Open access peer-reviewed Edited Volume


The history of pharmacology travels together to history of scientific method and the latest frontiers of pharmacology open a new world in the search of drugs. New technologies and continuing progress in the field of pharmacology has also changed radically the way of designing a new drug. In fact, modern drug discovery is based on deep knowledge of the disease and of both cellular and molecular mechanisms involved in its development. The purpose of this book was to give a new idea from the beginning of the pharmacology, starting from pharmacodynamic and reaching the new field of pharmacogenetic and ethnopharmacology.

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PharmacologyEdited by Luca Gallelli

Published: March 14th 2012

DOI: 10.5772/2218

ISBN: 978-953-51-0222-9

eBook (PDF) ISBN: 978-953-51-6870-6

Copyright year: 2012

Books open for chapter submissions

111017 Total Chapter Downloads

21 Crossref Citations

86 Web of Science Citations

82 Dimensions Citations


Open access peer-reviewed

1. Metabotropic Receptors for Glutamate and GABA

By Gregory Stewart, Julie Kniazeff, Laurent Prézeau, Philippe Rondard, Jean-Philippe Pin and Cyril Goudet


Open access peer-reviewed

2. Interactions Between Glutamate Receptors and TRPV1 Involved in Nociceptive Processing at Peripheral Endings of Primary Afferent Fibers

By You-Hong Jin, Motohide Takemura, Akira Furuyama and Norifumi Yonehara


Open access peer-reviewed

3. Molecular Pharmacology of Nucleoside and Nucleotide HIV-1 Reverse Transcriptase Inhibitors

By Brian D. Herman and Nicolas Sluis-Cremer


Open access peer-reviewed

4. Opioid Kappa Receptor Selective Agonist TRK-820 (Nalfurafine Hydrochloride)

By Hideaki Fujii, Shigeto Hirayama and Hiroshi Nagase


Open access peer-reviewed

5. The Cannabinoid 1 Receptor and Progenitor Cells in the Adult Central Nervous System

By Alexandra Sideris, Thomas Blanck and Esperanza Recio-Pinto


Open access peer-reviewed

6. Peroxisome Proliferator Activated Receptor Alpha (PPAR) Agonists: A Potential Tool for a Healthy Aging Brain

By Jennifer Tremblay-Mercier


Open access peer-reviewed

7. The Influence of Cyclophosphamide on Immune Function of Murine Macrophages

By Krzysztof Bryniarski


Open access peer-reviewed

8. Modification of Interleukin-10 with Mannose-6-Phosphate Groups Yields a Liver-Specific Cytokine with Antifibrotic Activity in Rats

By Heni Rachmawati, Adriana Mattos, Catharina Reker-Smit, Klaas Poelstra and Leonie Beljaars


Open access peer-reviewed

9. Pharmacogenetics: The Scientific Basis

By Bosun Banjoko


Open access peer-reviewed

10. Future of Pharmacogenetics in Cardiovascular Diseases

By Rianne M.F. Van Schie, Talitha I. Verhoef, Anke-Hilse Maitland-Van Der Zee, Anthonius de Boer, Tom Schalekamp, Felix J.M. Van Der Meer, William K. Redekop and Rahber Thariani


Open access peer-reviewed

11. Warfarin Enantiomers Pharmacokinetics by CYP2C19

By Yumiko Akamine and Tsukasa Uno


Open access peer-reviewed

12. Pharmacogenetics - A Treatment Strategy for Alcoholism

By Anjana Munshi and Vandana Sharma


Open access peer-reviewed

13. Pharmacological Approaches to Improve Ageing

By Pedro J. Camello, Cristina Camello-Almaraz and Maria J. Pozo


Open access peer-reviewed

14. Pharmacological Neuromodulation in Autism Spectrum Disorders

By Bill J. Duke


Open access peer-reviewed

15. Pharmacology of Hormone Replacement Therapy in Menopause

By Adela Voican, Bruno Francou, Liliana Novac, Nathalie Chabbert-Buffet, Marianne Canonico, Geri Meduri, Marc Lombes, Pierre-Yves Scarabin, Jacques Young, Anne Guiochon-Mantel and Jérôme Bouligand


