Open access peer-reviewed Edited Volume


Current Issues in Diagnosis and Management


Mayank Vats

Rashid Hospital

Data are rapidly accumulating from all over the world regarding the efficacy of standardized treatment regimens for drug-sensitive, drug-resistant TB and latent TB infection. While we are facing the menace of multi drug-resistant TB [MDR-TB], extensively drug-resistant tuberculosis [XDR­ TB] has emerged threatening to undermine global efforts at TB control. Hence we have included chapters to cover all aspects of the diagnosis and management of MDR TB. This book will cover all these developments in great detail. With the widespread availability of internet globally various standard web resources available on TB have also been included so that the readers may get the comprehensive and updated guidelines from these resources. The changing clinical presentation of TB, advances in laboratory, imaging diagnostic modalities, therapeutic measures and emergence of MDR TB all suggest a pressing need to have a updated book on TB. Furthermore, while all physicians encounter the TB disease in their clinical practice, there have been a lot of controversies and misconceptions over various issues for the diagnosis and management of TB. Paucity of a well referenced, updated, standard book of TB has prompted us to undertake this venture sharing the clinical experience of global experts of TB. Our book contains chapters on epidemiology, immune-pathology, diagnosis, treatment and latest advances for TB, highlighting the global perspective of tuberculosis. World-wide resurgence of MDR TB indicates that the battle against this foe of mankind will continue in the coming years. TB still remains to be a research priority of paramount importance from medical, social and financial aspects and we have attempted to highlight all the aspects for the treatment of TB. We believe that this book will serve as a practical guide for the diagnosis and management of TB for practicing physicians (especially pulmonologists and internists) and all those who are involved in the management of TB.

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TuberculosisCurrent Issues in Diagnosis and ManagementEdited by Bassam Mahboub

Published: March 20th 2013

DOI: 10.5772/56396

ISBN: 978-953-51-1049-1

eBook (PDF) ISBN: 978-953-51-7117-1

Copyright year: 2013

Books open for chapter submissions

70771 Total Chapter Downloads

39 Crossref Citations

40 Web of Science Citations

78 Dimensions Citations


Open access peer-reviewed

1. Mycobacterium tuberculosis Adaptation to Survival in a Human Host

By Beatrice Saviola


Open access peer-reviewed

2. The Immune Response to Mycobacterium tuberculosis Infection in Humans

By Zeev Theodor Handzel


Open access peer-reviewed

3. Lipid Inclusions in Mycobacterial Infections

By Matthias Stehr, Ayssar A. Elamin and Mahavir Singh


Open access peer-reviewed

4. The Role of Antibodies in the Defense Against Tuberculosis

By Armando Acosta, Yamile Lopez, Norazmi Mohd Nor, Rogelio Hernández Pando, Nadine Alvarez, Maria Elena Sarmiento and Aharona Glatman-Freedman


Open access peer-reviewed

5. Influence of the Interferon–Gamma (IFN–γ) and Tumor Necrosis Factor Alpha (TNF–α) Gene Polymorphisms in TB Occurrence and Clinical Spectrum

By Márcia Quinhones Pires Lopes, Raquel Lima de Figueiredo Teixeira, Antonio Basilio de Miranda, Rafael Santos Pinto, Lizânia Borges Spinassé, Fernanda Carvalho Queiroz Mello, José Roberto Lapa e Silva, Philip Noel Suffys and Adalberto Rezende Santos


Open access peer-reviewed

6. Tuberculosis Pharmacogenetics: State of The Art

By Raquel Lima de Figueiredo Teixeira, Márcia Quinhones Pires Lopes, Philip Noel Suffys and Adalberto Rezende Santos


Open access peer-reviewed

7. Pathophysiology of Tuberculosis

By Ruiru Shi and Isamu Sugawara


Open access peer-reviewed

8. Laboratory Diagnosis of Tuberculosis - Latest Diagnostic Tools

By Gunes Senol


Open access peer-reviewed

9. Diagnostic Evaluation of Tuberculosis

By Mochammad Hatta and A. R. Sultan


Open access peer-reviewed

10. First– and Second–Line Drugs and Drug Resistance

By Hum Nath Jnawali and Sungweon Ryoo


Open access peer-reviewed

11. Epidemiology of Multidrug Resistant Tuberculosis (MDR-TB)

By Dhammika Nayoma Magana-Arachchi


Open access peer-reviewed

12. Management of Drug-Resistant TB

By Zakaria Hmama


Open access peer-reviewed

13. Drug-Resistant Tuberculosis – Diagnosis, Treatment, Management and Control: The Experience in Thailand

By Attapon Cheepsattayakorn


Open access peer-reviewed

14. Tuberculous Pleural Effusion

By Wolfgang Frank


Open access peer-reviewed

15. Neurotuberculosis and HIV Infection

By Simona Alexandra Iacob and Diana Gabriela Iacob


Open access peer-reviewed

16. Research and Development of New Drugs Against Tuberculosis

By Juan D. Guzman, Ximena Montes-Rincón and Wellman Ribón


Open access peer-reviewed

17. Web Resources on TB: Information, Research, and Data Analysis

By Marcos Catanho and Antonio Basílio de Miranda


Open access peer-reviewed

18. Peadiatric Tuberculosis: Is the World Doing Enough?

By Claude Kirimuhuzya


Open access peer-reviewed

19. Economic Evaluation of Diagnosis Tuberculosis in Hospital Setting

By Luciene C. Scherer


Open access peer-reviewed

20. Pulmonary Tuberculosis in Latin America: Patchwork Studies Reveal Inequalities in Its Control – The Cases of Chiapas (Mexico), Chine (Ecuador) and Lima (Peru)

By Héctor Javier Sánchez-Pérez, Olivia Horna–Campos, Natalia Romero-Sandoval, Ezequiel Consiglio and Miguel Martín Mateo


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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