\r\n\tUsually, the most popular alternative to RWG is the printed circuit technology: microstrip or coplanar lines, for instance. Despite the benefits of reduced cost, volume, and manufacturing easiness, these technologies present quite high power losses.
\r\n\r\n\t
\r\n\tNew planar and substrate integrated waveguides are being developed since 2001 to achieve the desired performance of an RWG but synthesized on one or more printed circuit boards. The first one of its kind was the substrate-integrated waveguide (SIW), which emulates a dielectric-filled RWG in a single circuit board where side walls are made of metallic via holes. Although SIW is a good alternative to classic planar technologies, the presence of lossy dielectric makes it impossible to get a performance similar to an RWG. In 2014 the empty substrate-integrated waveguide (ESIW) was introduced as a composite of three soldered metalized circuit board layers where the middle layer had been emptied to emulate an RWG. By now, ESIW is the best approach to an RWG in terms of performance but retains the characteristics of planar circuits: easiness, compactness, mass production, low volume, low weight, and low cost. Newer hybrid planar – 3D waveguiding structures have also arisen since then, both implementing waveguides of just one conductor (no TEM mode) or two conductors (pure TEM mode).
\r\n\t
\r\n\tThese novel hybrid technologies are receiving much research efforts and continuous advances are being published. The maturity of these technologies and their use by the communication industry may come with an increase in the performance of the communication devices and a major economic impact on the high-frequency communication sectors.
\r\n\tThe goals of this book are to present the basis of these new hybrid structures and to show the advances in the design of devices and systems, manufacturing processes and tests, as well as applications where these technologies can be used.
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Between 1895 and 1929, the film industry extended the initial appeal of very early films by evolving what many film scholars and teachers call “film language” and Noël Burch calls the Institutional Mode of Representation: a highly complex system using the many new technologies that emerged in the 1885–1929 period, such as moveable cameras, editing equipment, colour systems and sound recording [1]. Despite the complexity of this language, it was developed precisely to enhance the new medium’s appeal to mass audiences by intensifying the illusion of reality that it presented, while continuing to ensure that reading this “language” was a skill that could be learned at a very early age – so early, in fact, that most of us do not remember learning it. Hence the general assumption – or folk wisdom – that nobody has to learn how to understand moving-image media.
In this chapter, for brevity’s sake, I will refer to moving-image media as “movies” – by which I mean all the moving-image forms which use similar codes and conventions, including, for example, computer games, YouTube videos and advertisements, as well as cinema films and TV broadcasts. I begin by describing the folk wisdom’s contribution to an ideology that underpins theories and even policies concerning child management as well as informing the status of movies within hierarchies of cultural value. This frames the central argument of the chapter: that by recognising the distinctiveness and complexity of movie language, we can study and interpret children’s movie-viewing behaviour as a learning process, rather than as evidence of passivity or mesmerisation.
Scholars who wish to engage with this argument face considerable ethical and methodological challenges, when it becomes obvious that for most children in industrialised countries this learning must start in their second year of life and be sufficiently complete by the age of around 3 when they start being able to follow and enjoy some mainstream feature-length movies with other family members, and to play increasingly complex games on smartphones or tablets. This chapter discusses the challenges that have led to this age-group (which I will refer to as “toddlers”) being significantly under-researched, and it proposes potential solutions to the challenges of trying to understand their early learning about movies. For illustration, I draw on my research experience of studying toddlers within my own family, and on using embodied cognition perspectives in the analysis of video data.
In the UK in 1917, an independent inquiry on children and the cinema, commissioned by the National Council for Public Morals with the backing of cinema exhibitors, concluded that “the cinema, under wise guidance, may be made a powerful influence for good; if neglected, if its abuse is unchecked, its potentialities for evil are manifold.” ([2], p. xxi). This judgement encapsulates what could be called the “risks or benefits paradigm” which dominated research and policy in relation to children and movies until the second decade of the 21st century. In all cases, the potential benefits are dependent on substantial safeguards, e.g. “wise guidance”, and are not exemplified further than the
The need for “wise guidance” and the danger of “manifold potentialities for evil” remained the dominant, if less luridly described concerns in research on children’s relationships with movies for the rest of the 20th century. Advice to parents based on this research nevertheless had to recognise that most parents were unlikely to take much notice of detailed guidance for managing their children’s movie-watching, given their need for time to cook meals or take showers without having their toddlers underfoot. A compromise was found in the widely-accepted “two-hour rule” – the maximum daily amount of television-viewing that any child of two or older should be allowed (under-twos should not watch at all) – which the American Academy of Paediatrics recommended in 1999 [9] and which has been widely quoted. Today, many parents still nervously try to adhere to it without knowing where it comes from or what the ill-effects of movie-watching are supposed to be. And toddlers can be observed every day in shops, restaurants and public transport, sitting in their buggies or highchairs and happily poring over games, apps or YouTube on their parents’ smartphones or on iPads. In February 2021, Google’s 16.5 million results for a search on “lists of movies for toddlers” was headed by Good Housekeeping’s “The 15+ Best Toddler Movies for When You Need a Short Break”, whose introductory text, after a brief nod to the AAP’s “two-hour rule”, sympathetically supports movies’ “child-minder” role, carefully emphasising what we are all supposed to believe: that parents will only want to leave their kids watching movies for a “little bit of time” [10] – although most of the recommended movies are at least 90 minutes long!
The folly of attempting to impose a simple time-based “rule” on a complex cultural activity is finally beginning to be acknowledged: for example, in their study of parental anxieties about “screen time”, Blum-Ross and Livingstone argue that “for parents caught between fears of media harms and hopes for a digital future, a more nuanced consideration of the nature and purpose of screen media in different contexts is now urgent.” ([11], p. 185). Although they do not go into detail about what “nuanced” and “different contexts” might mean, this is an important challenge to researchers and one that I address in this chapter.
In the preface to the second edition of his book
Anyone who has taught Film Studies to beginners, even in higher education, will be aware that most adults, let alone children, cannot define any of the six devices that Branigan names, but given that we know (if only on the basis of the Good Housekeeping list referred to above) that by the age of about 3 most children can follow and enjoy at least some full-length mainstream feature films, then it has to be recognised that they can probably “read” these devices before they can speak fluently. Monaco’s dismissive remarks suggest that it’s not worth investigating anything that must be so easy to learn that toddlers can do it – although this has not deterred scholars from a huge range of significant research into language acquisition, which happens at the same age. Of course, language acquisition produces evidence in the form of utterances. Evidence of the ability to understand movie language is much harder to pin down.
Paul Messaris argues that many filmic devices, including for example eyeline matches, jump cuts and point of view shots, actually mimic people’s everyday perceptions and instinctive behaviour [14], many of which are established in very early childhood. Jerome Bruner describes how, even at nine months old, a child “looks out along the trajectory of an adult’s ‘point’ and, finding nothing there, turns back to check not only the adult’s direction of point but the line of visual regard as well” [15, p. 75]: this reflects the mechanisms of the point of view shot (the shot that follows a character assuming a meaningful expression, e.g. delight, terror, etc., as s/he looks at something out of the frame, raising audience expectations that the following shot will show us what s/he is looking at). Similarly, a cut to close-up mimics our behaviour when we suddenly see something we have been looking for (a mislaid bunch of keys, for example) or when we focus in shock on something unexpected (a spider in the bathtub, for example): our attention is tightly focused on the object in question, not on the surroundings. These are just two examples of the ways in which the development of the Institutional Mode of Representation involved moviemakers in creating devices which can seem complex to explain but have what is effectively a metaphoric
There is a noticeable gap in the Early Years research literature between studies of infants (i.e. children up to about 18 months old) and pre-schoolers (i.e. children of 3 years and older). Research on this age-group’s media-related behaviour is even rarer. As Plowman and Stevenson point out, such studies inevitably involve “practical and logistical considerations including gaining access, involving children as active research participants and negotiating consents” ([16], p. 330), whereas research samples of infants can be reached through clinics and those of children of 3 and up can be reached through nurseries.
The UK’s media regulatory body, Ofcom, part of whose remit is to promote and research media literacy, has an excellent, continuing research programme that monitors adults’ and children’s media use and attitudes and the changing roles of media in people’s lives. But it focuses mainly on children aged 5–15, with a smaller programme that gathers data on 3- and 4-year-olds: typically, they have nothing on the crucial 18–24-month period of life. Where toddlers’ movie-related behaviour has been studied, scholars have tended to favour experimental methods, (e.g. [5, 17, 18, 19, 20]) and large-scale studies have depended on parental surveys (e.g. [21, 22, 23]). Experiments and surveys cannot address what Lemish and Rice, in their 6–8-month study of 16 children aged between 6.5 and 29.5 months, call the “the richness of the interactions surrounding the television experience” ([24], p. 261) or what many parents – at least in Anglophone cultures – describe as typical “terrible twos” behaviour: incessantly adventurous, exploratory and self-willed. A more informed Early Years approach recognises that what is most difficult about studying toddlers is also the essential feature of their behaviour: continuous, often playful, self-driven learning.
Because of these challenges, many scholars have pointed out that longitudinal, ethnographically- styled and if possible home-based research models are the only way we can gain a fuller understanding of toddlers’ learning behaviours, given that these typically take place in the home environment [25, 26, 27, 28, 29, 30, 31]. Family members are well-positioned to undertake this successfully. Scholars who have studied their own children’s development, such as Piaget, Britton, Halliday, Weir and Edmiston, have been deservedly influential in the fields of education, Early Years, language and literacy [32, 33, 34, 35, 36]. While access, consent and ethical issues in these contexts are different from those in conventional ethnographies, there is a strong case to be made for the value of parental studies when the focus is on toddlers: children who are mobile, learning to talk, but whose language, and much of their behaviour, are idiosyncratic and hard for anyone outside the family to interpret. But as academic gatekeepers tend to be wary of studies that are based on “small samples” and are dubious about the ethical validity of scholars studying members of their own families, it is understandable that such studies are uncommon. This chapter draws on my own doctoral research study of my twin grandchildren’s movie-viewing between the ages of 22 and 42 months, in which I used video (taken unobtrusively on a smartphone) to capture aspects of their behaviour [37].
Levels of language development are of course the central issue in trying to study toddlers, if we are trying to gather evidence about their responses and thoughts in relation to movies. But even when toddlers can speak fairly fluently, their ideas and thought processes can still be hard to follow, even if we know them well. What we can also do however is observe their whole-body responses: posture, gesture, facial expressions, eye direction and movement. Although these are mainly instinctive, and can be fleeting, the developing field of embodied cognition theory has much to offer here.
In the Cartesian tradition which dominates popular beliefs about the separation of mind and body, and distinguishes between rational thought and instinctive behaviour, it is seen as important to control our emotions and beware of acting instinctively. Referring to instincts as “primitive” sounds derogatory, but as the neuroscientist Jaak Panksepp explains, the neural structures that govern important instinctive behaviour such as avoiding predators and spotting something edible were present in very early life-forms and many are shared today by all mammals [38]. So metaphoric devices in movies such as the point-of-view shot and the cut to close-up mimic skills that were obviously vital for survival in dangerous environments millions of years ago, and the fact that we all retain them today shows that we still need them. Using an evolutionary perspective to study toddlers’ instinctive behaviour can therefore be illuminating: what may often be interpreted as idiosyncratic or inexplicable actions can turn out to be potentially meaningful after all.
Although we differ genetically from chimpanzees by only 1.06% or less of our DNA [39], human babies take much longer than chimpanzee babies to become mobile and dextrous and to be able to eat food other than their mothers’ milk. But our big brains and hence our capacity for storing and analysing information, as well as the complex cultures we are all born into mean that, despite being physically almost helpless, human infants must begin social learning from the moment they are born. They communicate emotionally in enjoyable, intersubjective exchanges with their carers: “From birth, a child’s learning depends upon sharing his or her impulsive acting and thinking with other familiar persons, who themselves are experimenters, discoverers, and communicators, eager to share what they think and do” [40]. This forms the foundation for their later learning, as they become mobile and begin to be fluent in verbal language at around 12–18 months old. And if they have access to books, pictures, games and movies, this is when their interest in the meaning-potential of these media starts to grow exponentially. Thus, the second and third years of life are a phenomenally important period in which a great deal of our emotional, social and cultural learning starts to be established. In these three areas, we have to be cautious about the extent to which we can ever hope to gather hard evidence about what has been learned. What we can do however is establish that a child is learning and is investing an extraordinary amount of energy in the process. This should have a significant effect on the judgements we make about the value of toddlers’ movie-watching.
