About the book
Colorectal cancer is one of the most common tumors in the adult population. Since the adenocarcinoma sequence was described in the 1970s, the molecular mechanisms involved in the pathogenesis of colorectal cancer have been studied. The study of colorectal cancer is one of the most important in understanding of the mechanisms involved in the development of malignant neoplasms. Several genes, such as RAS, BRAF, PARP, and TP53, have been well identified as participants in carcinogenesis. Also, increasing advances in molecular biology studies are contributing significantly to the understanding of colorectal cancer progression, enabling early detection of premalignant lesions, expanding the possibilities of appropriate diagnosis and prognosis prediction, and further developing efficient therapies. Here, the necessity is raised to construct an up-to-date understanding of this information, which has been established and organized from the past. Accordingly, this book intends to cover a wide range of clinical and non-clinical research topics related to the pathogenesis, diagnosis and prognosis prediction of colorectal cancer, as well as recent therapeutic options.
