Open access peer-reviewed Edited Volume

Sudden Cardiac Death

Peter Magnusson

Karolinska Institute



Incidence Epidemiology Risk Assessment Treatment Coronary Artery Disease Ion-channel Disease Cardiomyopathy Myocardial Infarction Resynchronization Medication Implantable Cardioverter Defibrillator Subcutaneous ICD

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About the book

Sudden cardiac death (SCD) is a life-threatening cardiac condition, typically related to an arrhythmia that results in circulatory collapse and may cause death in minutes. In the United States, SCD is the third leading cause of death with about 300,000 to 400,000 deaths a year. As the name suggests, SCD may occur without warning in a patient without symptoms. When it occurs in an out-of-hospital setting, many victims die before help arrives. Although it is more typical in people over age 60, SCD may occur in young people, even teenagers. For about 50% of cases, SCD is the first symptom of heart disease. About a quarter of all cardiac-related deaths a year may be traced back to SCD.

SCD represents a global threat to health and one for which we have only partial answers. With growing elucidation of the underlying pathophysiological mechanisms of SCD, better patient identification and treatment options are being developed. The European Heart Journal has issued its 2015 guidelines for preventing SCD with recommendations in many cases for implantable cardioverter defibrillators but the costs and associated risks of device implantation are such that patients must be stratified for risk. Risk stratification paradigms are emerging and show that certain cardiac conditions (acute myocardial infarction, structural heart disease, heart failure) increase risk. More recent studies have found a prognostic role for short episodes of early ventricular tachycardia.1 Genetics may predispose certain individuals toward SCD, with the best known of these syndromes Long QT and Brugada. In addition to ICD therapy, pharmacological options, ablative procedures, and other treatments may be appropriate.

The book may cover aspects such as: Epidemiology, Risk Stratification, Primary and Secondary Prevention for Device Therapy, The Prognostic Role of Early Non-sustained Ventricular Tachycardia, SCD in Acute Coronary Syndrome following Myocardial Infarction, SCD in Hypertrophic Cardiomyopathy, SCD Arrhytmogenic Right Ventricular Cardiomyopathy, SCD in Heart Failure, Atherosclerosis and Ischemia in SCD, Genetic Causes of SCD (Long QT, Brugada), SCD in Athletes, Arrhythmogenesis and SCD (Channelopathies), A Short History of ICD Therapy, ICDs: Risk and Benefits, Cost-Effectiveness of ICD Therapy, Subcutaneous ICDs, Automatic External Defibrillators, Wearable Defibrillators, Pharmacological Therapy (Anti-Arrhythmic Agents), Patient Management Issues, Mental Health Conditions and SCD Survival, and ICDs at End of Patient Life.

You are welcome to contribute. Together we can fight sudden cardiac death!

Publishing process

Book initiated and editor appointed

Date completed: October 23rd 2019

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: January 12th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 1st 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: May 31st 2020

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About the editor

Peter Magnusson

Karolinska Institute

Peter Magnusson is a senior consultant in cardiology and active in research projects in arrhythmia, cardiomyopathy, heart failure, and valvular disease. He is affiliated with the Karolinska Institute, Sweden, and the Center for Research and Development, Gävleborg, at Uppsala University, Sweden. Dr. Magnusson\'s research involves epidemiological studies, qualitative methods, observational studies, and randomized controlled trials. He is passionate about teaching and supervision, especially in academic projects. Currently, he is striving for implementation of research findings in the healthcare system.

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Book chapters authored 5

Books edited 2

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