Panksepp describes four emotions that he says are likely to have arisen from basic environmental challenges: fear, panic, rage and seeking, each of which triggers immediate, instinctive actions. They remain deeply embedded in the ancient circuits of our brains because they have continued to be of survival value over millions of years, as humans evolved from earlier mammalian species. The only one of these four emotions whose meaning may not be immediately obvious is “seeking”. Panksepp uses this term to describe feelings of engagement and excitement: feelings that generate curiosity, anticipation and investigation. So not only would seeking get early humans (and their evolutionary predecessors) doing things like foraging and finding shelter, but it has always also been essential to logical thought and reflection: it “helps cement the perception of causal connections in the world and thereby creates ideas” ([38], pp. 144–149). In other words, it has been perhaps the most important emotion for us because it has driven human ingenuity and development (for both good and ill). So if we bear this in mind when we see a two-year-old intently gazing at a screen, rather than simply dismissing her behaviour as “mesmerised” or “zombie-like”, it makes better sense to interpret it instead as seeking: as an intense process of trying to make sense of what she is watching.
But “seeking” on its own does not tell us enough about what the attentive child is really after. Here Lesley Lancaster’s remarkable study of a two-year-old engaged, with her father, in making drawings and marks, may be helpful. Lancaster observes “physical and bodily actions [as] visible indicators of the course of abstract reasoning used whilst engaging with the difficult business of finding out about how a system of symbolic representation works” ([41], p. 132). She describes all of the child’s efforts to understand what her father is doing and to make her own meaningful marks on the page, as “characterized by an expectation of significance about the semiotic objects encountered. Children are introduced to them, one way or another, as having a social or affective purpose: the cartoon makes you laugh; the soft toy comforts; writing can entertain and inform” (p. 136). I find the phrase “expectation of significance” highly illuminating in the context of trying to understand what two-year-olds are up to when they clearly seem to be “seeking”.
The situation Lancaster describes and the viewing contexts that many toddlers experience is a social one. With toddlers’ acute awareness of what others are doing and what their emotional states are, most of them are familiar with occasions when other family members are not only intently watching a film, video or TV programme on a shared screen, but are also exhibiting emotional responses such as laughter, suspense, shock, disgust or surprise, and exchanging comments about what they are watching (readers who only ever watch movies in respectful silence can find exaggerated versions of this behaviour in the British TV show
For a toddler, this is also hard physical work. If he wants to maintain an absolutely steady gaze at something that is not actually in his hands (a big flat-screen television for example) he may well have to brace himself against a nearby object such as a piece of furniture. Studies of human movement and balance point out that a toddler’s centre of gravity is higher than that of older children and adults [42] and that in any case, most people can never maintain total stillness for very long [43]. So toddlers have to find ways of supporting themselves if they want to maintain steady visual contact, especially with a large area of moving images. Thus, bracing is often just an essential response for keeping the body stable. From other observations, I noted that if there is not a handy support, the child may stiffen his body and perhaps hunch his shoulders in the effort to maintain a steady position and may even have to pause now and then for a couple of seconds’ relaxation before resuming the rigid pose. An adult with an attentive toddler on their lap will be able to feel the child’s bodily tension and perhaps his grip on their limb or clothing as he maintains his gaze. If the child is also apprehensive about what he is looking at, the grip is likely to be tighter. Of course, if a child is sitting down watching a movie on a tablet or smartphone, keeping still is not such a problem, although the images are less overwhelming and satisfying.
It is also interesting to observe what a toddler does with her hands, if they are not already in use as part of the “braced” posture. It is likely that wherever the hands were before her attention was focused, they will remain in that position – so continuing to grip a bottle, cup or toy for example, or perhaps simply remaining placed on a nearby piece of furniture. There are parallels here with the way in which a predator such as a cat will instinctively “freeze” when it spots a movement that could be potential prey: if the cat is walking when this happens, one paw may remain raised so that no movement takes place that might alert the prey. A toddler suddenly enthralled by something in a movie will “freeze” in the same way.
The other obvious physical features of focused attention are facial expressions. These can be extremely fleeting, and in the case of toddlers with their relatively plump faces, it can be difficult to spot some expressions such as a frown. The major facial characteristic of more relaxed but still focused attentiveness in toddlers is commonly an open mouth, often accompanied by the typical toddler runny nose. Watching attentively for several minutes with one’s mouth open leads to dry lips, so lip-licking will happen regularly, and perhaps also some hasty nose-wipes with a handy sleeve. If a child is watching something attentively while drinking from a bottle or feeder cup, she may have to hold it to one side in order to maintain a gaze on the screen. Highly focused attention – in watching something suspenseful, for example – may be accompanied by deeper breathing – indicated by chest movements. Spotting the tiny rim of tears around a child’s eyelids when she is moved by something sad in a movie, is difficult in a live situation but can be spotted in video analysis.
It is when one realises how much energy has to be committed to maintaining this level of attention for any length of time, that it becomes apparent how completely inappropriate terms such as “passive” and mesmerised” are as characterisations of children’s focused attention on a movie. For an adult, standing rigidly still, holding tightly to a piece of furniture, frowning, breathing deeply and gazing open-mouthed and fixedly at something for a few minutes will convey some idea of how much physical energy a toddler can invest in maintaining focused attention. For a toddler, any learning is a very serious business, and the world is full of new things to discover and understand. Additionally, my earlier parallel with a cat’s hunting pose indicates that this kind of attentiveness has deep evolutionary roots. The early humans who survived their dangerous environments no doubt did so because they were as good as their non-human ancestors at concentrating very hard, quickly identifying and assessing potential threats or opportunities, and reacting appropriately. They must also have been good at working out solutions to practical problems or intellectual challenges and enjoying the satisfaction of having done so. While it is very often difficult to identify exactly what has caught a toddler’s attention in a movie, it has to be recognised that toddlers must have a strong motivation to invest so much energy.
Young children can easily be frightened by unexpected things that they do not understand, and this can include things that to a more experienced viewer are completely innocuous. A Google search for “my toddler is scared of TV” on 5th August 2021 yielded “about 8,240,000 results”, including numerous instructions to parents about the dangers of watching TV. Discussions on parents’ social media sometimes address similar issues, but are more likely to include reassuring advice such as “don’t worry, it’ll pass”. My own interest in studying toddlers’ movie-watching behaviour was sparked off by an event in which my 13-month-old twin grandchildren were suddenly terrified by what is clearly meant to be a light-hearted part of an episode of the BBC TV series
The common-sense parental view, that this is just a phase and will not result in long-term trauma, is probably well-founded, but it makes better sense still if we see it as part of a learning process. Most of us can be frightened, if only momentarily, by sudden and apparently inexplicable phenomena, but we can quickly be reassured if we can draw on our life-experiences to figure out what has happened or talk about it with others. Toddlers have less experience and more limited language skills than pre-schoolers, so their fear responses are magnified by the impossibility of sharing them. It usually does not help much if adults show alarm as well, and it can magnify the distress if co-viewers stop the movie as soon as a toddler expresses fear: watching it through to the end can often help a toddler understand what the point of the frightening bit actually was.
Another perspective on toddlers’ “inexplicable fears” is provided by Paul Kagan, who describes how 18–24-month-olds can often be distressed by what they see as violations of states of affairs “which adults have indicated are proper”. His examples include broken toys, damaged or dirty clothing and things missing from their usual places ([44], Chapter 5). He links this to their interest in categorising objects into groups sharing physical or functional similarities (p 88). So a toddler seeing something strange in a movie may be frightened rather than amused, because he sees it as “something that’s not supposed to happen”. An example of this from my research was when Connie (one of the twins, then aged 24 months) watched the
Toddlers’ responses to sad events or sad characters in movies are different from their fears, because they are already well-attuned to interpreting emotional states in others [45]. They may therefore find it too difficult to watch something sad but find it difficult to explain why. When the twins saw the main character crying in
In their 2018 survey of media use [46], Ofcom found that 96% of 3–4-year-olds watched TV on a TV set for an average of 14 hours per week, while 30% also watched TV on other devices, mainly on a tablet. 32% watched TV programmes via what are called “over the top” services, such as Netflix, Now TV or Amazon Prime Video. 36% of 3–4-year-olds played games for an average of over 6 hours per week, and 52% went online, for nearly 9 hours a week – much of which would have entailed going to YouTube for animated movies, funny videos or pranks. While most of these figures increased substantially for older age-groups, it was still the case that watching movies on a TV set, although declining slowly but steadily overall, was still a very important activity for three-year-olds. However, as any parent – and indeed any three-year-old – knows, three-year-olds are not the same as two-year-olds! It is extraordinary how little research there is on two-year-olds’ movie consumption, given that researchers, at least, have known since 2005 that many babies start watching movies at around 3 months [47].
In the absence of data on the viewing practices of children younger than 3, we have to make inferences about them. It is likely that at home, when parents are too busy to supervise very young children but know that movie-watching will probably occupy them for a while, they will be more likely to leave them to watch a movie on TV than to hand over a phone or tablet, which might get dropped or fought over; and in any case, the younger the children are, the less likely they will be able to deal with menus on VoD services, digital recorders or DVDs, and may thus be more likely to watch broadcast TV, switched on by a parent, carer or older sibling. So it may be reasonable to surmise that the percentage of two-year-olds watching movies on a TV set could even higher than that of 3–4-year-olds. But we also know that many toddlers do watch movies on mobile devices in their buggies when they are in shops, restaurants or other public places, so they may be watching more movies than older children, when we add up the number of opportunities they get to watch movies on any device. It may also mean that they may now have more opportunities to watch on their own, bearing out Ofcom’s claim that “consuming content is becoming a more solitary activity, with many children watching on their mobiles” ([46] p. 4).
But what are they watching? A toddler might be ranging over many types of movie, or she might be going through phases of favourite genres, such as funny cat videos on YouTube. In either case, the more significant outcomes for a two-year-old using a portable device to watch movies on her own would be firstly, that she would be developing her own preferences as regards genres, styles and content, rather than having to go along with others’ choices; secondly, that her facility with the technology would rapidly improve; and thirdly, that she would be occupied in self-directed learning as she re-viewed those movies that she judged worth watching more than once – perhaps even many times.
Toddlers’ interest in re-viewing movies is another phenomenon that worries many parents. A Google search on “my toddler is obsessed with watching …” in August 2021 yielded “about 8,630,000 results” with many social media comments revealing how this magnifies parents’ existing anxieties about “screen time” and is usually described in pathologizing terms such as “addiction”, while links to parental advice sites offers alarming “evidence” about the negative effects this is likely to have on their later lives. It is interesting that social media concerns about demands for repeat viewing are not paralleled in concerns about repeat reading. For example https://theconversation.com/theres-a-reason-your-child-wants-to-read-the-same-book-over-and-over-again-105733 advises parents who “might wonder if all this repetition is beneficial. The answer is yes. Your child is showing they enjoy this story, but also that they are still learning from the pictures, words, and the interactions you have as you read this book together”. If this is true for print media, then why would it not also be true for moving-image media?
In the contrast between the discussions of toddlers’ “obsessions” with movies and their demands for re-readings of books, we see the folk wisdom at work again. The idea that toddlers might need to re-view the same movie many times because they need to understand the medium, just as they need to hear stories and look at the pictures over and over again, does not figure in either social media debates or scholarly research, although there have been numerous important studies and reviews of toddlers’ cultural learning (e.g. [48, 49, 50, 51, 52]). We can excuse Vygotsky’s failure to mention children’s repeat-viewing of movies, given that he was writing in the 1930s and repeat-viewing was not available to the general public until the VHS format for video-cassette players became widely available in the late 1970s. But the same omission by scholars writing in the 1990s and later only serves to demonstrate the durability of the general belief that no one has to learn how to understand movies. It also demonstrates film scholars’ lack of interest in child audiences. Even David Bordwell, one of the major scholars in the field, has no qualms about defining the audiences he is referring to as “schooled perceivers in contemporary Western culture” ([53], p. 34) and no apparent interest in discussing how “perceivers” managed to get “schooled”.
There has been very little scholarly consideration of the concept that understanding a movie requires some effort, apart from Branigan’s 1992 footnote (quoted above). Bryant and Anderson’s edited collection of studies, drawn largely from developmental psychologists’ work in the 1970s and 1980s, did address “the act of television viewing itself” ([54], p xiii) before the expansion of the domestic VCR market (in the UK) and cable (in the US) radically changed the nature of most children’s access to this medium, by enabling re-viewing at will. An important feature of this book is a determination to oppose the then dominant idea among developmental psychologists that visual attention in young viewers “is primarily reactive and controlled by the television set,” and to make the radical counter-argument that “visual attention is actively under the control of the viewer, and is in the service of the viewer’s efforts to understand the television program” ([55], p. 1). One implication of this argument is that television has distinctive features that need to be understood, so several of the chapters address questions about the specificities of televisual codes and conventions. For example, Meringoff et al. are interested in “the distinctive cognitive consequences for children of their experience with television and other story-bearing media” (p. 151) and recognise the relevance of classical film theory to their research questions, although without any speculation about the age at which dissolves and jump cuts are understood:
Descriptions of the specific ways that editing techniques are used to suggest associations between shots and to imply transitions in time and space have aroused our curiosity about children’s ability to ‘read’ across film and television story lines. For instance, dissolves and jump cuts imply the passage of time only to those audience members who understand the meaning of those conventions. ([56], p. 157)
But, like most of the book’s contributors, their investigation involved older children (in their case 6–7-year-olds and 10–11-year-olds). Huston and Wright ask (again, of older cohorts of children), “What’s attractive about television? How does the child learn the codes of television and become increasingly sophisticated in understanding its content?” [57]. But they admit that “…one interpretation of our failure to find large developmental differences might be that we have not sampled children early enough to locate the critical period for familiarisation with television” (p. 43).
