CPFA food sources.
\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"5140",leadTitle:null,fullTitle:"Tourism - From Empirical Research Towards Practical Application",title:"Tourism",subtitle:"From Empirical Research Towards Practical Application",reviewType:"peer-reviewed",abstract:"Tourism is that area of activity of contemporary man that touches on various fields of human interest. Representatives of numerous academic disciplines find it intriguing for its exceptionally interdisciplinary character. Conditions for and consequences of the development of tourism are investigated, among others, by economists, geographers, sociologists, experts in culture, anthropologists, management and social policy specialists and even by representatives of some natural sciences. Researchers dealing with tourism need to meet strict methodological requirements, but they get access to a very interesting subject of scientific inquiry, which combines social, cultural, economic and environmental aspects to create an ontologically new quality offering epistemological challenges.",isbn:"978-953-51-2281-4",printIsbn:null,pdfIsbn:"978-953-51-4202-7",doi:"10.5772/61385",price:119,priceEur:129,priceUsd:155,slug:"tourism-from-empirical-research-towards-practical-application",numberOfPages:192,isOpenForSubmission:!1,isInWos:1,isInBkci:!0,hash:"531b164332e7b0e0ddd2fee58d50823e",bookSignature:"Leszek Butowski",publishedDate:"May 4th 2016",coverURL:"https://cdn.intechopen.com/books/images_new/5140.jpg",numberOfDownloads:26510,numberOfWosCitations:70,numberOfCrossrefCitations:46,numberOfCrossrefCitationsByBook:1,numberOfDimensionsCitations:87,numberOfDimensionsCitationsByBook:1,hasAltmetrics:1,numberOfTotalCitations:203,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"September 23rd 2015",dateEndSecondStepPublish:"October 14th 2015",dateEndThirdStepPublish:"January 18th 2016",dateEndFourthStepPublish:"April 17th 2016",dateEndFifthStepPublish:"June 15th 2016",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,8",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"114047",title:"Ph.D.",name:"Leszek",middleName:null,surname:"Butowski",slug:"leszek-butowski",fullName:"Leszek Butowski",profilePictureURL:"https://mts.intechopen.com/storage/users/114047/images/4556_n.png",biography:"Leszek Butowski is a professor of Tourism and Geography at the University of Lodz (Poland). He received a PhD degree from the University of Warsaw and a habilitation degree from the University of Maria Skłodowska Curie. He also completed his postgraduate study on International Tourism at the University Paris 1 Panthéon-Sorbonne. Professor Butowski has cooperated with many Polish and European institutions on different issues connected with tourism development. He teaches at the undergraduate, graduate, and doctorate levels, focusing on methodological foundations of tourism research as well as sustainability in tourism development. His interests revolve in particular around nautical tourism. Leszek Butowski has given lectures at many universities in Poland, Turkey, Cyprus, and Portugal. Apart from academic work, his passion is yachting, and each summer he sails the European waters on his small, classic cutter named “Lideczka” (diminutive form of Lidia).",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"Lodz University of Technology",institutionURL:null,country:{name:"Poland"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"462",title:"Tourism Development",slug:"hospitality-management-tourism-development"}],chapters:[{id:"50032",title:"Community Participation toward Tourism Development and Conservation Program in Rural World Heritage Sites",doi:"10.5772/62293",slug:"community-participation-toward-tourism-development-and-conservation-program-in-rural-world-heritage-",totalDownloads:5090,totalCrossrefCites:12,totalDimensionsCites:20,hasAltmetrics:1,abstract:"Community participation in tourism development and World Heritage Site (WHS) conservation management is essential for the sustainable development of WHS destinations. Local communities play a significant role in reviving and sustaining WHSs. Community participation ranges from involvement in the decision-making processes at the highest level down to economic involvement and the promotion of the destination at the lowest level. What shape community participation ultimately takes depends on the circumstance of destinations. This study attempts to review the current community participation literature with respect to rural WHS destinations, synthesising the current literature by way of a systematic review. The findings reveal a preference among rural WHS residents for economic involvement and destination promotion rather than participation in the decision-making process. The findings of this study expand upon the community participation literature, clarifying the concept in the context of rural WHS destinations. In addition, the results have practical implications for local authorities responsible for the sustainable conservation management and tourism development of rural WHS—that these seemingly competing objectives are best achieved by involving local residents in economic activities and increasing their benefits from tourism.",signatures:"S. Mostafa Rasoolimanesh and Mastura Jaafar",downloadPdfUrl:"/chapter/pdf-download/50032",previewPdfUrl:"/chapter/pdf-preview/50032",authors:[{id:"170959",title:"Dr.",name:"Mastura",surname:"Jaafar",slug:"mastura-jaafar",fullName:"Mastura Jaafar"},{id:"178812",title:"Dr.",name:"S. Mostafa",surname:"Rasoolimanesh",slug:"s.-mostafa-rasoolimanesh",fullName:"S. Mostafa Rasoolimanesh"}],corrections:null},{id:"50191",title:"Community Development Strategies for Tourism Development in Langkawi Islands, Malaysia",doi:"10.5772/62575",slug:"community-development-strategies-for-tourism-development-in-langkawi-islands-malaysia",totalDownloads:2287,totalCrossrefCites:0,totalDimensionsCites:2,hasAltmetrics:1,abstract:"Community capacity building is widely acknowledged as a crucial tool to foster the process of tourism development. In Langkawi, rapid transformation of the island leads to the marginalisation of the rural economy. As a result, various strategies and tools have been attempted to empower local community participation in tourism activities. This article aims to examine the existing strategies adopted by related stakeholders in Langkawi to work with local communities. For this purpose, in-depth semi-structured interviews were conducted among 20 local stakeholders including government and non-governmental agencies, community leaders, and tourism business operators. Results of the interviews indicated that the existing strategies and tools of capacity building approach include (1) education and training, (2) small and medium-sized enterprises (SMEs) projects, (3) environmental conservation strategies, and (4) partnership building. In conclusion, related authorities and tourism planners need to consider local residents' opinions into the implementation process to ensure positive outcomes from the community development strategies.",signatures:"Azizan Marzuki and Joanne Khoo",downloadPdfUrl:"/chapter/pdf-download/50191",previewPdfUrl:"/chapter/pdf-preview/50191",authors:[{id:"111261",title:"Associate Prof.",name:"Azizan",surname:"Marzuki",slug:"azizan-marzuki",fullName:"Azizan Marzuki"},{id:"184990",title:"Ms.",name:"Joanne",surname:"Khoo",slug:"joanne-khoo",fullName:"Joanne Khoo"}],corrections:null},{id:"50197",title:"Ecotourism and Its Role in Sustainable Development of Nepal",doi:"10.5772/62308",slug:"ecotourism-and-its-role-in-sustainable-development-of-nepal",totalDownloads:5023,totalCrossrefCites:7,totalDimensionsCites:14,hasAltmetrics:1,abstract:"Ecotourism helps in environmental protection, wildlife conservation, poverty alleviation and socio-economic development. It affects environmental, social and economic components of the community and the whole country. It has different forms which are named according to the preference of the country. Developed as well as developing countries , such as Nepal, are promoting ecotourism for sustainable development of the nation. Different methodologies are applied throughout the world by different researchers for assessing ecotourism. This chapter focuses on review of ecotourism researches throughout the world. It has both positive and negative impacts on environmental, social and economic aspects of the country. Due to the high rate of beneficial impacts, it is helping in the overall development of the community, country and the whole world. There is need of cooperation among different stakeholders, training of ecotourism to tourism entrepreneurs and appropriate management policy for sustainable implementation of ecotourism projects.",signatures:"Anup K. C.",downloadPdfUrl:"/chapter/pdf-download/50197",previewPdfUrl:"/chapter/pdf-preview/50197",authors:[{id:"178579",title:"Mr.",name:"Anup",surname:"K.C.",slug:"anup-k.c.",fullName:"Anup K.C."}],corrections:null},{id:"50364",title:"Tourism Carrying Capacity for Beaches of South Andaman Island, India",doi:"10.5772/62724",slug:"tourism-carrying-capacity-for-beaches-of-south-andaman-island-india",totalDownloads:3037,totalCrossrefCites:4,totalDimensionsCites:7,hasAltmetrics:0,abstract:"The Andaman and Nicobar Islands (ANI) is one of the largest tourist areas in India attracting both the international and domestic tourists each year. The Island Administration has a vision to develop the islands as an upmarket island destination for ecotourism. Among the island group, the South Andaman region is the most visited tourist destination and beaches of these islands have great potential for tourism attractions. The present work is an attempt to understand the potential of these beaches by assessing the carrying capacity in terms of number of visitors that can be allowed over a period of time, which will further help with better tourism management. The methodology used to estimate the tourism carrying capacity (TCC) is based on the physical and ecological conditions of each site and the existing infrastructure. The total effective carrying capacity (ECC) estimated for the beaches of Port Blair area (126,301 visitors/day) reveals that the current tourism activity is in lower level compared to its carrying capacity. Such carrying capacity assessments can be used as an input into the regular planning process. Preliminary estimates suggest that A&N Islands can be promoted for high value-low volume, eco-friendly, and environmentally sustainable tourism.",signatures:"R. Sridhar, E. Yuvaraj, V. Sachithanandam, T. Mageswaran, R.\nPurvaja and R. Ramesh",downloadPdfUrl:"/chapter/pdf-download/50364",previewPdfUrl:"/chapter/pdf-preview/50364",authors:[{id:"178784",title:"Dr.",name:"Sridhar",surname:"Rengarajan",slug:"sridhar-rengarajan",fullName:"Sridhar Rengarajan"},{id:"187060",title:"Mr.",name:"Yuvaraji",surname:"Eswaran",slug:"yuvaraji-eswaran",fullName:"Yuvaraji Eswaran"},{id:"187061",title:"Dr.",name:"Sachithanandam",surname:"Veeraragavan",slug:"sachithanandam-veeraragavan",fullName:"Sachithanandam Veeraragavan"},{id:"187062",title:"Dr.",name:"Mageswaran",surname:"Thangaraj",slug:"mageswaran-thangaraj",fullName:"Mageswaran Thangaraj"},{id:"187063",title:"Dr.",name:"Purvaja",surname:"Ramachandran",slug:"purvaja-ramachandran",fullName:"Purvaja Ramachandran"},{id:"187064",title:"Dr.",name:"Ramesh",surname:"Ramachandran",slug:"ramesh-ramachandran",fullName:"Ramesh Ramachandran"}],corrections:null},{id:"50165",title:"Assessing Potential Areas of Ecotourism through a Case Study in Ilgaz Mountain National Park",doi:"10.5772/62573",slug:"assessing-potential-areas-of-ecotourism-through-a-case-study-in-ilgaz-mountain-national-park",totalDownloads:2896,totalCrossrefCites:19,totalDimensionsCites:32,hasAltmetrics:1,abstract:"The changing demands of tourism provide greater benefits to tourists and generate competitive advantages that develop diversity in tourism. Elements of ecotourism fit within this context, and such tourism includes, but is not limited to, activities such as visiting natural and cultural resources without destroying nature, which are carried out with an aim toward sustainability. Ilgaz Mountain has a wealth of natural, cultural, historical, and recreational features, and its location near the Black Sea gives the area significant tourism potential. In order to evaluate the impact, potential, and possibilities of ecotourism in this protected area, we used geographic information systems (GIS) to determine the nature of protection required based on implementation availability. In this study, we used ecology-based identification of the natural and cultural values to characterize the features. The study consists of four parts: (1) the concept of ecotourism, (2) discussion of sustainable growth of tourism, (3) sustainability of ecotourism using GIS and how this is related to sustainable ecotourism in protected areas, such as in Turkey, (4) results and evaluation. By assessing these results, we aim to determine potential areas for ecotourism in terms of sustainable development, and we expect the results to provide useful ideas for further research.",signatures:"Mehmet Cetin and Hakan Sevik",downloadPdfUrl:"/chapter/pdf-download/50165",previewPdfUrl:"/chapter/pdf-preview/50165",authors:[{id:"93082",title:"Dr.",name:"Hakan",surname:"Sevik",slug:"hakan-sevik",fullName:"Hakan Sevik"},{id:"178455",title:"Ph.D.",name:"Mehmet",surname:"Cetin",slug:"mehmet-cetin",fullName:"Mehmet Cetin"}],corrections:null},{id:"50140",title:"Tourism, Competitiveness and Economic Growth: A New Analytical Model",doi:"10.5772/62276",slug:"tourism-competitiveness-and-economic-growth-a-new-analytical-model",totalDownloads:2890,totalCrossrefCites:2,totalDimensionsCites:5,hasAltmetrics:0,abstract:"This study reviews the theories relating to competitiveness and the indicators used for its measurement on the one hand and the studies that relate tourism and growth on the other, with the purpose of establishing the links that exist between both concepts. This enables a model to be defined in which some factors that affect tourism competitiveness combine with capital and work to determine economic growth. The provision of inherited tourism resources, together with the provision of productive resources, and the links between them are the determining elements of the capacity of an economy to produce and therefore to grow.",signatures:"María del P. Pablo-Romero, Palma Gómez-Calero and Javier\nSánchez-Rivas",downloadPdfUrl:"/chapter/pdf-download/50140",previewPdfUrl:"/chapter/pdf-preview/50140",authors:[{id:"72663",title:"Dr.",name:"Maria Del",surname:"Pablo-Romero",slug:"maria-del-pablo-romero",fullName:"Maria Del Pablo-Romero"},{id:"184221",title:"Dr.",name:"Palma",surname:"Gómez-Calero",slug:"palma-gomez-calero",fullName:"Palma Gómez-Calero"},{id:"184222",title:"Prof.",name:"Javier",surname:"Sanchez-Rivas",slug:"javier-sanchez-rivas",fullName:"Javier Sanchez-Rivas"}],corrections:null},{id:"50292",title:"Interaction between Cultural/Creative Tourism and Tourism/ Cultural Heritage Industries",doi:"10.5772/62661",slug:"interaction-between-cultural-creative-tourism-and-tourism-cultural-heritage-industries",totalDownloads:3359,totalCrossrefCites:2,totalDimensionsCites:7,hasAltmetrics:0,abstract:"The chapter presents a review of the conceptions of cultural and creative tourism, their resources, objectives and their benefit and damage to the nature and the society. It is very important in the postmodern society to not only develop cultural tourism that is one of the most rapidly growing branches of economy, but also to employ cultural heritage and does not always develop the common heritage and tourism industry. This is an especially sore point because the common cultural heritage and tourism industry has an opportunity to create added financial value for cities, regions, and it also develops a responsible conserving cultural tourist. Creative tourism is different from cultural tourism in that it provides tourists with experiences through their direct participation in offered tourism activities. Another idiosyncratic feature is that creative tourism travel packs are created by not only tourism organisations, but also communities that have authentic tangible and intangible heritage. It is important to note that cultural tourism can transform into creative tourism. Heritage tourism is of great importance as well because it relates to the aforementioned types of tourism. ‘Red’ tourism can be distinguished as a type of heritage tourism that attracts tourists’ attention.",signatures:"Dr. Jurėnienė Virginija",downloadPdfUrl:"/chapter/pdf-download/50292",previewPdfUrl:"/chapter/pdf-preview/50292",authors:[{id:"178530",title:"Dr.",name:"Jureniene",surname:"Virginija",slug:"jureniene-virginija",fullName:"Jureniene Virginija"}],corrections:null},{id:"50242",title:"Tourism and Immigration: The European Contribution to the Invention of Landscape and Hotel Industry in the Atacama Desert During the Nitrate Epoch, 1880–1930",doi:"10.5772/62640",slug:"tourism-and-immigration-the-european-contribution-to-the-invention-of-landscape-and-hotel-industry-i",totalDownloads:1928,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"This paper deals with the relation between European immigration and tourism industry in Atacama Desert. The period studied ranges from 1880 to 1930, coinciding with the greatest boom of the nitrate industry in Chile until the great nitrate crisis and world depression. Europeans arrived in Antofagasta Region between 1895 and 1920, developing different productive activities related to the nitrate exploitation and business, mainly by British, German, and Yugoslavian immigrants, and to a lesser extent by Spanish and Italians. The lodging industry, from hotels to boarding houses, grew tremendously owing to constant migration flows, both European and Latin American. As recreation sites were discovered on the coast, along with unexplored spaces in the hinterland, the possibility of a tourist landscape emerged and sustained by various European photo studios. The publicity of these recreation places was accompanied by gastronomy data and transportation by sea and earth, through different business guides issued since 1894.",signatures:"José Antonio González Pizarro",downloadPdfUrl:"/chapter/pdf-download/50242",previewPdfUrl:"/chapter/pdf-preview/50242",authors:[{id:"109954",title:"Dr.",name:"Jose A.",surname:"Gonzalez",slug:"jose-a.-gonzalez",fullName:"Jose A. 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Through these actions, dietary lipids can affect health, well-being, and the risk of developing disease, such as cardiovascular, inflammatory, and cognitive disorders, among many others [2].
