Open access peer-reviewed Edited Volume

Cells of the Immune System

Edited by Ota Fuchs

Institute of Hematology and Blood Transfusion


Seyyed Shamsadin Athari

Zanjan University of Medical Sciences

The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness.

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Cells of the Immune SystemEdited by Ota Fuchs

Published: May 13th 2020

DOI: 10.5772/intechopen.80249

ISBN: 978-1-78985-584-5

Print ISBN: 978-1-78985-583-8

eBook (PDF) ISBN: 978-1-83880-430-5

Copyright year: 2020

Books open for chapter submissions

4271 Total Chapter Downloads

3 Crossref Citations

1 Web of Science Citations

5 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter: Development of Neutrophils and Their Role in Hematopoietic Microenvironment Regulation

By Ota Fuchs


Open access peer-reviewed

2. Neutrophil Function Impairment Is a Host Susceptibility Factor to Bacterial Infection in Diabetes

By Daniella Insuela, Diego Coutinho, Marco Martins, Maximiliano Ferrero and Vinicius Carvalho


Open access peer-reviewed

3. Immune-Mediated Inflammation: Human T CD4 Helper Lymphocyte Diversity and Plasticity in Health and Disease

By Rodolfo Alberto Kölliker Frers, Matilde Otero-Losada, María Inés Herrera, Sabrina Porta, Vanesa Cosentino, Eduardo Kerzberg, Lucas Udovin and Francisco Capani


Open access peer-reviewed

4. Resident Memory T Cells

By Hasan Akbaba


Open access peer-reviewed

5. Modulating the T Lymphocyte Immune Response via Secretome Produced miRNA: From Tolerance Induction to the Enhancement of the Anticancer Response

By Mark D. Scott, Duncheng Wang, Wendy M. Toyofuku and Xining Yang


Open access peer-reviewed

6. Mucosal Macrophage Polarization Role in the Immune Modulation

By Tsung-Meng Wu, Shiu-Nan Chen and Yu-Sheng Wu


Open access peer-reviewed

7. KLF4-Mediated Plasticity of Myeloid-Derived Suppressor Cells (MDSCs)

By Daping Fan, Samir Raychoudhury and Walden Ai


Open access peer-reviewed

8. Eosinophilic Phenotype: The Lesson from Research Models to Severe Asthma

By Guida Giuseppe and Antonelli Andrea


Open access peer-reviewed

9. Eosinophilic Disorders: Extrinsic and Intrinsic Immune Response, New Diagnostic Perspectives, and Therapeutic Alternatives

By Maria-de-Lourdes Irigoyen-Coria, Vilma-Carolina Bekker-Mendez, Maria-Isabel Leyva-Carmona, Cecilia Rosel-Pech, Samuel Moreno-Olivares and David Solis-Hernandez


Open access peer-reviewed

10. Eosinophilic Cholangitis

By Gilles Jadd Hoilat, Judie Noemie Hoilat, Mohamad Fekredeen Ayas, Sana Riaz and Divey Manocha


Open access peer-reviewed

11. Eosinophilic Granulomatosis with Polyangiitis: The Beginning of a New Era

By Carlos Melero Moreno, Marta Corral Blanco and Rocío Magdalena Díaz Campos


Open access peer-reviewed

12. Assessment of Immune Reconstitution Following Hematopoietic Stem Cell Transplantation

By Meenakshi Singh, Selma Z. D’Silva and Abhishweta Saxena


Open access peer-reviewed

13. Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia

By Oksana O. Shevchuk, Elisaveta A. Snezhkova, Anatoliy G. Bilous, Veronika V. Sarnatskaya, Kvitoslava I. Badakhivska, Larysa A. Sakhno, Vasyl F. Chekhun and Volodymyr G. Nikolaev


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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