di Lauro; Ivan Alvarez; Jose Carlos Lopez; Maria Teresa Garcia-Gutierrez; Itziar Fernandez; Eva Larra; Jose Carlos Pastor. Safety and Biocompatibility of a New High-Density Polyethylene-Based\nSpherical Integrated Porous Orbital Implant: An Experimental Study in Rabbits. Journal of Ophthalmology. 2015:904096, 2015. DOI: 10.1155/2015/904096\n\nPastor JC; Pastor-Idoate S; Rodríguez-Hernandez I; Rojas J; Fernandez I; Gonzalez-Buendia L; Di Lauro S; Gonzalez-Sarmiento R. Genetics of PVR and RD. Ophthalmologica. 232 - Suppl 1, pp. 28 - 29. 2014\n\nRodriguez-Crespo D; Di Lauro S; Singh AK; Garcia-Gutierrez MT; Garrosa M; Pastor JC; Fernandez-Bueno I; Srivastava GK. Triple-layered mixed co-culture model of RPE cells with neuroretina for evaluating the neuroprotective effects of adipose-MSCs. Cell Tissue Res. 358 - 3, pp. 705 - 716. 2014.\nDOI: 10.1007/s00441-014-1987-5\n\nCarlo De Werra; Salvatore Condurro; Salvatore Tramontano; Mario Perone; Ivana Donzelli; Salvatore Di Lauro; Massimo Di Giuseppe; Rosa Di Micco; Annalisa Pascariello; Antonio Pastore; Giorgio Diamantis; Giuseppe Galloro. Hydatid disease of the liver: thirty years of surgical experience.Chirurgia italiana. 59 - 5, pp. 611 - 636.\n(Italia): 2007. ISSN 0009-4773\n\nChapters in books\n\t\n' Salvador Pastor Idoate; Salvatore Di Lauro; Jose Carlos Pastor Jimeno. PVR: Pathogenesis, Histopathology and Classification. Proliferative Vitreoretinopathy with Small Gauge Vitrectomy. Springer, 2018. ISBN 978-3-319-78445-8\nDOI: 10.1007/978-3-319-78446-5_2. \n\n' Salvatore Di Lauro; Maria Isabel Lopez Galvez. Quistes vítreos en una mujer joven. Problemas diagnósticos en patología retinocoroidea. Sociedad Española de Retina-Vitreo. 2018.\n\n' Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor Jimeno. iOCT in PVR management. OCT Applications in Opthalmology. pp. 1 - 8. INTECH, 2018. DOI: 10.5772/intechopen.78774.\n\n' Rosa Coco Martin; Salvatore Di Lauro; Salvador Pastor Idoate; Jose Carlos Pastor. amponadores, manipuladores y tinciones en la cirugía del traumatismo ocular.Trauma Ocular. Ponencia de la SEO 2018..\n\n' LOPEZ GALVEZ; DI LAURO; CRESPO. OCT angiografia y complicaciones retinianas de la diabetes. PONENCIA SEO 2021, CAPITULO 20. (España): 2021.\n\n' Múltiples desprendimientos neurosensoriales bilaterales en paciente joven. Enfermedades Degenerativas De Retina Y Coroides. SERV 04/2016. \n' González-Buendía L; Di Lauro S; Pastor-Idoate S; Pastor Jimeno JC. Vitreorretinopatía proliferante (VRP) e inflamación: LA INFLAMACIÓN in «INMUNOMODULADORES Y ANTIINFLAMATORIOS: MÁS ALLÁ DE LOS CORTICOIDES. RELACION DE PONENCIAS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGIA. 10/2014.",institutionString:null,institution:null},{id:"265335",title:"Mr.",name:"Stefan",middleName:"Radnev",surname:"Stefanov",slug:"stefan-stefanov",fullName:"Stefan Stefanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/265335/images/7562_n.jpg",biography:null,institutionString:null,institution:null},{id:"318905",title:"Prof.",name:"Elvis",middleName:"Kwason",surname:"Tiburu",slug:"elvis-tiburu",fullName:"Elvis Tiburu",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Ghana",country:{name:"Ghana"}}},{id:"336193",title:"Dr.",name:"Abdullah",middleName:null,surname:"Alamoudi",slug:"abdullah-alamoudi",fullName:"Abdullah Alamoudi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Majmaah University",country:{name:"Saudi Arabia"}}},{id:"318657",title:"MSc.",name:"Isabell",middleName:null,surname:"Steuding",slug:"isabell-steuding",fullName:"Isabell Steuding",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"318656",title:"BSc.",name:"Peter",middleName:null,surname:"Kußmann",slug:"peter-kussmann",fullName:"Peter Kußmann",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Harz University of Applied Sciences",country:{name:"Germany"}}},{id:"338222",title:"Mrs.",name:"María José",middleName:null,surname:"Lucía Mudas",slug:"maria-jose-lucia-mudas",fullName:"María José Lucía Mudas",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Carlos III University of Madrid",country:{name:"Spain"}}},{id:"147824",title:"Mr.",name:"Pablo",middleName:null,surname:"Revuelta Sanz",slug:"pablo-revuelta-sanz",fullName:"Pablo Revuelta Sanz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Carlos III University of Madrid",country:{name:"Spain"}}}]}},subseries:{item:{id:"39",type:"subseries",title:"Environmental Resilience and Management",keywords:"Anthropic effects, Overexploitation, Biodiversity loss, Degradation, Inadequate Management, SDGs adequate practices",scope:"\r\n\tThe environment is subject to severe anthropic effects. Among them are those associated with pollution, resource extraction and overexploitation, loss of biodiversity, soil degradation, disorderly land occupation and planning, and many others. These anthropic effects could potentially be caused by any inadequate management of the environment. However, ecosystems have a resilience that makes them react to disturbances which mitigate the negative effects. It is critical to understand how ecosystems, natural and anthropized, including urban environments, respond to actions that have a negative influence and how they are managed. It is also important to establish when the limits marked by the resilience and the breaking point are achieved and when no return is possible. The main focus for the chapters is to cover the subjects such as understanding how the environment resilience works, the mechanisms involved, and how to manage them in order to improve our interactions with the environment and promote the use of adequate management practices such as those outlined in the United Nations’ Sustainable Development Goals.
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