The term lipid is known to describe fatty acids, their esters, and different lipophilic structures. Most dietary lipids consist of triglycerides, but there is also little amount of other lipid classes, such as phospholipids, present in the cell membranes of all food that we eat [3].
Fatty acids (FA) are carboxylic acids with an aliphatic chain of varying lengths: short chain (C < 6), medium chain (6C-12C), long chain (13C-22C), and very long chain (C > 22). The most common chain length range for fatty acids is between C12 and C22 and they can be characterized by saturated and unsaturated (mono or poly) chains [4]. Most of the FA existing in nature have an even number of carbon atoms and linear hydrocarbon chains, although some of them, found primarily in bacteria, may contain branched or cyclic structures [5, 6, 7]. Fatty acids containing a carbocyclic unit naturally occur in specific genera of bacteria and in plants.
In some cases, alicyclic fatty acids, such as cyclopropane (CPFA) and omega-cyclohexyl fatty acids (CHFA), are essential for cell survival, as they could affect the membrane fluidity that enables certain microorganisms to survive under extreme environmental conditions [8]. In plants, CPFA are usually minor components, where cyclopropene fatty acids are the most abundant.
CPFA, especially dihydrosterculic (9,10-methylene-octadecanoic acid) and lactobacillic (11,12-methylene-octadecanoic acid) acids, have been identified as minor component of lipid profile in a wide range of milk and dairy products [10, 11] and, more recently, in meat and fish [12] representing important foodstuffs in human diet.
CPFA concentration ranges from 200 to 1000 mg/kg fat in dairy products and bovine meat [13]; therefore, their dietary intake may not be negligible, and their potential role in human health should not be underestimated.
However, due to their recent identification, so far CPFA have not been yet considered for their occurrence in humans, and several aspects related to their bioavailability and putative bioactivity as well as the bacterial strains producing CPFA in feeds and in which conditions still must be explored.
ω-Cyclohexyl fatty acids (CHFAs), mainly cyclohexyl-undecanoic and tridecanoic acids, occur in several acido-thermophilic bacteria such as
This chapter reviews the literature data about the origin and natural occurrence of cyclic fatty acids, their presence in foods, especially in meat and dairy products, and their potential bioavailability and bioactivity in mammals. Finally, the application of some cyclic fatty acids as molecular markers for food authenticity will be provided.
Cyclopropane fatty acids (CPFA), containing three carbon rings located at different sites of the fatty acid chain (Figure 1), occur widespread in several microorganisms as major lipid component [8] and in certain eukaryotes, including protozoa, fungi, and plants [9, 15]. Many cyclopropane-containing natural compounds have shown biological activity, and their presence in the cellular membrane seems to be related to its physicochemical properties [16]. However, the real significance of these compounds in their natural context is often less well known as well as their occurrence in higher animals. The major investigations which have beenpublished about their occurrence, biosynthesis, and their physiological role in the cellular membrane are described in more detail in the following paragraphs.
Most commonly found cyclopropane fatty acids in bacteria.
A study of the fatty acid composition of
Subsequently, lactobacillic acid and other cyclopropane fatty acids have been identified in a variety of microorganisms of both Gram-negative and Gram-positive bacteria such as Lactobacilli, Streptococci, Enterobacteria, Clostridia, and Brucellaceae [18]. Some microorganisms contain cis-9,10-methylene octadecanoic acid (dihydrosterculic acid), derived from oleic acid, together with other isomers (C16 or C20 in chain length, as cis-9,10-methylene hexadecenoic acid).
CPFA are suggested to be associated with the occurrence of unsaturated fatty acids (UFA) in the bacterial membrane, generally palmitoleic (cis-9-hexadecenoic acid), cis-vaccenic (cis-11-octadecenoic acid), and oleic (cis-9-octadecenoic acid) acids [5]. Furthermore, it seems that they predominate at the end of the growth cycle of bacteria, when the majority of UFA are converted to cyclopropane fatty acids by the cyclopropane synthase [8].
Cyclopropane and the structurally related cyclopropene fatty acids have also been found in certain eukaryotes, including trypanosomatid protozoa and plants [19, 20].
In plants, cyclopropene fatty acids, such as sterculic acid (cis-9,10-methylene-9-octadecenoic acid) and malvalic acid (cis-8,9-methylene-heptadecenoic acid), are distributed across several families, mainly in Sterculiaceae, Malvaceae, Bombacaceae, Tiliaceae, and Sapindaceae. It has been reported that cyclopropene fatty acids are often accompanied by smaller proportion of cyclopropanic fatty acids, such as dihydrosterculic and dihydromalvalic acids, which are the dihydro analogues of cyclopropene fatty acids [21].
CPFA were the major lipid component (42%) in the seed oil of
Malvalic, sterculic, and dihydrosterculic acids have also been detected in Baobab seeds oil from plant belonging to Adansonia species (Bombacaceae family) of Madagascar. Seed lipids containing CPFA are extensively consumed by humans, especially in those tropical areas [19, 23].
However, carbocyclic fatty acids seemed not to be confined to seeds. Long-chain cyclopropane fatty acids have been described in various polar lipid classes of leaves of early spring plants, whereas both cyclopropane and cyclopropene fatty acids were found in root, leaf, stem, and callus tissue in plants of the Malvaceae [9].
The presence of CPFA has also been documented in some aquatic invertebrates, marine isolates [24, 25] and in the lipid composition of mushrooms, mainly belonging to the family
CPFA synthesis involves the transfer of a methylene group from S-adenosyl methionine by the CPFA synthase to the cis double bond of the precursor unsaturated fatty acids, already integrated into phospholipids of cellular membrane [5]. A proposed pathway for the biosynthesis of dihydrosterculic acid from oleic acid is shown in Figure 2.
Biosynthesis of dihydrosterculic acid from oleic acid by CPFA synthase.
The reaction is a post synthetic modification and has been widely studied in microorganisms such as
Cyclopropane fatty acids are not essential fatty acids, but the bacterial production of cyclopropane ring seems to be related to changes in the membrane fatty acid composition of that microorganisms. In fact, the presence of these specific fatty acids seems to favor the stress tolerance of several bacteria strains to adverse environments (including ethanol, osmotic and oxidative stress, hot temperature, and low pH) and likely plays a role in the pathogenesis of bacterial infections [32].
The acid tolerance of individual strains of
Natural CPFA occur widespread with a cis configuration about cyclopropane moiety [5]; however, trans cyclopropane fatty acids are common in the cell envelope of
Cyclopropane fatty acids tend to promote the fluidity of lipid bilayers by interfering with lipid packing, improving the formation of gauche defects originating partly from the steric restraints caused by the methylene moieties and increasing lipid diffusion [31]. This could explain how cyclopropane fatty acids can improve the stability of the membrane against adverse conditions and, at the same time, reduce its permeability against toxic compounds.
CPFA are cellular components of lactic acid bacteria (LAB), such as
Recently, we reported the presence of CPFA in ensiled feeds (as maize silage) and in milk and cheeses from cow fed with silages [10, 11]. Some LAB strains, both homofermentative such as
Omega-cyclohexyl fatty acids (CHFAs), as 11-cyclohexyl undecanoic and 13-tridecanoic acids (Figure 3), occur in several acido-thermophilic bacteria, mainly in
Chemical structure of 11-cyclohexylundecanoic and 13-cyclohexytridecanoic acids.
Cyclohexanecarboxylic acid starter unit in omega-cyclohexyl fatty acid synthesis is derived from shikimic acid, and it is probably related to glucose metabolism [37].
In the following paragraph, information about the distribution of omega-cyclohexyl fatty acids, their biosynthesis, and their role on the cellular membrane will be provided.
Omega-cyclohexyl fatty acids are the principal lipid component of saponifiable fraction of
The occurrence of a fully saturated and monosubstituted cyclohexane ring is rare but derivatives of cyclohexyl acid, precursor of omega-cyclohexyl fatty acid biosynthesis, have been isolated from the extract soil and shoots of
In eukaryotes, the identification of 11-cyclohexylundecanoic fatty acid has been documented as a minor component of butter fat [40], then in sheep fat (0.05% of the total weight of fatty acids) [39] and more recently in cow milk [11]. In this previous work [11], they focused on the identification and characterization of cyclic fatty acids in cow milk to study the effect of diverse types of dairy diet on milk fat composition. 13-cyclohexyl tridecanoic acid methyl ester was well detectable in all milk samples by GC-MS analysis of fatty acid methyl esters (FAME), and its presence was confirmed by mass spectra and the synthetized standard.
The presence of omega-cyclic fatty acids in milk could be related to acidic ruminal fermentation patterns. An increase in starch as well as a decrease of less digestible fiber content favors the growth of amylolytic bacteria. This leads to an increased concentration of rumen volatile fatty acids such as butyric and propionic acids, a decrease of rumen odd and branched fatty acids [41] and lactate accumulation, resulting in a pH drop, which favors not only the development of the subacute ruminal acidosis (SARA) [42] but also the growth of thermo-acidophilus bacteria, which produce omega-cyclohexyl fatty acids. In this context, the presence of omega-cyclohexyl fatty acids in milk, especially 11-cyclohexylundecanoic and 13-cyclohexyltridecanoic acids, could be represented as a parameter to detect SARA, as proposed by other authors for odd- and branched-chain fatty acids [41]. However, this hypothesis has never been confirmed by experimental data.
Cyclic fatty acids are generally secondary compounds in fatty acid profiles of food; however, due to the recent discovery, some gaps of knowledge must be fulfilled. In some cases, especially cyclopropane fatty acids, they could reach the g/kg of total fat content in meat and dairy products [12, 43] and their dietary intake may be not negligible.
Therefore, it would be interesting to investigate on their metabolism in humans and eventual physiological effects, considering that bacteria produce cyclic fatty acids to enforce their membranes. The aim of these studies is to achieve a first never reported picture of the occurrence of CPFA in humans and their possible health effects.
In the following paragraphs, we focused on the investigation of CPFA content in foods to estimate their dietary intake and on their potential bioaccessibility in humans. Finally, a review of literature data about their potential biological effects on mammals will be provided.
Data reported on CPFA, mainly in dairy products, meat, and fish, were obtained in previous publications [10, 11, 12]. The content of cyclopropane fatty acids has also been evaluated in other food categories such as probiotic food supplements, vegetable edible oils (e.g., extra virgin olive, corn, soy, and peanuts oils) and cocoa butter, soy-derived products, and mushrooms (data not published). CPFA content in food categories, resulted positive in previous analysis, is shown in Table 1.
Food | No. of positive samples to CPFA2/tot | Mean ± SD (mg/kg total fat) | Range (mg/kg total fat) |
---|---|---|---|
Cow milk | 49/50 | 310 ± 240 | 70–830 |
Grana Padano (Lombardy, Italy) | 72/72 | 540 ± 110 | 300–1000 |
Other cow cheeses | 30/79 | 360 ± 180 | 180–1000 |
Commercial butter | 6/10 | 200 ± 100 | 90–335 |
Yoghurt/fermented cow milk | 4/4 | 200 ± 20 | 170–240 |
Commercial beef meat | 5/5 | 200 ± 100 | 200–400 |
Eel | 2/2 | 500 ± 250 | 400–590 |
Mullet | 1/1 | 700 ± 100 | 600–800 |
Results showed that among all the analyzed food categories, the most important CPFA food source is Grana Padano cheese, reaching concentration levels of 1 g/kg total fat (Table 1). CPFA were detected not only in commercial bovine meat (200–400 mg/kg total fat) but also in some species of fish (eels and mullets) with concentrations between 400 and 800 mg/kg total fat [12], probiotics, and in mushrooms (data not published). On the contrary, poultry, pork meat, vegetable oils commonly consumed (e.g., extra virgin olive, corn, soy, and peanuts oils), and cocoa butter were all negative to CPFA (data not shown), indicating that CPFA presence in foodstuffs of animal origin is correlated with the use of silages in the animal feedings, whereas plant organisms generally do not produce CPFA. As a whole, our results demonstrate the bacterial and fungal origin of CPFA in foods [16, 44]. Finally, the estimated daily, weekly and monthly CPFA dietary intake in the total Italian population (all sex and ages) [45] resulted in the milligrams order, so not negligible in view of a possible physiological action by CPFA on humans. Furthermore, food processing, manufacturing, seasoning steps, and fermentation [10] seemed not to affect CPFA content in the analyzed food matrices. Certainly, CPFA can be considered unknown components of the human diet, and additional information about their possible impact on humans is useful to provide a further understanding on the link between diet and human health.
Triglycerides (TG) are the major components of dietary fats, and once ingested, they are submitted to a hydrolytic process catalyzed by lipases present in gastric and especially in duodenal digestive juices [46]. Nowadays, the evolution of the triglycerides during digestion is a subject of great interest in lipid research, as much as the development of methodologies able to evaluate both qualitatively and quantitatively all the products generated from this process [13].
As reported in the previous paragraphs, no information is present in literature about the fate of CPFA within the human body, and a thorough investigation of how CPFA accumulate and are metabolized in humans is needed. In [13], the rate of CPFA digestibility has been assessed through their lipolysis and resistance to
Lipid classes | CPFA before digestion | CPFA after digestion |
---|---|---|
TG | 540 ± 20 mg/kg | ≤LOD (60 mg/kg) |
FFA and MG | ≤LOD (60 mg/kg) | 520 ± 10 mg/kg |
Free (as FFA and MG) and bound (as TG) CPFA in Grana Padano cheese before and after in vitro simulated human GI digestion.
Results are expressed in mg/kg of total extracted fat as mean ± standard deviation. FFA, free fatty acids; MG, monoglycerides; TG, triglycerides. Cyclopropane fatty acids (CPFA) refer to the sum of dihydrosterculic and lactobacillic acids [13].
These observations are encouraging, since CPFA seemed to be potentially efficiently absorbable and, ideally, bioavailable. Certainly, additional research is needed to evaluate the diffusion of these unusual fatty acids through the membrane of the small intestine epithelial cells as well as their presence in human plasma. For this purpose, an
Cyclopropane and omega-cyclohexyl fatty acids play a significant role in increasing the chemical and physical stability of bacterial membranes to adverse conditions [8]. To the best of our knowledge, little information is reported in literature about the effect of cyclic fatty acids in higher animals. However, some papers concern about biological activity of cyclopropene fatty acids, mainly sterculic acid, in mammals [9, 47, 48, 49]. On the contrary, omega-cyclic fatty acids remain an under investigated lipid class from a nutritional and physiological significance.
Many seed lipids containing cyclopropene fatty acids are extensively consumed by humans, especially in tropical areas [9]. It has been documented that their dietary leads to the accumulation of hard fats and other physiological disorders in animals [9].
Some studies suggested the effect of sterculic acid on lipid metabolism in mammals, especially in dairy sheep [47] and in human Caco2 cells [48], as inhibitor of Δ9-desaturase, which has a key role in the endogenous synthesis of cis-9, trans-11 conjugated linoleic acid (rumenic acid), known to have interesting properties in improving human health.
