Open access peer-reviewed Edited Volume

Muscle Biopsy

Investigation of muscle diseases has changed dramatically with the understanding of genetic basis of a wide range of muscle diseases. Muscle biopsy has become a powerful tool not only to provide diagnosis but to make tissue available for genetic studies and to basic scientists for biomedical research. Accurate interpretation of muscle biopsy to detect cell dysfunction/ damage/death or absence / abnormality of a protein or genetic defect by the sophisticated technologies is important to guide treatment of various muscle diseases. In this book on muscle biopsy various chapters deal with the procedure and interpretation of muscle biopsy, its use in the culture of myotubes and membrane transport studies.Muscle biopsy is an important technique to investigate mitochondrial dysfunction and the mitochondrial DNA integrity in oxidation. Phosphorylation in various metabolic diseases like obesity, type 2 diabetes mellitus and peripheral vascular disease is explored in the other chapters with detailed descriptions on methodology. This book provides the advances in the basic techniques of muscle biopsy for a neuroscientist.

Read more >Order hardcopy
Muscle BiopsyEdited by Challa Sundaram

Published: January 5th 2012

DOI: 10.5772/1241

ISBN: 978-953-307-778-9

eBook (PDF) ISBN: 978-953-51-6622-1

Copyright year: 2012

Books open for chapter submissions

36180 Total Chapter Downloads

10 Crossref Citations

14 Web of Science Citations

20 Dimensions Citations


Open access peer-reviewed

1. Percutaneous Muscle Biopsy: History, Methods and Acceptability

By Harnish P. Patel, Cyrus Cooper and Avan Aihie Sayer


Open access peer-reviewed

2. Approach to the Interpretation of Muscle Biopsy

By C. Sundaram and Megha S. Uppin


Open access peer-reviewed

3. Generation and Use of Cultured Human Primary Myotubes

By Lauren Cornall, Deanne Hryciw, Michael Mathai and Andrew McAinch


Open access peer-reviewed

4. Membrane Transport in Human Skeletal Muscle

By Carsten Juel


Open access peer-reviewed

5. Evaluation of Mitochondrial Functions and Dysfunctions in Muscle Biopsy Samples

By Frédéric Capel, Valentin Barquissau, Ruddy Richard and Béatrice Morio


Open access peer-reviewed

6. Metabolic Exploration of Muscle Biopsy

By A.L. Charles, S. Dufour, T.N. Tran, J. Bouitbir, B. Geny and J. Zoll


Open access peer-reviewed

7. Skeletal Muscle Mitochondrial Function in Peripheral Arterial Disease: Usefulness of Muscle Biopsy

By A. Lejay, A.L. Charles, J. Zoll, J. Bouitbir, F. Thaveau, F. Piquard and B. Geny


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£119

Order now

Residents of European Union countries need to add a Book Value-Added Tax Rate based on their country of residence. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase