Open access peer-reviewed Edited Volume

Crohn’s disease – Recent Advances

Monjur Ahmed

Thomas Jefferson University

Practicing gastroenterologist for more than 20 years. Dr. Ahmed is affiliated with Thomas Jefferson University Hospitals and Jefferson Methodist Hospital, USA. Special interest in eosinophilic esophagitis, gastrointestinal motility, and dysphagia.


Incidence Prevalence Pathogenesis Immunology of Crohn’s Disease Clinical Picture Clinical Aspects Lab Tests Serology in Crohn’s Disease Immunomodulators Biologic Agents Endoscopy Serology in Crohn’s Disease

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About the book

Crohn’s disease is a chronic inflammatory disease that can affect the gastrointestinal tract from the mouth to the anus. The exact etiology is unknown. The incidence is about 10.7 cases per 100,000 people in the United States. The disease is not only inflammatory in nature in the gastrointestinal tract but also can cause stricture, fistula, malignancy and extra-intestinal manifestations. The natural course of the disease is relapse and remission. As it affects the mostly young population, their life can be debilitating if the disease activity is not under control. There are various laboratory, imaging and endoscopic studies available to diagnose Crohn’s disease and follow up after treatment. The goal of treatment is not only clinical and endoscopic remission but also mucosal healing. There are various treatments available at the present time for Crohn’s disease. But treatment options are not optimal considering the efficacy rate and side effect profile. As a result, many clinical trials are ongoing for better control of Crohn’s disease. Many biologic agents are in the pipeline to be released into the market. When medical therapy fails, surgical intervention is done. Fortunately, the surgery rate in Crohn’s disease is decreasing.

This book will focus on the epidemiology, pathophysiology, different clinical aspects, appropriate investigations and current management strategy of Crohn’s disease.

Publishing process

Book initiated and editor appointed

Date completed: July 3rd 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: September 22nd 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: December 11th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: February 9th 2021

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About the editor

Monjur Ahmed

Thomas Jefferson University

Working as an Associate Professor of Medicine at Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Practicing gastroenterologist for 20 years. Special interest in eosinophilic esophagitis, gastrointestinal motility and dysphagia. He also serves as an Editor-in-Chief of World Journal of Gastrointestinal Oncology.

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Book chapters authored 4

Books edited 1

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As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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