Ota Fuchs

Institute of Hematology and Blood Transfusion

Ota Fuchs graduated from the Chemical Technological University, Prague, Czech Republic in 1971. He obtained his PhD in Biochemistry from the Faculty of Natural Sciences, Charles University, Prague in 1981. He is currently employed as a Senior Scientist at the Institute of Hematology and Blood Transfusion, Prague. He has undertaken, as a visiting scientist, short-term affiliations in the Beatson Institute for Cancer Research, Glasgow, UK; Institute of Experimental Medicine of the Russian Academy of Medical Sciences in St Peterburg, Russia; and in the Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada. He was principal investigator of five projects for the Internal Grant Agency of Ministry of Health of Czech Republic and of one grant project for the Grant Agency of Czech Republic.

3books edited

5chapters authored

Latest work with IntechOpen by Ota Fuchs

The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness.

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