Dr Pablo Oppezzo received his MSc in Molecular and Cellular Biology from PEDECIBA (Uruguay) in 1999. In 2004, he received his PhD in Immunology from the University Paris VI, and did post-doctoral work at the Biochemical Structural Unit at the Pasteur Institute of Paris. In 2006 he obtained a position as Principal Investigator of Recombinant Protein Unit at Institut Pasteur de Montevideo, Uruguay. Dr Pablo Oppezzo is now the Head of the Recombinant Protein Unit and Professor in the Immunology department at the School of Medicine, Republic University (UdelaR), Uruguay. Dr Oppezzo’s research focuses on the mechanisms involved in the origins of haematopoietic B-cell malignancies, specifically the study of the mutagenic action of the enzyme Activation-Induced cytidine deaminase. In the last years, he contributed to elucidate the mechanism of somatic hypermutation and class switch recombination process in Chronic Lymphocytic Leukemia and to identify new prognosis markers for this disease.