Open access peer-reviewed

16. A Multi-Level Analysis of World Scientific Output in Pharmacology

By Carlos Olmeda-Gómez, Ma-Antonia Ovalle-Perandones and Antonio Perianes-Rodríguez


Open access peer-reviewed

17. Mephedrone-Related Fatalities in the United Kingdom: Contextual, Clinical and Practical Issues

By John M. Corkery, Fabrizio Schifano and A. Hamid Ghodse


Open access peer-reviewed

18. Novel Strategies in Drug-Induced Acute Kidney Injury

By Alberto Lázaro, Sonia Camaño, Blanca Humanes and Alberto Tejedor


Open access peer-reviewed

19. Chemical and Physical Enhancers for Transdermal Drug Delivery

By José Juan Escobar-Chávez, Isabel Marlen Rodríguez-Cruz and Clara Luisa Domínguez-Delgado


Open access peer-reviewed

20. Application of Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry

By Nobuhiro Zaima


Open access peer-reviewed

21. Closed-Loop Control of Anaesthetic Effect

By Santiago Torres, Juan A. Méndez, Héctor Reboso, José A. Reboso and Ana León


Open access peer-reviewed

22. The Influence of Displacement by Human Groups Among Regions in the Medicinal Use of Natural Resource: A Case Study in Diadema, São Paulo - Brazil

By Daniel Garcia and Lin Chau Ming


Open access peer-reviewed

23. Unconventional Raw Natural Sustainable Sources for Obtaining Pharmacological Principles Potentially Active on CNS Through Catalytic, Ecologically Clean, Processes

By Yanier Nuñez Figueredo, Juan E. Tacoronte Morales, Alicia Lagarto Parra, Olinka Tiomno Tiomnova, Jorge Tobella Sabater and Jorge Leyva Simeon


Open access peer-reviewed

24. Elucidating the Role of Biliverdin Reductase in the Expression of Heme Oxygenase-1 as a Cytoprotective Response to Stress

By James R. Reed


Open access peer-reviewed

25. Antibothropic Action of Camellia sinensis Extract Against the Neuromuscular Blockade by Bothrops jararacussu Snake Venom and Its Main Toxin, Bothropstoxin-I

By Yoko Oshima-Franco, Luana de Jesus Reis Rosa, Gleidy Ana Araujo Silva, Jorge Amaral Filho, Magali Glauzer Silva, Patricia Santos Lopes, José Carlos Cogo, Adélia Cristina Oliveira Cintra and Maria Alice da Cruz-Höfling


Open access peer-reviewed

26. The Effects of Viscum album (Mistletoe) QuFrF Extract and Vincristine in Human Multiple Myeloma Cell Lines - A Comparative Experimental Study Using Several and Different Parameters

By Eva Kovacs


Open access peer-reviewed

27. Ethanol Toxicity in the Brain: Alteration of Astroglial Cell Function

By Metoda Lipnik-Štangelj


Open access peer-reviewed

28. The Involvement of Purinergic System in Pain: Adenosine Receptors and Inosine as Pharmacological Tools in Future Treatments

By Francisney Pinto Nascimento, Sérgio José Macedo Jr. and Adair Roberto Soares Santos


Open access peer-reviewed

29. Therapeutic Organometallic Compounds

By Beril Anilanmert


Open access peer-reviewed

30. Aging: Drugs to Eliminate Methylglyoxal, a Reactive Glucose Metabolite, and Advanced Glycation Endproducts

By Indu Dhar and Kaushik Desai


Open access peer-reviewed

31. Ethanol Interference on Adenosine System

By Silvânia Vasconcelos, Sarah Escudeiro, Ana Luíza Martin, Paula Soares, Antônio Vieira Filho, Larissa Silva, Kátia Cilene Dias, Danielle Macêdo, Francisca Cléa Sousa and Marta Fonteles


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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