The contributors to Bryant and Anderson [54] recognised the need to study younger children but clearly did not want to tackle the methodological challenges of trying to elicit evidence about awareness of movie codes and conventions from children who would be too young to articulate them. They were less conscious of the further limitations imposed on their inquiries by their very schematic accounts of what the “codes of television” are, as well as by their commitment to experimental methods, their cognitivist approach and their reliance on “age and stage” models of child development.
When I was in the Education Department at the British Film Institute (1979–2007), where we worked with children, teachers, and policymakers to try and establish learning about movies within the UK’s mainstream primary school curricula, teachers constantly told us about their amazement at children’s responses to the materials and approaches we were offering. They were often sceptical about the movies we provided for them to show (non-mainstream short movies, not necessarily made for children but appropriate for them) and the approaches we suggested, such as getting children to listen to a soundtrack and discuss what they expected to see on the screen, and asking them to think about what features of a movie had generated their response (e.g. laughter, suspense, sadness). But in follow-up discussions they reported their pupils’ unexpected levels of knowledge and understanding when discussing movies, and the transformative effect on children of being allowed to talk about a medium they loved. One teacher wrote about her experience as follows:
I used one of the short films with my literacy set. I found the children motivated, engaged and exceedingly attentive right from the beginning. Their descriptive, inference and predictive skills were extended and they found that they were better at this than they thought because this form of media was familiar to them. The biggest difference was in the participation and quality of work from the boys who were usually not easily enthused by literacy. By the end of two weeks the children had extended their vocabulary and were able to write for a variety of purposes and in different styles with greater confidence. ([58], p. 27)
Even teachers in nursery schools (3- and 4-year-olds) had similar responses, for example:
When I was told that we were going to have to introduce visual literacy and do filming with nursery children, my heart sank and I thought, “oh no, another initiative’. I was dreading it. I thought I really have got to the end of my career and I can’t do this anymore. But when I tried the Baboon film [https://vimeo.com/58445945] with my children for the first time and used the method of play, pause, talk to the children, get them to predict, play all the way through I couldn’t believe haw enthralled the children were and how interested. There was no dialogue but they were glued … and it just took off from there. [quoted in [59], p. 82].
The characteristic teacher response to experiences such as this is excitement about the potential they seem to offer for getting children to be more enthusiastic about the prescribed curriculum. But the first teacher quoted above also comes close to what I see as a more important insight when she says “they found that they were better at this than they thought because this form of media was familiar to them”. What she and others who expressed similar excitement could not quite bring themselves to say was that the children they had been teaching were a lot more knowledgeable and confident than they had assumed – a confession most teachers understandably do not like to make. Few researchers have investigated the relationship between traditional literacy and movie knowledge, but the results can be illuminating. Comparing the work of two groups of primary school children, one of whom studied a novel in the traditional way, and the other who also made their own animated version of the novel, David Parker found that in the written work of the moving image class – in contrast to the work of the other class –
…we find a device used constantly in moving image media to predicate [sic] an audience towards a particular character and thereby create empathy. It is the use of point-of-view - seeing something through the eyes of another. What is interesting about these examples is not merely that a cinematic stance seems to be taken in terms of the written output, though that is certainly interesting in itself, but that in a piece of writing which aimed to establish the feelings or state of mind of a character, the class which was in the process of producing an animation understood that by spatially re-positioning the reader inside the character you could access feelings without necessarily describing them [60].
This observation indicates the potential value of exploring two cultural forms side by side, as a way of deepening understanding of both. It is an immensely important part of children’s learning to develop an understanding of how narratives work and of how to make judgements about whether a visual or verbal representation is “real” or “true”. Early movie-watching provides a thorough apprenticeship in both.
In Section 4 I discussed the challenges of trying to study toddlers’ viewing behaviour and trying to identify evidence of learning to understand the medium, suggesting that the only really effective way of doing this is through “longitudinal, ethnographically- styled and if possible home-based research models”. The findings from such studies could potentially challenge the dominant paradigms that prioritise digital media as the object of study and the potential risks of “exposure”, but a larger evidence base is needed. Although visiting researchers can and do attempt to do this – the EU Kids Online study is a good example of how this can form the basis of large-scale studies (https://www2.lse.ac.uk/media-and-communications/research/research-projects/eu-kids-online) – identifying significant aspects of toddlers’ viewing behaviour at the level of minute detail that I have described in this chapter is both essential if we are to understand pre-verbal learning and impossible unless done by researchers based in the home, who know the children well and are able to respond to toddlers’ spontaneous decisions to pay attention. The essential tool for such research is the use of video, given the need to capture minute changes in toddlers’ expressions, postures and gestures.
There is plenty of scholarly discussion about the ethics as well as the practicalities and value of using video as a research tool for studying very young children (e.g. [61, 62, 63, 64, 65]), almost all of which deals with video use by visiting scholars. These issues could potentially change in studies designed to involve family members in data-gathering: the “video diary” approach. If my arguments in this chapter are seen as persuasive, then one obvious next step could be to design a larger-scale study that co-opted a cohort of parents prepared to commit to a video diary project, gathering evidence of their toddlers’ movie-learning.
In this chapter I have set out the case for a paradigm shift in the study of children and media, on the basis that research in this field so far has largely avoided the study of children younger than 3, has failed to address the cultural dimensions and specificities of children’s media experiences, and has over-prioritised the risks of media consumption. I have backed up this case with examples of how close observation of toddlers’ behaviour as they watch moving-image media (referred to here as “movies”) indicates that they are involved in highly intense learning processes. My accounts of these exemplify the value of an embodied cognition approach in interpreting toddlers’ engagements with movies. With reference to nursery and primary school teachers’ discoveries of their pupils’ unexpectedly sophisticated approaches to movies, I argue that early movie-learning may be a significant contributor to children’s later learning. I have not minimised the considerable methodological and ethical challenges that would face any other scholars who wanted to undertake similar research, but I do argue for the value of longitudinal, ethnographically-styled studies, if possible by family members, as a way of exploring this perspective further.
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Over the past few decades, no major new types of antibiotics have been produced and almost all known antibiotics are increasingly losing their activity against pathogenic microorganisms. The levels of multi-drug resistant bacteria have also increased. It is known that worldwide, more than 60% of all antibiotics that are produced find their use in animal production for both therapeutic and non-therapeutic purposes. The use of antimicrobial agents in animal husbandry has been linked to the development and spread of resistant bacteria. Poultry products are among the highest consumed products worldwide but a lot of essential antibiotics are employed during poultry production in several countries; threatening the safety of such products (through antimicrobial residues) and the increased possibility of development and spread of microbial resistance in poultry settings. This chapter documents some of the studies on antibiotic usage in poultry farming; with specific focus on some selected bacterial species, their economic importance to poultry farming and reports of resistances of isolated species from poultry settings (farms and poultry products) to essential antibiotics.",book:{id:"6978",slug:"antimicrobial-resistance-a-global-threat",title:"Antimicrobial Resistance",fullTitle:"Antimicrobial Resistance - A Global Threat"},signatures:"Christian Agyare, Vivian Etsiapa Boamah, Crystal Ngofi Zumbi and\nFrank Boateng Osei",authors:[{id:"182058",title:"Dr.",name:"Christian",middleName:null,surname:"Agyare",slug:"christian-agyare",fullName:"Christian Agyare"},{id:"261271",title:"MSc.",name:"Crystal Ngofi",middleName:null,surname:"Zumbi",slug:"crystal-ngofi-zumbi",fullName:"Crystal Ngofi Zumbi"},{id:"261272",title:"MSc.",name:"Frank Boateng",middleName:null,surname:"Osei",slug:"frank-boateng-osei",fullName:"Frank Boateng Osei"},{id:"261273",title:"Dr.",name:"Vivian Etsiapa",middleName:null,surname:"Boamah",slug:"vivian-etsiapa-boamah",fullName:"Vivian Etsiapa Boamah"}]},{id:"39599",doi:"10.5772/50046",title:"Encapsulation Technology to Protect Probiotic Bacteria",slug:"encapsulation-technology-to-protect-probiotic-bacteria",totalDownloads:12297,totalCrossrefCites:40,totalDimensionsCites:81,abstract:null,book:{id:"3145",slug:"probiotics",title:"Probiotics",fullTitle:"Probiotics"},signatures:"María Chávarri, Izaskun Marañón and María Carmen Villarán",authors:[{id:"150285",title:"Dr.",name:"María",middleName:null,surname:"Chávarri Hueda",slug:"maria-chavarri-hueda",fullName:"María Chávarri Hueda"},{id:"151613",title:"MSc.",name:"Izaskun",middleName:null,surname:"Marañon",slug:"izaskun-maranon",fullName:"Izaskun Marañon"},{id:"151621",title:"Dr.",name:"Mª Carmen",middleName:null,surname:"Villarán",slug:"ma-carmen-villaran",fullName:"Mª Carmen Villarán"}]},{id:"39607",doi:"10.5772/50121",title:"Recent Application of Probiotics in Food and Agricultural Science",slug:"recent-application-of-probiotics-in-food-and-agricultural-science",totalDownloads:10098,totalCrossrefCites:28,totalDimensionsCites:74,abstract:null,book:{id:"3145",slug:"probiotics",title:"Probiotics",fullTitle:"Probiotics"},signatures:"Danfeng Song, Salam Ibrahim and Saeed Hayek",authors:[{id:"107905",title:"Prof.",name:"Salam",middleName:null,surname:"Ibrahim",slug:"salam-ibrahim",fullName:"Salam Ibrahim"},{id:"150202",title:"Dr.",name:"Danfeng",middleName:null,surname:"Song",slug:"danfeng-song",fullName:"Danfeng Song"},{id:"151025",title:"MSc.",name:"Saeed",middleName:null,surname:"Hayek",slug:"saeed-hayek",fullName:"Saeed Hayek"}]},{id:"49246",doi:"10.5772/61300",title:"Chitosan as a Biomaterial — Structure, Properties, and Electrospun Nanofibers",slug:"chitosan-as-a-biomaterial-structure-properties-and-electrospun-nanofibers",totalDownloads:4607,totalCrossrefCites:24,totalDimensionsCites:55,abstract:"Chitosan is a polysaccharide derived from chitin; chitin is the second most abundant polysaccharide in the world, after cellulose. Chitosan is biocompatible, biodegradable and non-toxic, so that it can be usedin medicalapplications such as antimicrobial and wound healing biomaterials. It also used as chelating agent due to its ability to bind with cholesterol, fats, proteins and metal ions.",book:{id:"4648",slug:"concepts-compounds-and-the-alternatives-of-antibacterials",title:"Concepts, Compounds and the Alternatives of Antibacterials",fullTitle:"Concepts, Compounds and the Alternatives of Antibacterials"},signatures:"H. M. Ibrahim and E.M.R. El- Zairy",authors:[{id:"90645",title:"Dr.",name:"Hassan",middleName:null,surname:"Ibrahim",slug:"hassan-ibrahim",fullName:"Hassan Ibrahim"},{id:"175694",title:"Dr.",name:"Enas",middleName:null,surname:"El- Zairy",slug:"enas-el-zairy",fullName:"Enas El- Zairy"}]},{id:"51065",doi:"10.5772/63499",title:"Role of the Biofilms in Wastewater Treatment",slug:"role-of-the-biofilms-in-wastewater-treatment",totalDownloads:6759,totalCrossrefCites:24,totalDimensionsCites:55,abstract:"Biological wastewater treatment systems play an important role in improving water quality and human health. This chapter thus briefly discusses different biological methods, specially biofilm technologies, the development of biofilms on different filter media, factors affecting their development as well as their structure and function. It also tackles various conventional and modern molecular techniques for detailed exploration of the composition, diversity and dynamics of biofilms. These data are crucial to improve the performance, robustness and stability of biofilm-based wastewater treatment technologies.",book:{id:"5197",slug:"microbial-biofilms-importance-and-applications",title:"Microbial Biofilms",fullTitle:"Microbial Biofilms - Importance and Applications"},signatures:"Shama Sehar and Iffat