Open access peer-reviewed Edited Volume

New Insights into Toxicity and Drug Testing

Edited by Sivakumar Joghi Thatha Gowder

Qassim University, Saudi Arabia

This book "New Insights into Toxicity and Drug Testing" covers all emerging technologies (profiling technologies, 3D cultures, next generation sequencing etc.), available methods and models to evaluate candidate drugs and medicinal plants with reference to toxicity, drug testing and development. This book is an original contribution of experts from different parts of the globe and the in-depth information will be a significant resource for scientists and physicians who are directly dealing with drugs / medicines and human life.

Read more >Order hardcopy
New Insights into Toxicity and Drug TestingEdited by Sivakumar Joghi Thatha Gowder

Published: January 23rd 2013

DOI: 10.5772/55886

ISBN: 978-953-51-0946-4

eBook (PDF) ISBN: 978-953-51-7068-6

Copyright year: 2013

Books open for chapter submissions

38626 Total Chapter Downloads

87 Crossref Citations

120 Web of Science Citations

212 Dimensions Citations


Open access peer-reviewed

1. Pre-Clinical Assessment of the Potential Intrinsic Hepatotoxicity of Candidate Drugs

By Jacob John van Tonder, Vanessa Steenkamp and Mary Gulumian


Open access peer-reviewed

2. The Kidney Vero-E6 Cell Line: A Suitable Model to Study the Toxicity of Microcystins

By Carina Menezes, Elisabete Valério and Elsa Dias


Open access peer-reviewed

3. Why are Early Life Stages of Aquatic Organisms more Sensitive to Toxicants than Adults?

By Azad Mohammed


Open access peer-reviewed

4. Screening of Herbal Medicines for Potential Toxicities

By Obidike Ifeoma and Salawu Oluwakanyinsola


Open access peer-reviewed

5. Retracted: New Trends in Genotoxicity Testing of Herbal Medicinal Plants

By Hala M. Abdelmigid


Open access peer-reviewed

6. Animal Models in Drug Development

By Ray Greek


Open access peer-reviewed

7. Renal Transporters and Biomarkers in Safety Assessment

By P.D. Ward, D. La and J.E. McDuffie


Open access peer-reviewed

8. Autophagy: A Possible Defense Mechanism in Parkinson's Disease?

By Rosa A. González-Polo, Rubén Gómez-Sánchez, Lydia Sánchez- Erviti, José M Bravo-San Pedro, Elisa Pizarro-Estrella, Mireia Niso- Santano and José M. Fuentes


Open access peer-reviewed

9. Physiologically Based Pharmacokinetic Modeling: A Tool for Understanding ADMET Properties and Extrapolating to Human

By Micaela B. Reddy, Harvey J. Clewell III, Thierry Lave and Melvin E. Andersen


Open access peer-reviewed

10. Plasma Methadone Level Monitoring in Methadone Maintenance Therapy: A Personalised Methadone Therapy

By Nasir Mohamad, Roslanuddin Mohd Salehuddin, Basyirah Ghazali, Nor Hidayah Abu Bakar, Nurfadhlina Musa, Muslih Abdulkarim Ibrahim, Liyana Hazwani Mohd Adnan, Ahmad Rashidi and Rusli Ismail


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

Order a hardcopy of the Edited Volume

Free shipping with DHL Express

Hardcover (ex. VAT)£119

Order now

Residents of European Union countries need to add a Book Value-Added Tax Rate based on their country of residence. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

Special discount for IntechOpen contributors

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Login and purchase