The main difference in clinical presentation in patients with DLS and ADIS [24].
\\n\\n
\\n"}]',published:!0,mainMedia:{caption:"Milestone",originalUrl:"/media/original/124"}},components:[{type:"htmlEditorComponent",content:'
Barely three months into the new year and we are happy to announce a monumental milestone reached - 150 million downloads.
\n\nThis achievement solidifies IntechOpen’s place as a pioneer in Open Access publishing and the home to some of the most relevant scientific research available through Open Access.
\n\nWe are so proud to have worked with so many bright minds throughout the years who have helped us spread knowledge through the power of Open Access and we look forward to continuing to support some of the greatest thinkers of our day.
\n\nThank you for making IntechOpen your place of learning, sharing, and discovery, and here’s to 150 million more!
\n\n\n\n\n'}],latestNews:[{slug:"intechopen-supports-asapbio-s-new-initiative-publish-your-reviews-20220729",title:"IntechOpen Supports ASAPbio’s New Initiative Publish Your Reviews"},{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"}]},book:{item:{type:"book",id:"7499",leadTitle:null,fullTitle:"Kinetics of Enzymatic Synthesis",title:"Kinetics of Enzymatic Synthesis",subtitle:null,reviewType:"peer-reviewed",abstract:'Kinetics of Enzymatic Synthesis gives insight into different aspects of chemical reactions that are catalyzed by enzymes. This book is divided into two sections: "Enzyme Kinetics" and "Enzymatic Synthesis". The first section consists of two chapters with a halophilic enzyme kinetics and thermodynamic approach towards analyzing the influence of co-solvents on the Michaelis constants of enzyme-catalyzed reactions. The second section consists of three chapters. Production of isoamyl acetate using the enzymatic synthesis method between acetic anhydride and isoamyl alcohol by having enzyme Candida antarctica Lipase B as catalyst in a solvent-free system is discussed in the third chapter. The integrated scheme with the use of the filtrate from the pretreatment of the CS and the growth conditions of Pleurotus cystidiosus is studied in the fourth chapter. The last chapter of this section provides the conditions of the key parameters in microfluidic systems (residence times, flow rates, concentrations) applied for a sequential process from liquid/liquid extraction of LVV-h7.',isbn:"978-1-78985-030-7",printIsbn:"978-1-78985-029-1",pdfIsbn:"978-1-83881-830-2",doi:"10.5772/intechopen.76270",price:119,priceEur:129,priceUsd:155,slug:"kinetics-of-enzymatic-synthesis",numberOfPages:122,isOpenForSubmission:!1,isInWos:null,isInBkci:!1,hash:"ec806ce44e877d1bd8d3dcbf1fbc2f3f",bookSignature:"Lakshmanan Rajendran and Carlos Fernandez",publishedDate:"January 30th 2019",coverURL:"https://cdn.intechopen.com/books/images_new/7499.jpg",numberOfDownloads:5137,numberOfWosCitations:7,numberOfCrossrefCitations:4,numberOfCrossrefCitationsByBook:0,numberOfDimensionsCitations:7,numberOfDimensionsCitationsByBook:0,hasAltmetrics:0,numberOfTotalCitations:18,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"March 21st 2018",dateEndSecondStepPublish:"May 8th 2018",dateEndThirdStepPublish:"July 7th 2018",dateEndFourthStepPublish:"September 25th 2018",dateEndFifthStepPublish:"November 24th 2018",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"35190",title:"Prof.",name:"Lakshmanan",middleName:null,surname:"Rajendran",slug:"lakshmanan-rajendran",fullName:"Lakshmanan Rajendran",profilePictureURL:"https://mts.intechopen.com/storage/users/35190/images/system/35190.png",biography:"Dr. L. Rajendran is a Professor at the Department of Mathematics, Academy of Maritime Education and Training (Deemed to be University),Chennai , India. He has published 100(National) and 105(International/SCI) publications. He serves as a reviewer in many International Journals. He completed 6 research projects from various funding agencies in India. More than 35 students completed the Ph.D under his