Naz",authors:[{id:"180364",title:"Dr.",name:"Iffat",middleName:null,surname:"Naz",slug:"iffat-naz",fullName:"Iffat Naz"},{id:"183345",title:"Dr.",name:"Shama",middleName:null,surname:"Sehar",slug:"shama-sehar",fullName:"Shama Sehar"}]}],mostDownloadedChaptersLast30Days:[{id:"65613",title:"The Methods for Detection of Biofilm and Screening Antibiofilm Activity of Agents",slug:"the-methods-for-detection-of-biofilm-and-screening-antibiofilm-activity-of-agents",totalDownloads:9033,totalCrossrefCites:11,totalDimensionsCites:20,abstract:"Biofilm producer microorganisms cause nosocomial and recurrent infections. Biofilm that is a sticky exopolysaccharide is the main virulence factor causing biofilm-related infections. Biofilm formation begins with attachment of bacteria to biotic surface such as host cell or abiotic surface such as prosthetic devices. After attachment, aggregation of bacteria is started by cell-cell adhesion. Aggregation continues with the maturation of biofilm. Dispersion is started by certain conditions such as phenol-soluble modulins (PSMs). By this way, sessile bacteria turn back into planktonic form. Bacteria embedded in biofilm (sessile form) are more resistant to antimicrobials than planktonic bacteria. So it is hard to treat biofilm-embedded bacteria than planktonic forms. For this reason, it is important to detect biofilm. There are a few biofilm detection and biofilm production methods on prosthetics, methods for screening antibacterial effect of agents against biofilm-embedded microorganism and antibiofilm effect of agents against biofilm production and mature biofilm. The aim of this chapter is to overview direct and indirect methods such as microscopy, fluorescent in situ hybridization, and Congo red agar, tube method, microtiter plate assay, checkerboard assay, plate counting, polymerase chain reaction, mass spectrometry, MALDI-TOF, and biological assays used by antibiofilm researches.",book:{id:"8427",slug:"antimicrobials-antibiotic-resistance-antibiofilm-strategies-and-activity-methods",title:"Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods",fullTitle:"Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods"},signatures:"Sahra Kırmusaoğlu",authors:[{id:"179460",title:"Associate Prof.",name:"Sahra",middleName:null,surname:"Kırmusaoğlu",slug:"sahra-kirmusaoglu",fullName:"Sahra Kırmusaoğlu"}]},{id:"62553",title:"Antibiotic Use in Poultry Production and Its Effects on Bacterial Resistance",slug:"antibiotic-use-in-poultry-production-and-its-effects-on-bacterial-resistance",totalDownloads:7129,totalCrossrefCites:42,totalDimensionsCites:82,abstract:"A surge in the development and spread of antibiotic resistance has become a major cause for concern. Over the past few decades, no major new types of antibiotics have been produced and almost all known antibiotics are increasingly losing their activity against pathogenic microorganisms. The levels of multi-drug resistant bacteria have also increased. It is known that worldwide, more than 60% of all antibiotics that are produced find their use in animal production for both therapeutic and non-therapeutic purposes. The use of antimicrobial agents in animal husbandry has been linked to the development and spread of resistant bacteria. Poultry products are among the highest consumed products worldwide but a lot of essential antibiotics are employed during poultry production in several countries; threatening the safety of such products (through antimicrobial residues) and the increased possibility of development and spread of microbial resistance in poultry settings. This chapter documents some of the studies on antibiotic usage in poultry farming; with specific focus on some selected bacterial species, their economic importance to poultry farming and reports of resistances of isolated species from poultry settings (farms and poultry products) to essential antibiotics.",book:{id:"6978",slug:"antimicrobial-resistance-a-global-threat",title:"Antimicrobial Resistance",fullTitle:"Antimicrobial Resistance - A Global Threat"},signatures:"Christian Agyare, Vivian Etsiapa Boamah, Crystal Ngofi Zumbi and\nFrank Boateng Osei",authors:[{id:"182058",title:"Dr.",name:"Christian",middleName:null,surname:"Agyare",slug:"christian-agyare",fullName:"Christian Agyare"},{id:"261271",title:"MSc.",name:"Crystal Ngofi",middleName:null,surname:"Zumbi",slug:"crystal-ngofi-zumbi",fullName:"Crystal Ngofi Zumbi"},{id:"261272",title:"MSc.",name:"Frank Boateng",middleName:null,surname:"Osei",slug:"frank-boateng-osei",fullName:"Frank Boateng Osei"},{id:"261273",title:"Dr.",name:"Vivian Etsiapa",middleName:null,surname:"Boamah",slug:"vivian-etsiapa-boamah",fullName:"Vivian Etsiapa Boamah"}]},{id:"65914",title:"Introductory Chapter: The Action Mechanisms of Antibiotics and Antibiotic Resistance",slug:"introductory-chapter-the-action-mechanisms-of-antibiotics-and-antibiotic-resistance",totalDownloads:4310,totalCrossrefCites:6,totalDimensionsCites:8,abstract:null,book:{id:"8427",slug:"antimicrobials-antibiotic-resistance-antibiofilm-strategies-and-activity-methods",title:"Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods",fullTitle:"Antimicrobials, Antibiotic Resistance, Antibiofilm Strategies and Activity Methods"},signatures:"Sahra Kırmusaoğlu, Nesrin Gareayaghi and Bekir S. Kocazeybek",authors:[{id:"179460",title:"Associate Prof.",name:"Sahra",middleName:null,surname:"Kırmusaoğlu",slug:"sahra-kirmusaoglu",fullName:"Sahra Kırmusaoğlu"},{id:"248288",title:"Prof.",name:"Bekir",middleName:null,surname:"Kocazeybek",slug:"bekir-kocazeybek",fullName:"Bekir Kocazeybek"},{id:"406463",title:"Dr.",name:"Nesrin",middleName:null,surname:"Gareayaghi",slug:"nesrin-gareayaghi",fullName:"Nesrin Gareayaghi"}]},{id:"50992",title:"Probiotics: A Comprehensive Review of Their Classification, Mode of Action and Role in Human Nutrition",slug:"probiotics-a-comprehensive-review-of-their-classification-mode-of-action-and-role-in-human-nutrition",totalDownloads:5325,totalCrossrefCites:14,totalDimensionsCites:26,abstract:"Probiotics are live microorganisms that live in gastrointestinal (GI) tract and are beneficial for their hosts and prevent certain diseases. In this chapter, after a complete introduction to probiotics, definition, mechanism of action, and their classification, currently used organisms will be discussed in detail. Moreover, different kinds of nutritional synthetic products of probiotics along with their safety and drug interaction will be noticed. This chapter mentions all clinical trial studies that have been done to evaluate probiotic efficacy with a focus on gastrointestinal diseases.",book:{id:"5193",slug:"probiotics-and-prebiotics-in-human-nutrition-and-health",title:"Probiotics and Prebiotics in Human Nutrition and Health",fullTitle:"Probiotics and Prebiotics in Human Nutrition and Health"},signatures:"Amirreza Khalighi, Reza Behdani and Shabnam Kouhestani",authors:[{id:"179560",title:"Dr.",name:"Amirreza",middleName:null,surname:"Khalighi",slug:"amirreza-khalighi",fullName:"Amirreza Khalighi"},{id:"185238",title:"Dr.",name:"Reza",middleName:null,surname:"Behdani",slug:"reza-behdani",fullName:"Reza Behdani"},{id:"185239",title:"Dr.",name:"Shabnam",middleName:null,surname:"Kouhestani",slug:"shabnam-kouhestani",fullName:"Shabnam Kouhestani"}]},{id:"56849",title:"Physiology and Pathology of Innate Immune Response Against Pathogens",slug:"physiology-and-pathology-of-innate-immune-response-against-pathogens",totalDownloads:6083,totalCrossrefCites:20,totalDimensionsCites:26,abstract:"Pathogen infections are recognized by the immune system, which consists of two types of responses: an innate immune response and an antigen-specific adaptive immune response. The innate response is characterized by being the first line of defense that occurs rapidly in which leukocytes such as neutrophils, monocytes, macrophages, eosinophils, mast cells, dendritic cells, etc., are involved. These cells recognize the pathogen-associated molecular patterns (PAMPs), which have been evolutionarily conserved by the diversity of microorganisms that infect humans. Recognition of these pathogen-associated molecular patterns occurs through pattern recognition receptors such as Toll-like receptors and some other intracellular receptors such as nucleotide oligomerization domain (NOD), with the aim of amplifying the inflammation and activating the adaptive cellular immune response, through the antigenic presentation. In the present chapter, we will review the importance of the main components involved in the innate immune response, such as different cell types, inflammatory response, soluble immune mediators and effector mechanisms exerted by the immune response against bacteria, viruses, fungi, and parasites; all with the purpose of eliminating them and eradicating the infection of the host.",book:{id:"5975",slug:"physiology-and-pathology-of-immunology",title:"Physiology and Pathology of Immunology",fullTitle:"Physiology and Pathology of Immunology"},signatures:"José Luis Muñoz Carrillo, Flor Pamela Castro García, Oscar\nGutiérrez Coronado, María Alejandra Moreno García and Juan\nFrancisco Contreras Cordero",authors:[{id:"214236",title:"Dr.",name:"Jose Luis",middleName:null,surname:"Muñoz-Carrillo",slug:"jose-luis-munoz-carrillo",fullName:"Jose Luis Muñoz-Carrillo"},{id:"216080",title:"Dr.",name:"Alejandra",middleName:null,surname:"Moreno-García",slug:"alejandra-moreno-garcia",fullName:"Alejandra Moreno-García"},{id:"216081",title:"Dr.",name:"Oscar",middleName:null,surname:"Gutiérrez-Coronado",slug:"oscar-gutierrez-coronado",fullName:"Oscar Gutiérrez-Coronado"},{id:"216082",title:"Dr.",name:"Pamela",middleName:null,surname:"Castro-García",slug:"pamela-castro-garcia",fullName:"Pamela Castro-García"},{id:"220717",title:"Dr.",name:"Juan Francisco",middleName:null,surname:"Contreras Cordero",slug:"juan-francisco-contreras-cordero",fullName:"Juan Francisco Contreras Cordero"}]}],onlineFirstChaptersFilter:{topicId:"13",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"81760",title:"On the Selective Isolation of Actinobacteria from Different Mexican Ecosystems",slug:"on-the-selective-isolation-of-actinobacteria-from-different-mexican-ecosystems",totalDownloads:3,totalDimensionsCites:0,doi:"10.5772/intechopen.104699",abstract:"Actinobacteria isolated from less studied sites on our planet represent a huge opportunity for the discovery of novel microorganisms that may produce unique compounds with biological activity. The class actinobacteria encompasses 80% of the microbes that produce the antibacterial compounds used in medicine today. However, the resistance acquired/showed by pathogenic microorganisms opens the opportunity to explore Mexican ecosystems as a source of novel actinobacteria. Air samples have shown to be an excellent site of study, marine ecosystems which include sediments and marine organisms are important sources of novel actinobacteria and soil samples are still a promising source to isolate this microbial group. The isolation of novel actinobacteria is a dynamic strategy that depends on the expertise, patience, and talent of the techniques applied and needs to be fully explored to untap the unknown actinobacterial diversity with potential in biology.",book:{id:"10893",title:"Actinobacteria",coverURL:"https://cdn.intechopen.com/books/images_new/10893.jpg"},signatures:"Erika T. Quintana, Luis A. Maldonado, Luis Contreras-Castro, Amanda Alejo-Viderique, Martha E. Esteva García, Claudia J. Hernández-Guerrero, Juan C. Cancino-Díaz, Carlos Sánchez, Luis A. Ladino, Juan Esteban Martínez-Gómez and Noemí Matías-Ferrer"},{id:"81741",title:"Chronic Intraocular Leptospiral Infection Relying on Biofilm Formation inside the Vitreous Cavity Leads to Recurrent Uveitis in Horses",slug:"chronic-intraocular-leptospiral-infection-relying-on-biofilm-formation-inside-the-vitreous-cavity-le",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.104527",abstract:"Equine recurrent uveitis (ERU) is a disease known and feared for centuries, as it almost always leads to blindness even with careful and meticulous conservative treatment of the individual episodes of uveitis. In about one-third of horses, both eyes are affected, often necessitating euthanasia. A link between ERU and leptospiral infection has been suspected for nearly 80 years. Vitreous lavage (vitrectomy) can preserve vision in affected eyes. After surgery, no further episodes of uveitis occur in up to more than 95% of operated eyes. With routine performance of vitrectomies, numerous vitreous samples could be used for further investigations. Intraocular anti-Leptospira antibody production was proven, leptospires could be cultured from the vitreous samples, and the LipL32 gene could be detected in the vitreous samples by PCR. Thus, there was convincing evidence of a chronic intraocular leptospiral infection, which can be eliminated most reliably by vitrectomy. Recently, it has been shown that the intraocular leptospires produce biofilm in the equine vitreous. Biofilm formation explains not only the success of vitrectomy, but also the survival of leptospires in the vitreous cavity for many years despite the presence of high intraocular antibody titers and immunocompetent cells, as well as the high tolerance to antibiotics.",book:{id:"11092",title:"Bacterial Biofilms",coverURL:"https://cdn.intechopen.com/books/images_new/11092.jpg"},signatures:"Bettina Wollanke and Hartmut Gerhards"},{id:"81758",title:"Growing Environmental Bacterium Biofilms in PEO Cryogels for Environmental Biotechnology Application",slug:"growing-environmental-bacterium-biofilms-in-peo-cryogels-for-environmental-biotechnology-application",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.104813",abstract:"This Chapter discusses the entrapment, growing and biofilm formation by an environmental bacterium immobilized in polyethyleneoxide cryogel to be applied in environmental biotechnology. The KCM-R5 bacterium was isolated from the heavy metal-polluted environment near a large Pb-Zn smelter, also producing precious metals in Bulgaria. Molecular-genetic analysis revealed affiliation with Pseudomonas rhodesiae. The strain is capable of growing in high concentrations of phenol and different phenol