About the book
Norovirus (also called the "winter vomiting bug") is the most common cause of gastroenteritis with clinical symptoms of diarrhea, vomiting, stomach pain and headache. Dehydration is the main risk and complication of norovirus.
A person usually develops symptoms 12 to 48 hours after being exposed to virus.
Norovirus causes 785 million cases of acute gastroenteritis, making it the most common cause of acute gastroenteritis worldwide. Disease more commonly occurs in winter months causing infections in both developed and developing countries.
It is usually not fatal, but the illness can be serious for infants and the elderly (about 200000 per year).
Those under the age of five are most often affected and in this group it results in about 50.000 deaths in the developing world.
It is highly contagious and it can be transmitted both directly from person to person (in 62-84 % in all reported outbreaks) and indirectly via contaminated water and food. Home, schools, restaurants, and other more commonly used places have important role in spreading the virus.
The Noroviruses (NoV) are in general diverse group of single-stranded positive-sense RNA, non-enveloped viruses (International Committee on Taxonomy of Viruses made different classifications in this field). Different serotypes, strains and isolates are found in infected patients. The diagnosis can be obtained by the observations based on the clinical pictures, PCR assays or quantitative PCR assays. The ELISA test can be applied for identifications of different strains of Noroviruses.
The Centres for Disease Control and Prevention (CDC) printed a guideline addressing strategies for the prevention and control of norovirus gastroenteritis (2011) which were organized into 12 categories.
This book will be a self-contained collection of scholarly papers which provide updates on Norovirus diagnostics, treatments and prevention targeting an audience of practicing researchers, academics, Ph.D. students and other scientists.