guidance.",institutionString:"Academy of Maritime Education and Training",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"2",totalChapterViews:"0",totalEditedBooks:"1",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:{id:"207726",title:"Dr.",name:"Carlos",middleName:null,surname:"Fernandez",slug:"carlos-fernandez",fullName:"Carlos Fernandez",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:"Dr. Carlos Fernandez is a lecturer in analytical chemistry at Robert Gordon University. He has published over 50 peer-reviewed articles. His research interests focus on the use of voltammetric techniques in analytical chemistry as an electrochemical sensor to detect the following analytes: heavy metals for environmental applications, drugs of abuse, amino acids, and pharmaceutical drugs with and without graphene-based compounds. Furthermore, his research emphasizes the utilization of graphene-based compounds and nanocomposites for energy storage devices. He is also interested in the investigation of corrosion processes using electrochemical techniques.",institutionString:"Robert Gordon University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"Robert Gordon University",institutionURL:null,country:{name:"United Kingdom"}}},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"50",title:"Enzymology",slug:"biochemistry-genetics-and-molecular-biology-enzymology"}],chapters:[{id:"63618",title:"Kinetics of Halophilic Enzymes",doi:"10.5772/intechopen.81100",slug:"kinetics-of-halophilic-enzymes",totalDownloads:1389,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Hypersaline environments are those with salt concentrations 9–10 times higher (30–35% of NaCl) than sea water (3.5% of NaCl). At high concentrations of soluble salts, cytoplasm—mainly of bacteria and archaea—is exposed to high ionic strength and achieves osmotic equilibrium by maintaining a cytoplasmic salt concentration similar to that of the surrounding media. Halophilic enzymes are extremozymes produced by halophilic microorganisms; they have similar characteristics to regular enzymes but different properties, mainly structural. Among these properties is a high requirement of salt for biological functions. Furthermore, the discovery of enzymes capable of degrading biopolymers offer a new perspective in the treatment of residues from oil deposits, under typically high conditions of salt and temperature, while giving valuable information on heterotrophic processes in saline environments.",signatures:"Luis Alberto Cira-Chávez, Joseph Guevara-Luna, Marisela Yadira\nSoto-Padilla, Brenda Román-Ponce, María Soledad Vásquez-\nMurrieta and María Isabel Estrada-Alvarado",downloadPdfUrl:"/chapter/pdf-download/63618",previewPdfUrl:"/chapter/pdf-preview/63618",authors:[{id:"128805",title:"Dr.",name:"Luis Alberto",surname:"Cira Chávez",slug:"luis-alberto-cira-chavez",fullName:"Luis Alberto Cira Chávez"},{id:"186307",title:"Dr.",name:"María",surname:"Vásquez-Murrieta",slug:"maria-vasquez-murrieta",fullName:"María Vásquez-Murrieta"},{id:"258387",title:"Dr.",name:"Maria Isabel",surname:"Estrada",slug:"maria-isabel-estrada",fullName:"Maria Isabel Estrada"},{id:"270818",title:"MSc.",name:"Joseph",surname:"Guevara Luna",slug:"joseph-guevara-luna",fullName:"Joseph Guevara Luna"},{id:"270819",title:"Dr.",name:"Marisela Yadira",surname:"Soto Padilla",slug:"marisela-yadira-soto-padilla",fullName:"Marisela Yadira Soto Padilla"},{id:"270820",title:"Dr.",name:"Brenda",surname:"Román Ponce",slug:"brenda-roman-ponce",fullName:"Brenda Román Ponce"}],corrections:null},{id:"63433",title:"Thermodynamic Activity-Based Michaelis Constants",doi:"10.5772/intechopen.80235",slug:"thermodynamic-activity-based-michaelis-constants",totalDownloads:988,totalCrossrefCites:2,totalDimensionsCites:5,hasAltmetrics:0,abstract:"The classical approach towards analysing the influence of co-solvents (i.e., cellular molecules that are chemically inert and do not act as reacting agents) on the Michaelis constants of enzyme-catalysed reactions is empirical. More precisely, reaction kinetics is usually mathematically modelled by fitting empirical parameters to experimental concentration vs. time data. In this chapter, a thermodynamic approach is presented that replaces substrate concentrations by thermodynamic activities of the substrates. This approach allows determining activity-based Michaelis constants. The advantage of such activity-based constants \n\n\nK\nM\na\n\n\n over their concentration-based pendants \n\n\nK\nM\nobs\n\n\n is twofold: First, \n\n\nK\nM\na\n\n\n is independent of any co-solvent added (while \n\n\nK\nM\nobs\n\n\n is not) as long as it does not directly interfere with the reaction mechanism (e.g., inhibitor or activator). Second, known \n\n\nK\nM\na\n\n\n values allow predictions of Michalis constants for different enzymes and reactions under co-solvent influence. This is demonstrated for a pseudo-one-substrate peptide hydrolysis reaction as well as for more complex two-substrate alcohol dehydrogenase reactions.",signatures:"Anton Wangler, Mark Jonathan Bunse, Gabriele Sadowski and\nChristoph Held",downloadPdfUrl:"/chapter/pdf-download/63433",previewPdfUrl:"/chapter/pdf-preview/63433",authors:[{id:"251514",title:"Dr.",name:"Christoph",surname:"Held",slug:"christoph-held",fullName:"Christoph Held"},{id:"265768",title:"Prof.",name:"Gabriele",surname:"Sadowski",slug:"gabriele-sadowski",fullName:"Gabriele Sadowski"},{id:"265769",title:"MSc.",name:"Anton",surname:"Wangler",slug:"anton-wangler",fullName:"Anton Wangler"},{id:"265771",title:"M.Sc.",name:"Mark",surname:"Bunse",slug:"mark-bunse",fullName:"Mark Bunse"}],corrections:null},{id:"64450",title:"Solvent-Free Isoamyl Acetate Production via Enzymatic Esterification",doi:"10.5772/intechopen.81333",slug:"solvent-free-isoamyl-acetate-production-via-enzymatic-esterification",totalDownloads:1011,totalCrossrefCites:1,totalDimensionsCites:1,hasAltmetrics:0,abstract:"Isoamyl acetate is an organic compound which is mainly used as flavor additive in food industries. Traditionally, the food flavor has been produced by extraction from plants, followed by chemical synthesis route which then shifted to biocatalytic route due to consumer’s awareness and inclination toward natural products. This study was carried out to examine the reaction synthesis between acetic anhydride and isoamyl alcohol in the presence of Candida antarctica Lipase-B (CALB) as a catalyst in solvent-free system (SFS). Results show that two reactions took place between acetic anhydride and isoamyl alcohol. The effect of different reaction parameters on the final yield of isoamyl acetate and the optimization of process parameters using a statistical tool were also investigated with response surface methodology (RSM). It was found that the optimum isoamyl acetate yield is at reaction temperature 30°C, acid/alcohol molar ratio 0.10, and enzyme loading 4.14%. The regression coefficient for optimization based on RSM was 0.9961. Errors resulted from model validation is less than 1% and is acceptable for real-life application. RSM model and first principle model were selected to determine the reaction kinetics and yield of reaction for isoamyl acetate. The results showed that RSM model provides a good predication of the esterification system with R2 value of 0.90.",signatures:"Nurhazwani Yusoff Azudin and Syamsul Rizal Abd Shukor",downloadPdfUrl:"/chapter/pdf-download/64450",previewPdfUrl:"/chapter/pdf-preview/64450",authors:[{id:"238365",title:"Associate Prof.",name:"Syamsul Rizal",surname:"Abd Shukor",slug:"syamsul-rizal-abd-shukor",fullName:"Syamsul Rizal Abd Shukor"},{id:"260210",title:"Mrs.",name:"Nurhazwani",surname:"Yusoff Azudin",slug:"nurhazwani-yusoff-azudin",fullName:"Nurhazwani Yusoff Azudin"}],corrections:null},{id:"63010",title:"Obtaining Enzymatic Extract from Pleurotus spp. Associated with an Integrated Process for Conversion of Lignocellulosic Biomass to Bioproducts",doi:"10.5772/intechopen.79848",slug:"obtaining-enzymatic-extract-from-pleurotus-spp-associated-with-an-integrated-process-for-conversion-",totalDownloads:892,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"The pretreatment of biomass has been integrated with enzyme production through the recycling of aqueous fractions. A process integrated with Pleurotus cystidiosus was grown, and enzymatic hydrolysis was realized. Samples of every liquid fraction from the fungal growing medium were analyzed to determine the chemical oxygen demand (OCD), glucose (Glu), xylose (Xyl), and total reducing sugars (RS). Separately, to obtain valuable polymers from this integration process, solid hemicellulose and lignin were isolated from the remaining liquid fractions through pH variation. The composition of the samples was determined using scanning electron microscopy (SEM), optical stereoscopic microscopy, and Fourier transform infrared (FTIR) spectroscopy and was compared with commercial homologs. The maximum conversion of cellulose to glucose by the obtained liquid fraction of the fungal medium was 61.3 ± 0.9% of the theoretical conversion yield of the commercial enzyme. Similarly, the conversion of hemicelluloses to xylose was 69.5 ± 1.5%. Finally, in this work, an integrated platform for cellulose, hemicellulose, lignin, enzymatic extract, and sugars production, which also significantly reduces water consumption, was proposed.",signatures:"Alma Hortensia Serafin-Muñoz, Carlos Eduardo Molina-Guerrero,\nBerenice Noriega Luna, Julio César Leal Vaca and Aurelio Alvarez-\nVargas",downloadPdfUrl:"/chapter/pdf-download/63010",previewPdfUrl:"/chapter/pdf-preview/63010",authors:[{id:"246331",title:"Prof.",name:"Carlos Eduardo",surname:"Molina-Guerrero",slug:"carlos-eduardo-molina-guerrero",fullName:"Carlos Eduardo Molina-Guerrero"},{id:"253197",title:"Dr.",name:"Alma Hortensia",surname:"Serafin Muñoz",slug:"alma-hortensia-serafin-munoz",fullName:"Alma Hortensia Serafin Muñoz"},{id:"253200",title:"Dr.",name:"Berenice",surname:"Noriega Luna",slug:"berenice-noriega-luna",fullName:"Berenice Noriega Luna"},{id:"253201",title:"Dr.",name:"Julio Cesar",surname:"Leal Vaca",slug:"julio-cesar-leal-vaca",fullName:"Julio Cesar Leal Vaca"},{id:"261952",title:"MSc.",name:"Aurelio",surname:"Alvarez-Vargas",slug:"aurelio-alvarez-vargas",fullName:"Aurelio Alvarez-Vargas"}],corrections:null},{id:"63025",title:"From a Sequential to a Continuous Approach for LVV-h7 Preparation during Enzymatic Proteolysis in a Microfluidic- Based Extraction Process",doi:"10.5772/intechopen.80228",slug:"from-a-sequential-to-a-continuous-approach-for-lvv-h7-preparation-during-enzymatic-proteolysis-in-a-",totalDownloads:857,totalCrossrefCites:0,totalDimensionsCites:0,hasAltmetrics:0,abstract:"Intensification of process is increasingly interesting in the context of recovery of industrial wastes. Among these compounds, animal blood is underexploited although it is an important source of bioactive peptides. LVV-h7 (LVVYPWTQRF) is one of these bioactive peptides from bovine haemoglobin hydrolysate. Our innovative approach consists of a continuous process involving at microfluidic scale for enzymatic proteolysis of bovine haemoglobin by pepsin, selective extraction of LVV-h7 to an organic solvent during the enzymatic reaction, followed by a second extraction to an aqueous phase for organic solvent recycling. Thus, the obtainment of pure LVV-h7 peptide with an efficient methodology of extraction and solvent recycling was proved.",signatures:"Kalim Belhacene, Ionela Ungureanu, Elena Grosu, Alexandra Blaga,\nPascal Dhulster and Renato Froidevaux",downloadPdfUrl:"/chapter/pdf-download/63025",previewPdfUrl:"/chapter/pdf-preview/63025",authors:[{id:"253535",title:"Prof.",name:"Renato",surname:"Froidevaux",slug:"renato-froidevaux",fullName:"Renato Froidevaux"},{id:"264585",title:"Dr.",name:"Kalim",surname:"Belhacene",slug:"kalim-belhacene",fullName:"Kalim Belhacene"},{id:"264586",title:"Ms.",name:"Ionela",surname:"Ungureanu",slug:"ionela-ungureanu",fullName:"Ionela