Open access peer-reviewed Edited Volume

Assisted Reproductive Technologies - Current Practices and New Perspectives

Iavor K. Vladimirov

Sofia IVF clinic

Dr. Vladimirov is the founder and medical director of the Sofia IVF Clinic. He is also one of the authors of the book "Theory about the Embryo Cryo-Treatment", the first theory that provides a scientific explanation for the high success rate in the use of frozen embryos. Dr. Vladimirov introduces for the first time in Bulgaria the methods for Ovarian Reserve Assessment, In Vitro Maturation method,Determination of “implantation window” in the endometrium, using Endometrial Receptivity Analysis (ERA) test.


Ovarian Reserve Indication of ART Treatment Stimulation Protocols Monitoring of Ovarian Stimulation Oocytes and Sperm Preparation Manipulation Techniques Surrogacy Cross Border IVF Treatment Preimplantation Genetic Testing Endometrial Receptivity Ethical aspects of ART Ovarian Rejuvenation

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About the book

This book is intended for professionals dealing with diagnostics and treatment of infertility and aims to provide comprehensive information on the current state of assisted reproductive technologies and their directions of development.
Assisted Reproductive Technologies (ART) is a key technology for treating infertility, which occurs in 10-15% of the general population in reproductive age. This has been one of the most tumultuously developing interdisciplinary technologies in medicine in recent decades. Thanks to in vitro methods, more than 5 million children were born in the whole world. For 40 years, the success rates of this treatment have increased many times, respectively in the first years from less than 10% to more than 50% in present days (in some groups of patients). The reason for this rapid increase is the introduction of new drugs and stimulation protocols, improvement of embryo culture media, and the use of new types of laboratory equipment that improve the conditions for embryo development. Last but not least, the introduction of modern genetic methods, as well as new gamete and tissue freezing techniques, has improved the methods' diagnostic and therapeutic capabilities.

Publishing process

Book initiated and editor appointed

Date completed: March 24th 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: June 7th 2022

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: August 6th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: October 25th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: December 24th 2022

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About the editor

Iavor K. Vladimirov

Sofia IVF clinic

Dr. Iavor K. Vladimirov graduated in Medicine at the Sofia Medical University in 1990. In 1997 he became an Obstetrics and Gynaecology specialist. In 2003, he wrote a doctoral thesis on 'Diagnostic Testing to Assess the Ovarian Reserve of Infertile Women”, and obtained a Ph.D. Dr. Vladimirov was, in the period between 2008 and 2010, a secretary of the Bulgarian Association of Sterility and Reproductive Health. He hаѕ оvеr 25 уеаrѕ’ of ехреrіеnсе іn the аѕѕіѕtеd rерrоduсtіоn and іntrоduсеd the method of 'іn vіtrо mаturаtіоn” tо Вulgаrіа. Dr. Iavor Vladimirov іѕ thе fіrѕt Вulgаrіаn rерrоduсtіvе mеdісіnе ѕресіаlіѕt whо wоn оnе оf thе mоѕt рrеѕtіgіоuѕ аwаrd оf 'Тhе Society for Reproductive Endocrinology and Infertility” оf Тhе Аmеrісаn Ѕосіеtу fоr Rерrоduсtіvе Меdісіnе (АЅRМ) fоr уеаr 2016 and won the prestigious \'Daniela Seizova - In the Name of Life\' award in the category \'Physician of 2016.\' Since 2004 he is the Medical Director of the IVF unit in SBALAGRM – Sofia, Bulgaria. Since 2008 he is a Lector of the Faculty of Biology, Sofia University 'St. Kliment Ohridski”, Sofia, Bulgaria.

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