Open access peer-reviewed Edited Volume

Mosquito Research - Recent Advances in Pathogen Interactions, Immunity, and Vector Control Strategies

Henry Puerta-Guardo

Autonomous University of Yucatán

An enthusiastic young research expert in viral pathogenesis and human-to-mosquito-transmitted diseases. Research assistant at the Universidad Autonoma de Yucatan in Merida, Mexico. Member of the American Society for Virology, Mexican Society for Virology, and Glycobiology


Pablo Manrique-Saide

Autonomous University of Yucatán


Pathogens Virus Parasite Protective Barriers Immune System Arthropod-Borne Diseases Emerging Diseases Distribution Abundance Behavior Vector Control Biological Control

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About the book

Mosquitoes (Order: Diptera, Family: Culicidae) are important organisms for study, both as vectors of human disease and the study of biological systems. Today, more than 3,000 species of mosquitoes have been described worldwide, and beyond the nuisance factor, most of these are carriers, or vectors, for some of the most important human emerging-and-re-emerging mosquito-borne diseases (MBDs) such as dengue, Zika, chikungunya, yellow fever, and malaria that together kills around 0·6–1·2 million people a year and put at risk of infection more than 80% of the population worldwide.

In recent years, increasing evidence shows that the emergence of MBDs is determined by a complex set of demographics, environmental and social factors, along with increased mosquito susceptibility to new pathogens resulting in increased transmission to human populations, rapid adaptation to new environmental conditions and landscapes, having significant consequences into mosquito population dynamics as well as disease transmission.

Growing progress has been made on better understanding the interactions between mosquitoes and human-transmissible pathogens, their protective responses against invasive pathogens, the dynamics that lead to their environmental adaptation, and the potential strategies for hindering it. Despite this, today, there is not a single intervention likely to stop most MBDs. Very effective vector control measures such as the Integrated Vector Management (IVM) including environmental management, biological control, and chemical control among others are suitable strategies that may achieve the greatest disease control benefit most cost-effectively while minimizing negative impacts on ecosystems. However, mosquitoes continue to be the deadliest animals on Earth and the public enemy number one in the fight against global infectious diseases.

In this book, we will address over five distinctly but intimately related sections to describe the recent advances (i) in mosquito-pathogen interactions leading to host infection, (ii) its immune responses, (iii) MBDs transmission into human populations, (iv) and vector adaptation under actual global climate conditions and human demographic dynamics, which impact (v) the development of new vector control strategies as well as improvement of the existing vector control techniques, leading to preventable strategies for reducing human-transmissible mosquito-borne diseases.

Publishing process

Book initiated and editor appointed

Date completed: November 2nd 2021

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: January 29th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: April 19th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: June 18th 2022

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Henry Puerta-Guardo

Autonomous University of Yucatán

my hometown is Cartagena de Indias in Colombia (South America). In 2004, I finished my university studies and graduated as a bacteriologist at the University of San Buenaventura (Cartagena). Then, I moved to Venezuela where I was granted an international scholarship that supported my master studies in Cellular Biology and Microbiology at the Venezuelan Institute of Scientific Research (IVIC). After that, I traveled to Mexico where I got my doctorate degree in Virology (Infectomics) at the CINVESTAV-IPN again thanks to the financial support granted by CONACYT-Mexico. Since my master's studies, I have been working on arbovirus pathogenesis trying to elucidate the molecular and cellular mechanisms triggered by host innate and humoral responses against flavivirus infections including DENV and ZIKV. Because of this, I did six intensive years of training as a post-doctoral fellow at the division of infectious diseases and vaccinology of the University of California at Berkeley, where I discovered that the non-structural protein 1 of distinct flavivirus represent a critical viral factor that contributes to viral pathogenesis and potentially disease. Right now, I'm still connected to the UC Berkeley team and also I joined an incredible multidisciplinary team of entomologists, sociologists, physicians, and nurses among others at the Universidad Autónoma de Yucatán in Mérida, Mexico, and the University of Emory at Georgia, where I work and learn about the dynamics of mosquito transmitted viruses and vector control strategies.

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