Open access peer-reviewed Edited Volume

Updates on Brucellosis

Brucellosis is a major zoonotic disease that may cause a serious illness in humans and animals. Global prevalence of human brucellosis remains significant. More than half a million new brucellosis cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of these cases are reported in developing countries.In humans, brucellosis (undulant fever, Malta fever) is characterized by an acute bacteremic phase followed by a chronic stage that may extend over many years and may involve many tissues. It is a systemic disease, and many organ systems (nervous system, heart, skeletal system, bone marrow, etc.) may become involved following hematogenous dissemination. Although eradicated in some countries, it remains one of the most economically important zoonosis worldwide as it is responsible for huge economic losses as well as significant human morbidity in endemic areas. Because of the nonspecific clinical manifestations of human brucellosis and the need for prolonged combination therapy with antibiotics that are not routinely prescribed for other infectious diseases, laboratory confirmation of the diagnosis is of paramount importance for adequate patient management. In addition, evidence of brucellosis has serious public health implications because it discloses exposure to a contaminated source (infected animals or their products, unsafe laboratory practices, or a potential biological warfare attack). This book addresses human brucellosis with stress on symptoms including those related to the less recognized disease localizations, risk of exposure, treatment, and prevention. Light is shed on animal brucellosis as it pertains to human exposure. The book also emphasizes on laboratory procedures in culturing and serologic techniques. Epidemiologic surveillance is among this books subjects as well as veterinary control measures.

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Updates on BrucellosisEdited by Manal Mohammad Baddour

Published: November 19th 2015

DOI: 10.5772/59890

ISBN: 978-953-51-2211-1

eBook (PDF) ISBN: 978-953-51-7267-3

Copyright year: 2015

Books open for chapter submissions

17757 Total Chapter Downloads

17 Crossref Citations

13 Web of Science Citations

39 Dimensions Citations


Open access peer-reviewed

1. Risk Factors for Brucella spp. in Domestic and Wild Animals

By Ana Cláudia Coelho, Juan García Díez and Adosinda Maria Coelho


Open access peer-reviewed

2. Brucellosis at the Wildlife/Livestock/Human Interface

By Calvin Gomo


Open access peer-reviewed

3. The Interaction Between Brucella and the Host Cell in Phagocytosis

By Suk Kim


Open access peer-reviewed

4. Brucella-induced Thrombocytopenia and Bleeding

By Ali Akbar Heydari


Open access peer-reviewed

5. Ocular Manifestations of Brucellosis

By Ozlem Sahin


Open access peer-reviewed

6. Neurobrucellosis

By Farhad Abbasi and Soolmaz Korooni


Open access peer-reviewed

7. Brucellosis – Granulomatous Spine Infection

By Ana M. Cerván, Miguel Hirschfeld, Miguel Rodriguez and Enrique Guerado


Open access peer-reviewed

8. Blood Cultures for the Diagnosis of Human Brucellosis

By Pablo Yagupsky


Open access peer-reviewed

9. Antibiotic Susceptibility Testing of Brucella Species - Old and New Drugs

By Max Maurin


Open access peer-reviewed

10. Recombinant Proteins as Antigens in Serological Diagnosis of Brucellosis

By Magda Celina Navarro-Soto, Alberto Morales-Loredo, Genoveva Álvarez-Ojeda, Carlos Ramírez-Pfeiffer, Patricia Tamez-Guerra and Ricardo Gomez-Flores


Open access peer-reviewed

11. Treatment of Brucellosis

By Mitra Ranjbar


Open access peer-reviewed

12. Treatment of Human Brucellosis — Review of Evidence from Clinical Trials

By Julián Solís García del Pozo and Javier Solera


Open access peer-reviewed

13. Control of Animal Brucellosis — The Most Effective Tool to Prevent Human Brucellosis

By Marta Pérez-Sancho, Teresa García-Seco, Lucas Domínguez and Julio Álvarez


Edited Volume and chapters are indexed in

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