Oytun Erbaş

ERBAS Institute of Experimental Medicine

Prof. Oytun Erbaş is an expert in physiology and experimental medicine. His main field of experience is pharmaceutical R&D studies, neuroscience, biological psychology, and pathophysiology. He currently works in the Department of Pathophysiology at various universities. He is the founder of Experimental Medicine R&D labs in Illinois, USA, and Istanbul-Türkiye. For his experimental work, he received the 2013 Politzer Prize from the International Society of Otologic Surgery in the field of otolaryngology and the 2013 Jacques Duparc Award from the European Society of Orthopedics and Traumatology. His research interests include inflammation and psychiatric relationships, oxytocin effects, mechanisms and treatment of epilepsy, neurodevelopmental disorders (autism) and treatment, and neuroprotective drug trials in neuropathy.

Oytun Erbaş

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Latest work with IntechOpen by Oytun Erbaş

As a member of the protein family known as neurotrophins, brain-derived neurotrophic factor (BDNF) plays a crucial role in supporting healthy brain function, which includes synaptic plasticity, cellular differentiation, learning, and the survival of nerve cells. Neuronal plasticity refers to the nervous system’s ability to adapt and respond to environmental conditions, involving various structural and functional mechanisms that can lead to changes in neural circuits, the formation of new synapses, and the generation of fresh neurons. BDNF has emerged as a significant regulator of neuronal plasticity. It is worth noting that the pathophysiological processes underlying central nervous system disorders and neuropsychiatric conditions such as depression, anxiety, autism, and schizophrenia, as well as neurodegenerative diseases like Parkinson’s and Alzheimer’s, are influenced by BDNF. Due to its robust neuroprotective properties and recently discovered anti-inflammatory and anti-apoptotic characteristics, BDNF has long been considered a potential candidate for preventing neurodegeneration. In the context of autism spectrum disorder, BDNF holds great promise as a central focus for therapeutic efforts. Its significance extends to the field of spinal cord injury, where it assumes a multifaceted role in the intricate pathophysiological processes at play. BDNF functions as a catalyst for the growth of axons, a crucial step in the restoration of the nervous system following damage. In the context of sepsis, research into the potential of BDNF’s anti-inflammatory properties to mitigate organ damage is quite noteworthy. Additionally, current findings suggest that combining exercise with vitamin D may offer a promising approach to increase BDNF levels and improve brain health. This book presents comprehensive information on BDNF and its role in promoting neuroprotection. The chapters offer insights into recent developments, molecular principles, and innovative therapeutic approaches for neurodegenerative disorders and brain health.

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