Open access peer-reviewed Edited Volume

Atopic Dermatitis

Celso Pereira

Coimbra University


Skin Barrier Dysfunction Allergens Mechanisms Histamine Emollients Allergen Avoidance Corticosteroids Calcineurin Inhibitors Biological Agents Immunosuppressants Agents Antimicrobial Agents Phenotypes

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About the book

Atopic dermatitis is one of the most frequent skin disorders, particularly in pediatric ages. The enormous heterogeneity of mechanisms, triggers, clinical severity patterns, and treatment strategies have allowed a huge set of data from recent research that will allow more personalized management of the disease. Several clinical phenotypes were identified and engaged on precise pathogenic mechanisms whereby different cells and mediators are critical representing current discussion hot topics. An example is non-histaminergic pruritus with enormous difficulties in the clinic and with obvious implications on patient’s daily quality of life. Since skin barrier dysfunction is a very important aspect in the pathogenesis, the new investigations with emollient and humectants agents are very promising because they will allow more careful prescriptions directed to different clinical patterns. In addition to the standard pharmacological therapeutic, new topical or systemic agents, anti-inflammatory, immunomodulatory or biological agents, are now undergoing clinical trials with very promising results, despite the inexistent of clinical robust biomarkers. Similarly, in clinical phenotypes with outbreaks of recurrent skin infection by bacteria or fungi, future investigations with agents capable of destroying biofilms may have excellent benefit in the patient’s management. This book project will aim to frame the most current phytopathogenic evidence in atopic dermatitis and the scientific rationale of the currently available therapeutic arsenal and the new options that are projected particularly for severe forms of the disease.

Publishing process

Book initiated and editor appointed

Date completed: June 16th 2020

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

Approved chapters written in full and submitted

Deadline for full chapters: September 5th 2020

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: November 24th 2020

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: January 23rd 2021

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About the editor

Celso Pereira

Coimbra University

Prof Celso Pereira is currently responsible for Clinic Immunology, Medicine Faculty of Coimbra University and graduated specialist in Immuno-allergy at Coimbra’s Universitary Hospital Centre, at Coimbra, Portugal. He is also the past president of the Immunoallergy Board of the Portuguese Medical Association. His main activities include clinical practice, education (pre and post graduate) and clinical and laboratorial research. He is member of national committee for vaccination. His scientific interests include the participation and development of several research projects, but now have focused his interest in the mechanisms of allergy and specific immunotherape has edited two scientific books, and has more than 90 scientific publications including book chapters, and scientific papers. He published over 300 abstracts related to the research projects developed and presented at scientific events. He was also honored with 31 scientific awards. He was responsible for the first subcutaneous application of latex immunotherapy and for the first long term sublingual native Pru p3 desensitization. During his Iberian Chapter Presidency of the Latin-American Allergy, Asthma and Immunology Society he coordinated an international multicentre study focusing aeroallergen sensitization in the Iberian Peninsula. He is an associate editor of 4 scientific Journals related to Allergy and Clinical Immunology. He has been participating in the organization of scientific meetings and actively collaborates with the scientific committees of diverse Medical Scientific Societies.

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Book chapters authored 3

Books edited 4

Introducing your Author Service Manager

Ms. Sandra Maljavac

As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact.

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