Open access peer-reviewed Edited Volume

Neurodegenerative Diseases

Molecular Mechanisms and Current Therapeutic Approaches

Edited by Nagehan Ersoy Tunalı

Istanbul Medeniyet University

Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical correlations, genetic aspects, neuropathological findings, and current therapeutic interventions in neurodegenerative diseases. I believe that this book will enlighten the curiosity for neurodegeneration and also encourage researchers to work on potentially effective molecular therapies for still mysterious neurodegenerative disorders.

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Neurodegenerative DiseasesMolecular Mechanisms and Current Therapeutic ApproachesEdited by Nagehan Ersoy Tunalı

Published: January 20th 2021

DOI: 10.5772/intechopen.83153

ISBN: 978-1-83880-150-2

Print ISBN: 978-1-83880-149-6

eBook (PDF) ISBN: 978-1-83880-360-5

Copyright year: 2021

Books open for chapter submissions

1436 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Cerebellum: Its Anatomy, Functions and Diseases

By Rajani Singh

182

Open access peer-reviewed

2. The Brain Stress System in the Neurobiology of the “Dark Side” of Addiction and Its Relation to Neurodegeneration

By Maria Uscinska, Nicolo’ Gagliano and Frank Ho-Yin Lai

111

Open access peer-reviewed

3. Biomarkers of Diseases: Their Role in Emergency Medicine

By Anoop T. Chakrapani

70

Open access peer-reviewed

4. Alzheimer’s Disease and Type 2 Diabetes Mellitus: Molecular Mechanisms and Similarities

By Karla Isabel Lira-De León, Alma Delia Bertadillo-Jilote, David Gustavo García-Gutiérrez and Marco Antonio Meraz-Ríos

124

Open access peer-reviewed

5. EEG Biomarker for Alzheimer’s Disease

By Demet Ilhan Algin, Demet Ozbabalık Adapinar and Oguz Osman Erdinc

96

Open access peer-reviewed

6. Multi-Target-Directed Ligands in Alzheimer’s Disease Therapy

By Eugenie Nepovimova and Kamil Kuca

108

Open access peer-reviewed

7. Molecular Mechanisms of Polyglutamine Pathology and Lessons Learned from Huntington’s Disease

By Nagehan Ersoy Tunalı

67

Open access peer-reviewed

8. Brain-Derived Neurotrophic Factor and Stem Cell-Based Technologies in Huntington’s Disease Therapy

By Irina Kerkis, Joyce Macedo da Silva, Cristiane Valverde Wenceslau, Nicole Caroline Mambelli-Lisboa and Eduardo Osorio Frare

255

Open access peer-reviewed

9. Amyotrophic Lateral Sclerosis

By Robin Warner

166

Open access peer-reviewed

10. Electrophysiological Investigations of Prion Protein Roles in Health and Disease

By Simote T. Foliaki, Bradley R. Groveman and Cathryn L. Haigh

159

Open access peer-reviewed

11. Molecular Mechanisms behind Initiation of Focal Seizure in Temporal Lobe Epilepsy: Computational Study

By Ruchi Jakhmola Mani and Deepshikha Pande Katare

104

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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