derivatives. Polyethylene oxide was found to be friendly and nontoxic to bacteria polymer enabling bacteria easy to penetrate in it and fast to grow. KCM-R5 biofilms were grown for 30 days in batch culture with phenol (300-1000 mg L−1) dissolved in the mineral medium. The bacterium was able to involve phenol in its metabolism and use it as a single carbon supplier. The results obtained in the study showed 98% phenol biodegradation using the biotech installation described. The proposed PEO cryogel-P. rhodesiae KCM-R5 bacterium biotech biofilter can be used for environmental biotechnology application in industrial wastewater detoxification.",book:{id:"11092",title:"Bacterial Biofilms",coverURL:"https://cdn.intechopen.com/books/images_new/11092.jpg"},signatures:"Galina Satchanska"},{id:"81733",title:"Impairment of the Cardiovascular System during SARS-CoV-2 Infection",slug:"impairment-of-the-cardiovascular-system-during-sars-cov-2-infection",totalDownloads:2,totalDimensionsCites:0,doi:"10.5772/intechopen.103964",abstract:"Although the infection with the severe acute respiratory syndrome (SARS-CoV-2) virus affects primarily the respiratory system, it became evident from the very beginning that the coronavirus disease 2019 (COVID-19) is frequently associated with a large spectrum of cardiovascular involvements such as myocarditis/pericarditis, acute coronary syndrome, arrhythmias, or thromboembolic events, explained by a multitude of pathophysiological mechanisms. Individuals already suffering of significant cardiovascular diseases were more likely to be infected with the virus, had a worse evolution during COVID-19, with further deterioration of their basal condition and increased morbidity and mortality, but significant cardiac dysfunctions were diagnosed even in individuals without a history of heart diseases or being at low risk to develop such a pathology. Cardiovascular complications may occur anytime during the course of COVID-19, persisting even during recovery and, potentially, explaining many of the persisting symptoms included now in terms as subacute or long-COVID-19. It is now well accepted that in COVID-19, the occurrence of cardiovascular impairment represents a significant negative prognostic factor, immensely rising the burden of cardiovascular pathologies.",book:{id:"11369",title:"RNA Viruses",coverURL:"https://cdn.intechopen.com/books/images_new/11369.jpg"},signatures:"Cristina Tudoran, Mariana Tudoran, Voichita Elena Lazureanu, Adelina Raluca Marinescu, Dorin Novacescu and Talida Georgiana Cut"},{id:"81718",title:"Advances in the Development of Anti-Trichinella spiralis Vaccine, Challenges, and Future Prospective",slug:"advances-in-the-development-of-anti-trichinella-spiralis-vaccine-challenges-and-future-prospective",totalDownloads:6,totalDimensionsCites:0,doi:"10.5772/intechopen.103027",abstract:"Trichinellosis is a food-borne, zoonotic disease that causes infection by a nematode parasite belonging to the genus Trichinella. This is an important disease, and its causative agent is prevalent throughout the world (cosmopolitan). More clinical awareness of trichinellosis is required due to its many outbreaks, increase in the consumption of pork meat and its by-products. Trichinellosis is an epizootic in nature and its economic burden is associated with the prevention of this disease from the human food chain. This disease is transmitted from animals to humans through the consumption of raw or undercooked meat containing encapsulated muscle larvae of Trichinella spiralis. This paper demonstrates the direct effect of progesterone (P4) and mifepristone (RU486) on the progesterone receptors of T. spiralis. Also, studied the challenges in the preparation of DNA and recombinant protein vaccination to control trichinellosis. It is simply done this study at different life cycle developmental stages of T. spiralis. Vaccines development against T. spiralis infection is the new paradime shift from prevention of trichinellosis to fulfilling the food safety requirements.",book:{id:"11380",title:"Parasitic Helminths and Zoonoses - From Basic to Applied Research",coverURL:"https://cdn.intechopen.com/books/images_new/11380.jpg"},signatures:"Muhammad Tahir Aleem, Ruofeng Yan, Asad Khan, Rida Asrar, Amna Shakoor, Areej Asif, Zhaohai Wen, Zhengqing Yu, Muhammad Abdullah Malik, Tauseef-ur-Rehman, Rao Zahid Abbas, Muhammad Mohsin, Xiaokai Song, Lixin Xu and Xiangrui Li"},{id:"81699",title:"Efflux Pumps among Urinary E. coli and K. pneumoniae Local Isolates in Hilla City, Iraq",slug:"efflux-pumps-among-urinary-e-coli-and-k-pneumoniae-local-isolates-in-hilla-city-iraq",totalDownloads:4,totalDimensionsCites:0,doi:"10.5772/intechopen.104408",abstract:"Urinary tract infections (UTI) are the most common bacterial infections affecting humans. Escherichia coli and Klebsiella pneumoniae were common enterobacteria engaged with community-acquired UTIs. Efflux pumps were vital resistance mechanisms for antibiotics, especially among enterobacteria. Overexpression of an efflux system, which results in a decrease in antibiotic accumulation, is an effective mechanism for drug resistance. The ATP-binding cassette (ABC) transporters, small multidrug resistance (SMR), and multidrug and toxic compound extrusion (MATE) families, the major facilitator superfamily (MFS), and the resistance-nodulation- cell division (RND) family are the five superfamilies of efflux systems linked to drug resistance. This chapter highlights the results of studying the prevalence of efflux pump genes among local isolates of E. coli and K. pneumoniae in Hilla City, Iraq. class RND AcrAB-TolC, AcrAD-TolC, and AcrFE-TolC genes detected by conventional PCR of E. coli and K. pneumoniae respectively. The result revealed approximately all studied efflux transporter were found in both E. coli and K. pneumoniae in different percentages. Biofilm formation were observed in 50(100%) of K. pneumoniae and 49(98%) of E. coli isolates were biofilm former and follow: 30(60%), 20(40%) were weak, 12(24%), 22(44%) were moderate and 7(14%) and 8(16%) were Strong biofilm former for E. coli and K. pneumoniae, respectively.",book:{id:"11373",title:"The Global Antimicrobial Resistance Epidemic – Innovative Approaches and Cutting-Edge Solutions",coverURL:"https://cdn.intechopen.com/books/images_new/11373.jpg"},signatures:"Hussein Al-Dahmoshi, Sahar A. 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The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}}]},series:{item:{id:"13",title:"Veterinary Medicine and Science",doi:"10.5772/intechopen.73681",issn:"2632-0517",scope:"Paralleling similar advances in the medical field, astounding advances occurred in Veterinary Medicine and Science in recent decades. These advances have helped foster better support for animal health, more humane animal production, and a better understanding of the physiology of endangered species to improve the assisted reproductive technologies or the pathogenesis of certain diseases, where animals can be used as models for human diseases (like cancer, degenerative diseases or fertility), and even as a guarantee of public health. Bridging Human, Animal, and Environmental health, the holistic and integrative “One Health” concept intimately associates the developments within those fields, projecting its advancements into practice. This book series aims to tackle various animal-related medicine and sciences fields, providing thematic volumes consisting of high-quality significant research directed to researchers and postgraduates. It aims to give us a glimpse into the new accomplishments in the Veterinary Medicine and Science field. 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After almost 32 years of teaching at the University of Trás-os-Montes and Alto Douro, she recently moved to the University of Évora, Department of Veterinary Medicine, where she teaches in the field of Animal Reproduction and Clinics. Her primary research areas include the molecular markers of the endometrial cycle and the embryo–maternal interaction, including oxidative stress and the reproductive physiology and disorders of sexual development, besides the molecular determinants of male and female fertility. She often supervises students preparing their master's or doctoral theses. 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A dynamic career research platform which is based on the thematic areas of comparative vertebrate physiology, stress endocrinology, reproductive endocrinology, animal health and welfare, and conservation biology. \nEdward has supervised 40 research students and published over 60 peer reviewed research.",institutionString:null,institution:{name:"University of Queensland",institutionURL:null,country:{name:"Australia"}}},editorTwo:null,editorThree:null},{id:"20",title:"Animal Nutrition",coverUrl:"https://cdn.intechopen.com/series_topics/covers/20.jpg",isOpenForSubmission:!0,editor:{id:"175967",title:"Dr.",name:"Manuel",middleName:null,surname:"Gonzalez Ronquillo",slug:"manuel-gonzalez-ronquillo",fullName:"Manuel Gonzalez Ronquillo",profilePictureURL:"https://mts.intechopen.com/storage/users/175967/images/system/175967.png",biography:"Dr. Manuel González Ronquillo obtained his doctorate degree from the University of Zaragoza, Spain, in 2001. He is a research professor at the Faculty of Veterinary Medicine and Animal Husbandry, Autonomous University of the State of Mexico. He is also a level-2 researcher. He received a Fulbright-Garcia Robles fellowship for a postdoctoral stay at the US Dairy Forage Research Center, Madison, Wisconsin, USA in 2008–2009. He received grants from Alianza del Pacifico for a stay at the University of Magallanes, Chile, in 2014, and from Consejo Nacional de Ciencia y Tecnología (CONACyT) to work in the Food and Agriculture Organization’s Animal Production and Health Division (AGA), Rome, Italy, in 2014–2015. He has collaborated with researchers from different countries and published ninety-eight journal articles. He teaches various degree courses in zootechnics, sheep production, and agricultural sciences and natural resources.\n\nDr. Ronquillo’s research focuses on the evaluation of sustainable animal diets (StAnD), using native resources of the region, decreasing carbon footprint, and applying meta-analysis and mathematical models for a better understanding of animal production.",institutionString:null,institution:{name:"Universidad Autónoma del Estado de México",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null},{id:"28",title:"Animal Reproductive Biology and Technology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/28.jpg",isOpenForSubmission:!0,editor:{id:"177225",title:"Prof.",name:"Rosa Maria Lino Neto",middleName:null,surname:"Pereira",slug:"rosa-maria-lino-neto-pereira",fullName:"Rosa Maria Lino Neto Pereira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bS9wkQAC/Profile_Picture_1624519982291",biography:"Rosa Maria Lino Neto Pereira (DVM, MsC, PhD and) is currently a researcher at the Genetic Resources and Biotechnology Unit of the National Institute of Agrarian and Veterinarian Research (INIAV, Portugal). She is the head of the Reproduction and Embryology Laboratories and was lecturer of Reproduction and Reproductive Biotechnologies at Veterinary Medicine Faculty. She has over 25 years of experience working in reproductive biology and biotechnology areas with a special emphasis on embryo and gamete cryopreservation, for research and animal genetic resources conservation, leading research projects with several peer-reviewed papers. Rosa Pereira is member of the ERFP-FAO Ex situ Working Group and of the Management Commission of the Portuguese Animal Germplasm Bank.",institutionString:"The National Institute for Agricultural and Veterinary Research. Portugal",institution:null},editorTwo:null,editorThree:null}]},overviewPageOFChapters:{paginationCount:25,paginationItems:[{id:"81793",title:"Canine parvovirus-2: An Emerging Threat to Young Pets",doi:"10.5772/intechopen.104846",signatures:"Mithilesh Singh, Rajendran Manikandan, Ujjwal Kumar De, Vishal Chander, Babul Rudra Paul, Saravanan Ramakrishnan and Darshini Maramreddy",slug:"canine-parvovirus-2-an-emerging-threat-to-young-pets",totalDownloads:0,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"81271",title:"The Diversity of Parvovirus Telomeres",doi:"10.5772/intechopen.102684",signatures:"Marianne Laugel, Emilie Lecomte, Eduard Ayuso, Oumeya Adjali, Mathieu Mével and Magalie Penaud-Budloo",slug:"the-diversity-of-parvovirus-telomeres",totalDownloads:22,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Recent Advances in Canine Medicine",coverURL:"https://cdn.intechopen.com/books/images_new/11580.jpg",subseries:{id:"19",title:"Animal Science"}}},{id:"80187",title:"Potential Utilization of Insect Meal as Livestock Feed",doi:"10.5772/intechopen.101766",signatures:"Sipho Moyo and Busani Moyo",slug:"potential-utilization-of-insect-meal-as-livestock-feed",totalDownloads:100,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Animal Feed Science and Nutrition - Production, Health and Environment",coverURL:"https://cdn.intechopen.com/books/images_new/10830.jpg",subseries:{id:"20",title:"Animal Nutrition"}}},{id:"79909",title:"Cryopreservation Methods and Frontiers in the Art of Freezing Life in Animal Models",doi:"10.5772/intechopen.101750",signatures:"Feda S. 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She obtained her Ph.D. in Veterinary Sciences from the University of Trás-os-Montes e Alto Douro, Portugal. After almost 32 years of teaching at the University of Trás-os-Montes and Alto Douro, she recently moved to the University of Évora, Department of Veterinary Medicine, where she teaches in the field of Animal Reproduction and Clinics. Her primary research areas include the molecular markers of the endometrial cycle and the embryo–maternal interaction, including oxidative stress and the reproductive physiology and disorders of sexual development, besides the molecular determinants of male and female fertility. She often supervises students preparing their master's or doctoral theses. She is also a frequent referee for various journals.",institutionString:null,institution:{name:"University of Évora",institutionURL:null,country:{name:"Portugal"}}}]},{type:"book",id:"7144",title:"Veterinary Anatomy and Physiology",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7144.jpg",slug:"veterinary-anatomy-and-physiology",publishedDate:"March 13th 2019",editedByType:"Edited by",bookSignature:"Catrin Sian Rutland and Valentina Kubale",hash:"75cdacb570e0e6d15a5f6e69640d87c9",volumeInSeries:2,fullTitle:"Veterinary Anatomy and Physiology",editors:[{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. 