Open access peer-reviewed Edited Volume

Muscle Biopsy

Investigation of muscle diseases has changed dramatically with the understanding of genetic basis of a wide range of muscle diseases. Muscle biopsy has become a powerful tool not only to provide diagnosis but to make tissue available for genetic studies and to basic scientists for biomedical research. Accurate interpretation of muscle biopsy to detect cell dysfunction/ damage/death or absence / abnormality of a protein or genetic defect by the sophisticated technologies is important to guide treatment of various muscle diseases. In this book on muscle biopsy various chapters deal with the procedure and interpretation of muscle biopsy, its use in the culture of myotubes and membrane transport studies.Muscle biopsy is an important technique to investigate mitochondrial dysfunction and the mitochondrial DNA integrity in oxidation. Phosphorylation in various metabolic diseases like obesity, type 2 diabetes mellitus and peripheral vascular disease is explored in the other chapters with detailed descriptions on methodology. This book provides the advances in the basic techniques of muscle biopsy for a neuroscientist.

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Muscle BiopsyEdited by Challa Sundaram

Published: January 5th 2012

DOI: 10.5772/1241

ISBN: 978-953-307-778-9

Copyright year: 2012

Books open for chapter submissions

32124 Total Chapter Downloads

6 Crossref Citations

6 Web of Science Citations

12 Dimensions Citations

chaptersDownloads

Open access peer-reviewed

1. Percutaneous Muscle Biopsy: History, Methods and Acceptability

By Harnish P. Patel, Cyrus Cooper and Avan Aihie Sayer

6068

Open access peer-reviewed

2. Approach to the Interpretation of Muscle Biopsy

By C. Sundaram and Megha S. Uppin

13909

Open access peer-reviewed

3. Generation and Use of Cultured Human Primary Myotubes

By Lauren Cornall, Deanne Hryciw, Michael Mathai and Andrew McAinch

2688

Open access peer-reviewed

4. Membrane Transport in Human Skeletal Muscle

By Carsten Juel

1717

Open access peer-reviewed

5. Evaluation of Mitochondrial Functions and Dysfunctions in Muscle Biopsy Samples

By Frédéric Capel, Valentin Barquissau, Ruddy Richard and Béatrice Morio

3538

Open access peer-reviewed

6. Metabolic Exploration of Muscle Biopsy

By A.L. Charles, S. Dufour, T.N. Tran, J. Bouitbir, B. Geny and J. Zoll

2089

Open access peer-reviewed

7. Skeletal Muscle Mitochondrial Function in Peripheral Arterial Disease: Usefulness of Muscle Biopsy

By A. Lejay, A.L. Charles, J. Zoll, J. Bouitbir, F. Thaveau, F. Piquard and B. Geny

2115

Edited Volume and chapters are indexed in

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  • CNKI

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