Ungureanu"},{id:"264587",title:"Ms.",name:"Elena",surname:"Grosu",slug:"elena-grosu",fullName:"Elena Grosu"},{id:"264588",title:"Dr.",name:"Alexandra",surname:"Blaga",slug:"alexandra-blaga",fullName:"Alexandra Blaga"},{id:"264589",title:"Prof.",name:"Pascal",surname:"Dhulster",slug:"pascal-dhulster",fullName:"Pascal Dhulster"},{id:"267268",title:"Dr.",name:"Remi",surname:"Przybylski",slug:"remi-przybylski",fullName:"Remi Przybylski"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},subseries:null,tags:null},relatedBooks:[{type:"book",id:"9731",title:"Oxidoreductase",subtitle:null,isOpenForSubmission:!1,hash:"852e6f862c85fc3adecdbaf822e64e6e",slug:"oxidoreductase",bookSignature:"Mahmoud Ahmed Mansour",coverURL:"https://cdn.intechopen.com/books/images_new/9731.jpg",editedByType:"Edited by",editors:[{id:"224662",title:"Prof.",name:"Mahmoud Ahmed",surname:"Mansour",slug:"mahmoud-ahmed-mansour",fullName:"Mahmoud Ahmed Mansour"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10841",title:"Hydrolases",subtitle:null,isOpenForSubmission:!1,hash:"4e868cde273d65a7ff54b1817d640629",slug:"hydrolases",bookSignature:"Sajjad Haider, Adnan Haider and Angel Catalá",coverURL:"https://cdn.intechopen.com/books/images_new/10841.jpg",editedByType:"Edited by",editors:[{id:"110708",title:"Dr.",name:"Sajjad",surname:"Haider",slug:"sajjad-haider",fullName:"Sajjad Haider"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"371",title:"Abiotic Stress in Plants",subtitle:"Mechanisms and Adaptations",isOpenForSubmission:!1,hash:"588466f487e307619849d72389178a74",slug:"abiotic-stress-in-plants-mechanisms-and-adaptations",bookSignature:"Arun Shanker and B. Venkateswarlu",coverURL:"https://cdn.intechopen.com/books/images_new/371.jpg",editedByType:"Edited by",editors:[{id:"58592",title:"Dr.",name:"Arun",surname:"Shanker",slug:"arun-shanker",fullName:"Arun Shanker"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3092",title:"Anopheles mosquitoes",subtitle:"New insights into malaria vectors",isOpenForSubmission:!1,hash:"c9e622485316d5e296288bf24d2b0d64",slug:"anopheles-mosquitoes-new-insights-into-malaria-vectors",bookSignature:"Sylvie Manguin",coverURL:"https://cdn.intechopen.com/books/images_new/3092.jpg",editedByType:"Edited by",editors:[{id:"50017",title:"Prof.",name:"Sylvie",surname:"Manguin",slug:"sylvie-manguin",fullName:"Sylvie Manguin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"72",title:"Ionic Liquids",subtitle:"Theory, Properties, New Approaches",isOpenForSubmission:!1,hash:"d94ffa3cfa10505e3b1d676d46fcd3f5",slug:"ionic-liquids-theory-properties-new-approaches",bookSignature:"Alexander Kokorin",coverURL:"https://cdn.intechopen.com/books/images_new/72.jpg",editedByType:"Edited by",editors:[{id:"19816",title:"Prof.",name:"Alexander",surname:"Kokorin",slug:"alexander-kokorin",fullName:"Alexander Kokorin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2270",title:"Fourier Transform",subtitle:"Materials Analysis",isOpenForSubmission:!1,hash:"5e094b066da527193e878e160b4772af",slug:"fourier-transform-materials-analysis",bookSignature:"Salih Mohammed Salih",coverURL:"https://cdn.intechopen.com/books/images_new/2270.jpg",editedByType:"Edited by",editors:[{id:"111691",title:"Dr.Ing.",name:"Salih",surname:"Salih",slug:"salih-salih",fullName:"Salih Salih"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"117",title:"Artificial Neural Networks",subtitle:"Methodological Advances and Biomedical Applications",isOpenForSubmission:!1,hash:null,slug:"artificial-neural-networks-methodological-advances-and-biomedical-applications",bookSignature:"Kenji Suzuki",coverURL:"https://cdn.intechopen.com/books/images_new/117.jpg",editedByType:"Edited by",editors:[{id:"3095",title:"Prof.",name:"Kenji",surname:"Suzuki",slug:"kenji-suzuki",fullName:"Kenji Suzuki"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3828",title:"Application of Nanotechnology in Drug Delivery",subtitle:null,isOpenForSubmission:!1,hash:"51a27e7adbfafcfedb6e9683f209cba4",slug:"application-of-nanotechnology-in-drug-delivery",bookSignature:"Ali