It is also known that sterculic acid is a potent inhibitor of stearoyl-CoA desaturase (SCD) involved in the biosynthesis of monounsaturated fatty acids (MUFA). SCD catalyzes the NADH- and O2-dependent desaturation of palmitate (16:0) and stearate (18:0) at carbon 9 to produce palmitoleate (cis-9, 16:1) and oleate (cis-9, 18:1), respectively, and has a crucial role in regulation of adipocyte proliferation/differentiation of adipocytes, mainly in ruminant species [49, 50]. Due to the structural analogies between cyclopropene and cyclopropane fatty acids, it is possible to hypothesize a possible physiological role for CPFA in lipid metabolism as well.
Fatty acids (FA) with a cyclopropane in the structure, especially cyclopropaneoctanoic acid 2-hexyl (CPA2H), have also been recently identified in human serum and adipose tissue of obese patients [32, 51] suggesting that they are absorbed as the other fatty acids and can be selected markers of metabolic disorders such as dyslipidemia, inflammation, and increased cardiovascular risk. These studies reported that both obese patients with hypertriglyceridemia and non-obese patients with chronic kidney disease (CKD) presented elevated serum levels of CPA2H, suggesting a positive correlation between high serum levels of CPA2H and high serum TG and cholesterol concentrations rather than to body mass or body mass index (BMI). These results show that CPA2H negatively affect the cellular lipid metabolism; however, the relevance of altered serum concentrations of this fatty acid remains still unclear.
Previously, it has been reported that cyclopropane fatty acids can influence the pathogenicity of
TNF is an inflammatory cytokine produced by activated macrophages and plays a key role as a mediator of intestinal inflammation [52]. In [52], they studied select strains of human-derived
Since significative amount of dihydrosterculic acid had been found in foods, mainly in dairy products, this fatty acid can be considered a new as well as unknown component of human diet. However, no specific works both
Future studies should elucidate how and whether this uncommon FA may have a biological role and clarify its healthy or unhealthy effects in humans.
In the last decades, food frauds have been on the rise [53]. For this reason, food authentication represents an important strategic issue for food industry because consumers are becoming increasingly interested in the quality and origin of foods. This is especially true when consumers purchase expensive certified and high added-value products, such as protected denomination of origin (PDO) or protected geographical indication (PGI) products [54].
Assuring food authenticity is not only an economical issue for food industries but it also concerns consumer safety, due to the substitution of food grade materials by cheaper non-food grade materials or to the presence of undeclared ingredients. The broad objective in food authentication is to identify unique or groups of markers to characterize the authenticity of food or their potential adulterants/contaminants and use them to resolve authenticity problem [55, 56].
As previously reported, cyclopropane and ω-cyclohexyl fatty acids, isolated respectively in lactic and rumen bacteria, have been identified in milk and dairy products as well as in meat. The occurrence and the content of cyclopropyl fatty acids in dairy products and meat were mainly correlated with the presence in forage of maize silage, whereas omega-cyclohexyl fatty acids have been proposed as marker of species, especially for ruminant species. In the following paragraphs, we will focus on the role of cyclic fatty acids as quality markers in food authentication mainly in dairy products and meat.
In dairy sector, the most critical issue in authentication is related to PDO cheeses, which are high commercial value products confined according to legislative and proper labeling rules. The higher prices of PDO products encourage more frequent food fraud [57]. Their authenticity is associated with several factors, such as the geographical area of production, materials, and technology used. In fact, cheese production can differ according to the feeding system of the animals providing all the ingredients as milk, the starters used, and the presence or lack of preservatives as well as other parameters (i.e., the heating temperature, the salting, the ripening time). All of these generate defined characteristics, which in turn can be detected by several analytical techniques, and provide a trace of the cheese origin [58, 59].
Among PDO cheeses, Parmigiano-Reggiano is probably the most worldwide appreciated Italian PDO cheese. It represents a fully natural high-quality cheese only made in a very small and specific region of Italy, without the use of additives and from milk of local cows fed with hay and not silage as fodder commonly used worldwide in livestock feeding. It is made according to the Production Specification Rules laid down by Parmigiano-Reggiano Cheese Consortium (CFPR) according to EU regulations (EU 510/2006 and following 1151/12). Due to the high quality of the raw material, the long ripening, and the strict rules of production, it is an expensive cheese, but despite this, a constant growing of the national and international market is registered [60]. Consequently, the problem of fraud is a critical issue. In fact, several grated varieties branded as Parmesan and with “Italian sound” elements on the pack were found to be inauthentic, some of them containing non-declared additives. Therefore, mislabeling is a severe problem concerning unfair competition and deception to the detriment of consumers.
As previously reported, data collected by the authors [10, 11, 43] on hundreds of milk and dairy samples confirm the strict correlation between the use of silages in the feeding and the presence of CPFA in milk fat. Cyclopropane fatty acids (CPFA) were present only in dairy products from cows fed with silages, and their determination has been demonstrated to be molecular markers of quality for PDO cheeses, as Parmigiano-Reggiano, where the use of silage is forbidden [10]. In this context, an example of successful case was the innovative method (UNI11650) that has been developed for Parmigiano-Reggiano cheese authentication based on the presence or absence of CPFA [43]. As results, Grana Padano (GP) samples were always positive to CPFA, reflecting that silages are not forbidden for their production (Figure 4). The amount of CPFA found in Grana Padano is variable, and it ranges from 300 to 830 mg/kg of fat, with a global mean value of 540 ± 110 mg/kg [43].
Enlarged view of CPFA peak elution zone and comparison between a sample of Grana Padano cheese positive to CPFA and a sample of Parmigiano-Reggiano cheese negative to CPFA [
Because grated parmesan is particularly vulnerable to being adulterated with other cheeses, mix of Parmigiano-Reggiano with a cheese produced with milk from ensiled-fed cows have been analyzed to establish the minimum level of adulteration. The GC-MS method [43] was able to detect frauds that included 10–20% of cheaper cheeses. Adulteration behind this value has scarce commercial significance. Furthermore, the optimized GC-MS method was subjected to validation in terms of precision, accuracy, linearity, detection, and quantitation limits following the recommendations of the International Conference on Harmonization [61]. Therefore, due to the innovative and encouraging results, an application for an official standardization of the method (UNI method 11650) has been validated and included in Parmigiano-Reggiano Product Specification Rules among the official controls, enforcing the current analytical methods adopted for the quality controls.
In conclusion, the presence of CPFA in milk and dairy products probably derives from their presence in ensiled feeds, where CPFA can be released by bacteria during fermentation. The environmental conditions developed in silos seem to be essential for the production and release of CPFA from bacteria, whereas shelf-life, manufacturing, seasoning steps, and lactic fermentation did not affect CPFA content [11]. As a whole, CPFA demonstrated to be interesting molecular markers, able to distinguish cheeses obtained from cows fed with or without silages. Moreover, the quantitative GC-MS method developed is relatively simple, assures a quick sample preparation, and relies on available instrumentation, thus making it suitable for the screening of many samples with a good cost-per-analysis ratio.
An increasing critical issue is the substitution of higher commercial valued meats by low-priced ones and the fraudulent labeling of meat species [62]. In this context, there is the need for new, fast, and reliable analytical methodologies and easily quantifiable markers to be used for meat authentication and to protect both consumers and producers from illegal substitutions. Current methods to identify the origin of species present in commercial meat are based on DNA and ELISA, but also UPLC, Raman spectroscopy, low-field NMR, and mass spectrometry have been considered [63].
Fatty acids in food authentication were mainly used for the determination of the cow feeding system, which affect the milk and meat fat composition [64, 65]. Previously, many data have been collected confirming the association between the use of ensiled feeds and the presence of CPFA in the fatty profile of dairy products.
As suggested by Lolli et al. [12], cyclopropane fatty acids (mainly dihydrosterculic acid) have also been detected in animal fat, especially in bovine meat fat. As results, CPFA were detected in the fatty profiles of commercial bovine meat samples but they were absent in the samples of certified meat from cows not fed with fermented forages, reflecting the same correlation observed in dairy products [10, 11, 43]. In the case of meat of other animal species (pork, pork cured meat, and chicken), results did not show the presence of cyclopropane fatty acids as shown in Table 3. These preliminary results suggested that CPFA might be proposed as markers of silage feedings and for the authentication of high quality costly meat whose producers declare the absence of silages in the feeding as in dairy products. Certainly, it will require the construction of a robust database of certificated meat for the feeding system. Moreover, CPFA (mainly lactobacillic acid) were recently found [12] in farmed fish. Therefore, this approach could also be extended to fish to eventually distinguish farmed from wild fish.
Regarding omega-cyclohexyl fatty acids, they have been detected [11] (mainly 11-cyclohexyl undecanoic and 13-cyclohexyl tridecanoic fatty acids) in the GC-MS fatty profile of cow milk, suggesting their presence in milk fat could represent a reliable method to evidence rumen acidosis in cows. However, as mentioned above, this hypothesis has never been confirmed by experimental data.
Recently, they have been also identified in animal fat, mainly in meat of ruminants, especially bovine and ovine meat [14]. Preliminary data (not published) showed that omega-cyclohexyl fatty acids, combined with other fatty acids as branched chain fatty acids [41], permitted to discriminate beef from pork meat. As suggested by Marseglia et al. [11], 11-cyclohexyl undecanoic fatty acid methyl ester from milk and meat fat eluted in the chromatographic region of isomers of the oleic acid, so it was detected by the characteristic molecular ion 282 m/z in the mass spectrum.
13-cyclohexyl tridecanoic fatty acid methyl ester was detectable in the GC-MS profile as it elutes just before the eicosanoic acid (arachidic acid) and after eicosenoic acid. However, due to the presence of interfering signals, the identification of 13-cyclohexyl tridecanoic was confirmed by the mass spectrum with the characteristic molecular ion 310 m/z and the previous biosynthesized compound [11]. The characteristic mass spectra of 13-cyclohexyl tridecanoic fatty acid detected by GC-MS analysis is shown in Figure 5.
Mass spectra of 13-cyclohexyl tridecanoic fatty acid methyl ester [
The results from the GC-MS analysis showed that omega-cyclohexyl fatty acids, both 11-cyclohexylundecanoic acid and 13-cyclohexyltridecanoic acid, were present only in bovine and ovine meat samples with values between 90–230 and 20–200 mg/kg of the total meat fat, respectively [14]. On the contrary, they were absent in pork, horse, chicken, and rabbit, reflecting the ruminal origin and a possible application for the detection of bovine/pork ratio in commercial minced meat [14].
As mentioned above, current analytical methods in meat authentication are mainly based on protein or DNA measurement, which are not directly comparable to labeled meat expressed as percentage (w/w) [66]. Furthermore, analytical procedures based on protein analysis are sensitive to heat treatment. Therefore, they could not be applied to cooked products for the quantitative analysis. In this context, a quantitative GC-MS method is going to be developed on mixtures of beef and pork meat, both raw and cooked (ragout), based on the method previously applied to determine CPFA [43] and combining other fatty acids, as iso-branched chain fatty acids, of ruminal origins [41].
Preliminary results [14] showed that omega-cyclohexyl and iso-branched chain fatty acids content decreased in minced meat, both raw and cooked, as function of bovine meat percentage in the sample, as shown in Table 4.
Percentage of bovine/pork in fresh meat | 11-cyclohexylundecanoic acid (mg/kg) | 13-cyclohexyltridecanoic acid (mg/kg) | Iso methyl C16:0 (mg/kg) | Iso methyl C17:0 (mg/kg) |
---|---|---|---|---|
100 bovine | 175 ± 7 | 55 ± 7 | 1500 ± 240 | 2240 ± 721 |
80 bov/20 pork | 120 ± 28 | 35 ± 7 | 1005 ± 49 | 1595 ± 219 |
60 bov/40 pork | 40 ± 1 | 20 ± 14 | 650 ± 14 | 1055 ± 148 |
40 bov/60 pork | 20 ± 1 | 15 ± 7 | 690 ± 42 | 860 ± 283 |
20 bov/40 pork | 15 ± 7 | 5 ± 7 | 200 ± 100 | 385 ± 21 |
100 pork | nd | nd | 90 ± 1 | 145 ± 21 |
Percentage of bovine/pork in ragout | 11-cyclohexylundecanoic acid (mg/kg) | 13-cyclohexyltridecanoic acid (mg/kg) | Iso methyl C16:0 (mg/kg) | Iso methyl C17:0 (mg/kg) |
---|---|---|---|---|
100 bovine | 100.0 ± 10.5 | 32.5 ± 1.9 | 821.7 ± 79.0 | 1166.0 ± 17.0 |
80 bov/20 pork | 80.0 ± 5.7 | 26.5 ± 0.1 | 690.8 ± 61.9 | 943.4 ± 125.4 |
60 bov/40 pork | 40.0 ± 1.7 | 11.1 ± 1.9 | 381.8 ± 33.3 | 539.7 ± 39.1 |
40 bov/60 pork | 6.8 ± 5.7 | nd | 238.9 ± 2.0 | 296.6 ± 20.2 |
20 bov/40 pork | 5.5 ± 1.3 | nd | 202.8 ± 35.2 | 233.0 ± 32.0 |
100 pork | nd | nd | 29.3 ± 1.9 | 56.2 ± 18.9 |
Concentration (mg/kg total fat) of omega-cyclohexyl and iso-branched chain fatty acids found in minced meat, both raw and cooked (ragout), as function of bovine meat percentage [14].
Results are expressed as mean ± SD of two replicates; nd = not detectable.
Therefore, the analysis of omega-cyclohexyl fatty acids combined with that of specific iso-branched chain fatty acids was able to detect until 20% of pork meat in beef, representing potential markers for ruminant meat, also detectable in complex matrix and after thermal treatment in ragout samples.
In conclusion, omega-cyclohexyl fatty acids can be proposed as markers of ruminant meat, especially of beef meat, which could enforce current analytical methods applied for labeling regulations.
Cyclopropane and omega-cyclohexyl fatty acids are carboalicyclic fatty acids widely distributed among microorganisms, enhancing the chemical and physical stability of bacterial membranes. Significant variations in the membrane content of cyclic fatty acids have been identified in a multitude of physiological situations. Recently, they have been detected in food of animal origins, so representing new components in human diet. In some cases, these cyclic fatty acids can act as markers of quality and their detection could enforce current analytical methods adopted in food authentication.
However, little is known regarding the actual role that these fatty acids play, their release, and the chemical basis of their effects on the cellular membrane, especially in higher animals.
We declare that we have no conflict of interest.
Under the global background of shortage crisis of forestry and fossil oil resources, it is estimated that there is an expectation for the application of natural fiber-reinforced composites from 12% in 2010 to 18% and 25% by 2020 and 2030, respectively [1]. With the fast-growing demands of engineering wood products for various applications, wood plastic composites (commonly abbreviated as WPC), as the most important one of natural fiber-reinforced composites, mainly produced by the thermoplastic polymers (polyethylene (PE), polypropylene (PP), polyvinyl chloride (PVC) and polystyrene (PS)) and the biomass particles and fibers from forestry and agricultural wastes (wood, bamboo, straw, stalk, husk and bast), which have been well considered as a crucial and novel candidate for residential and industrial constructions [2, 3]. WPC with a unique combination of advantages from wood and plastic has been extensively employed in landscaping facility, transportation, packaging, municipal engineering as well as the inner-outer decoration and structure of building [4, 5, 6], as seen in Figures 1–3. In recent years, WPC begins to partially replace some conventional and novel engineered wood products like wood veneer (WV), particle board (PB), medium-density fiber board (MDF), plywood (PW), oriented strand board (OSB) and laminated veneer lumber (LVL) [7].
The applications of WPC in various building construction.
The applications of WPC in the indoor or outdoor ceilings and sidings.
The applications of WPC in the furniture, kitchen, and bathroom products.
