Open access peer-reviewed Edited Volume

Capsaicin - Sensitive Neural Afferentation and the Gastrointestinal Tract

from Bench to Bedside

Edited by Gyula Mozsik

University of Pécs


The capsaicin, a component of paprika, has been used in the culinary practice of every day nutritional practice. This agent is known to cause a variety of actions in the body through activating capsaicin-sensitive afferent neurons. A recently launched book entitled, Capsaicin-Sensitive Neural Afferentation and the Gastrointestinal Tract: from Bench to Bedside, is attractive for several reasons. First, Prof. Mozsik, a chief editor of this book, is known internationally as an expert in capsaicin pharmacology. Since he has worked for many years as a head of internal medicine, taking care of patients with various GI diseases, he is able to make a correct interpretation of various findings obtained in basic researches to clinical events. Second, although there are many articles about capsaicin, they mostly deal with basic research and finding but do not include much about clinical finding. Third, this book encompassed review articles written by internationally accepted scientists leading the field of capsaicin research, who highlighted the current state of knowledge on pharmacology, physiology and clinical phathophysiology of capsaicin-sensitive afferent neurons, and discussed directions for future research. Overall, this book is for people who are interested in the capsaicin action in body.

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Capsaicin - Sensitive Neural Afferentation and the Gastrointestinal Tractfrom Bench to BedsideEdited by Gyula Mozsik

Published: July 16th 2014

DOI: 10.5772/57289

ISBN: 978-953-51-1631-8

eBook (PDF) ISBN: 978-953-51-7219-2

Copyright year: 2014

Books open for chapter submissions

18640 Total Chapter Downloads

2 Crossref Citations

6 Web of Science Citations

10 Dimensions Citations


Open access peer-reviewed

1. Discovery and Mechanism of Gastroprotective Action of Capsaicin

By János Szolcsányi


Open access peer-reviewed

2. Pharmacobotanical analysis and regulatory qualification of Capsicum fruits and Capsicum extracts. A survey.

By Monika Kuzma, Tibor Past, Gyula Mozsik and Pal Perjesi


Open access peer-reviewed

3. Allyl Isothiocyanate, a Pungent Ingredient of Wasabi and Mustard Oil, Impairs Gastric Paracellular Barrier in Primary Cultures from the Rat Stomach via TRPA1-Independent Pathway

By Kimihito Tashima, Misako Kabashima, Kenjiro Matsumoto, Shingo Yano, Susan J. Hagen and Syunji Horie


Open access peer-reviewed

4. Cooperative Effects of Neuronal Nitric Oxide Synthase and Endothelial Nitric Oxide Synthase on Gastric Hyperemic Response to Intragastric Capsaicin

By Syunji Horie, Masaki Raimura, Kenjiro Matsumoto, Takao Namiki, Katsutoshi Terasawa, John V. Priestley and Kimihito Tashima


Open access peer-reviewed

5. Modulation of Capsaicin-Induced Gastric Protection by Endogenous Prostaglandins through EP2/IP Receptors

By Koji Takeuchi


Open access peer-reviewed

6. Mechanism of Capsaicin-Stimulated Gastric HCO3- Secretion – Comparison with Mucosal Acidification

By Koji Takeuchi and Eitaro Aihara


Open access peer-reviewed

7. The Role of Capsaicin-Sensitive Afferent Nerves in Gastric Mucosal Protection Initiated Centrally or Peripherally under Experimental Conditions

By Klara Gyires


Open access peer-reviewed

8. Stable Gastric PentadecapeptideBPC 157, Somatosensory Neurons and Their Protection and Therapeutic Extensions — A Survey

By Predrag Sikiric


Open access peer-reviewed

9. Lafutidine Protects the NSAID-Induced Small Intestinal Lesions Mediated by Capsaicin-Sensitive Afferent Neurons

By Kikuko Amagase and Koji Takeuchi


Open access peer-reviewed

10. Capsaicin-Sensitive Afferent Nerves and the Human Gastrointestinal Tract

By Gyula Mózsik, András Dömötör, József Czimmer, Imre L. Szabó and János Szolcsányi


Open access peer-reviewed

11. Capsaicin is a New Gastrointestinal Mucosal Protecting Drug Candidate in Humans — Pharmaceutical Development and Production Based on Clinical Pharmacology

By Gyula Mózsik, Tibor Past, Tamás Habon, Zsuzsanna Keszthelyi, Pál Perjési, Mónika Kuzma, Barbara Sándor, János Szolcsányi, M.E. Abdel-Salam Omar and Mária Szalai


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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