About the book
Histoplasmosis is an infection caused by a fungus called Histoplasma. Two main varieties affect humans, Histoplasma capsulatum and Histoplasma duboisii. Histoplasma duboisii is geographically restricted to the African continent (African Histoplasmosis). Histoplasmosis has emerged as an important opportunistic infection in patients with advanced HIV disease. Histoplasmosis is more common than tuberculosis in some regions of the world imposing unique clinical and public health challenges.
Over the years, we have seen an improvement and advances in the diagnosis and management approaches to histoplasmosis. Histoplasma antigen has been included on the World Health Organisation list of essential diagnostics. Essential antifungal agents including fluconazole, Itraconazole, voriconazole and amphotericin B are now on the WHO list of Essential Medicines. Several stakeholders including WHO, GAFFI, and others have targeted histoplasmosis as a priority disease requiring a multi-sectoral approach. This book intends to provide a comprehensive yet concise state-of-the knowledge on histoplasmosis aimed at improving the understanding of this disease and improvement in patient care.