Open access peer-reviewed Edited Volume

Modern Tools for Genetic Engineering

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Academic Editor

Michael Kormann

University of Tübingen, Germany

PublishedMay 18th, 2016

Doi10.5772/61377

ISBN978-953-51-2234-0

Print ISBN978-953-51-2392-7

eBook (PDF) ISBN978-953-51-5432-7

Copyright year2016

Number of pages226

Site-specific endonucleases create double-strand breaks within the genome and can be targeted to literally any genetic mutation. Together with a repair template, a correction of the defective locus becomes possible. This book offers insight into the modern tools of genome editing, their hurdles and their huge potential. A new era of in vivo genetic engineering has begun.

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Table of Contents

Open access  chapters

2,692
1
2. Gene Delivery Technologies for Efficient Genome Editing: Applications in Gene Therapy

By Francisco Martin, Sabina Sánchez-Hernández, Alejandra Gutierrez- Guerrero and Karim Benabdellah

2,031
3. DNA Elements Tetris: A Strategy for Gene Correction

By Colette Bastie and Florence Rouleux-Bonnin

1,670
1,621
5. Gene Editing in Adult Hematopoietic Stem Cells

By Sergio López-Manzaneda, Sara Fañanas-Baquero, Virginia Nieto- Romero, Francisco-Jose Roman-Rodríguez, Maria Fernandez-Garcia, Maria J. Pino-Barrio, Fatima Rodriguez-Fornes, Begoña Diez- Cabezas, Maria Garcia-Bravo, Susana Navarro, Oscar Quintana- Bustamante and Jose C. Segovia

2,103
1
2,404
2,244
2

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16,467 Total Chapter Downloads

4 Crossref Citations

5 Web of Science Citations

7 Dimensions Citations

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