Open access peer-reviewed Edited Volume


An Update in Pathogenesis and Clinical Management

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide and is estimated to become the third most common cause of death over the next decade. The knowledge of COPD pathogenesis and the disease course has greatly improved this progression in understanding and continues to have significant implications in the management of this condition. Novel areas of interest in COPD pathogenesis include further development of animal models, a better understanding of the genetics and epigenetics, the role of the microbiome, and an increasing appreciation of the associated comorbidities. This book intends to provide the reader with a brief overview of these topics and also provide an in-depth review of the current nonpharmacological clinical approaches to managing patients with COPD.

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COPDAn Update in Pathogenesis and Clinical ManagementEdited by Cormac McCarthy

Published: February 21st 2018

DOI: 10.5772/intechopen.68194

ISBN: 978-953-51-3783-2

Print ISBN: 978-953-51-3782-5

eBook (PDF) ISBN: 978-953-51-4033-7

Copyright year: 2018

Books open for chapter submissions

9460 Total Chapter Downloads

4 Crossref Citations

4 Web of Science Citations

10 Dimensions Citations


Open access peer-reviewed

1. Animal Models of Chronic Obstructive Pulmonary Disease

By Lillian Chow, David Smith, Khushboo Chokshi, Wendy Ezegbunam, Prangthip Charoenpong, Kimberly Foley, Adrian Cargill and Patrick Geraghty


Open access peer-reviewed

2. Genetics Association and Epigenetic Changes in COPD

By Rajneesh Malhotra and Outi Vaarala


Open access peer-reviewed

3. The Respiratory Microbiome in COPD

By Orla O’Carroll, Joanna Peart, Eamon Mullen and Conor Burke


Open access peer-reviewed

4. Neurocognitive Impairment as Systemic Effects of COPD

By Cristian Oancea, Emanuela Tudorache and Voicu Tudorache


Open access peer-reviewed

5. Tobacco and Smoking Cessation

By Thomas Hering


Open access peer-reviewed

6. Pulmonary Rehabilitation in COPD: Current Practice and Future Directions

By Michelle Casey, Amy Mulkerns, Cliona O’Donnell and Tim McDonnell


Open access peer-reviewed

7. Advances in Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease and Associated Conditions

By Ipek Candemir


Edited Volume and chapters are indexed in

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