About the book
Congenital anomalies constitute a major component of the significant diseases encountered in newborn infants. Approximately 2-3% of all neonates born in the USA suffer from some form of a major or minor congenital defect. Birth defects are responsible for about 300000 annual neonatal deaths worldwide and a significant number of children born with congenital defects suffer from chronic morbidities and disabilities in later life, which may adversely affect their quality of life and substantially limit their productivity. Birth defects begin during intrauterine life and may be triggered by a variety of preventable and non-preventable etiological factors. In certain conditions of preventable birth defects management may start even before conception. Advances in perinatal care and diagnostic testing such as amniocentesis and chorionic villus sampling, have made earlier detection of genetically determined congenital abnormalities possible. Furthermore, rapid progress in the postnatal management of various genetic defects, organ system anomalies and metabolic disorders have almost eliminated certain complications that were assessed as fatal previously.
This book will aim to examine the clinical aspects and current perspectives in the etiopathogenesis, diagnosis, prevention, and treatment of congenital anomalies in the neonates.