Open access peer-reviewed Edited Volume

Oxidative Stress

Molecular Mechanisms and Biological Effects

Edited by Volodymyr Lushchak

Vasyl Stefanyk Precarpathian National University, Ukraine


Halyna Semchyshyn

Vasyl Stefanyk Precarpathian National University, Ukraine

Since the discovery of free radicals in biological systems researchers have been highly interested in their interaction with biological molecules. Denoted in 1980, and due to fruitful results and ideas, oxidative stress is now appreciated by both basic and applied scientists as an enhanced steady state level of reactive oxygen species with wide range of biological effects. This book covers a wide range of aspects and issues related to the field of oxidative stress. The association between generation and elimination of reactive species and effects of oxidative stress are also addressed, as well as summaries of recent works on the signaling role of reactive species in eukaryotic organisms. The readers will gain an overview of our current understanding of homeostasis of reactive species and cellular processes they are involved in, as well as useful resources for further reading.

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Oxidative StressMolecular Mechanisms and Biological EffectsEdited by Volodymyr Lushchak

Published: April 25th 2012

DOI: 10.5772/2333

ISBN: 978-953-51-0554-1

eBook (PDF) ISBN: 978-953-51-5285-9

Copyright year: 2012

Books open for chapter submissions

47669 Total Chapter Downloads

23 Crossref Citations

63 Web of Science Citations

94 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter

By Volodymyr I. Lushchak and Halyna M. Semchyshyn


Open access peer-reviewed

2. Interplay Between Oxidative and Carbonyl Stresses: Molecular Mechanisms, Biological Effects and Therapeutic Strategies of Protection

By Halyna M. Semchyshyn and Volodymyr I. Lushchak


Open access peer-reviewed

3. Oxidative and Nitrosative Stresses: Their Role in Health and Disease in Man and Birds

By Hillar Klandorf and Knox Van Dyke


Open access peer-reviewed

4. Nitric Oxide Synthase and Oxidative Stress: Regulation of Nitric Oxide Synthase

By Ehab M. M. Ali, Soha M. Hamdy and Tarek M. Mohamed


Open access peer-reviewed

5. Iron, Oxidative Stress and Health

By Shobha Udipi, Padmini Ghugre and Chanda Gokhale


Open access peer-reviewed

6. Heme Proteins, Heme Oxygenase-1 and Oxidative Stress

By Hiroshi Morimatsu, Toru Takahashi, Hiroko Shimizu, Junya Matsumi, Junko Kosaka and Kiyoshi Morita


Open access peer-reviewed

7. Assessment of the General Oxidant Status of Individuals in Non-Invasive Samples

By Sandro Argüelles, Mercedes Cano, Mario F. Muñoz-Pinto, Rafael Ayala, Afrah Ismaiel and Antonio Ayala


Open access peer-reviewed

8. Hydrogen: From a Biologically Inert Gas to a Unique Antioxidant

By Shulin Liu, Xuejun Sun and Hengyi Tao


Open access peer-reviewed

9. Paraoxonase: A New Biochemical Marker of Oxidant-Antioxidant Status in Atherosclerosis

By Tünay Kontaş Aşkar and Olga Büyükleblebici


Open access peer-reviewed

10. Renal Redox Balance and Na+, K+-ATPase Regulation: Role in Physiology and Pathophysiology

By Elisabete Silva and Patrício Soares-da-Silva


Open access peer-reviewed

11. Effects of Oxidative Stress and Antenatal Corticosteroids on the Pulmonary Expression of Vascular Endothelial Growth Factor (VEGF) and Alveolarization

By Ana Remesal, Laura San Feliciano and Dolores Ludena


Open access peer-reviewed

12. Protection of Mouse Embryonic Stem Cells from Oxidative Stress by Methionine Sulfoxide Reductases

By Larry F. Lemanski, Chi Zhang, Andrei Kochegarov, Ashley Moses, William Lian, Jessica Meyer, Pingping Jia, Yuanyuan Jia, Yuejin Li, Keith A. Webster, Xupei Huang, Michael Hanna, Mohan P. Achary, Sharon L. Lemanski and Herbert Weissbach


Open access peer-reviewed

13. Structural and Activity Changes in Renal Betaine Aldehyde Dehydrogenase Caused by Oxidants

By Jesús A. Rosas-Rodríguez, Hilda F. Flores-Mendoza, Ciria G. Figueroa-Soto, Edgar F. Morán-Palacio and Elisa M. Valenzuela-Soto


Open access peer-reviewed

14. Signalling Oxidative Stress in Saccharomyces cerevisiae

By Maria Angeles de la Torre-Ruiz, Luis Serrano, Mima I. Petkova and Nuria Pujol-Carrion


Open access peer-reviewed

15. Role of the Yap Family in the Transcriptional Response to Oxidative Stress in Yeasts

By Christel Goudot, Frédéric Devaux and Gaëlle Lelandais


Open access peer-reviewed

16. The Yeast Genes ROX1, IXR1, SKY1 and Their Effect upon Enzymatic Activities Related to Oxidative Stress

By Ana García Leiro, Silvia Rodríguez Lombardero, Ángel Vizoso Vázquez, M. Isabel González Siso and M. Esperanza Cerdán


Open access peer-reviewed

17. Complex Regulatory Interplay Between Multidrug Resistance and Oxidative Stress Response in Yeast: The FLR1 Regulatory Network as a Systems Biology Case-Study

By Miguel C. Teixeira


Open access peer-reviewed

18. ROS as Signaling Molecules and Enzymes of Plant Response to Unfavorable Environmental Conditions

By Dominika Boguszewska and Barbara Zagdańska


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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