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He worked as a post-doctoral fellow at the Public Health Research Institute (PHRI), Newark, NJ for four years before accepting a three-year faculty position at Brigham Young University-Hawaii. Dr. Engohang-Ndong is a tenured faculty member with the academic rank of Full Professor at Kent State University, Ohio, where he teaches a wide range of biological science courses and pursues his research in medical and environmental microbiology. Recently, he expanded his research interest to epidemiology and biostatistics of chronic diseases in Gabon.",institutionString:"Kent State University",institution:{name:"Kent State University",country:{name:"United States of America"}}},{id:"188773",title:"Prof.",name:"Emmanuel",middleName:null,surname:"Drouet",slug:"emmanuel-drouet",fullName:"Emmanuel Drouet",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/188773/images/system/188773.png",biography:"Emmanuel Drouet, PharmD, is a Professor of Virology at the Faculty of Pharmacy, the University Grenoble-Alpes, France. As a head scientist at the Institute of Structural Biology in Grenoble, Dr. Drouet’s research investigates persisting viruses in humans (RNA and DNA viruses) and the balance with our host immune system. He focuses on these viruses’ effects on humans (both their impact on pathology and their symbiotic relationships in humans). He has an excellent track record in the herpesvirus field, and his group is engaged in clinical research in the field of Epstein-Barr virus diseases. He is the editor of the online Encyclopedia of Environment and he coordinates the Universal Health Coverage education program for the BioHealth Computing Schools of the European Institute of Science.",institutionString:null,institution:{name:"Grenoble Alpes University",country:{name:"France"}}},{id:"131400",title:"Prof.",name:"Alfonso J.",middleName:null,surname:"Rodriguez-Morales",slug:"alfonso-j.-rodriguez-morales",fullName:"Alfonso J. Rodriguez-Morales",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/131400/images/system/131400.png",biography:"Dr. Rodriguez-Morales is an expert in tropical and emerging diseases, particularly zoonotic and vector-borne diseases (especially arboviral diseases). He is the president of the Travel Medicine Committee of the Pan-American Infectious Diseases Association (API), as well as the president of the Colombian Association of Infectious Diseases (ACIN). He is a member of the Committee on Tropical Medicine, Zoonoses, and Travel Medicine of ACIN. He is a vice-president of the Latin American Society for Travel Medicine (SLAMVI) and a Member of the Council of the International Society for Infectious Diseases (ISID). Since 2014, he has been recognized as a Senior Researcher, at the Ministry of Science of Colombia. He is a professor at the Faculty of Medicine of the Fundacion Universitaria Autonoma de las Americas, in Pereira, Risaralda, Colombia. He is an External Professor, Master in Research on Tropical Medicine and International Health, Universitat de Barcelona, Spain. He is also a professor at the Master in Clinical Epidemiology and Biostatistics, Universidad Científica del Sur, Lima, Peru. In 2021 he has been awarded the “Raul Isturiz Award” Medal of the API. Also, in 2021, he was awarded with the “Jose Felix Patiño” Asclepius Staff Medal of the Colombian Medical College, due to his scientific contributions to COVID-19 during the pandemic. He is currently the Editor in Chief of the journal Travel Medicine and Infectious Diseases. His Scopus H index is 47 (Google Scholar H index, 68).",institutionString:"Institución Universitaria Visión de las Américas, Colombia",institution:null},{id:"332819",title:"Dr.",name:"Chukwudi Michael",middleName:"Michael",surname:"Egbuche",slug:"chukwudi-michael-egbuche",fullName:"Chukwudi Michael Egbuche",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/332819/images/14624_n.jpg",biography:"I an Dr. Chukwudi Michael Egbuche. I am a Senior Lecturer in the Department of Parasitology and Entomology, Nnamdi Azikiwe University, Awka.",institutionString:null,institution:{name:"Nnamdi Azikiwe University",country:{name:"Nigeria"}}},{id:"284232",title:"Mr.",name:"Nikunj",middleName:"U",surname:"Tandel",slug:"nikunj-tandel",fullName:"Nikunj Tandel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/284232/images/8275_n.jpg",biography:'Mr. Nikunj Tandel has completed his Master\'s degree in Biotechnology from VIT University, India in the year of 2012. He is having 8 years of research experience especially in the field of malaria epidemiology, immunology, and nanoparticle-based drug delivery system against the infectious diseases, autoimmune disorders and cancer. He has worked for the NIH funded-International Center of Excellence in Malaria Research project "Center for the study of complex malaria in India (CSCMi)" in collaboration with New York University. The preliminary objectives of the study are to understand and develop the evidence-based tools and interventions for the control and prevention of malaria in different sites of the INDIA. Alongside, with the help of next-generation genomics study, the team has studied the antimalarial drug resistance in India. Further, he has extended his research in the development of Humanized mice for the study of liver-stage malaria and identification of molecular marker(s) for the Artemisinin resistance. At present, his research focuses on understanding the role of B cells in the activation of CD8+ T cells in malaria. Received the CSIR-SRF (Senior Research Fellow) award-2018, FIMSA (Federation of Immunological Societies of Asia-Oceania) Travel Bursary award to attend the IUIS-IIS-FIMSA Immunology course-2019',institutionString:"Nirma University",institution:{name:"Nirma University",country:{name:"India"}}},{id:"334383",title:"Ph.D.",name:"Simone",middleName:"Ulrich",surname:"Ulrich Picoli",slug:"simone-ulrich-picoli",fullName:"Simone Ulrich Picoli",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/334383/images/15919_n.jpg",biography:"Graduated in Pharmacy from Universidade Luterana do Brasil (1999), Master in Agricultural and Environmental Microbiology from Federal University of Rio Grande do Sul (2002), Specialization in Clinical Microbiology from Universidade de São Paulo, USP (2007) and PhD in Sciences in Gastroenterology and Hepatology (2012). She is currently an Adjunct Professor at Feevale University in Medicine and Biomedicine courses and a permanent professor of the Academic Master\\'s Degree in Virology. She has experience in the field of Microbiology, with an emphasis on Bacteriology, working mainly on the following topics: bacteriophages, bacterial resistance, clinical microbiology and food microbiology.",institutionString:null,institution:{name:"Universidade Feevale",country:{name:"Brazil"}}},{id:"229220",title:"Dr.",name:"Amjad",middleName:"Islam",surname:"Aqib",slug:"amjad-aqib",fullName:"Amjad Aqib",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229220/images/system/229220.png",biography:"Dr. Amjad Islam Aqib obtained a DVM and MSc (Hons) from University of Agriculture Faisalabad (UAF), Pakistan, and a PhD from the University of Veterinary and Animal Sciences Lahore, Pakistan. Dr. Aqib joined the Department of Clinical Medicine and Surgery at UAF for one year as an assistant professor where he developed a research laboratory designated for pathogenic bacteria. Since 2018, he has been Assistant Professor/Officer in-charge, Department of Medicine, Manager Research Operations and Development-ORIC, and President One Health Club at Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan. He has nearly 100 publications to his credit. His research interests include epidemiological patterns and molecular analysis of antimicrobial resistance and modulation and vaccine development against animal pathogens of public health concern.",institutionString:"Cholistan University of Veterinary and Animal Sciences",institution:null},{id:"62900",title:"Prof.",name:"Fethi",middleName:null,surname:"Derbel",slug:"fethi-derbel",fullName:"Fethi Derbel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/62900/images/system/62900.jpeg",biography:"Professor Fethi Derbel was born in 1960 in Tunisia. He received his medical degree from the Sousse Faculty of Medicine at Sousse, University of Sousse, Tunisia. He completed his surgical residency in General Surgery at the University Hospital Farhat Hached of Sousse and was a member of the Unit of Liver Transplantation in the University of Rennes, France. He then worked in the Department of Surgery at the Sahloul University Hospital in Sousse. Professor Derbel is presently working at the Clinique les Oliviers, Sousse, Tunisia. His hospital activities are mostly concerned with laparoscopic, colorectal, pancreatic, hepatobiliary, and gastric surgery. He is also very interested in hernia surgery and performs ventral hernia repairs and inguinal hernia repairs. He has been a member of the GREPA and Tunisian Hernia Society (THS). During his residency, he managed patients suffering from diabetic foot, and he was very interested in this pathology. For this reason, he decided to coordinate a book project dealing with the diabetic foot. Professor Derbel has published many articles in journals and collaborates intensively with IntechOpen Access Publisher as an editor.",institutionString:"Clinique les Oliviers",institution:null},{id:"300144",title:"Dr.",name:"Meriem",middleName:null,surname:"Braiki",slug:"meriem-braiki",fullName:"Meriem Braiki",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/300144/images/system/300144.jpg",biography:"Dr. Meriem Braiki is a specialist in pediatric surgeon from Tunisia. She was born in 1985. She received her medical degree from the University of Medicine at Sousse, Tunisia. She achieved her surgical residency training periods in Pediatric Surgery departments at University Hospitals in Monastir, Tunis and France.\r\nShe is currently working at the Pediatric surgery department, Sidi Bouzid Hospital, Tunisia. Her hospital activities are mostly concerned with laparoscopic, parietal, urological and digestive surgery. She has published several articles in diffrent journals.",institutionString:"Sidi Bouzid Regional Hospital",institution:null},{id:"229481",title:"Dr.",name:"Erika M.",middleName:"Martins",surname:"de Carvalho",slug:"erika-m.-de-carvalho",fullName:"Erika M. de Carvalho",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/229481/images/6397_n.jpg",biography:null,institutionString:null,institution:{name:"Oswaldo Cruz Foundation",country:{name:"Brazil"}}},{id:"186537",title:"Prof.",name:"Tonay",middleName:null,surname:"Inceboz",slug:"tonay-inceboz",fullName:"Tonay Inceboz",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/186537/images/system/186537.jfif",biography:"I was graduated from Ege University of Medical Faculty (Turkey) in 1988 and completed his Med. PhD degree in Medical Parasitology at the same university. I became an Associate Professor in 2008 and Professor in 2014. I am currently working as a Professor at the Department of Medical Parasitology at Dokuz Eylul University, Izmir, Turkey.\n\nI have given many lectures, presentations in different academic meetings. I have more than 60 articles in peer-reviewed journals, 18 book chapters, 1 book editorship.\n\nMy research interests are Echinococcus granulosus, Echinococcus multilocularis (diagnosis, life cycle, in vitro and in vivo cultivation), and Trichomonas vaginalis (diagnosis, PCR, and in vitro cultivation).",institutionString:"Dokuz Eylül University",institution:{name:"Dokuz Eylül University",country:{name:"Turkey"}}},{id:"71812",title:"Prof.",name:"Hanem Fathy",middleName:"Fathy",surname:"Khater",slug:"hanem-fathy-khater",fullName:"Hanem Fathy Khater",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/71812/images/1167_n.jpg",biography:"Prof. Khater is a Professor of Parasitology at Benha University, Egypt. She studied for her doctoral degree, at the Department of Entomology, College of Agriculture, Food and Natural Resources, University of Missouri, Columbia, USA. She has completed her Ph.D. degrees in Parasitology in Egypt, from where she got the award for “the best scientific Ph.D. dissertation”. She worked at the School of Biological Sciences, Bristol, England, the UK in controlling insects of medical and veterinary importance as a grant from Newton Mosharafa, the British Council. Her research is focused on searching of pesticides against mosquitoes, house flies, lice, green bottle fly, camel nasal botfly, soft and hard ticks, mites, and the diamondback moth as well as control of several parasites using safe and natural materials to avoid drug resistances and environmental contamination.",institutionString:null,institution:{name:"Banha University",country:{name:"Egypt"}}},{id:"99780",title:"Prof.",name:"Omolade",middleName:"Olayinka",surname:"Okwa",slug:"omolade-okwa",fullName:"Omolade Okwa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/99780/images/system/99780.jpg",biography:"Omolade Olayinka Okwa is presently a Professor of Parasitology at Lagos State University, Nigeria. She has a PhD in Parasitology (1997), an MSc in Cellular Parasitology (1992), and a BSc (Hons) Zoology (1990) all from the University of Ibadan, Nigeria. She teaches parasitology at the undergraduate and postgraduate levels. She was a recipient of a Commonwealth fellowship supported by British Council tenable at the Centre for Entomology and Parasitology (CAEP), Keele University, United Kingdom between 2004 and 2005. She was awarded an Honorary Visiting Research Fellow at the same university from 2005 to 2007. \nShe has been