Open access peer-reviewed Edited Volume

Autoimmune Diseases

Contributing Factors, Specific Cases of Autoimmune Diseases, and Stem Cell and Other Therapies

Edited by James Chan

Monash University, Australia

Autoimmune disease represents a group of more than 60 different chronic autoimmune diseases that affect approximately 6% of the population. Autoimmune diseases arise when ones immune system actively targets and destroys self tissue resulting in clinical disease with prime examples such as Lupus and Type 1 diabetes. The immune system is designed to protect us from foreign pathogens such as viruses and bacteria. However, during the process of generating immune cells for this purpose, as a negative consequence, self-reactive immune cells are also generated. This book aims to present the latest knowledge and insights regarding the different contributing factors and their interplay, discussions on several autoimmune diseases and their case studies, and therapeutic treatments, including stem cell, for autoimmune diseases.

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Autoimmune DiseasesContributing Factors, Specific Cases of Autoimmune Diseases, and Stem Cell and Other TherapiesEdited by James Chan

Published: July 25th 2012

DOI: 10.5772/2896

ISBN: 978-953-51-0693-7

eBook (PDF) ISBN: 978-953-51-7020-4

Copyright year: 2012

Books open for chapter submissions

32655 Total Chapter Downloads

7 Crossref Citations

6 Web of Science Citations

17 Dimensions Citations


Open access peer-reviewed

1. Current Theories for Multiple Sclerosis Pathogenesis and Treatment

By Marcus Muller, Rachael Terry, Stephen D. Miller and Daniel R. Getts


Open access peer-reviewed

2. Immunologic and Genetic Factors in Type 1 Diabetes Mellitus

By Ahmad Massoud and Amir Hossein Massoud


Open access peer-reviewed

3. Balancing pro- and anti-inflammatory CD4+ T helper cells in the intestine

By Nicola Gagliani and Samuel Huber


Open access peer-reviewed

4. T cell metabolism in autoimmune diseases

By Dan Li, Miranda Piccioni, Zhimei Gao, Chen Chen, Zuojia Chen, Jia Nie, Zhao Shan, Yangyang Li, Andy Tsun and Bin Li


Open access peer-reviewed

5. Apoptosis and Autoimmune Disorders

By Reginald Halaby


Open access peer-reviewed

6. Immune Complex Deposits as a Characteristic Feature of Mercury-Induced SLE-Like Autoimmune Process in Inbred and Outbred Mice

By Alla Arefieva, Marina Krasilshchikova and Olga Zatsepina


Open access peer-reviewed

7. Celiac And Inflammatory Bowel Diseases In Children With Primary Humoral Immunodeficiency

By Pituch-Noworolska and Katarzyna Zwonarz


Open access peer-reviewed

8. Central Nervous System Resident Cells in Neuroinflammation: A Brave New World.

By J.P.S. Peron, D. Oliveira, W. N. Brandão, A. Fickinger, A. P. Ligeiro de Oliveira, L. V. Rizzo and N.O.S. Câmara


Open access peer-reviewed

9. Autoimmune Encephalitis in Rural Central Illinois

By Reuben Mari Valenzuela, Paayal Patel and Jorge C. Kattah


Open access peer-reviewed

10. The Role of the Antigen GAD 65 in Diabetes Mellitus Type 1: A Molecular Analysis

By Marco Wiltgen and Gernot Tilz


Open access peer-reviewed

11. New Therapeutic Challenges in Autoimmune Diseases

By Eun Wha Choi


Open access peer-reviewed

12. Stem Cell Therapies for Type I Diabetes

By Jesus Ciriza and Jennifer Manilay


Open access peer-reviewed

13. Stem Cell-Based Cellular Therapy in Rheumatoid Arthritis

By Rizwanul Haque, Fengyang Lei, Xiaofang Xiong and Jianxun Song


Open access peer-reviewed

14. Biologic Treatment in Rheumatoid Arthritis

By Katerina Chatzidionysiou


Open access peer-reviewed

15. Biologic Therapy in Patients with Juvenile Idiopathic Arthritis – A Unique Single Centre Experience at the Scientific-Research Pediatric Centre in the Russian Federation

By A.A. Baranov, E.I. Alexeeva, L.S. Namazova-Baranova, T.M. Bzarova, S.I. Valiyeva, R.V. Denisova, K.B. Isayeva, A.M. Chomakhidze, E.G. Chistyakova, T.V. Sleptsova, E.V. Mitenko, E.I. Zelikovich, G.V. Kurilenko, E.L. Semikina, A.V. Anikin, A.M. Stepanchenko, N.I. Taybulatov, A.V. Starikova, I.V. Dvoryakovskiy and M.V. Ryazanov


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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