Open access peer-reviewed Edited Volume

DNA Methylation Mechanism

Edited by Metin Budak

Trakya University


Mustafa Yildiz

Trakya University

‘Simplicity is the ultimate sophistication’- Leonardo Da Vinci
The methylation that occurs simply by attaching one or more methyl molecules to a DNA molecule continues to confuse the scientific world by creating highly complex molecular arrangements. Research on methylation mechanisms have discovered that this simple biochemical event (which adapts to the changing micro/macro environment of the organism, to diseases and even cancerous processes) has shown that it is actually not as simple as it seems. In the last 50 years, our efforts to understand these mechanisms and use them to benefit human beings have continued. With this book called “DNA methylation mechanism”, in which we try to explain the effects on every stage of life, we hope that we have been able to create a resource book for everyone interested in this field, from students who are interested, to amateurs and professionals.

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DNA Methylation MechanismEdited by Metin Budak

Published: July 1st 2020

DOI: 10.5772/intechopen.78125

ISBN: 978-1-83880-818-1

Print ISBN: 978-1-83880-817-4

eBook (PDF) ISBN: 978-1-83880-819-8

Copyright year: 2020

Books open for chapter submissions

3208 Total Chapter Downloads

2 Crossref Citations

1 Web of Science Citations

4 Dimensions Citations


Open access peer-reviewed

1. Radiation and DNA Methylation Mechanisms

By Metin Budak


Open access peer-reviewed

2. Demethylation in Early Embryonic Development and Memory

By Carol Bernstein and Harris Bernstein


Open access peer-reviewed

3. Global DNA Methylation as a Potential Underlying Mechanism of Congenital Disease Development

By Aleksandra Stanković


Open access peer-reviewed

4. Recent Insights into the Mechanisms of De Novo and Maintenance of DNA Methylation in Mammals

By Motoko Unoki


Open access peer-reviewed

5. DNA Hydroxymethylation in the Regulation of Gene Expression in Human Solid Cancer

By Sofia L. Alcaraz-Estrada, Gabriela Leija-Montoya, Nicolás Serafín-Higuera, Silvia García, Claudia E. Millán-Testa, Mónica Sierra-Martínez, Magali Blanco-Morales and Jorge Sandoval-Basilio


Open access peer-reviewed

6. Research Progress of DNA Methylation in Thyroid Cancer

By Zhu Gaohong and Xie Lijun


Open access peer-reviewed

7. Atlas of Age- and Tissue-Specific DNA Methylation during Early Development of Barley (Hordeum vulgare)

By Moumouni Konate, Mike J. Wilkinson, Benjamin T. Mayne, Eileen S. Scott, Bettina Berger and Carlos M. Rodríguez López


Open access peer-reviewed

8. Library Preparation for Whole Genome Bisulfite Sequencing of Plant Genomes

By Kendall R. Corbin and Carlos M. Rodriguez Lopez


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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