an external examiner to the Department of Veterinary Microbiology and Parasitology, University of Ibadan, MSc programme between 2010 and 2012. She is a member of the Nigerian Society of Experimental Biology (NISEB), Parasitology and Public Health Society of Nigeria (PPSN), Science Association of Nigeria (SAN), Zoological Society of Nigeria (ZSN), and is Vice Chairperson of the Organisation of Women in Science (OWSG), LASU chapter. She served as Head of Department of Zoology and Environmental Biology, Lagos State University from 2007 to 2010 and 2014 to 2016. She is a reviewer for several local and international journals such as Unilag Journal of Science, Libyan Journal of Medicine, Journal of Medicine and Medical Sciences, and Annual Research and Review in Science. \nShe has authored 45 scientific research publications in local and international journals, 8 scientific reviews, 4 books, and 3 book chapters, which includes the books “Malaria Parasites” and “Malaria” which are IntechOpen access publications.",institutionString:"Lagos State University",institution:{name:"Lagos State University",country:{name:"Nigeria"}}},{id:"273100",title:"Dr.",name:"Vijay",middleName:null,surname:"Gayam",slug:"vijay-gayam",fullName:"Vijay Gayam",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/273100/images/system/273100.jpeg",biography:"Dr. Vijay Bhaskar Reddy Gayam is currently practicing as an internist at Interfaith Medical Center in Brooklyn, New York, USA. He is also a Clinical Assistant Professor at the SUNY Downstate University Hospital and Adjunct Professor of Medicine at the American University of Antigua. He is a holder of an M.B.B.S. degree bestowed to him by Osmania Medical College and received his M.D. at Interfaith Medical Center. His career goals thus far have heavily focused on direct patient care, medical education, and clinical research. He currently serves in two leadership capacities; Assistant Program Director of Medicine at Interfaith Medical Center and as a Councilor for the American\r\nFederation for Medical Research. As a true academician and researcher, he has more than 50 papers indexed in international peer-reviewed journals. He has also presented numerous papers in multiple national and international scientific conferences. His areas of research interest include general internal medicine, gastroenterology and hepatology. He serves as an editor, editorial board member and reviewer for multiple international journals. His research on Hepatitis C has been very successful and has led to multiple research awards, including the 'Equity in Prevention and Treatment Award” from the New York Department of Health Viral Hepatitis Symposium (2018) and the 'Presidential Poster Award” awarded to him by the American College of Gastroenterology (2018). He was also awarded 'Outstanding Clinician in General Medicine” by Venus International Foundation for his extensive research expertise and services, perform over and above the standard expected in the advancement of healthcare, patient safety and quality of care.",institutionString:"Interfaith Medical Center",institution:{name:"Interfaith Medical Center",country:{name:"United States of America"}}},{id:"93517",title:"Dr.",name:"Clement",middleName:"Adebajo",surname:"Meseko",slug:"clement-meseko",fullName:"Clement Meseko",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/93517/images/system/93517.jpg",biography:"Dr. Clement Meseko obtained DVM and PhD degree in Veterinary Medicine and Virology respectively. He has worked for over 20 years in both private and public sectors including the academia, contributing to knowledge and control of infectious disease. Through the application of epidemiological skill, classical and molecular virological skills, he investigates viruses of economic and public health importance for the mitigation of the negative impact on people, animal and the environment in the context of Onehealth. \r\nDr. Meseko’s field experience on animal and zoonotic diseases and pathogen dynamics at the human-animal interface over the years shaped his carrier in research and scientific inquiries. He has been part of the investigation of Highly Pathogenic Avian Influenza incursions in sub Saharan Africa and monitors swine Influenza (Pandemic influenza Virus) agro-ecology and potential for interspecies transmission. He has authored and reviewed a number of journal articles and book chapters.",institutionString:"National Veterinary Research Institute",institution:{name:"National Veterinary Research Institute",country:{name:"Nigeria"}}},{id:"158026",title:"Prof.",name:"Shailendra K.",middleName:null,surname:"Saxena",slug:"shailendra-k.-saxena",fullName:"Shailendra K. Saxena",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRET3QAO/Profile_Picture_2022-05-10T10:10:26.jpeg",biography:"Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research work has been published in various high-impact factor journals (Science, PNAS, Nature Medicine) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by The Scientist. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).",institutionString:null,institution:{name:"King George's Medical University",country:{name:"India"}}},{id:"94928",title:"Dr.",name:"Takuo",middleName:null,surname:"Mizukami",slug:"takuo-mizukami",fullName:"Takuo Mizukami",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94928/images/6402_n.jpg",biography:null,institutionString:null,institution:{name:"National Institute of Infectious Diseases",country:{name:"Japan"}}},{id:"233433",title:"Dr.",name:"Yulia",middleName:null,surname:"Desheva",slug:"yulia-desheva",fullName:"Yulia Desheva",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/233433/images/system/233433.png",biography:"Dr. Yulia Desheva is a leading researcher at the Institute of Experimental Medicine, St. Petersburg, Russia. She is a professor in the Stomatology Faculty, St. Petersburg State University. She has expertise in the development and evaluation of a wide range of live mucosal vaccines against influenza and bacterial complications. Her research interests include immunity against influenza and COVID-19 and the development of immunization schemes for high-risk individuals.",institutionString:'Federal State Budgetary Scientific Institution "Institute of Experimental Medicine"',institution:null},{id:"238958",title:"Mr.",name:"Atamjit",middleName:null,surname:"Singh",slug:"atamjit-singh",fullName:"Atamjit Singh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/238958/images/6575_n.jpg",biography:null,institutionString:null,institution:null},{id:"333753",title:"Dr.",name:"Rais",middleName:null,surname:"Ahmed",slug:"rais-ahmed",fullName:"Rais Ahmed",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333753/images/20168_n.jpg",biography:null,institutionString:null,institution:null},{id:"252058",title:"M.Sc.",name:"Juan",middleName:null,surname:"Sulca",slug:"juan-sulca",fullName:"Juan Sulca",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/252058/images/12834_n.jpg",biography:null,institutionString:null,institution:null},{id:"191392",title:"Dr.",name:"Marimuthu",middleName:null,surname:"Govindarajan",slug:"marimuthu-govindarajan",fullName:"Marimuthu Govindarajan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/191392/images/5828_n.jpg",biography:"Dr. M. Govindarajan completed his BSc degree in Zoology at Government Arts College (Autonomous), Kumbakonam, and MSc, MPhil, and PhD degrees at Annamalai University, Annamalai Nagar, Tamil Nadu, India. He is serving as an assistant professor at the Department of Zoology, Annamalai University. His research interests include isolation, identification, and characterization of biologically active molecules from plants and microbes. He has identified more than 20 pure compounds with high mosquitocidal activity and also conducted high-quality research on photochemistry and nanosynthesis. He has published more than 150 studies in journals with impact factor and 2 books in Lambert Academic Publishing, Germany. He serves as an editorial board member in various national and international scientific journals.",institutionString:null,institution:null},{id:"274660",title:"Dr.",name:"Damodar",middleName:null,surname:"Paudel",slug:"damodar-paudel",fullName:"Damodar Paudel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/274660/images/8176_n.jpg",biography:"I am DrDamodar Paudel,currently working as consultant Physician in Nepal police Hospital.",institutionString:null,institution:null},{id:"241562",title:"Dr.",name:"Melvin",middleName:null,surname:"Sanicas",slug:"melvin-sanicas",fullName:"Melvin Sanicas",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241562/images/6699_n.jpg",biography:null,institutionString:null,institution:null},{id:"337446",title:"Dr.",name:"Maria",middleName:null,surname:"Zavala-Colon",slug:"maria-zavala-colon",fullName:"Maria Zavala-Colon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Puerto Rico, Medical Sciences Campus",country:{name:"United States of America"}}},{id:"338856",title:"Mrs.",name:"Nur Alvira",middleName:null,surname:"Pascawati",slug:"nur-alvira-pascawati",fullName:"Nur Alvira Pascawati",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universitas Respati Yogyakarta",country:{name:"Indonesia"}}},{id:"441116",title:"Dr.",name:"Jovanka M.",middleName:null,surname:"Voyich",slug:"jovanka-m.-voyich",fullName:"Jovanka M. Voyich",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Montana State University",country:{name:"United States of America"}}},{id:"330412",title:"Dr.",name:"Muhammad",middleName:null,surname:"Farhab",slug:"muhammad-farhab",fullName:"Muhammad Farhab",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Agriculture Faisalabad",country:{name:"Pakistan"}}},{id:"349495",title:"Dr.",name:"Muhammad",middleName:null,surname:"Ijaz",slug:"muhammad-ijaz",fullName:"Muhammad Ijaz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}}]}},subseries:{item:{id:"8",type:"subseries",title:"Bioinspired Technology and Biomechanics",keywords:"Bioinspired Systems, Biomechanics, Assistive Technology, Rehabilitation",scope:'Bioinspired technologies take advantage of understanding the actual biological system to provide solutions to problems in several areas. Recently, bioinspired systems have been successfully employing biomechanics to develop and improve assistive technology and rehabilitation devices. The research topic "Bioinspired Technology and Biomechanics" welcomes studies reporting recent advances in bioinspired technologies that contribute to individuals\' health, inclusion, and rehabilitation. Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",hasOnlineFirst:!1,hasPublishedBooks:!0,annualVolume:11404,editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",slug:"adriano-andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",biography:"Dr. Adriano de Oliveira Andrade graduated in Electrical Engineering at the Federal University of Goiás (Brazil) in 1997. He received his MSc and PhD in Biomedical Engineering respectively from the Federal University of Uberlândia (UFU, Brazil) in 2000 and from the University of Reading (UK) in 2005. He completed a one-year Post-Doctoral Fellowship awarded by the DFAIT (Foreign Affairs and International Trade Canada) at the Institute of Biomedical Engineering of the University of New Brunswick (Canada) in 2010. Currently, he is Professor in the Faculty of Electrical Engineering (UFU). He has authored and co-authored more than 200 peer-reviewed publications in Biomedical Engineering. He has been a researcher of The National Council for Scientific and Technological Development (CNPq-Brazil) since 2009. He has served as an ad-hoc consultant for CNPq, CAPES (Coordination for the Improvement of Higher Education Personnel), FINEP (Brazilian Innovation Agency), and other funding bodies on several occasions. He was the Secretary of the Brazilian Society of Biomedical Engineering (SBEB) from 2015 to 2016, President of SBEB (2017-2018) and Vice-President of SBEB (2019-2020). He was the head of the undergraduate program in Biomedical Engineering of the Federal University of Uberlândia (2015 - June/2019) and the head of the Centre for Innovation and Technology Assessment in Health (NIATS/UFU) since 2010. He is the head of the Postgraduate Program in Biomedical Engineering (UFU, July/2019 - to date). He was the secretary of the Parkinson's Disease Association of Uberlândia (2018-2019). Dr. Andrade's primary area of research is focused towards getting information from the neuromuscular system to understand its strategies of organization, adaptation and controlling in the context of motor neuron diseases. 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For example, some of the issues of interest could be the following: Advances in evolutionary computation (Genetic algorithms, Genetic programming, Bio-inspired metaheuristics, Hybrid metaheuristics, Parallel ECs); Applications of evolutionary algorithms (Machine learning and Data Mining with EAs, Search-Based Software Engineering, Scheduling, and Planning Applications, Smart Transport Applications, Applications to Games, Image Analysis, Signal Processing and Pattern Recognition, Applications to Sustainability).",coverUrl:"https://cdn.intechopen.com/series_topics/covers/25.jpg",keywords:"Genetic Algorithms, Genetic Programming, Evolutionary Programming, Evolution Strategies, Hybrid Algorithms, Bioinspired Metaheuristics, Ant Colony Optimization, Evolutionary Learning, Hyperparameter Optimization"},{id:"26",title:"Machine Learning and Data Mining",scope:"The scope of machine learning and data mining is immense and is growing every day. It has become a massive part of our daily lives, making predictions based on experience, making this a fascinating area that solves problems that otherwise would not be possible or easy to solve. This topic aims to encompass algorithms that learn from experience (supervised and unsupervised), improve their performance over time and enable machines to make data-driven decisions. It is not limited to any particular applications, but contributions are encouraged from all disciplines.