In the initial developing period of WPC, manufacturers claim that there are many advantages for WPC including high strength and modulus, excellent dimensional stability, outstanding biological (fungi and termite) resistance and low maintenance requirement [8, 9, 10]. Hydrophilic biomass particles or fibers can be effectively encapsulated by hydrophobic thermoplastic resin to provide well protection against biological invasion. Although it had to be admitted that there was a superior weathering and biological durability for WPC than solid wood, natural aging and biological degradation of WPC by common microorganisms (mold, algae and decaying fungi) and harmful termites indeed can be observed with the damage of its external layer and interfacial bonding under the appropriate circumstance like mild ambient temperature, high humidity and oxygen content as well as strong ultraviolet (UV) radiation [11]. Meanwhile, the insufficient mechanical properties and poor flame retardance due to weak interfacial compatibility, high fire sensitivity of polyolefin resins and the strength limitation of conventional resins were gradually exposed as the service time of WPC extended, which may lead to potential failures and serious accidents in engineering construction.
Recently, a growing interest for WPC used in the field of construction becomes more popular with pervasive consciousness of environmental protection and sustainability. To further improve the mechanical properties, durability and flame retardance, selection of wood species with various extractives, alloy modification with linear and aromatic polyamides as well as the addition of flame retardants with single and synergistic effectiveness have been reported. This provides a significant technological support for WPC’s future use in the construction.
The ever-expanding commercial market for WPC products in exterior construction engineering applications has placed more spotlights on improving the biological durability and lifetime of WPCs. The wood component of WPCs is considered as common fiber fillers with similar properties, including renewability, low density, high specific strength, and hydrophilicity. In fact, the species of wood plays a critical role in the comprehensive properties of WPCs, in addition to other factors, such as the plastic type, particle size, additives, and processing technology. Termites and other microorganisms, such as mold and fungi, can decrease the esthetic quality and mechanical strength of WPCs through discoloration and degradation by chemically altering the structures of lignin, hemicellulose, and cellulose fibers in the wood [12, 13]. However, algae colonization only affects the outer appearance of the WPC instead of the inner interfacial bonding [14]. To promote the quality and prolong the service time of the entire WPC structure, more attention needs to be paid to improving the biological durability during the engineering of the composites in the future. The chemical composition of wood extractives, such as tannins, fatty acids, aldehydes, ketones, sugars, and starches, have been reported to have both a negative and positive effect on the susceptibility of WPC to microbial invasion [11, 15, 16].
Despite of continuing emergence of new publications in this field, there are few reports on how the identity of the wood species affects the biological durability of WPCs. Different wood species contain varying compositions of volatile chemical components. The high toxicities of some natural wood extractives have been shown to exhibit a positive effect on the resistance of WPCs to microorganisms. The susceptibility of mold in PVC-based WPCs containing maple wood was found to be higher than the analogous WPCs made with pine wood [17].
The decay resistance to
The algae resistance of PVC-based WPC filled with different wood species: (a)
The mound resistance of PVC-based WPC filled with different wood species: (a)
The termite resistance of PVC-based WPC filled with different wood species: (a)
Several functional chemical extractives naturally present in wood varieties can either facilitate or inhibit the biodeterioration of WPCs. For example, 8-propoxycedrane, cedrol, α-cedrene, and β-cedrene in
Similar results for the PP-based WPCs filled with poplar, MOSO bamboo, ramin, pine, gum, cedar, and rubberwood were reported, as observed in Figure 8. There was a poor mold resistance of the WPC made with MOSO bamboo due to the presence of 5-hydroxymethylfurfural in the bamboo species. The WPC made with ramin wood showed high resistance to various mold species, which could be attributed to the presence of γ-sitosterol, cis-9, cis-12-octadecadienoic acid, benzyl alcohol, and 8-propoxycedrane. However, 4-hydroxy-3-methoxycinnamaldehyde and dehydroabietic acid were determined to be the crucial chemical components that mediated the high resistance of WPCs made by pine. The resistance of WPCs made with gum fillers to molds can be explained by the synergistic effect of γ-sitosterol, stigmast-4-en-3-one, and cedrol. The relatively low fungal resistance of WPCs filled with rubberwood was attributed to the relatively high content of 5-hydroxymethylfurfural. In addition, hinokitiol, cedrol, α-cedrene, thymoquinone, totarol, β-cedrene, ferruginol, hinokiol, and benzyl alcohol were found to be vital chemical compounds in WPCs filled with red cedar for manifesting a high resistance of the composite to molds. The relatively high contents of cedrol, stigmast-4-en-3-one, and 8-propoxy-cedrane in Chinese fir provided the corresponding WPC with significant resistance to mold growth. Meanwhile, the relatively low contents of α-Cedrene, β-cedrene, α-cadinol, and γ-sitosterol were beneficial for mitigating the biodegradation of WPC [21].
Mold colonization of PP-based WPC with various wood species: (a) poplar, (b) MOSO-bamboo (c) Chinese fir (d) Ramin, (e) pine, (f) gum, (g) cedar, (h) rubberwood [
The exposure of WPCs to ultraviolet light and moisture represents two significant natural weathering sources of WPCs in outdoor applications, which affects not only the visual appearance of the WPCs but also their mechanical properties by manifesting deleterious effects such as discoloration, furrows, and separated voids [22]. The photographs of unweathered and weathered WPCs are shown in Figure 9.
Photos of HDPE-based WPCs before and after natural weathering [
Chromophores naturally present in polymers and biomass generally accelerate the absorption of UV light, leading to the photodegradation of WPCs. Specifically, the photo-yellowing discoloration of weathered biomass can be attributed to the breakdown of lignin into smaller chromophoric monomers, including quinones, carboxylic acids, and hydroperoxyl radicals [23]. Polymer photochemical degradation is mediated by chain scission reactions, typically through Norrish Type I and II reactions (Figure 10). Norrish Type I reactions lead to the formation of free radicals by the cleavage of the ketones and aldehydes. On the other hand, carbonyl and vinylic groups are generated by Norrish Type II ring-opening reactions. Consequently, these photochemical degradation reactions lead to a reduction in the degree of chain entanglements in the amorphous zone, which results in the crystallization of smaller polymeric units and individual monomers, reducing the mechanical properties of the WPCs [24]. Some chemical additives, such as photostabilizers, antioxidants, and pigments have been incorporated into WPC matrices to retard the discoloration of the composites.
The reaction mechanism for photochemical degradation of polymer in WPC [
Moisture in the air, especially during the rainy season, can be easily absorbed by the hydrophilic biomass particles in WPCs, during which the biomass particles begin to swell and create micro-voids or cracks in the polymer matrix, resulting in decreases in both the interfacial adhesion between biomass particles and plastics and the stress transfer efficiency from the matrix to the fibers (Figure 11). Therefore, the elastic modulus and flexural strength of the WPCs gradually decrease. In addition, the individual components of biomass (i.e., cellulose, hemicellulose, lignin, and extractives) have varying susceptibilities to photodegradation. In fact, UV light, warm temperatures, and aerial moisture typically have a synergistic effect on the natural weathering of WPCs. When the biomass particles in WPC undergo photodegradation, the surface chemical groups trend to become more hydrophilic due to the formation of water-soluble products from the breakdown of lignin. The surface wettability increases and appears more sensitive to moisture levels. It was also found that the anti-weathering discoloration of WPC was reinforced after the biomass was extracted or delignified [25]. The surface roughness of PP-based WPCs before and after weathering was measured by atomic force microscopy [26], which indicated that there was an increase in the roughness value after the photodegradation of PP, leading to the presence of some microcracks in the WPC and the loss of biomass particles, and a decrease in the interfacial bonding on the weathered surface.
Scanning electron micrographs of various WPCs before and after weathering: a, c. HDPE-based and PP-based WPC that was unweathered, respectively; b, d: HDPE-based and PP-based WPC that 2-yr exterior-weathered, respectively [
Many studies have evaluated the natural anti-weathering properties of WPCs in various applications. WPCs containing 40 wt.% of the polymer demonstrated better resistance to natural weathering a polymer loading of 50 wt.% [27]. High humidity also was determined by various researchers to be a principal determinant of the loss of flexural strength. In WPCs prepared with rubberwood fibers and several polymeric matrices, including HDPE, LDPE, PVC, PP, and PS, PP- and PS-based WPCs had the smallest reductions in tensile and flexural strengths of the WPCs by natural weathering when the mass fraction of polymer was 60 wt.%. These results demonstrated that PP and PS were the two ideal choices for WPC engineering applications in which WPCs are required to resist high stresses and natural weathering [28].
The unfavorable mechanical properties of WPCs made with conventional PE, PP and PVC resins led to the placement of restrictions and safety risks on engineering construction products. Polyamides 6, 66, 1010, and 11 are typical engineering polymers that exhibit high strength and stiffness, excellent chemical stability, and outstanding heat resistance, and have the potential to promote the comprehensive properties of WPCs. PA6/biomass fibers composites have been directly fabricated by hot compression, extrusion, and injection at temperatures range from 230 to 250°C. However, severe thermal decomposition and poor dispersion of biomass fillers typically occurred during these manufacturing processes [29, 30, 31].
The melting and processing temperature of polyamide polymers can be decreased by the incorporation of lithium chloride (LiCl). LiCl and either maleic anhydride-grafted polyethylene (MA-g-PE) or maleic anhydride-grafted polypropylene (MA-g-PP) exhibited a synergistic effect on the mechanical strengths of PE- or PP-based WPCs with the reinforcement of the polyamide resin. Lithium cations (Li+) can be easily embedded into the amorphous and crystalline phases of PA6 by the coordination of amide nitrogen or oxygen atoms, thereby breaking hydrogen bonds and disrupting three-dimensional arrangements. The formation of the copolymer PA6-g-PE by the condensation of amine functionalities in the PA6 polymer with the grafted anhydrides were found to improve the interfacial bonding ability between high-density polyethylene (HDPE) and PA6. Li+ ions could also be complexed by the oxygen atoms of the anhydrides, which, too, promoted interfacial adhesion. On the other hand, biomass particles with rich hydroxyl groups synergistically reinforced the hydrogen bonds between PA6 and the wood flour (WF), underwent esterification reactions with MA-g-PE and WF, and complexed Li+ ions [32]. The total reaction mechanism can be depicted as Figure 12. The addition of 2 wt%-2.5 wt% LiCl to the MA-g-PE polymer matrix led to a maximum flexural strength, flexural modulus, and impact strength of the PE-based WPC that exceeded 100 MPa, 6000 MPa, and 12 kJ/m2, respectively. Similarly, the maximum flexural strength, flexural modulus, and impact strength of the PP-based WPC with 1 wt% LiCl were 115 MPa, 6500 MPa, and 10 kJ/m2, respectively [33].
Reaction mechanism diagram of LiCl and MA-g-PE in PE-based WPC [
Increasing the molecular weight of PA6 is another effective way to improve its mechanical properties. The reaction of the chain extender 2,2′-(1,4-phenylene)bis(2-oxazoline) (PBO) with the terminal groups of PA6 was found to increase the molecular weight PA6 from 33000 to 72800 after the chain extender being incorporated into the melting polycondensation systems, the mechanism of which is shown in Figure 13. During the initial stage of chain elongation, the two oxazoline rings were opened, which then reacted with the two terminal carboxylic acid groups rather than the amine functionalities of the PA6 polymer, leading to the extension of the PA6 molecular chains. In addition, hydrogen bonding between the amide groups in PA6 and the hydroxyl groups in WF, as well as the noncovalent interactions between the oxygen and nitrogen atoms in PBO and the hydroxyl groups in WF, enhanced the interfacial bonding ability of PA6 and WF. PBO and LiCl were simultaneously used to modify the PA6-reinforced WPC, after which the melting point and processing temperature of PA6 decreased from 220–190°C and 240–210°C, respectively, which effectively mitigated the discoloration and thermal decomposition of the WPC. The modification of PA6 by PBO effectively improved the mechanical properties of the WPC by increasing the tensile strength, flexural strength, and modulus by 43%, 30%, and 37%, respectively [34].
Reaction mechanism diagram of the chain growth of PA6 [
Recently, the incorporation of novel, environmentally friendly polyamide copolymers matrices PA6/11 containing ε-caprolactam and 11-aminoundecanoic acid into WPC products was studied. The chain extension reactions of the PA6/11 copolymer were inhibited by the generating water from condensation reactions when the ε-caprolactam content was high. The melting temperature of the PA6/11 copolymers with the ratio of 40 to 60 can decreased to 120°C, which enabled the processing of the WPC below the thermal decomposition temperature of WF. In addition, when the ratio of PA6:PA11 was 70:30, the corresponding WPC exhibited outstanding ductility, with a strain at break of 15 to 20% [35].
The thermal modification of natural biomass fibers by superheated vapor has also proved to be a green, facile, and effective method for improving the mechanical and thermo-stable properties of WPCs. During this process, no chemical reactions ensue between the biomass fibers and exogenous reactants; instead, only chemical transformations within and between polymers, such as cellulose, hemicellulose and lignin, occur. Hemicelluloses are often hydrolyzed into oligomeric or monomeric structures at high temperatures. The hydroxyl groups of cellulose chains, as well as some chemical bonds that can be broken to form phenolic groups in lignin polymers, resulting in a reduction in the polarity of the biomass fibers and an improvement in their compatibility with non-polar HDPE resins [36]. The modification of rubber seed shell (RSS)-reinforced HDPE-based WPCs by superheated vapor at 200°C and 220°C is illustrated in Figure 14.
The HEPE-based WPC with RSS modified by various superheated vapor temperatures: a. control, b. 200°C, c. 220°C [
The superheated vapor treatment improved the mechanical strengths and thermal and dimensional stability of RSS, as well as its compatibility with HDPE. The fractured cross-section of the RSS/HDPE composites after RSS modification showed a rough morphology similar to a “thorn” due to strong interactions between the RSS and the HDPE matrix, such that the RSS fibers were pulled out during fracturing (Figure 15). The RSS particles modified at 200°C significantly enhanced the interfacial bonding ability of the RSS/HDPE composites and manifested outstanding mechanical properties. The flexural and tensile strengths of the RSS/HDPE composites were increased by 21.27% and 12.92% after modification of the RSS at 200°C and 220°C, respectively [37].
Micro-morphology of the HDPE/RSS composites with unmodified and modified RSS by superheated vapor:a. unmodified, b. modified [
Superheated vapor modification mitigates the severe thermal degradation of biomass fibers during the heating processing, while the interfacial bonding can be promoted at the ideal ratio. The fractured surfaces of the PA6/HDPE/WF composite with HDPE:PA6 ratios of 8:2 and 7:3 both exhibited a rough appearance with many voids and separated structures, corresponding to the poor compatibility among WF, PA6, and HDPE [38]. These results were consistent with the weak interfacial bonding of PA6/HDPE/clay composites with when the weight ratio of HDPE:PA6 was 80:20 [39]. However, the HDPE:PA6 compatibility was markedly improved when the HDPE:PA6 ratio was 6:4, as the composite exhibited a coarse cross-section consistent with “thorns” similarly with Figure 15. The effect could be attributed to WF pulling out during fracturing with a strong interfacial bonding as mentioned above. The PA6 and modified wood fibers synergistically reinforced the interfacial adhesion only at a 6:4 ratio of HDPE:PA6, which was determined to be the optimal ratio. The flexural strength and flexural modulus of the PA6/HDPE/WF composite increased by 82.05% and 64.08%, respectively, compared to the control HDPE-based WPC. In addition, the tensile and impact strengths increased by 93.47% and 120.45%, respectively, and the maximum thermal degradation temperatures corresponding to the first and second decomposition stages increased by 7.17°C and 8.99°C, respectively. Moreover, the water absorption ratio of the PA6/HDPE/WF composite was controlled within 1.50%. Overall, these results demonstrated that the HDPE/PA6-modified WF composites have great potential in construction and building engineering applications as WPC products (Figure 16).
The PA6/HDPE/modified WF composites: a. the samples with different ratios in the lab, b. the products in the factory.
Poly(p-phenylene terephthalamide), manufactured under the name Kevlar® by the Dupont corporation, is a linear polyamide featuring additional benzene rings in the polymer chain. Kevlar fibers (KFs) can be used as another novel reinforcement for WPC because they are resistant to combustion and have a high specific strength and modulus, superior toughness, and excellent chemical and thermal stability.
