Open access peer-reviewed Edited Volume

Tandem Mass Spectrometry

Applications and Principles

Tandem Mass Spectrometry - Applications and Principles presents comprehensive coverage of theory, instrumentation and major applications of tandem mass spectrometry. The areas covered range from the analysis of drug metabolites, proteins and complex lipids to clinical diagnosis. This book serves multiple groups of audiences; professional (academic and industry), graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences.

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Tandem Mass SpectrometryApplications and PrinciplesEdited by Jeevan Prasain

Published: February 29th 2012

DOI: 10.5772/1327

ISBN: 978-953-51-0141-3

eBook (PDF) ISBN: 978-953-51-4342-0

Copyright year: 2012

Books open for chapter submissions

233170 Total Chapter Downloads

49 Crossref Citations

149 Web of Science Citations

162 Dimensions Citations


Open access peer-reviewed

1. Applications of Tandem Mass Spectrometry: From Structural Analysis to Fundamental Studies

By Paulo J. Amorim Madeira and M. Helena Florêncio


Open access peer-reviewed

2. Tandem Mass Spectrometry of Peptides

By Renata Soares, Elisabete Pires, André M. Almeida, Romana Santos, Ricardo Gomes, Kamila Koči, Catarina Ferraz Franco and Ana Varela Coelho


Open access peer-reviewed

3. Evolutionary Proteomics: Empowering Tandem Mass Spectrometry and Bioinformatics Tools for the Study of Evolution

By Irving E. Vega, Dan Rittschof, Gary H. Dickinson and Ian Musgrave


Open access peer-reviewed

4. Proteomic Strategies for Comprehensive Identification of Post-Translational Modifications of Cellular Proteins Including Low Abundant and Novel Modifications

By Jaeho Jeong, Jae-Jin Lee and Kong-Joo Lee


Open access peer-reviewed

5. Tandem Mass Spectrometry and Glycoproteins

By Pavlina Dolashka


Open access peer-reviewed

6. Proteomics Methodology Applied to the Analysis of Filamentous Fungi - New Trends for an Impressive Diverse Group of Organisms

By Carlos Barreiro, Carlos García-Estrada and Juan F. Martín


Open access peer-reviewed

7. ETD and ECD Mass Spectrometry Fragmentation for the Characterization of Protein Post Translational Modifications

By Lisa Elviri


Open access peer-reviewed

8. Tandem Mass Spectrometry for Simultaneous Qualitative and Quantitative Analysis of Protein

By Lay-Harn Gam


Open access peer-reviewed

9. Comparative Proteomics of Tandem Mass Spectrometry Analyses for Bacterial Strains Identification and Differentiation

By Rabih E. Jabbour, Mary M. Wade, Samir V. Deshpande, Michael F. Stanford, Alan W. Zulich and A. Peter Snyder


Open access peer-reviewed

10. The Use of Mass Spectrometry for Characterization of Fungal Secretomes

By Eduardo Callegari and Mario Navarrete


Open access peer-reviewed

11. Strategies and Challenges in Measuring Protein Abundance Using Stable Isotope Labeling and Tandem Mass Spectrometry

By Kolbrun Kristjansdottir, Satoe Takahashi, Samuel L. Volchenboum and Stephen J. Kron


Open access peer-reviewed

12. The Use of Mass Spectrometry in Characterization of Bone Morphogenetic Proteins from Biological Samples

By Genadij Razdorov and Slobodan Vukicevic


Open access peer-reviewed

13. Tandem Mass Spectrometry of Tagged and Permethylated Polysaccharides

By Wen-Bin Yang


Open access peer-reviewed

14. Metabolomics Research with Tandem Mass Spectrometry

By Guo-Fang Zhang, Qingling Li, Ling Li and Takhar Kasumov


Open access peer-reviewed

15. Determination of Ractopamine Residues in Pigs by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry

By Jelka Pleadin, Ana Vulić, Nina Perši and Wolfgang Radeck


Open access peer-reviewed

16. Simultaneous LC-MS/MS Determination of Racemic Warfarin and Etravirine in Rat Plasma and Its Application in Pharmacokinetic Studies

By Jyothy John, Keila Robinson, Mathew John, Jason Caballero, Jing Ma, Dong Liang and Cyril Abobo


Open access peer-reviewed

17. Application of Tandem Mass Spectrometry for Analyzing Melamine

By Wei-Chih Cheng and I-Jen Wang


Open access peer-reviewed

18. Identifying and Overcoming Matrix Effects in Drug Discovery and Development

By Terence G. Hall, Inese Smukste, Karen R. Bresciano, Yunxia Wang, David McKearn and Ronald E. Savage


Open access peer-reviewed

19. Evaluating PK/PD Relationship of CNS Drug by Using Liquid Chromtography/ Tandem Mass Spectrometry Coupled to In Vivo Microdialysis

By Ying Qu, Loren Olson, Xiaohui Jiang, Leah Aluisio, Christopher King, Elliott B. Jones and Timothy W. Lovenberg


Open access peer-reviewed

20. Principles and Applications of LC-MS/MS for the Quantitative Bioanalysis of Analytes in Various Biological Samples

By Ju-Seop Kang


Open access peer-reviewed

21. HPLC-MS/MS of Highly Polar Compounds

By Luigi Silvestro, Isabela Tarcomnicu and Simona Rizea Savu


Open access peer-reviewed

22. Quantification of Glucuronide Metabolites in Biological Matrices by LC-MS/MS

By Jurij Trontelj


Open access peer-reviewed

23. Tandem Mass Spectrometry of Alkanolamines in Environmental Samples

By John Headley, Kerry Peru, Adeola Adenugba and Dena McMartin


Open access peer-reviewed

24. Application of Tandem Mass Spectrometry in Chemical Kinetics

By Jinping Qiao


Open access peer-reviewed

25. Electrospray Ionization Tandem Mass Spectrometry as a Tool for the Structural Elucidation and Dereplication of Natural Products: An Overview

By Herbert Júnior Dias, Nathalya Isabel de Melo and Antônio Eduardo Miller Crotti


Open access peer-reviewed

26. From the Collisionally Induced Dissociation to the Enzyme-Mediated Reactions: The Electron Flux Within the Lignan Furanic Ring

By Andreina Ricci and Simona Piccolella


Open access peer-reviewed

27. Characterization of Phospholipid Molecular Species by Means of HPLC-Tandem Mass Spectrometry

By Natale G. Frega, Deborah Pacetti and Emanuele Boselli


Open access peer-reviewed

28. Clinical Applications

By Joseph Herman and Bori Shushan


Open access peer-reviewed

29. Tandem Mass Spectrometry of Sphingolipids: Application in Metabolic Studies and Diagnosis of Inherited Disorders of Sphingolipid Metabolism

By Ladislav Kuchař, Befekadu Asfaw and Jana Ledvinová


Open access peer-reviewed

30. Newborn Screening By Tandem Mass Spectrometry: Impacts, Implications and Perspectives

By François Rousseau, Yves Giguère, Marie-Thérèse Berthier, Dominique Guérette, Jean-Guy Girard and Michel Déry


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI
  • BKCI

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