Open access peer-reviewed Edited Volume

Assessment of Cellular and Organ Function and Dysfunction using Direct and Derived MRI Methodologies

Edited by Christakis Constantinides

University of Oxford, United Kingdom

Despite the tremendous growth in the field of magnetic resonance imaging (MRI) evidenced in the initial phases of its development in the early twentieth century, scientific focus has shifted in recent years toward the study of physiology and pathophysiology that span the spatial scales of the molecule, cell, tissue, and organ. Intensified research activities over the past 15 years have justified efforts toward molecular and cellular imaging, dual-modality imaging systems, real-time acquisitions, dedicated image processing techniques and applications, and the critical evaluation of their potential translational value for use in the clinic. The integrative focus on molecular-cellular-tissue-organ function and dysfunction has taken a primary role in modern, personalized medicine, and it is envisaged to continue to do so, as accumulated knowledge from basic and clinical science work continues to elucidate molecular, cellular, and physiological/pathophysiological pathways and mechanisms. In this scientific effort, MRI continues to play a critical and synergistic role from the perspectives of basic science, diagnosis, and clinical interventional/therapeutic approaches. Within the realm of the current role of MRI in modern medicine, this book summarizes state-of-the-art direct and derived MRI methodologies and approaches as applied toward the assessment of cellular and organ function and dysfunction. The contributions in this effort are not excessive but few, comprehensive, and distinguished and of high quality. The topic areas can be generalized to find applications in other scientific areas and span both brain and cardiac applications, extending interest to wider audiences.

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Assessment of Cellular and Organ Function and Dysfunction using Direct and Derived MRI Met...Edited by Christakis Constantinides

Published: October 26th 2016

DOI: 10.5772/61953

ISBN: 978-953-51-2723-9

Print ISBN: 978-953-51-2722-2

eBook (PDF) ISBN: 978-953-51-7320-5

Copyright year: 2016

Books open for chapter submissions

7840 Total Chapter Downloads

22 Crossref Citations

27 Web of Science Citations

39 Dimensions Citations


Open access peer-reviewed

1. Introductory Chapter

By Christakis Constantinides


Open access peer-reviewed

2. Tracking Cellular Functions by Exploiting the Paramagnetic Properties of X‐Nuclei

By Eric Gottwald, Andreas Neubauer and Lothar R. Schad


Open access peer-reviewed

3. Novel Applications of Cardiovascular Magnetic Resonance Imaging-Based Computational Fluid Dynamics Modeling in Pediatric Cardiovascular and Congenital Heart Disease

By Margaret M. Samyn and John F. LaDisa


Open access peer-reviewed

4. Application of Spatial Bayesian Hierarchical Models to fMRI Data

By Kuo-Jung Lee


Open access peer-reviewed

5. Texture Analysis in Magnetic Resonance Imaging: Review and Considerations for Future Applications

By Andrés Larroza, Vicente Bodí and David Moratal


Edited Volume and chapters are indexed in

  • Worldcat
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  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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