Open access peer-reviewed Edited Volume

Capsaicin and its Human Therapeutic Development

Edited by Gyula Mozsik

University of Pécs

The enormous field of this topic is clearly shown by the following facts: during the last ten years (2007-2016) around 500 papers/ year and 523 review articles are listed in the PubMed database on capsaicin, and over 200/year are under keywords of "capsaicin human". Recently, two major studies on the mortality of consumers of spicy food containing capsaicin and nonconsumers (over 350000 men and women aged 30-79 with heart disease, cancer, and stroke at baseline over 3.5 million person-years, 2004-2013) showed that the relative risk in total mortality was reduced by 14% in 10 diverse geographic areas of China (2015). Similarly, in the USA, (16,179 participants during over 2,70,000 person/year with the median of 18.9 years) the total mortality was reduced by 13% in populations consuming hot chili (2017). Recently, the book series "Progress in Drug Research" the 68th volume dealt for the first time on "Capsaicin as a Therapeutic Molecule" (Springer, Basel, 2014). Five excellent chapters are found in this book dealing with procedures of capsaicin from capsicum plants, emerging technologies to improve capsaicin delivery, capsaicinoid diversity and its human food preference, capsaicin and lipid metabolism, and predictors in treatment response to capsaicin. The results of these observations clearly indicate that the capsaicin research has changed direction to include human medical treatment with capsaicin. The book gathers knowledge from experts in basic and clinical sciences, pharmacologists, in the nutrition and food industry, in the drug industry, technologists, plant cultivators, as well as experts across a wide scale of medical branches.

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Capsaicin and its Human Therapeutic DevelopmentEdited by Gyula Mozsik

Published: August 1st 2018

DOI: 10.5772/intechopen.73124

ISBN: 978-1-78923-521-0

Print ISBN: 978-1-78923-520-3

eBook (PDF) ISBN: 978-1-83881-721-3

Copyright year: 2018

Books open for chapter submissions

6427 Total Chapter Downloads

9 Crossref Citations

4 Web of Science Citations

12 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: The General Problems of Human Clinical Nutritional and Pharmacological Observations of Capsaicin in Human Beings and Patients

By Gyula Mozsik


Open access peer-reviewed

2. Capsaicinoids and Vitamins in Hot Pepper and Their Role in Disease Therapy

By George F. Antonious


Open access peer-reviewed

3. Emerging Technologies to Improve Capsaicin Delivery and its Therapeutic Efficacy

By Veera Chandra Sekhar Reddy Chittepu, Poonam Kalhotra, Guillermo Ismael Osorio Revilla and Tzayhri Gallardo Velázquez


Open access peer-reviewed

4. A Matter of Taste: Capsaicinoid Diversity in Chile Peppers and the Importance to Human Food Preference

By Ivette Guzmán and Paul W. Bosland


Open access peer-reviewed

5. CAP and Metabolic Diseases: A Mini Review on Preclinical Mechanisms and Clinical Efficacy

By Baskaran Thyagarajan, Vivek Krishnan and Padmamalini Baskaran


Open access peer-reviewed

6. Predictors of Treatment Response to Capsaicin Patch

By Ancor Serrano Afonso


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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