Maria Marinescu

University of Bucharest

Maria Marinescu received her PhD in 2010 from the University of Bucharest, under the supervision of Prof. Mihaela Hillebrand, studying the chemistry and the electronic structure of the 1,2,3,4,5,6,7,8-octahydroacridine compounds, as a key structures for the new biomolecules and hydrogen-bonding receptors. Dr Maria Marinescu is currently an Assistant Professor at the University of Bucharest, Department of Organic Chemistry, Biochemistry and Catalysis and her current research interests are in organic synthesis of various heterocycles with applications in medicinal and materials chemistry, DFT studies in organic molecules related with their biological properties and applications of organic materials in art and archaeology.

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Finding new strategies for synthesizing benzimidazole derivatives and functionalizing the benzimidazole core has proved to be important due to the compound's various applications in medicine, chemistry, and other areas. The multitude of benzimidazole derivatives marketed as drugs has led to intensive research in the field for the discovery of new biologically active structures. The general applications of benzimidazole derivatives in materials chemistry, electronics, technology, dyes, pigments, and agriculture open up new research horizons. This book guides the rational design of benzimidazole derivatives synthesis with certain applications. Chapters cover such topics as therapeutic use of benzimidazole in conditions like diabetes, viruses, and parasitic diseases; X-ray crystal structure of selected benzimidazole derivatives; benzimidazole compounds for cancer therapy; and others.

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