While KFs have been incorporated into WF/HDPE composites, their chemical inertness and low surface energy were found to be deleterious to the interfacial adhesion of the polymers within the composites. Prior to the addition of KFs, many voids and holes between the WF and the HDPE matrix on the fractured surface with the pullout of WF were attributed to poor interfacial adhesion (Figure 17a). The modification of KFs with allyl and 3-trimethoxysilylpropyl groups improved the compatibility between the WF and HDPE matrices, resulting in an increase in the mechanical properties of the composites (Figure 17b). The tensile strength and modulus of the KFs-reinforced WPC increased to 23.1% and 31.4%, respectively, while the notched and unnotched impact strengths of the reinforced WPC increased to 42.8% and 52.3%, respectively, when the KF loaded was below 3% compared to the unmodified WPC. In addition, the alkoxysilane groups on the KFs can be hydrolyzed to generate silanol groups or siloxane networks, which can engage in hydrogen bonding with the hydroxyl groups in WF. There was a physical anchor bonding among the melting of HDPE, KF, and WF. Meanwhile, free-radical reactions between HDPE chains and allyl groups may have occurred during the extrusion process. The flexible KFs with diverse S, J, C, and I configurations is shown in Figure 17c. The major structural failures included matrix, fiber, and interface fractures as well as fiber fibrillation and buckling. The various configurations of the KFs contributed to the mechanical interlocking among KF, WF, and HDPE components, which promoted an efficient stress transfer from the resin matrix to the KFs. Therefore, the reinforcement of WPCs with KFs can bestow the WFCs with the strength and toughness required for engineering applications [40]. However, until now, there has been very limited research conducted in the field of Kevlar and natural biomass fiber-reinforced composites. Nonetheless, the incorporation of KFs into WFCs can be considered a promising modification for the improvement of the mechanical properties of WPCs in various engineering applications in the future.
The Kevlar reinforced HDPE-based WPC: a. HDPE/WF, b. HDPE/WF/KF, c. the assumed configuration of KF [
The continued development of WPCs for a variety of different engineering applications, as well as the increased demand for more safety-consciousness products, has necessitated the development of flame-resistant materials as a substitute for some of the conventional engineering materials used in WPCs. Currently, PE- and PP-based WPCs are most often utilized in building exterior and outdoor products because PP and PE both have a high sensitivity to flame, which means they can quickly burn when ignited, leading to hazardous scenarios. Meanwhile, PVC-based WPCs are most often used in indoor products; although PVC has a relatively low flammability and inherent self-inhibited flame properties compared to PE and PP, PVC often does not comply with the safety requirements and regulations of governments because it releases a significant amount of toxic smoke while burning. Thus, it is necessary to improve the flame resistance of WPCs to expand their potential engineering applications. Many strategies that have been developed to enhance the flame resistance of WPCs can be divided into two general categories. The first is the incorporation of fire retardants into biomass particles and polymers during the compression, injection, and/or extrusion processes. The other strategy entails the pretreatment of the biomass particles with liquid flame retardants by impregnation, after which the particles can be combined with the polymers using the conventional processes.
The major flame retardants used in WPCs include halogenated and nonhalogenated chemicals. The halogenated flame retardants mainly include brominated and chlorinated molecules that function to reduce the heat release and inhibit combustion by quenching the burning of the materials. Nevertheless, they emit toxic or corrosive gases that harmful to the environment while burning. Hence, they have been gradually withdrawn from use because of added pressure from many governments around the world. In recent years, though, some novel halogen-free flame retardants like phosphorus-based flame retardants, boron-based flame retardants, metal hydroxide flame retardants and intumescent flame retardants have been developed.
Many different evaluation methods of flame retardancy are available for various materials, among which the limited oxygen index (LOI), UL-94 V, and cone calorimeter burning testing are most frequently used for WPC products.
The LOI, which is also referred to as the critical oxygen index (COI) or oxygen index (OI), was first introduced by Fenimore and Martin in 1966. It is defined as the minimum concentration of oxygen in an atmosphere composed of a mixture of oxygen (O2) and nitrogen (N2) at 25°C required for supporting the continuous flaming combustion of a material sample. LOI has been included in several international and national standards, such as ISO 4589 and ASTM D2863 [41]. Specifically, the testing involves placing a WPC sample with a candle-like shape vertically in a glass column while feeding the sample an atmosphere of O2 and N2. After the WPC sample is ignited from the top, the oxygen concentration is decreased (i.e. the nitrogen concentration is increased) until the minimum oxygen concentration that allows for the sustained burning of the sample is determined. Prior to observation and evaluation, the sample should be at a stable burning stage. The testing can be considered as an effective result if one of two situations occurs: either the sample continues burning 3 min after the removal of the fire source or the consumed length of the sample is within 5 cm [42]; otherwise, a new sample should be retested at an adjustable O2 concentration. The LOI test has been considered one of the most useful testing methods for determining the flame retardance of PE-based and PP-based WPCs since it can provide a precise rating on a numerical basis.
The UL-94 V method was initially designed to evaluate the flammability of plastic materials for parts in devices and appliances and is also accepted throughout the world as a standardized method. Similar to the LOI, it also is used to assess the flame retardancy of PE-, PP- or PS-based WPCs. In this method, a bar-shaped sample is placed vertically and held from the top. The sample is ignited twice by a Bunsen burner, and the total sustained combustion time is recorded after each burning. A second burning will be conducted if the sample is self-extinguished after the first burning. Based on the results, the WPCs can typically be classified into V-0, V-1, and V-2 levels. The V-0 level means that the specimen is extinguished less than 10 s after it is ignited. The V-1 level corresponds to a maximum combustion time of a sample of less than 50 s without any combustible drips, or the combustion time for five samples is less than 25 s [43]. Often, standard cotton is positioned under the sample to determine whether the combustible drips will ignite the cotton. The sample is classified as V-2 when the combustion times comply with the requirements of V-1 level, but some of the flammable drips ignite the cotton.
The LOI and UL-94 V methods generally are facile, fast, and reproducible. However, these methods typically only provide a single test parameter. The test results cannot be well-quantified and are difficult to correlate with the burning behavior of the material in a real fire scenario. In addition, the evaluation of identical materials using different experimental methods can generate conflicting results. Instead, cone calorimetry is the most effective way to measure and simulate the flammability behavior of a medium-sized WPC sample, as it provides abundant test parameters, including the time to ignition (TTI), heat release rate (HRR), mass loss rate (MLR), total heat release (THR), total smoke release (TSR), and effective heat of combustion (EHC) [42]. It also can be used to predict the large-scale testing results in fire-protection engineering, and it is incorporated into various international standards like ISO 5660 and ASTM E1354 because of its availability. The basic principle of cone calorimetry relies on the measurement of decreasing oxygen concentration in a mixture of gases during the combustion of a sample exposed to a constant heat flux.
Phosphorus-based flame retardants can be traced back to the nineteenth century when ammonium phosphate was used to prevent the burning of theater curtains in France. The surface of wood materials has been coated with a mixture of phosphoric acid and other curable resins to modify the flammability of various materials in early Canada. Nowadays, it has become an important flame retardant for improving the flame resistance of WPCs. Phosphoric acid can facilitate the formation of char in the condensed phase and reduce the presence of flammable radicals in the gas phase, which leads to an enhancement of the flame retardance of WPCs [44]. Several kinds of phosphorus-based flame retardants, including ammonium polyphosphate (APP), aluminum hypophosphite (AHP), monoammonium phosphate (MAP), melamine phosphate (MP), melamine polyphosphate (MPP), and red phosphorus (RP), have been introduced into the formulations of polyolefin-based WPCs. Table 1 lists the cone calorimetry testing results for WPCs containing several phosphorus-based flame retardants. It was concluded that there APP demonstrated a better flame resistance of WPC compared to DAP and MPP, while the effectiveness of DAP was lower than MPP.
WPC samples | Weight ratio | TTI (s) | pHHR (kW/m2) | THR (MJ/m2) | Reference |
---|---|---|---|---|---|
WF/PP | 60/40 | 21 | 359 | 87 | [45] |
WF/PP/APP | 60/40/20 | 22 | 208 | 68 | [45] |
WF/PP | 40/60 | 19 | 535 | 319 | [46] |
WF/PP/MPP | 36/56/8 | 20 | 470 | 300 | [47] |
WF/PP | 40/60 | 19 | 535 | 319 | [46] |
WF/PP/DAP | 36/56/8 | 19 | 495 | 299 | [46] |
WF/HDPE | 30/70 | 28 | 194 | 71 | [48] |
WF/HDPE/APP | 30/70/10 | 19 | 113 | 62 | [48] |
WF/HDPE | 40/60 | 35 | 422 | 102 | [49] |
WF/HDPE/MPP | 40/60/35 | 36 | 202 | 45 | [49] |
WF/HDPE | 40/60 | 23 | 523 | 335 | [46] |
WF/HDPE/DAP | 37/57/4 | 22 | 466 | 311 | [46] |
Results of cone calorimeter for polyolefin-based WPC with various phosphorus-based flame retardants.
Boron-based flame retardants, which often contain additional functionalities, such as smoke suppressants, afterglow suppressants, and antitracking agents, are early used for cellulose-containing products [50]. However, the use of zinc borates (ZB) and a mixture of boric acid (BA) and borax (BX) as flame retardant in WPCs has gained more attention. Table 2 lists the cone calorimetry testing results for WPCs with two typical boron-based flame retardants. PP-based and PE-based WPCs demonstrated improved fire retardance due to increased TTI and decreased pHRR and THR values after incorporating ZB and BA-BX. The polyolefin WPC containing ZB demonstrated a superior effectiveness over BA-BX, but ZB has been determined to not be an ideal flame retardant for PVC-based WPCs because PVC has an intrinsic flame resistance given the presence of chlorine atoms in the polymer [54].
WPC samples | Weight ratio | TTI (s) | pHHR (kW/m2) | THR (MJ/m2) | Reference |
---|---|---|---|---|---|
WF/PP | 40/58 | 19 | 505 | 253 | [51] |
WF/PP/ZB | 40/58/10 | 22 | 402 | 237 | [51] |
WF/PP | 40/60 | 19 | 535 | 319 | [47] |
WF/PP/BA-BX | 37/57/4 | 20 | 465 | 318 | [47] |
WF/PE | 50/45 | 25 | 505 | 373 | [52] |
WF/PE/ZB | 50/35/10 | 26 | 320 | 255 | [52] |
WF/HDPE | 40/60 | 26 | 516 | 319 | [46] |
WF/HDPE/BA-BX | 37/57/4 | 25 | 510 | 320 | [46] |
WF/PVC | 35/58 | 26 | 160 | 49 | [53] |
WF/PVC/ZB | 35/58/6 | 27 | 209 | 43 | [53] |
Results of cone calorimeter for polyolefin-based WPC with various boron-based flame retardants.
Metal hydroxides can consume a significant amount of heat energy from the surroundings as well as release water during thermal decomposition [55]. Magnesium hydroxide (MH) and aluminum trihydroxide (ATH) are two commonly used flame retardants in PP-based WPCs. Table 3 lists the cone calorimetry testing results for WPC containing these metal hydroxides. The flame retardance of the WFC samples with varying weight ratios of WF, PP, and MH were different. Compared to the control samples, both WFC samples containing MH and AHH demonstrated a noticeable improvement in their flame resistance due to higher TTI and lower pHRR and THR values compared to the WFC samples without MH and AHH.
WPC samples | Weight ratio | TTI (s) | pHHR (kW/m2) | THR (MJ/m2) | Reference |
---|---|---|---|---|---|
WF/PP | 40/58 | 19 | 505 | 253 | [51] |
WF/PP/MH | 40/48/10 | 25 | 407 | 249 | [51] |
WF/PP | 50/46.7 | 21 | 563 | 93 | [56] |
WF/PP/ATH | 50/36.7/10 | 25 | 467 | 99 | [56] |
WF/PP | 50/43 | 28 | 395 | 162 | [57] |
WF/PP/ATH | 40/43/10 | 30 | 336 | 152 | [57] |
Results of cone calorimeter for polyolefin-based WPC with various metal hydroxide flame retardants.
Expandable graphite (EG) is a layered crystal consisting of sheets of carbon atoms tightly bound to each other. Some chemicals, such as sulfuric acid and potassium permanganate, can be inserted into the carbon layers of graphite. When subjected to heat, EG can expand up to 300 times compared to its original volume, which produces an insulating layer that can provide excellent flame resistance for WPCs [58]. EG appeared to be more effective for the polymer component of WPCs than the WF component when the weight ratios of the two varied from 60:40 to 40:60 (Table 4). Furthermore, EG exhibited the best flame retardance for PP-based WPC, with the lowest pHRR and THR values, compared to all the flame retardants mentioned above.
WPC samples | Weight ratio | TTI (s) | pHHR (kW/m2) | THR (MJ/m2) | Reference |
---|---|---|---|---|---|
WF/PP | 60/40 | 21 | 358 | 87 | [45] |
WF/PP/EG | 60/40/20 | 32 | 181 | 64 | [45] |
WF/PP | 40/60 | 20 | 390 | 90 | [59] |
WF/PP/EG | 40/60/25 | 24 | 99 | 39 | [59] |
WF/PP | 60/40 | 28 | 358 | 102 | [60] |
WF/PP/EG | 60/40/25 | 23 | 84 | 48 | [60] |
Results of cone calorimeter for PP-based WPC with expandable graphite flame retardants.
While all WPC samples containing individual flame retardants displayed decreased pHRR and THR values, they still demonstrated limited effectiveness under the mandatory flame condition. In the future, the development of flame retardants for WPCs will be more focused on the synergism between multiple components to further improve the flame retardance and the interfacial compatibility in the compound system. Intumescent flame retardants (IRFs), which consist of a char-forming agent, dehydrating agent, and blowing agent, have attracted significant attention because of their environmental friendliness and high efficiency [61]. However, moisture absorption and incompatibility with polymers are potential drawbacks for blowing agents and carbonic sources. Therefore, novel flame retardants that are nontoxic, have excellent flame resistance, and are highly compatible with polymers should be developed in the future.
Wood plastic composites has a significant potential and brilliant prospect in the application of building construction. WPC products like sidings, ceilings, windows, and floorings with the special advantages in environmental protection and sustainable development can effectively promote the coordinated development of wood-based engineering products in the “next-generation” green construction. However, the main defects on low mechanical properties, weak biological and aging resistance and poor flame retardance limit its further development. The novel modification ways including the selection of wood species, alloy reinforcement and synergistic improvement on flame resistance can be used to effectively facilitate the promotion of comprehensive properties of WPC, which achieves to the related requirements in the field of building construction. Future works also should focus on these necessary problems. In addition, the coextrusion technology with solid woods, functional polymers or metals is also a promising modification method for engineered WPC for construction in the future.
This work is supported by the following grants and programs: 1. National Natural Science Foundation of China (32060381); 2. Yunnan Provincial Applied and Basic Research Grants (2019FB067); 3. Ten-thousand Program Youth Talent Support Program (2020); 4. “111” project.
There is no conflict of interest in this field.
IntechOpen - where academia and industry create content with global impact
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\\n\\nCo-founded by Alex Lazinica and Vedran Kordic: “We are passionate about the advancement of science. As Ph.D. researchers in Vienna, we found it difficult to access the scholarly research we needed. We created IntechOpen with the specific aim of putting the academic needs of the global research community before the business interests of publishers. Our Team is now a global one and includes highly-renowned scientists and publishers, as well as experts in disseminating your research.”
\\n\\nBut, one thing we have in common is -- we are all scientists at heart!
