About the book
The Chikungunya virus (CHIKV) is an RNA virus that is transmitted to humans by Aedes mosquitos, a type of arthropod commonly occurring in tropical and subtropical countries worldwide. In humans, CHIKV causes an infection in which symptoms are similar to those of the Dengue and the Zika disease which are also transmitted to humans by the same type of mosquitos. Needless to say, that a health professional has to be extremely well trained to draw a distinction between CHIKV infection and Dengue and/or Zika infection. Even then, a molecular diagnosis is necessary to draw an accurate conclusion as to the disease a patient is infected with. The past decade has been marked by not only multiple outbreaks of Chikungunya in endemic tropical and subtropical countries and sometimes beyond, but also by major findings of unanticipated health complications caused by CHIKV infection in a patient. This includes for instance the development of neurologic complications in many Brazilian cases.
The purpose of this book is to dive into the history of the disease, the molecular characterization of the virus, the diagnosis, the molecular mechanisms of CHIKV pathogenesis, the epidemiology of the disease, and the prevention and treatment. This book is intended to be a reference book on Chikungunya for graduate students, researchers, faculty, and health professionals. It will bring new insights on the multiple facets of the disease to the scientific and academic communities that are both in need to have a tool that will contain the most recent findings and advances that could be used as a trampoline to further the fight against Chikungunya.