Jia-Ping Wu

By Sergey Suchkov, Tahereh Seifi Salmi, Chyi-Huey Bai, Javad Alizargar and Jia-Ping Wu

Sarcopenic obesity is a skeletal muscle weight loss disease. It has happened at an elderly age. A ketogenic diet is a low-carbohydrate (5%), moderate protein (15%), and a higher-fat diet (80%) can help sarcopenic obese patients burn their fat more effectively. It has many benefits for muscle and fat weight loss. A ketogenic diet can be especially useful for losing excess body fat without hunger and for improving type 2 diabetes. That is because of only a few carbohydrates in the diet, the liver converts fat into fatty acids and ketones. Ketone bodies can replace higher ATP energy. This diet forces the human body to burn fat. This is a good way to lose fat weight without restriction.

Part of the book: Role of Obesity in Human Health and Disease

By Jia-Ping Wu

The ketogenic diet and walking exercise training interventions are two key public health lifestyle factors. The potential of combined lifestyle factors interventions focused on getting to compliance in diet and exercise. A balanced ketogenic diet and regular exercise interventions is key modifiable factor to the prevention and management of community older frailty and skeletal muscle sarcopenia. Influence health across the lifespan and reduction of the risk of premature death through several biochemistry mechanisms. Community older group’s lifestyle factors interventions contribute identity in their natural living environment. While the older health benefits of walking exercise training interventions strategies are commonly to study, combining ketogenic diet and walking exercise interventions can induce greater benefits in community older groups.

Part of the book: Frailty and Sarcopenia

By Jia-Ping Wu, Zhu Xiaoning, Li Xiaoqing, Zhang Jie and Zhang Qian-Cheng

Aging changes in the very elderly cardiac disease are associated with physiological and pathological changes, however, all observed changes in aging are associated with a deterioration of cardiorespiratory fitness function. For example, hypertension and cardiorespiratory disease make difficult distinctions between normal aging changes and the effects of underlying resveratrol supplements processes. Cardiorespiratory fitness-independent changes in resveratrol intake are still unclear. This review aimed to discuss whether the aging-associated cardiorespiratory fitness changes in the heart can be reversed by resveratrol supplements, and the mechanisms of cardiorespiratory fitness. Aging led to apoptosis and fibrosis-related protein expression increased, however, cardiorespiratory fitness had revered more functions. Resveratrol supplements in combination with cardiorespiratory fitness had a good enhanced mitochondrial function in aging including IL-6, STAT3, MEK5, and MEK1/ERK1 increased. Resveratrol supplements also induced survival signals and downregulation of apoptosis signaling in aging. Therefore, we suggest resveratrol has enhanced cardiorespiratory fitness to combine their function in repressed aging.

Part of the book: Resveratrol - Recent Advances, Application, and Therapeutic Potential [Working title]