About the book
Mass spectrometry is one of the most sensitive and most precise analytical techniques for the detection and analysis of both organic and inorganic molecules. Mass spectrometry is currently used for analysis and characterization of proteins and their modifications in proteomic and clinical studies, for detection and characterization of therapeutic antibodies and monitoring the level of active substances in patients' blood.
Mass spectrometry has a significant potential to further advance the clinical analysis and be a diagnostic tool for pathology or being used in the operation room and enable fast detection of tumor's margin.
This book aims to provide an insight into different application fields of mass spectrometry for clinical research and routine. Modern mass spectrometry enables analysis and quantitation of very complex samples such as serum or tissue proteome or lipidome and the mass spectrometry imaging complements tissue analysis in pathology departments.
Furthermore, mass spectrometry can be used in an operating room as a device for on-site detection of tumor margins and be a valuable help for the surgeon.
Mass spectrometry imaging of tissue is an advanced type of tissue analysis that complements and aids the pathology and the traditional tissue analysis by staining and optical microscopy.