Liang Wang

Southern Medical University

Prof. Liang Wang is a group leader and principal investigator at Guangdong Provincial People\'s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, China. He also works as a research fellow at the University of Queensland and the University of Western Australia. He is an adjunct professor at the School of Medical and Health Sciences, Edith Cowan University, Australia. His current research interests are computational and experimental bacteriology, focusing on bacterial evolution, metabolism, and rapid diagnosis. Prof. Wang serves as an associate editor for Frontiers in Microbiology and is an editorial board member of BMC Microbiology, PeerJ, and Translational Metabolic Syndrome Research. To date, Prof. Wang has published more than 100 peer-reviewed papers in international journals.

Liang Wang

1books edited

2chapters authored

Latest work with IntechOpen by Liang Wang

Bacterial biofilm is a complex structure with diverse bacterial cells in a highly organized and ordered group within a matrix of extracellular polymeric substances they produce. Microbes attach to surfaces to develop biofilms, a sophisticated process regulated by factors such as nutritional status and biotic/abiotic surface features. An established biofilm structure mainly comprises bacterial cells, proteins, nucleic acid, and exo-polysaccharides that are extracellular macromolecules excreted as tightly bound layers in microbes, providing a perfect niche for bacteria to exchange genetic material between cells. In addition, bacterial cells in the matrix also communicate via quorum sensing, which greatly impacts biofilm processes. Under clinical circumstances, bacterial biofilm shows great resistance to antibiotics, disinfectants, and body defense systems, making it difficult for clinicians to eradicate and facilitate many infectious disease processes, leading to chronic infections of patients with long-term hospitalization and high mortality rates. Therefore, it is very important to understand the recent advances in forming, regulating, and eradicating biofilms in human infections to better prevent, control, and treat biofilm infections in humans. Written by an international team of basic and clinical researchers, the chapters of this book provide novel insights and advanced knowledge for life science researchers, clinical researchers, doctors, and other interested readers on some of the latest developments in biofilms.

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