\\n\\nSara Uhac, COO
\\n\\nSara Uhac was appointed Managing Director of IntechOpen at the beginning of 2014. She directs and controls the company’s operations. Sara joined IntechOpen in 2010 as Head of Journal Publishing, a new strategically underdeveloped department at that time. After obtaining a Master's degree in Media Management, she completed her Ph.D. at the University of Lugano, Switzerland. She holds a BA in Financial Market Management from the Bocconi University in Milan, Italy, where she started her career in the American publishing house Condé Nast and further collaborated with the UK-based publishing company Time Out. Sara was awarded a professional degree in Publishing from Yale University (2012). She is a member of the professional branch association of "Publishers, Designers and Graphic Artists" at the Croatian Chamber of Commerce.
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\\n\\nAdrian Assad De Marco joined the company as a Director in 2017. With his extensive experience in management, acquired while working for regional and global leaders, he took over direction and control of all the company's publishing processes. Adrian holds a degree in Economy and Management from the University of Zagreb, School of Economics, Croatia. A former sportsman, he continually strives to develop his skills through professional courses and specializations such as NLP (Neuro-linguistic programming).
\\n\\nDr Alex Lazinica
\\n\\nAlex Lazinica is co-founder and Board member of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his Ph.D. in Robotics at the Vienna University of Technology. There, he worked as a robotics researcher with the university's Intelligent Manufacturing Systems Group, as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and, most importantly, co-founded and built the International Journal of Advanced Robotic Systems, the world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career since it proved to be the pathway to the foundation of IntechOpen with its focus on addressing academic researchers’ needs. Alex personifies many of IntechOpen´s key values, including the commitment to developing mutual trust, openness, and a spirit of entrepreneurialism. Today, his focus is on defining the growth and development strategy for the company.
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\n\nBut, one thing we have in common is -- we are all scientists at heart!
\n\nSara Uhac, COO
\n\nSara Uhac was appointed Managing Director of IntechOpen at the beginning of 2014. She directs and controls the company’s operations. Sara joined IntechOpen in 2010 as Head of Journal Publishing, a new strategically underdeveloped department at that time. After obtaining a Master's degree in Media Management, she completed her Ph.D. at the University of Lugano, Switzerland. She holds a BA in Financial Market Management from the Bocconi University in Milan, Italy, where she started her career in the American publishing house Condé Nast and further collaborated with the UK-based publishing company Time Out. Sara was awarded a professional degree in Publishing from Yale University (2012). She is a member of the professional branch association of "Publishers, Designers and Graphic Artists" at the Croatian Chamber of Commerce.
\n\nAdrian Assad De Marco
\n\nAdrian Assad De Marco joined the company as a Director in 2017. With his extensive experience in management, acquired while working for regional and global leaders, he took over direction and control of all the company's publishing processes. Adrian holds a degree in Economy and Management from the University of Zagreb, School of Economics, Croatia. A former sportsman, he continually strives to develop his skills through professional courses and specializations such as NLP (Neuro-linguistic programming).
\n\nDr Alex Lazinica
\n\nAlex Lazinica is co-founder and Board member of IntechOpen. After obtaining a Master's degree in Mechanical Engineering, he continued his Ph.D. in Robotics at the Vienna University of Technology. There, he worked as a robotics researcher with the university's Intelligent Manufacturing Systems Group, as well as a guest researcher at various European universities, including the Swiss Federal Institute of Technology Lausanne (EPFL). During this time he published more than 20 scientific papers, gave presentations, served as a reviewer for major robotic journals and conferences and, most importantly, co-founded and built the International Journal of Advanced Robotic Systems, the world's first Open Access journal in the field of robotics. Starting this journal was a pivotal point in his career since it proved to be the pathway to the foundation of IntechOpen with its focus on addressing academic researchers’ needs. Alex personifies many of IntechOpen´s key values, including the commitment to developing mutual trust, openness, and a spirit of entrepreneurialism. Today, his focus is on defining the growth and development strategy for the company.
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Firstenberg"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10207",title:"Sexual Abuse",subtitle:"An Interdisciplinary Approach",isOpenForSubmission:!1,hash:"e1ec1d5a7093490df314d7887e0b3809",slug:"sexual-abuse-an-interdisciplinary-approach",bookSignature:"Ersi Kalfoğlu and Sotirios Kalfoglou",coverURL:"https://cdn.intechopen.com/books/images_new/10207.jpg",editedByType:"Edited by",editors:[{id:"68678",title:"Dr.",name:"Ersi",middleName:null,surname:"Kalfoglou",slug:"ersi-kalfoglou",fullName:"Ersi Kalfoglou"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:302,seriesByTopicCollection:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:23,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:12,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],seriesByTopicTotal:3,mostCitedChapters:[{id:"42656",doi:"10.5772/55538",title:"Conceptual Frameworks of Vulnerability Assessments for Natural Disasters Reduction",slug:"conceptual-frameworks-of-vulnerability-assessments-for-natural-disasters-reduction",totalDownloads:10042,totalCrossrefCites:18,totalDimensionsCites:75,abstract:null,book:{id:"3054",slug:"approaches-to-disaster-management-examining-the-implications-of-hazards-emergencies-and-disasters",title:"Approaches to Disaster Management",fullTitle:"Approaches to Disaster Management - Examining the Implications of Hazards, Emergencies and Disasters"},signatures:"Roxana L. Ciurean, Dagmar Schröter and Thomas Glade",authors:[{id:"163703",title:"Prof.",name:"Thomas",middleName:null,surname:"Glade",slug:"thomas-glade",fullName:"Thomas Glade"},{id:"164141",title:"Ph.D. Student",name:"Roxana",middleName:"Liliana",surname:"Ciurean",slug:"roxana-ciurean",fullName:"Roxana Ciurean"},{id:"164142",title:"Dr.",name:"Dagmar",middleName:null,surname:"Schroeter",slug:"dagmar-schroeter",fullName:"Dagmar Schroeter"}]},{id:"58010",doi:"10.5772/intechopen.72304",title:"Fourth Industrial Revolution: Current Practices, Challenges, and Opportunities",slug:"fourth-industrial-revolution-current-practices-challenges-and-opportunities",totalDownloads:6445,totalCrossrefCites:44,totalDimensionsCites:70,abstract:"The globalization and the competitiveness are forcing companies to rethink and to innovate their production processes following the so-called Industry 4.0 paradigm. It represents the integration of tools already used in the past (big data, cloud, robot, 3D printing, simulation, etc.) that are now connected into a global network by transmitting digital data. The implementation of this new paradigm represents a huge change for companies, which are faced with big investments. In order to benefit from the opportunities offered by the smart revolution, companies must have the prerequisites needed to withstand changes generated by “smart” system. In addition, new workers who face the world of work 4.0 must have new skills in automation, digitization, and information technology, without forgetting soft skills. This chapter aims to present the main good practices, challenges, and opportunities related to Industry 4.0 paradigm.",book:{id:"6291",slug:"digital-transformation-in-smart-manufacturing",title:"Digital Transformation in Smart Manufacturing",fullTitle:"Digital Transformation in Smart Manufacturing"},signatures:"Antonella Petrillo, Fabio De Felice, Raffaele Cioffi and Federico\nZomparelli",authors:[{id:"161682",title:"Prof.",name:"Fabio",middleName:null,surname:"De Felice",slug:"fabio-de-felice",fullName:"Fabio De Felice"},{id:"181603",title:"Dr.",name:"Antonella",middleName:null,surname:"Petrillo",slug:"antonella-petrillo",fullName:"Antonella Petrillo"},{id:"205141",title:"Dr.",name:"Federico",middleName:null,surname:"Zomparelli",slug:"federico-zomparelli",fullName:"Federico Zomparelli"},{id:"208748",title:"Dr.",name:"Raffaele",middleName:null,surname:"Cioffi",slug:"raffaele-cioffi",fullName:"Raffaele Cioffi"}]},{id:"35715",doi:"10.5772/38693",title:"The Role and Importance of Cultural Tourism in Modern Tourism Industry",slug:"the-role-and-importance-of-cultural-tourism-in-modern-tourism-industry",totalDownloads:41085,totalCrossrefCites:31,totalDimensionsCites:62,abstract:null,book:{id:"2298",slug:"strategies-for-tourism-industry-micro-and-macro-perspectives",title:"Strategies for Tourism Industry",fullTitle:"Strategies for Tourism Industry - Micro and Macro Perspectives"},signatures:"Janos Csapo",authors:[{id:"118766",title:"Dr.",name:"János",middleName:null,surname:"Csapó",slug:"janos-csapo",fullName:"János Csapó"}]},{id:"38973",doi:"10.5772/51460",title:"Risk Management in Construction Projects",slug:"risk-management-in-construction-projects",totalDownloads:102568,totalCrossrefCites:36,totalDimensionsCites:59,abstract:null,book:{id:"2175",slug:"risk-management-current-issues-and-challenges",title:"Risk Management",fullTitle:"Risk Management - Current Issues and Challenges"},signatures:"Nerija Banaitiene and Audrius Banaitis",authors:[{id:"139414",title:"Dr.",name:"Nerija",middleName:null,surname:"Banaitiene",slug:"nerija-banaitiene",fullName:"Nerija Banaitiene"},{id:"149658",title:"Dr.",name:"Audrius",middleName:null,surname:"Banaitis",slug:"audrius-banaitis",fullName:"Audrius Banaitis"}]},{id:"40977",doi:"10.5772/53885",title:"The Emergence of Scientific Reasoning",slug:"the-emergence-of-scientific-reasoning",totalDownloads:4554,totalCrossrefCites:8,totalDimensionsCites:59,abstract:null,book:{id:"654",slug:"current-topics-in-children-s-learning-and-cognition",title:"Current Topics in Children's Learning and Cognition",fullTitle:"Current Topics in Children's Learning and Cognition"},signatures:"Bradley J. Morris, Steve Croker, Amy M. Masnick and Corinne Zimmerman",authors:[{id:"154336",title:"Prof.",name:"Bradley",middleName:null,surname:"Morris",slug:"bradley-morris",fullName:"Bradley Morris"},{id:"154337",title:"Prof.",name:"Steve",middleName:null,surname:"Croker",slug:"steve-croker",fullName:"Steve Croker"},{id:"154338",title:"Prof.",name:"Amy",middleName:null,surname:"Masnick",slug:"amy-masnick",fullName:"Amy Masnick"},{id:"154339",title:"Prof.",name:"Corinne",middleName:null,surname:"Zimmerman",slug:"corinne-zimmerman",fullName:"Corinne Zimmerman"}]}],mostDownloadedChaptersLast30Days:[{id:"58890",title:"Philosophy and Paradigm of Scientific Research",slug:"philosophy-and-paradigm-of-scientific-research",totalDownloads:14074,totalCrossrefCites:9,totalDimensionsCites:17,abstract:"Before carrying out the empirical analysis of the role of management culture in corporate social responsibility, identification of the philosophical approach and the paradigm on which the research carried out is based is necessary. Therefore, this chapter deals with the philosophical systems and paradigms of scientific research, the epistemology, evaluating understanding and application of various theories and practices used in the scientific research. The key components of the scientific research paradigm are highlighted. Theories on the basis of which this research was focused on identification of the level of development of the management culture in order to implement corporate social responsibility are identified, and the stages of its implementation are described.",book:{id:"5791",slug:"management-culture-and-corporate-social-responsibility",title:"Management Culture and Corporate Social Responsibility",fullTitle:"Management Culture and Corporate Social Responsibility"},signatures:"Pranas Žukauskas, Jolita Vveinhardt and Regina Andriukaitienė",authors:[{id:"179629",title:"Prof.",name:"Jolita",middleName:null,surname:"Vveinhardt",slug:"jolita-vveinhardt",fullName:"Jolita Vveinhardt"}]},{id:"74550",title:"School Conflicts: Causes and Management Strategies in Classroom Relationships",slug:"school-conflicts-causes-and-management-strategies-in-classroom-relationships",totalDownloads:2328,totalCrossrefCites:1,totalDimensionsCites:10,abstract:"Conflicts cannot cease to exist, as they are intrinsic to human beings, forming an integral part of their moral and emotional growth. Likewise, they exist in all schools. The school is inserted in a space where the conflict manifests itself daily and assumes relevance, being the result of the multiple interpersonal relationships that occur in the school context. Thus, conflict is part of school life, which implies that teachers must have the skills to manage conflict constructively. Recognizing the diversity of school conflicts, this chapter aimed to present its causes, highlighting the main ones in the classroom, in the teacher-student relationship. It is important to conflict face and resolve it with skills to manage it properly and constructively, establishing cooperative relationships, and producing integrative solutions. Harmony and appreciation should coexist in a classroom environment and conflict should not interfere, negatively, in the teaching and learning process. This bibliography review underscore the need for during the teachers’ initial training the conflict management skills development.",book:{id:"7827",slug:"interpersonal-relationships",title:"Interpersonal Relationships",fullTitle:"Interpersonal Relationships"},signatures:"Sabina Valente, Abílio Afonso Lourenço and Zsolt Németh",authors:[{id:"324514",title:"Ph.D.",name:"Sabina",middleName:"N.",surname:"Valente",slug:"sabina-valente",fullName:"Sabina Valente"},{id:"326375",title:"Ph.D.",name:"Abílio",middleName:"Afonso",surname:"Lourenço",slug:"abilio-lourenco",fullName:"Abílio Lourenço"},{id:"329177",title:"Dr.",name:"Zsolt",middleName:null,surname:"Németh",slug:"zsolt-nemeth",fullName:"Zsolt Németh"}]},{id:"58969",title:"Corruption, Causes and Consequences",slug:"corruption-causes-and-consequences",totalDownloads:27687,totalCrossrefCites:13,totalDimensionsCites:15,abstract:"Corruption is a constant in the society and occurs in all civilizations; however, it has only been in the past 20 years that this phenomenon has begun being seriously explored. It has many different shapes as well as many various effects, both on the economy and the society at large. Among the most common causes of corruption are the political and economic environment, professional ethics and morality and, of course, habits, customs, tradition and demography. Its effects on the economy (and also on the wider society) are well researched, yet still not completely. Corruption thus inhibits economic growth and affects business operations, employment and investments. It also reduces tax revenue and the effectiveness of various financial assistance programs. The wider society is influenced by a high degree of corruption in terms of lowering of trust in the law and the rule of law, education and consequently the quality of life (access to infrastructure, health care). There also does not exist an unambiguous answer as to how to deal with corruption. Something that works in one country or in one region will not necessarily be successful in another. This chapter tries to answer at least a few questions about corruption and the causes for it, its consequences and how to deal with it successfully.",book:{id:"6487",slug:"trade-and-global-market",title:"Trade and Global Market",fullTitle:"Trade and Global Market"},signatures:"Štefan Šumah",authors:[{id:"228073",title:"Mr.",name:"Stefan",middleName:null,surname:"Sumah",slug:"stefan-sumah",fullName:"Stefan Sumah"}]},{id:"55499",title:"Human Resources Management in Nonprofit Organizations: A Case Study of Istanbul Foundation for Culture and Arts",slug:"human-resources-management-in-nonprofit-organizations-a-case-study-of-istanbul-foundation-for-cultur",totalDownloads:2399,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The aim of this study is to investigate the efficiency and importance of human resources management in nonprofit organizations. The understanding was included to the literature as personnel management at the beginning of the twentieth century and it turned into an approach as human resources management in the 1980s. It could be observed that many organizations, which deem the human as the most critical stakeholder, adopt a traditional way of personnel management in operating human resources. The employees play a key role in the success of an organization. For this reason, subjects such as recruitment, training, development, career management, performance appraisal, occupational health, and safety are the fundamental functions of human resources management. The study examines to what extent these roles are evaluated through a case study. The subject matter of the study is the most powerful culture and art foundation in Turkey. Compared to many other nonprofit organizations, the foundation actively performs a variety of services within a year worldwide. The fact that the total number of employees might rise up to 800, including the field personnel, indicates the need of a good functioning human resources management. The human resources practices of the foundation are examined and evaluated within that scope.",book:{id:"5826",slug:"issues-of-human-resource-management",title:"Issues of Human Resource Management",fullTitle:"Issues of Human Resource Management"},signatures:"Beste Gökçe Parsehyan",authors:[{id:"189113",title:"Dr.",name:"Beste",middleName:null,surname:"Gokce Parsehyan",slug:"beste-gokce-parsehyan",fullName:"Beste