Ali Gholamrezanezhad

Johns Hopkins UniversityUnited States of America

Dr. Ali Gholamrezanezhad is a fellow of the European Board on Nuclear Medicine (FEBNM), with research experiences at Johns Hopkins University and University Klinikum Bonn (Germany). He is also a Senior Investigator (Research Institute for Nuclear Medicine, Tehran University of Medical Sciences), Editorial Board Member of Rare Tumors, Anatolian Journal of Cardiology, Journal of Thoracic Disease, Eastern Journal of Medicine and Reviewer of Clinical Neurology and Neurosurgery, Iranian Journal of Nuclear Medicine, Anatolian Journal of Cardiology, Plasma Chemistry and Plasma Processing, etc. Dr. Gholamrezanezhad has published 84 peer reviewed papers with experiences on stem cell imaging, such as: In vivo tracking of 111In-Oxine labeled mesenchymal stem cells following infusion in Patients with advanced cirrhosis. Nuclear Medicine and Biology. Letter to the Editor: Emerging Approaches for Cardiovascular Stem Cell Imaging. Current Cardiovascular Imaging Reports. Cytotoxicity of 111In-Oxine on Mesenchymal Stem Cells: A Time Dependent Adverse Effect. Nuclear Medicine Communications. Is there any benefit in generating thyrocyte from stem cell? Polish Journal of Endocrinology. The first experience of stem cell labeling in Iran using 111In-Oxine. Iranian J Nucl Med.

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Latest work with IntechOpen by Ali Gholamrezanezhad

Based on our current understanding of cell biology and strong supporting evidence from previous experiences, different types of human stem cell populations are capable of undergoing differentiation or trans-differentiation into functionally and biologically active cells for use in therapeutic purposes. So far, progress regarding the use of both in vitro and in vivo regenerative medicine models already offers hope for the application of different types of stem cells as a powerful new therapeutic option to treat different diseases that were previously considered to be untreatable. Remarkable achievements in cell biology resulting in the isolation and characterization of various stem cells and progenitor cells has increased the expectation for the development of a new approach to the treatment of genetic and developmental human diseases. Due to the fact that currently stem cells and umbilical cord banks are so strictly defined and available, it seems that this mission is investigationally more practical than in the past. On the other hand, studies performed on stem cells, targeting their conversion into functionally mature tissue, are not necessarily seeking to result in the clinical application of the differentiated cells; In fact, still one of the important goals of these studies is to get acquainted with the natural process of development of mature cells from their immature progenitors during the embryonic period onwards, which can produce valuable results as knowledge of the developmental processes during embryogenesis. For example, the cellular and molecular mechanisms leading to mature and adult cells developmental abnormalities are relatively unknown. This lack of understanding stems from the lack of a good model system to study cell development and differentiation. Hence, the knowledge reached through these studies can prove to be a breakthrough in preventing developmental disorders. Meanwhile, many researchers conduct these studies to understand the molecular and cellular basis of cancer development. The fact that cancer is one of the leading causes of death throughout the world, highlights the importance of these researches in the fields of biology and medicine.

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