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/26.jpg",keywords:"Intelligent Systems, Machine Learning, Data Science, Data Mining, Artificial Intelligence"},{id:"27",title:"Multi-Agent Systems",scope:"Multi-agent systems are recognised as a state of the art field in Artificial Intelligence studies, which is popular due to the usefulness in facilitation capabilities to handle real-world problem-solving in a distributed fashion. The area covers many techniques that offer solutions to emerging problems in robotics and enterprise-level software systems. Collaborative intelligence is highly and effectively achieved with multi-agent systems. Areas of application include swarms of robots, flocks of UAVs, collaborative software management. Given the level of technological enhancements, the popularity of machine learning in use has opened a new chapter in multi-agent studies alongside the practical challenges and long-lasting collaboration issues in the field. It has increased the urgency and the need for further studies in this field. We welcome chapters presenting research on the many applications of multi-agent studies including, but not limited to, the following key areas: machine learning for multi-agent systems; modeling swarms robots and flocks of UAVs with multi-agent systems; decision science and multi-agent systems; software engineering for and with multi-agent systems; tools and technologies of multi-agent systems.",coverUrl:"https://cdn.intechopen.com/series_topics/covers/27.jpg",keywords:"Collaborative Intelligence, Learning, Distributed Control System, Swarm Robotics, Decision Science, Software Engineering"}],annualVolumeBook:{},thematicCollection:[],selectedSeries:{title:"Artificial Intelligence",id:"14"},selectedSubseries:null},seriesLanding:{item:{id:"7",title:"Biomedical Engineering",doi:"10.5772/intechopen.71985",issn:"2631-5343",scope:"Biomedical Engineering is one of the fastest-growing interdisciplinary branches of science and industry. The combination of electronics and computer science with biology and medicine has improved patient diagnosis, reduced rehabilitation time, and helped to facilitate a better quality of life. Nowadays, all medical imaging devices, medical instruments, or new laboratory techniques result from the cooperation of specialists in various fields. The series of Biomedical Engineering books covers such areas of knowledge as chemistry, physics, electronics, medicine, and biology. This series is intended for doctors, engineers, and scientists involved in biomedical engineering or those wanting to start working in this field.",coverUrl:"https://cdn.intechopen.com/series/covers/7.jpg",latestPublicationDate:"May 7th, 2022",hasOnlineFirst:!0,numberOfOpenTopics:3,numberOfPublishedChapters:96,numberOfPublishedBooks:12,editor:{id:"50150",title:"Prof.",name:"Robert",middleName:null,surname:"Koprowski",fullName:"Robert Koprowski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTYNQA4/Profile_Picture_1630478535317",biography:"Robert Koprowski, MD (1997), PhD (2003), Habilitation (2015), is an employee of the University of Silesia, Poland, Institute of Computer Science, Department of Biomedical Computer Systems. For 20 years, he has studied the analysis and processing of biomedical images, emphasizing the full automation of measurement for a large inter-individual variability of patients. Dr. Koprowski has authored more than a hundred research papers with dozens in impact factor (IF) journals and has authored or co-authored six books. Additionally, he is the author of several national and international patents in the field of biomedical devices and imaging. Since 2011, he has been a reviewer of grants and projects (including EU projects) in biomedical engineering.",institutionString:null,institution:{name:"University of Silesia",institutionURL:null,country:{name:"Poland"}}},subseries:[{id:"7",title:"Bioinformatics and Medical Informatics",keywords:"Biomedical Data, Drug Discovery, Clinical Diagnostics, Decoding Human Genome, AI in Personalized Medicine, Disease-prevention Strategies, Big Data Analysis in Medicine",scope:"Bioinformatics aims to help understand the functioning of the mechanisms of living organisms through the construction and use of quantitative tools. The applications of this research cover many related fields, such as biotechnology and medicine, where, for example, Bioinformatics contributes to faster drug design, DNA analysis in forensics, and DNA sequence analysis in the field of personalized medicine. Personalized medicine is a type of medical care in which treatment is customized individually for each patient. Personalized medicine enables more effective therapy, reduces the costs of therapy and clinical trials, and also minimizes the risk of side effects. Nevertheless, advances in personalized medicine would not have been possible without bioinformatics, which can analyze the human genome and other vast amounts of biomedical data, especially in genetics. The rapid growth of information technology enabled the development of new tools to decode human genomes, large-scale studies of genetic variations and medical informatics. The considerable development of technology, including the computing power of computers, is also conducive to the development of bioinformatics, including personalized medicine. In an era of rapidly growing data volumes and ever lower costs of generating, storing and computing data, personalized medicine holds great promises. Modern computational methods used as bioinformatics tools can integrate multi-scale, multi-modal and longitudinal patient data to create even more effective and safer therapy and disease prevention methods. Main aspects of the topic are: Applying bioinformatics in drug discovery and development; Bioinformatics in clinical diagnostics (genetic variants that act as markers for a condition or a disease); Blockchain and Artificial Intelligence/Machine Learning in personalized medicine; Customize disease-prevention strategies in personalized medicine; Big data analysis in personalized medicine; Translating stratification algorithms into clinical practice of personalized medicine.",annualVolume:11403,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/7.jpg",editor:{id:"351533",title:"Dr.",name:"Slawomir",middleName:null,surname:"Wilczynski",fullName:"Slawomir Wilczynski",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000035U1loQAC/Profile_Picture_1630074514792",institutionString:null,institution:{name:"Medical University of Silesia",institutionURL:null,country:{name:"Poland"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"5886",title:"Dr.",name:"Alexandros",middleName:"T.",surname:"Tzallas",fullName:"Alexandros Tzallas",profilePictureURL:"https://mts.intechopen.com/storage/users/5886/images/system/5886.png",institutionString:"University of Ioannina, Greece & Imperial College London",institution:{name:"University of Ioannina",institutionURL:null,country:{name:"Greece"}}},{id:"257388",title:"Distinguished Prof.",name:"Lulu",middleName:null,surname:"Wang",fullName:"Lulu Wang",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRX6kQAG/Profile_Picture_1630329584194",institutionString:null,institution:{name:"Shenzhen Technology University",institutionURL:null,country:{name:"China"}}},{id:"225387",title:"Prof.",name:"Reda",middleName:"R.",surname:"Gharieb",fullName:"Reda Gharieb",profilePictureURL:"https://mts.intechopen.com/storage/users/225387/images/system/225387.jpg",institutionString:"Assiut University",institution:{name:"Assiut University",institutionURL:null,country:{name:"Egypt"}}}]},{id:"8",title:"Bioinspired Technology and Biomechanics",keywords:"Bioinspired Systems, Biomechanics, Assistive Technology, Rehabilitation",scope:'Bioinspired technologies take advantage of understanding the actual biological system to provide solutions to problems in several areas. Recently, bioinspired systems have been successfully employing biomechanics to develop and improve assistive technology and rehabilitation devices. The research topic "Bioinspired Technology and Biomechanics" welcomes studies reporting recent advances in bioinspired technologies that contribute to individuals\' health, inclusion, and rehabilitation. Possible contributions can address (but are not limited to) the following research topics: Bioinspired design and control of exoskeletons, orthoses, and prostheses; Experimental evaluation of the effect of assistive devices (e.g., influence on gait, balance, and neuromuscular system); Bioinspired technologies for rehabilitation, including clinical studies reporting evaluations; Application of neuromuscular and biomechanical models to the development of bioinspired technology.',annualVolume:11404,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/8.jpg",editor:{id:"144937",title:"Prof.",name:"Adriano",middleName:"De Oliveira",surname:"Andrade",fullName:"Adriano Andrade",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRC8QQAW/Profile_Picture_1625219101815",institutionString:null,institution:{name:"Federal University of Uberlândia",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"49517",title:"Prof.",name:"Hitoshi",middleName:null,surname:"Tsunashima",fullName:"Hitoshi Tsunashima",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYTP4QAO/Profile_Picture_1625819726528",institutionString:null,institution:{name:"Nihon University",institutionURL:null,country:{name:"Japan"}}},{id:"425354",title:"Dr.",name:"Marcus",middleName:"Fraga",surname:"Vieira",fullName:"Marcus Vieira",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003BJSgIQAX/Profile_Picture_1627904687309",institutionString:null,institution:{name:"Universidade Federal de Goiás",institutionURL:null,country:{name:"Brazil"}}},{id:"196746",title:"Dr.",name:"Ramana",middleName:null,surname:"Vinjamuri",fullName:"Ramana Vinjamuri",profilePictureURL:"https://mts.intechopen.com/storage/users/196746/images/system/196746.jpeg",institutionString:"University of Maryland, Baltimore County",institution:{name:"University of Maryland, Baltimore County",institutionURL:null,country:{name:"United States of America"}}}]},{id:"9",title:"Biotechnology - Biosensors, Biomaterials and Tissue Engineering",keywords:"Biotechnology, Biosensors, Biomaterials, Tissue Engineering",scope:"The Biotechnology - Biosensors, Biomaterials and Tissue Engineering topic within the Biomedical Engineering Series aims to rapidly publish contributions on all aspects of biotechnology, biosensors, biomaterial and tissue engineering. We encourage the submission of manuscripts that provide novel and mechanistic insights that report significant advances in the fields. Topics can include but are not limited to: Biotechnology such as biotechnological products and process engineering; Biotechnologically relevant enzymes and proteins; Bioenergy and biofuels; Applied genetics and molecular biotechnology; Genomics, transcriptomics, proteomics; Applied microbial and cell physiology; Environmental biotechnology; Methods and protocols. Moreover, topics in biosensor technology, like sensors that incorporate enzymes, antibodies, nucleic acids, whole cells, tissues and organelles, and other biological or biologically inspired components will be considered, and topics exploring transducers, including those based on electrochemical and optical piezoelectric, thermal, magnetic, and micromechanical elements. Chapters exploring biomaterial approaches such as polymer synthesis and characterization, drug and gene vector design, biocompatibility, immunology and toxicology, and self-assembly at the nanoscale, are welcome. Finally, the tissue engineering subcategory will support topics such as the fundamentals of stem cells and progenitor cells and their proliferation, differentiation, bioreactors for three-dimensional culture and studies of phenotypic changes, stem and progenitor cells, both short and long term, ex vivo and in vivo implantation both in preclinical models and also in clinical trials.",annualVolume:11405,isOpenForSubmission:!0,coverUrl:"https://cdn.intechopen.com/series_topics/covers/9.jpg",editor:{id:"126286",title:"Dr.",name:"Luis",middleName:"Jesús",surname:"Villarreal-Gómez",fullName:"Luis Villarreal-Gómez",profilePictureURL:"https://mts.intechopen.com/storage/users/126286/images/system/126286.jpg",institutionString:null,institution:{name:"Autonomous University of Baja California",institutionURL:null,country:{name:"Mexico"}}},editorTwo:null,editorThree:null,editorialBoard:[{id:"35539",title:"Dr.",name:"Cecilia",middleName:null,surname:"Cristea",fullName:"Cecilia Cristea",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYQ65QAG/Profile_Picture_1621007741527",institutionString:null,institution:{name:"Iuliu Hațieganu University of Medicine and Pharmacy",institutionURL:null,country:{name:"Romania"}}},{id:"40735",title:"Dr.",name:"Gil",middleName:"Alberto Batista",surname:"Gonçalves",fullName:"Gil Gonçalves",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYRLGQA4/Profile_Picture_1628492612759",institutionString:null,institution:{name:"University of Aveiro",institutionURL:null,country:{name:"Portugal"}}},{id:"211725",title:"Associate Prof.",name:"Johann F.",middleName:null,surname:"Osma",fullName:"Johann F. Osma",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSDv7QAG/Profile_Picture_1626602531691",institutionString:null,institution:{name:"Universidad de Los Andes",institutionURL:null,country:{name:"Colombia"}}},{id:"69697",title:"Dr.",name:"Mani T.",middleName:null,surname:"Valarmathi",fullName:"Mani T. Valarmathi",profilePictureURL:"https://mts.intechopen.com/storage/users/69697/images/system/69697.jpg",institutionString:"Religen Inc. | A Life Science Company, United States of America",institution:null},{id:"205081",title:"Dr.",name:"Marco",middleName:"Vinícius",surname:"Chaud",fullName:"Marco Chaud",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSDGeQAO/Profile_Picture_1622624307737",institutionString:null,institution:{name:"Universidade de Sorocaba",institutionURL:null,country:{name:"Brazil"}}}]}]}},libraryRecommendation:{success:null,errors:{},institutions:[]},route:{name:"profile.detail",path:"/profiles/420530",hash:"",query:{},params:{id:"420530"},fullPath:"/profiles/420530",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()