Gokce Parsehyan"}]},{id:"59152",title:"Marketing Strategies for the Social Good",slug:"marketing-strategies-for-the-social-good",totalDownloads:1669,totalCrossrefCites:1,totalDimensionsCites:1,abstract:"Social network sites (SNS) have proven to be a good environment to promote and sell goods and services, but marketing is more than creating commercial strategies. Social marketing strategies can also be used to promote behavioral change and help individuals transform their lives, achieve well-being, and adopt prosocial behaviors. In this chapter, we seek to analyze with a netnographic study, how SNS are being employed by nonprofits and nongovernment organizations (NGOs) to enable citizens and consumers to participate in different programs and activities that promote social transformation and well-being. A particular interest is to identify how organizations are using behavioral economic tactics to nudge individuals and motivate them to engage in prosocial actions. By providing an understanding on how SNS can provide an adequate environment for the design of social marketing strategies, we believe our work has practical implications both for academicians and marketers who want to contribute in the transformation of consumer behavior and the achievement of well-being and social change.",book:{id:"6583",slug:"marketing",title:"Marketing",fullTitle:"Marketing"},signatures:"Alicia De La Pena",authors:[{id:"196878",title:"Dr.",name:"Alicia",middleName:null,surname:"De La Pena",slug:"alicia-de-la-pena",fullName:"Alicia De La Pena"}]}],onlineFirstChaptersFilter:{topicId:"4",limit:6,offset:0},onlineFirstChaptersCollection:[{id:"83040",title:"Corporate Social Responsibility and Social Report: A Case Study in the Basque Country",slug:"corporate-social-responsibility-and-social-report-a-case-study-in-the-basque-country",totalDownloads:1,totalDimensionsCites:null,doi:"10.5772/intechopen.105511",abstract:"This chapter illustrates the case of the Spanish company Telefónica SA, a world leader in the telecommunication industry. The main research question is to understand if social responsibility can play a main role in an uncertain scenario. Or better, understand how Corporate Social Responsibility (CSR) can be organized, managed, and measured to be considered a sustainable choice detached from any greenwashing policy. In terms of the socioeconomic environment with the combination of external social and economic conditions that influence the operation and preformation of an organization, the company should be a system not only capable of generating profits but at the same time contributing to society and environmental protection, integrating social responsibility as a strategic investment in the framework of their competitive strategy, in their management tools and their operations. The analysis of this case study aims to offer a model of CSR analysis and measurement tools such as the social report for managers who will have to face the important challenges of sustainable growth in compliance with the 2030 Agenda and SDGs paradigm (Sustainable Development Goals).",book:{id:"11602",title:"Corporate Social Responsibility",coverURL:"https://cdn.intechopen.com/books/images_new/11602.jpg"},signatures:"Vincenzo Basile"},{id:"82771",title:"Making Sense of a Biochemistry Learning Process and Teacher’s Empathy: Computer-Supported Collaborative Learning Using Emoji Symbols",slug:"making-sense-of-a-biochemistry-learning-process-and-teacher-s-empathy-computer-supported-collaborati",totalDownloads:2,totalDimensionsCites:null,doi:"10.5772/intechopen.105927",abstract:"Teaching biochemistry concepts can be a challenging task, as it requires learners and teachers to integrate abstract concepts from chemistry and biology. Students struggle to grasp the molecular processes, as they find it difficult to visualize them. Incorporating Information Communication Technology (ICT) implementations during lessons is known to encourage learners’ involvement in a collaborative learning process and is especially effective when training preservice teachers (PSTs). In the current study, we describe an example in which the teacher plays an important role in creating the Computer-Supported Collaborative Learning (CSCL) in this environment to encourage peer learning while coping with complicated material. We believe that one of the important components in guiding such peer work is the teacher’s ability to sense each group’s progress and to employ empathy in the classroom as a tool for coping with the difficulty and challenge of acquiring new knowledge and for creating a productive dialog between groups that disagree. In this example, the process of Information Communication Technology (ICT) implementation encouraged the preservice teachers (PSTs) to create an alternative set of symbols, which eventually served as a “language” and help them understand the biochemical processes.",book:{id:"11443",title:"Empathy - Advanced Research and Applications",coverURL:"https://cdn.intechopen.com/books/images_new/11443.jpg"},signatures:"Dana Sachyani and Ilana Ronen"},{id:"83112",title:"Anomalies in Nigeria Presidential Election Data and the Way Forward",slug:"anomalies-in-nigeria-presidential-election-data-and-the-way-forward",totalDownloads:0,totalDimensionsCites:0,doi:"10.5772/intechopen.106657",abstract:"Nigeria presently runs a presidential system of government and the Independent National Electoral Commission (INEC) is saddled with the responsibility of conducting elections, every four years. A fraud-free and credible election is a necessary ingredient to the growth of democracy. However, election fraud has become a major challenge in the Nigerian political system. Till date, reports show that elections in Nigeria have been marred with vote buying, falsification of results, underage voting, and the use of security forces to intimidate voters, among others. Hence, the authors suggest the need for transparency in the voting process and in the collation of results. There is also a need for an electoral reform to address the issue of electronic voting and electronic transmission of results. Electronic voting should be supported and encouraged by all stakeholders. The INEC, executive and legislative arms of government are advised to work in tandem to provide credible electoral process and improve on the conducts of elections in Nigeria. The chapter concludes with suggestion on the possibility of adopting election forensic techniques to address anomalies in Nigeria electoral results. The authors believe that this chapter contribution will be of great benefit to Nigeria and Africa as a whole.",book:{id:"11435",title:"Election and Democracy in the Digital Age - Status, Challenges, and Trends",coverURL:"https://cdn.intechopen.com/books/images_new/11435.jpg"},signatures:"Sunday Tunmibi and Wole Olatokun"},{id:"83121",title:"Social Media and Democracy",slug:"social-media-and-democracy",totalDownloads:0,totalDimensionsCites:null,doi:"10.5772/intechopen.106660",abstract:"The purpose of this chapter is to analyze the implications of freedom of speech regarding political discussions on social media platforms, such as Facebook. The paper will look at the following aspects: the occasion when social media users have to discuss politics as a hobby and as a means to keep their ideas out of the view of face-to-face social circles, to engage in social issues and even be part of protests, to discuss politicians’ public image, and attempt to change some users’ perception about it. Within social media, we witness debates or simple displays of emotions, allowing users to speak their minds and interact with other users, showing empathy toward them. The benefits of this are related to the therapeutic effects of speaking about what upsets them or angers them and finding like-minded users.",book:{id:"11435",title:"Election and Democracy in the Digital Age - Status, Challenges, and Trends",coverURL:"https://cdn.intechopen.com/books/images_new/11435.jpg"},signatures:"Irina-Ana Drobot"},{id:"83113",title:"Agoraphobic Dispositions towards Action Research: Teacher Education Students’ Perceptions and Experiences",slug:"agoraphobic-dispositions-towards-action-research-teacher-education-students-perceptions-and-experien",totalDownloads:3,totalDimensionsCites:0,doi:"10.5772/intechopen.106188",abstract:"One of the contemporary global education thrusts in teacher education is the generation of context-based theory through engagement in action research. While practicing in the classroom, the teacher education student is essentially in the laboratory creating procedural knowledge. Action research in the classroom involves reflective practice, which is indispensable to praxis. Despite the efficacy of action research in facilitating mathetics (learning how to learn), there are some militating situations that are fuelled by diehard traditional perceptions and practices. An exploration of teacher education students’ perceptions and experiences with action research was done with 16 informants who were selected purposively and exposed to in-depth interviews. The data were thematically analyzed and the findings were that some students develop agoraphobic dispositions toward action research due to some miseducative experiences that are largely attributed to traditional educational practices. The teacher education students are exposed to vices like technical rationality instead they should be oriented toward epistemic and pragmatic rationalities that are the linchpins of professional development. The experiences that precipitate agoraphobic dispositions in action research should be known and subsequently obliterated.",book:{id:"11481",title:"Active Learning - Research and Practice for STEAM and social sciences education",coverURL:"https://cdn.intechopen.com/books/images_new/11481.jpg"},signatures:"Davison Zireva"},{id:"83099",title:"Values-Flow in Contextual Psychotherapy: The ‘What’, ‘Why’, and ‘How’ of Sustainable Values-Based Behaviour",slug:"values-flow-in-contextual-psychotherapy-the-what-why-and-how-of-sustainable-values-based-behaviour",totalDownloads:6,totalDimensionsCites:0,doi:"10.5772/intechopen.106594",abstract:"Flow - enjoyed and fully absorbed engagement in meaningful and contextually bounded activities - is widely underutilised in psychotherapy and mental health settings. Two gold standard therapies, Acceptance and Commitment Therapy (ACT) and Dialectical Behaviour Therapy (DBT), while powerful and effective in many ways, would benefit from systematic models that move from initiating positive change to sustaining meaningful change. This chapter introduces ‘Values-Flow’ – an approach aimed at building commitment and sustainable engagement in psychotherapy and values-based behaviour in working adults struggling with sub-optimal functioning. We first introduce Values-Flow and describe how it may benefit psychotherapy skills practice in everyday life. Next, we discuss why Values-Flow is relevant and enhances the practice of ACT and DBT strategies, helping to sustain engagement and creative practice of values-based actions outside of sessions. We then describe the ‘Values-Flow’ framework, which incorporates VIVA (Virtue, Involve, Vital, Accepting) and ARIA (Attend, Reflect, Inform, Act) tools that develop commitment for values-based practice in daily life. We conclude with a case-example of how Values-Flow can build commitment and sustainable engagement in homework completion in psychotherapy.",book:{id:"11444",title:"Happiness - Biopsychosocial and Anthropological Perspectives",coverURL:"https://cdn.intechopen.com/books/images_new/11444.jpg"},signatures:"Cedomir Ignjatovic, Margaret L. Kern and Lindsay G. 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He has been listed among the top 2% of scientists in the world for the last three consecutive years, 2019 to 2021 as per studies conducted by the Stanford University, USA.",institutionString:"Praxis Business School",institution:null},{id:"320071",title:"Dr.",name:"Sidra",middleName:null,surname:"Mehtab",slug:"sidra-mehtab",fullName:"Sidra Mehtab",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00002v6KHoQAM/Profile_Picture_1584512086360",biography:"Sidra Mehtab has completed her BS with honors in Physics from Calcutta University, India in 2018. She has done MS in Data Science and Analytics from Maulana Abul Kalam Azad University of Technology (MAKAUT), Kolkata, India in 2020. Her research areas include Econometrics, Time Series Analysis, Machine Learning, Deep Learning, Artificial Intelligence, and Computer and Network Security with a particular focus on Cyber Security Analytics. 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Currently, she is working as a Data Scientist with an MNC in Delhi, India.",institutionString:"NSHM College of Management and Technology",institution:{name:"Association for Computing Machinery",country:{name:"United States of America"}}},{id:"226240",title:"Dr.",name:"Andri Irfan",middleName:null,surname:"Rifai",slug:"andri-irfan-rifai",fullName:"Andri Irfan Rifai",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/226240/images/7412_n.jpg",biography:"Andri IRFAN is a Senior Lecturer of Civil Engineering and Planning. He completed the PhD at the Universitas Indonesia & Universidade do Minho with Sandwich Program Scholarship from the Directorate General of Higher Education and LPDP scholarship. He has been teaching for more than 19 years and much active to applied his knowledge in the project construction in Indonesia. His research interest ranges from pavement management system to advanced data mining techniques for transportation engineering. He has published more than 50 papers in journals and 2 books.",institutionString:null,institution:{name:"Universitas Internasional Batam",country:{name:"Indonesia"}}},{id:"314576",title:"Dr.",name:"Ibai",middleName:null,surname:"Laña",slug:"ibai-lana",fullName:"Ibai Laña",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314576/images/system/314576.jpg",biography:"Dr. Ibai Laña works at TECNALIA as a data analyst. He received his Ph.D. in Artificial Intelligence from the University of the Basque Country (UPV/EHU), Spain, in 2018. He is currently a senior researcher at TECNALIA. His research interests fall within the intersection of intelligent transportation systems, machine learning, traffic data analysis, and data science. He has dealt with urban traffic forecasting problems, applying machine learning models and evolutionary algorithms. He has experience in origin-destination matrix estimation or point of interest and trajectory detection. Working with large volumes of data has given him a good command of big data processing tools and NoSQL databases. He has also been a visiting scholar at the Knowledge Engineering and Discovery Research Institute, Auckland University of Technology.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"314575",title:"Dr.",name:"Jesus",middleName:null,surname:"L. Lobo",slug:"jesus-l.-lobo",fullName:"Jesus L. Lobo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/314575/images/system/314575.png",biography:"Dr. Jesús López is currently based in Bilbao (Spain) working at TECNALIA as Artificial Intelligence Research Scientist. In most cases, a project idea or a new research line needs to be investigated to see if it is good enough to take into production or to focus on it. That is exactly what he does, diving into Machine Learning algorithms and technologies to help TECNALIA to decide whether something is great in theory or will actually impact on the product or processes of its projects. So, he is expert at framing experiments, developing hypotheses, and proving whether they’re true or not, in order to investigate fundamental problems with a longer time horizon. He is also able to design and develop PoCs and system prototypes in simulation. He has participated in several national and internacional R&D projects.\n\nAs another relevant part of his everyday research work, he usually publishes his findings in reputed scientific refereed journals and international conferences, occasionally acting as reviewer and Programme Commitee member. Concretely, since 2018 he has published 9 JCR (8 Q1) journal papers, 9 conference papers (e.g. ECML PKDD 2021), and he has co-edited a book. He is also active in popular science writing data science stories for reputed blogs (KDNuggets, TowardsDataScience, Naukas). Besides, he has recently embarked on mentoring programmes as mentor, and has also worked as data science trainer.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"103779",title:"Prof.",name:"Yalcin",middleName:null,surname:"Isler",slug:"yalcin-isler",fullName:"Yalcin Isler",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRyQ8QAK/Profile_Picture_1628834958734",biography:"Yalcin Isler (1971 - Burdur / Turkey) received the B.Sc. degree in the Department of Electrical and Electronics Engineering from Anadolu University, Eskisehir, Turkey, in 1993, the M.Sc. degree from the Department of Electronics and Communication Engineering, Suleyman Demirel University, Isparta, Turkey, in 1996, the Ph.D. degree from the Department of Electrical and Electronics Engineering, Dokuz Eylul University, Izmir, Turkey, in 2009, and the Competence of Associate Professorship from the Turkish Interuniversity Council in 2019.\n\nHe was Lecturer at Burdur Vocational School in Suleyman Demirel University (1993-2000, Burdur / Turkey), Software Engineer (2000-2002, Izmir / Turkey), Research Assistant in Bulent Ecevit University (2002-2003, Zonguldak / Turkey), Research Assistant in Dokuz Eylul University (2003-2010, Izmir / Turkey), Assistant Professor at the Department of Electrical and Electronics Engineering in Bulent Ecevit University (2010-2012, Zonguldak / Turkey), Assistant Professor at the Department of Biomedical Engineering in Izmir Katip Celebi University (2012-2019, Izmir / Turkey). He is an Associate Professor at the Department of Biomedical Engineering at Izmir Katip Celebi University, Izmir / Turkey, since 2019. In addition to academics, he has also founded Islerya Medical and Information Technologies Company, Izmir / Turkey, since 2017.