Open access peer-reviewed Edited Volume

Advances in Hepatology

Edited by Luis Rodrigo

University of Oviedo


Ian James Martins

Independent Scientist

Xiaozhong Guo

General Hospital of Northern Theater Command

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Xingshun Qi

General Hospital of Northern Theater Command

This book discusses clinical advances in hepatology, with a focus on metabolic diseases and chronic hepatitis C. The development of direct-acting antiviral (DAA) agents for the treatment of hepatitis C virus (HCV) infection in 2010 has completely transformed the management of this disease. This transformative nature of DAA therapy underpins the goal of the World Health Organization (WHO) to eliminate HCV infection as a public health threat by 2030. The advantages of using these therapies include high efficacy (sustained virological response rate >95%) with minimal side effects, good tolerability, easy drug administration (once-daily oral dosing) and short duration of treatment (8-12 weeks). The commercialization of second-generation DAA agents due to their high effectiveness, few side-effects and pangenotypic action. This transformative nature of DAA therapy underpins the goal of the WHO to eliminate HCV infection as a public health threat by 2030.

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Advances in HepatologyEdited by Luis Rodrigo

Published: July 28th 2021

ISBN: 978-1-83968-624-5

Print ISBN: 978-1-83968-623-8

eBook (PDF) ISBN: 978-1-83968-625-2

Copyright year: 2021

Books open for chapter submissions

1471 Total Chapter Downloads


Open access peer-reviewed

1. Discovery of Hepatitis C Virus: Nobel Prize in Physiology and Medicine 2020

By Talari Praveen


Open access peer-reviewed

2. Hepatitis C: An Overview

By Syed Manzoor Kadri and Marija Petkovic


Open access peer-reviewed

3. Extrahepatic Manifestations of Hepatitis C Infection

By Alberto Frosi


Open access peer-reviewed

4. Host-Targeting Antivirals for Treatment of Hepatitis C

By Bouchra Kitab, Michinori Kohara and Kyoko Tsukiyama-Kohara


Open access peer-reviewed

5. The Influence of Protease Inhibitors on the Evolution of Hepatitis C in Patients with HIV and HCV Co-Infection

By Elena Dumea and Simona Claudia Cambrea


Open access peer-reviewed

6. Liver Transplantation and HCV Genotype 4

By Saad Alghamdi and Waleed Al-hamoudi


Open access peer-reviewed

7. Hepatocellular Carcinoma and Antiviral Therapies in HCV Chronic Infection

By Laura Iliescu


Open access peer-reviewed

8. Diagnosis of Nonalcoholic Steatohepatitis

By Eira Cerda-Reyes, Alicia Sarahi Ojeda-Yuren, Julián Torres-Vazquez, María del Rosario Herrero Maceda, Martín Uriel Vázquez-Medina, Perla Denice Flores-Rangel, Yailin Fabiola Velásquez Palacios, Saraid Cerda-Reyes and Graciela Elia Castro-Narro


Open access peer-reviewed

9. Treatment of Nonalcoholic Fatty Liver Disease through Changes in Gut Microbiome and Intestinal Epithelial Barrier

By Hassan M. Heshmati


Open access peer-reviewed

10. The Role of Bariatric Surgery in Fatty Liver

By Anja Geerts and Sander Lefere


Open access peer-reviewed

11. Spontaneous Bacterial Peritonitis: Physiopathological Mechanism and Clinical Manifestations

By Rebeca Pérez-Cabeza De Vaca, Balasubramaniyan Vairappan, Tomás Cortés Espinoza, Juan Antonio Suárez Cuenca, Cuauhtemoc Licona Cassani, Brenda Maldonado Arriaga, Chrisitan Navarro Gerrard, Diana Selene Morgan Penagos, Paul Mondragón Terán and Victoria Chagoya De Sanchez


Open access peer-reviewed

12. Hepatorenal Syndrome

By Arshpal Gill, Ra’ed Nassar, Ruby Sangha, Mohammed Abureesh, Dhineshreddy Gurala, Zeeshan Zia, Rachelle Hamadi and Suzanne El-Sayegh


Open access peer-reviewed

13. Treatment Approach in Patients with Decompensated Liver Cirrhosis

By Anıl Delik and Yakup Ülger


Open access peer-reviewed

14. Therapy that Targets Growth Factor Receptors: Novel Approach for Liver Cirrhosis Treatment

By Halyna Kuznietsova and Olexandr Ogloblya


Edited Volume and chapters are indexed in

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  • AZ ebsco
  • Base
  • CNKI

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