\n\nHis main research interests cover biomedical signal processing, pattern recognition, medical device design, programming, and embedded systems. He has many scientific papers and participated in several projects in these study fields. He was an IEEE Student Member (2009-2011) and IEEE Member (2011-2014) and has been IEEE Senior Member since 2014.",institutionString:null,institution:{name:"Izmir Kâtip Çelebi University",country:{name:"Turkey"}}},{id:"339677",title:"Dr.",name:"Mrinmoy",middleName:null,surname:"Roy",slug:"mrinmoy-roy",fullName:"Mrinmoy Roy",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/339677/images/16768_n.jpg",biography:"An accomplished Sales & Marketing professional with 12 years of cross-functional experience in well-known organisations such as CIPLA, LUPIN, GLENMARK, ASTRAZENECA across different segment of Sales & Marketing, International Business, Institutional Business, Product Management, Strategic Marketing of HIV, Oncology, Derma, Respiratory, Anti-Diabetic, Nutraceutical & Stomatological Product Portfolio and Generic as well as Chronic Critical Care Portfolio. A First Class MBA in International Business & Strategic Marketing, B.Pharm, D.Pharm, Google Certified Digital Marketing Professional. Qualified PhD Candidate in Operations and Management with special focus on Artificial Intelligence and Machine Learning adoption, analysis and use in Healthcare, Hospital & Pharma Domain. Seasoned with diverse therapy area of Pharmaceutical Sales & Marketing ranging from generating revenue through generating prescriptions, launching new products, and making them big brands with continuous strategy execution at the Physician and Patients level. Moved from Sales to Marketing and Business Development for 3.5 years in South East Asian Market operating from Manila, Philippines. Came back to India and handled and developed Brands such as Gluconorm, Lupisulin, Supracal, Absolut Woman, Hemozink, Fabiflu (For COVID 19), and many more. In my previous assignment I used to develop and execute strategies on Sales & Marketing, Commercialization & Business Development for Institution and Corporate Hospital Business portfolio of Oncology Therapy Area for AstraZeneca Pharma India Ltd. Being a Research Scholar and Student of ‘Operations Research & Management: Artificial Intelligence’ I published several pioneer research papers and book chapters on the same in Internationally reputed journals and Books indexed in Scopus, Springer and Ei Compendex, Google Scholar etc. Currently, I am launching PGDM Pharmaceutical Management Program in IIHMR Bangalore and spearheading the course curriculum and structure of the same. I am interested in Collaboration for Healthcare Innovation, Pharma AI Innovation, Future trend in Marketing and Management with incubation on Healthcare, Healthcare IT startups, AI-ML Modelling and Healthcare Algorithm based training module development. I am also an affiliated member of the Institute of Management Consultant of India, looking forward to Healthcare, Healthcare IT and Innovation, Pharma and Hospital Management Consulting works.",institutionString:null,institution:{name:"Lovely Professional University",country:{name:"India"}}},{id:"1063",title:"Prof.",name:"Constantin",middleName:null,surname:"Volosencu",slug:"constantin-volosencu",fullName:"Constantin Volosencu",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/1063/images/system/1063.png",biography:"Prof. Dr. Constantin Voloşencu graduated as an engineer from\nPolitehnica University of Timișoara, Romania, where he also\nobtained a doctorate degree. He is currently a full professor in\nthe Department of Automation and Applied Informatics at the\nsame university. Dr. Voloşencu is the author of ten books, seven\nbook chapters, and more than 160 papers published in journals\nand conference proceedings. He has also edited twelve books and\nhas twenty-seven patents to his name. He is a manager of research grants, editor in\nchief and member of international journal editorial boards, a former plenary speaker, a member of scientific committees, and chair at international conferences. His\nresearch is in the fields of control systems, control of electric drives, fuzzy control\nsystems, neural network applications, fault detection and diagnosis, sensor network\napplications, monitoring of distributed parameter systems, and power ultrasound\napplications. He has developed automation equipment for machine tools, spooling\nmachines, high-power ultrasound processes, and more.",institutionString:'"Politechnica" University Timişoara',institution:null},{id:"221364",title:"Dr.",name:"Eneko",middleName:null,surname:"Osaba",slug:"eneko-osaba",fullName:"Eneko Osaba",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/221364/images/system/221364.jpg",biography:"Dr. Eneko Osaba works at TECNALIA as a senior researcher. He obtained his Ph.D. in Artificial Intelligence in 2015. He has participated in more than twenty-five local and European research projects, and in the publication of more than 130 papers. He has performed several stays at universities in the United Kingdom, Italy, and Malta. Dr. Osaba has served as a program committee member in more than forty international conferences and participated in organizing activities in more than ten international conferences. He is a member of the editorial board of the International Journal of Artificial Intelligence, Data in Brief, and Journal of Advanced Transportation. He is also a guest editor for the Journal of Computational Science, Neurocomputing, Swarm, and Evolutionary Computation and IEEE ITS Magazine.",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"275829",title:"Dr.",name:"Esther",middleName:null,surname:"Villar-Rodriguez",slug:"esther-villar-rodriguez",fullName:"Esther Villar-Rodriguez",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/275829/images/system/275829.jpg",biography:"Dr. Esther Villar obtained a Ph.D. in Information and Communication Technologies from the University of Alcalá, Spain, in 2015. She obtained a degree in Computer Science from the University of Deusto, Spain, in 2010, and an MSc in Computer Languages and Systems from the National University of Distance Education, Spain, in 2012. Her areas of interest and knowledge include natural language processing (NLP), detection of impersonation in social networks, semantic web, and machine learning. Dr. Esther Villar made several contributions at conferences and publishing in various journals in those fields. Currently, she is working within the OPTIMA (Optimization Modeling & Analytics) business of TECNALIA’s ICT Division as a data scientist in projects related to the prediction and optimization of management and industrial processes (resource planning, energy efficiency, etc).",institutionString:"TECNALIA Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"49813",title:"Dr.",name:"Javier",middleName:null,surname:"Del Ser",slug:"javier-del-ser",fullName:"Javier Del Ser",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/49813/images/system/49813.png",biography:"Prof. Dr. Javier Del Ser received his first PhD in Telecommunication Engineering (Cum Laude) from the University of Navarra, Spain, in 2006, and a second PhD in Computational Intelligence (Summa Cum Laude) from the University of Alcala, Spain, in 2013. He is currently a principal researcher in data analytics and optimisation at TECNALIA (Spain), a visiting fellow at the Basque Center for Applied Mathematics (BCAM) and a part-time lecturer at the University of the Basque Country (UPV/EHU). His research interests gravitate on the use of descriptive, prescriptive and predictive algorithms for data mining and optimization in a diverse range of application fields such as Energy, Transport, Telecommunications, Health and Industry, among others. In these fields he has published more than 240 articles, co-supervised 8 Ph.D. theses, edited 6 books, coauthored 7 patents and participated/led more than 40 research projects. He is a Senior Member of the IEEE, and a recipient of the Biscay Talent prize for his academic career.",institutionString:"Tecnalia Research & Innovation",institution:{name:"Tecnalia",country:{name:"Spain"}}},{id:"278948",title:"Dr.",name:"Carlos Pedro",middleName:null,surname:"Gonçalves",slug:"carlos-pedro-goncalves",fullName:"Carlos Pedro Gonçalves",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRcmyQAC/Profile_Picture_1564224512145",biography:'Carlos Pedro Gonçalves (PhD) is an Associate Professor at Lusophone University of Humanities and Technologies and a researcher on Complexity Sciences, Quantum Technologies, Artificial Intelligence, Strategic Studies, Studies in Intelligence and Security, FinTech and Financial Risk Modeling. He is also a progammer with programming experience in:\n\nA) Quantum Computing using Qiskit Python module and IBM Quantum Experience Platform, with software developed on the simulation of Quantum Artificial Neural Networks and Quantum Cybersecurity;\n\nB) Artificial Intelligence and Machine learning programming in Python;\n\nC) Artificial Intelligence, Multiagent Systems Modeling and System Dynamics Modeling in Netlogo, with models developed in the areas of Chaos Theory, Econophysics, Artificial Intelligence, Classical and Quantum Complex Systems Science, with the Econophysics models having been cited worldwide and incorporated in PhD programs by different Universities.\n\nReceived an Arctic Code Vault Contributor status by GitHub, due to having developed open source software preserved in the \\"Arctic Code Vault\\" for future generations (https://archiveprogram.github.com/arctic-vault/), with the Strategy Analyzer A.I. module for decision making support (based on his PhD thesis, used in his Classes on Decision Making and in Strategic Intelligence Consulting Activities) and QNeural Python Quantum Neural Network simulator also preserved in the \\"Arctic Code Vault\\", for access to these software modules see: https://github.com/cpgoncalves. He is also a peer reviewer with outsanding review status from Elsevier journals, including Physica A, Neurocomputing and Engineering Applications of Artificial Intelligence. Science CV available at: https://www.cienciavitae.pt//pt/8E1C-A8B3-78C5 and ORCID: https://orcid.org/0000-0002-0298-3974',institutionString:"University of Lisbon",institution:{name:"Universidade Lusófona",country:{name:"Portugal"}}},{id:"310576",title:"Prof.",name:"Erick Giovani",middleName:null,surname:"Sperandio Nascimento",slug:"erick-giovani-sperandio-nascimento",fullName:"Erick Giovani Sperandio Nascimento",position:null,profilePictureURL:"https://intech-files.s3.amazonaws.com/0033Y00002pDKxDQAW/ProfilePicture%202022-06-20%2019%3A57%3A24.788",biography:"Prof. Erick Sperandio is the Lead Researcher and professor of Artificial Intelligence (AI) at SENAI CIMATEC, Bahia, Brazil, also working with Computational Modeling (CM) and HPC. He holds a PhD in Environmental Engineering in the area of Atmospheric Computational Modeling, a Master in Informatics in the field of Computational Intelligence and Graduated in Computer Science from UFES. He currently coordinates, leads and participates in R&D projects in the areas of AI, computational modeling and supercomputing applied to different areas such as Oil and Gas, Health, Advanced Manufacturing, Renewable Energies and Atmospheric Sciences, advising undergraduate, master's and doctoral students. He is the Lead Researcher at SENAI CIMATEC's Reference Center on Artificial Intelligence. In addition, he is a Certified Instructor and University Ambassador of the NVIDIA Deep Learning Institute (DLI) in the areas of Deep Learning, Computer Vision, Natural Language Processing and Recommender Systems, and Principal Investigator of the NVIDIA/CIMATEC AI Joint Lab, the first in Latin America within the NVIDIA AI Technology Center (NVAITC) worldwide program. He also works as a researcher at the Supercomputing Center for Industrial Innovation (CS2i) and at the SENAI Institute of Innovation for Automation (ISI Automação), both from SENAI CIMATEC. He is a member and vice-coordinator of the Basic Board of Scientific-Technological Advice and Evaluation, in the area of Innovation, of the Foundation for Research Support of the State of Bahia (FAPESB). He serves as Technology Transfer Coordinator and one of the Principal Investigators at the National Applied Research Center in Artificial Intelligence (CPA-IA) of SENAI CIMATEC, focusing on Industry, being one of the six CPA-IA in Brazil approved by MCTI / FAPESP / CGI.br. He also participates as one of the representatives of Brazil in the BRICS Innovation Collaboration Working Group on HPC, ICT and AI. He is the coordinator of the Work Group of the Axis 5 - Workforce and Training - of the Brazilian Strategy for Artificial Intelligence (EBIA), and member of the MCTI/EMBRAPII AI Innovation Network Training Committee. He is the coordinator, by SENAI CIMATEC, of the Artificial Intelligence Reference Network of the State of Bahia (REDE BAH.IA). He leads the working group of experts representing Brazil in the Global Partnership on Artificial Intelligence (GPAI), on the theme \"AI and the Pandemic Response\".",institutionString:null,institution:null},{id:"241400",title:"Prof.",name:"Mohammed",middleName:null,surname:"Bsiss",slug:"mohammed-bsiss",fullName:"Mohammed Bsiss",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/241400/images/8062_n.jpg",biography:null,institutionString:null,institution:null},{id:"276128",title:"Dr.",name:"Hira",middleName:null,surname:"Fatima",slug:"hira-fatima",fullName:"Hira Fatima",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/276128/images/14420_n.jpg",biography:"Dr. Hira Fatima\nAssistant Professor\nDepartment of Mathematics\nInstitute of Applied Science\nMangalayatan University, Aligarh\nMobile: no : 8532041179\nhirafatima2014@gmal.com\n\nDr. Hira Fatima has received his Ph.D. degree in pure Mathematics from Aligarh Muslim University, Aligarh India. Currently working as an Assistant Professor in the Department of Mathematics, Institute of Applied Science, Mangalayatan University, Aligarh. She taught so many courses of Mathematics of UG and PG level. Her research Area of Expertise is Functional Analysis & Sequence Spaces. She has been working on Ideal Convergence of double sequence. She has published 17 research papers in National and International Journals including Cogent Mathematics, Filomat, Journal of Intelligent and Fuzzy Systems, Advances in Difference Equations, Journal of Mathematical Analysis, Journal of Mathematical & Computer Science etc. She has also reviewed few research papers for the and international journals. She is a member of Indian Mathematical Society.",institutionString:null,institution:null},{id:"417317",title:"Mrs.",name:"Chiedza",middleName:null,surname:"Elvina Mashiri",slug:"chiedza-elvina-mashiri",fullName:"Chiedza Elvina Mashiri",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Midlands State University",country:{name:"Zimbabwe"}}},{id:"352140",title:"Dr.",name:"Edina",middleName:null,surname:"Chandiwana",slug:"edina-chandiwana",fullName:"Edina Chandiwana",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Midlands State University",country:{name:"Zimbabwe"}}},{id:"342259",title:"B.Sc.",name:"Leonard",middleName:null,surname:"Mushunje",slug:"leonard-mushunje",fullName:"Leonard Mushunje",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Midlands State University",country:{name:"Zimbabwe"}}},{id:"347042",title:"Mr.",name:"Maxwell",middleName:null,surname:"Mashasha",slug:"maxwell-mashasha",fullName:"Maxwell Mashasha",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Midlands State University",country:{name:"Zimbabwe"}}},{id:"2941",title:"Dr.",name:"Alberto J.",middleName:"Jorge",surname:"Rosales-Silva",slug:"alberto-j.-rosales-silva",fullName:"Alberto J. Rosales-Silva",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Instituto Politécnico Nacional",country:{name:"Mexico"}}},{id:"437913",title:"Dr.",name:"Guillermo",middleName:null,surname:"Urriolagoitia-Sosa",slug:"guillermo-urriolagoitia-sosa",fullName:"Guillermo Urriolagoitia-Sosa",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Instituto Politécnico Nacional",country:{name:"Mexico"}}},{id:"435126",title:"Prof.",name:"Joaquim",middleName:null,surname:"José de Castro Ferreira",slug:"joaquim-jose-de-castro-ferreira",fullName:"Joaquim José de Castro Ferreira",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Aveiro",country:{name:"Portugal"}}},{id:"437899",title:"MSc.",name:"Miguel Angel",middleName:null,surname:"Ángel Castillo-Martínez",slug:"miguel-angel-angel-castillo-martinez",fullName:"Miguel Angel Ángel Castillo-Martínez",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Instituto Politécnico Nacional",country:{name:"Mexico"}}},{id:"289955",title:"Dr.",name:"Raja",middleName:null,surname:"Kishor Duggirala",slug:"raja-kishor-duggirala",fullName:"Raja Kishor Duggirala",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Jawaharlal Nehru Technological University, Hyderabad",country:{name:"India"}}}]}},subseries:{item:{id:"23",type:"subseries",title:"Computational Neuroscience",keywords:"Single-Neuron Modeling, Sensory Processing, Motor Control, Memory and Synaptic Pasticity, Attention, Identification, Categorization, Discrimination, Learning, Development, Axonal Patterning and Guidance, Neural Architecture, Behaviours and Dynamics of Networks, Cognition and the Neuroscientific Basis of Consciousness",scope:"Computational neuroscience focuses on biologically realistic abstractions and models validated and solved through computational simulations to understand principles for the development, structure, physiology, and ability of the nervous system. This topic is dedicated to biologically plausible descriptions and computational models - at various abstraction levels - of neurons and neural systems. This includes, but is not limited to: single-neuron modeling, sensory processing, motor control, memory, and synaptic plasticity, attention, identification, categorization, discrimination, learning, development, axonal patterning, guidance, neural architecture, behaviors, and dynamics of networks, cognition and the neuroscientific basis of consciousness. 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