Demir Sezer",coverURL:"https://cdn.intechopen.com/books/images_new/3828.jpg",editedByType:"Edited by",editors:[{id:"62389",title:"PhD.",name:"Ali Demir",surname:"Sezer",slug:"ali-demir-sezer",fullName:"Ali Demir Sezer"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],ofsBooks:[]},correction:{item:{id:"79356",slug:"correction-to-chemical-composition-and-biological-activities-of-mentha-species",title:"Correction to: Chemical Composition and Biological Activities of Mentha Species",doi:null,correctionPDFUrl:"https://cdn.intechopen.com/pdfs/57158.pdf",downloadPdfUrl:"/chapter/pdf-download/57158",previewPdfUrl:"/chapter/pdf-preview/57158",totalDownloads:null,totalCrossrefCites:null,bibtexUrl:"/chapter/bibtex/57158",risUrl:"/chapter/ris/57158",chapter:{id:"54028",slug:"chemical-composition-and-biological-activities-of-mentha-species",signatures:"Fatiha Brahmi, Madani Khodir, Chibane Mohamed and Duez Pierre",dateSubmitted:"June 7th 2016",dateReviewed:"December 19th 2016",datePrePublished:null,datePublished:"March 15th 2017",book:{id:"5612",title:"Aromatic and Medicinal Plants",subtitle:"Back to Nature",fullTitle:"Aromatic and Medicinal Plants - Back to Nature",slug:"aromatic-and-medicinal-plants-back-to-nature",publishedDate:"March 15th 2017",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/5612.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"193281",title:"Dr.",name:"Fatiha",middleName:null,surname:"Brahmi",fullName:"Fatiha Brahmi",slug:"fatiha-brahmi",email:"fatiha.brahmi@univ-bejaia.dz",position:null,institution:{name:"University of Béjaïa",institutionURL:null,country:{name:"Algeria"}}},{id:"199693",title:"Prof.",name:"Khodir",middleName:null,surname:"Madani",fullName:"Khodir Madani",slug:"khodir-madani",email:"madani28dz@yahoo.fr",position:null,institution:null},{id:"199694",title:"Prof.",name:"Pierre",middleName:null,surname:"Duez",fullName:"Pierre Duez",slug:"pierre-duez",email:"pduez@umons.be",position:null,institution:null},{id:"203738",title:"Prof.",name:"Mohamed",middleName:null,surname:"Chibane",fullName:"Mohamed Chibane",slug:"mohamed-chibane",email:"chibanem@yahoo.fr",position:null,institution:null}]}},chapter:{id:"54028",slug:"chemical-composition-and-biological-activities-of-mentha-species",signatures:"Fatiha Brahmi, Madani Khodir, Chibane Mohamed and Duez Pierre",dateSubmitted:"June 7th 2016",dateReviewed:"December 19th 2016",datePrePublished:null,datePublished:"March 15th 2017",book:{id:"5612",title:"Aromatic and Medicinal Plants",subtitle:"Back to Nature",fullTitle:"Aromatic and Medicinal Plants - Back to Nature",slug:"aromatic-and-medicinal-plants-back-to-nature",publishedDate:"March 15th 2017",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/5612.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"193281",title:"Dr.",name:"Fatiha",middleName:null,surname:"Brahmi",fullName:"Fatiha Brahmi",slug:"fatiha-brahmi",email:"fatiha.brahmi@univ-bejaia.dz",position:null,institution:{name:"University of Béjaïa",institutionURL:null,country:{name:"Algeria"}}},{id:"199693",title:"Prof.",name:"Khodir",middleName:null,surname:"Madani",fullName:"Khodir Madani",slug:"khodir-madani",email:"madani28dz@yahoo.fr",position:null,institution:null},{id:"199694",title:"Prof.",name:"Pierre",middleName:null,surname:"Duez",fullName:"Pierre Duez",slug:"pierre-duez",email:"pduez@umons.be",position:null,institution:null},{id:"203738",title:"Prof.",name:"Mohamed",middleName:null,surname:"Chibane",fullName:"Mohamed Chibane",slug:"mohamed-chibane",email:"chibanem@yahoo.fr",position:null,institution:null}]},book:{id:"5612",title:"Aromatic and Medicinal Plants",subtitle:"Back to Nature",fullTitle:"Aromatic and Medicinal Plants - Back to Nature",slug:"aromatic-and-medicinal-plants-back-to-nature",publishedDate:"March 15th 2017",bookSignature:"Hany A. El-Shemy",coverURL:"https://cdn.intechopen.com/books/images_new/5612.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"54719",title:"Prof.",name:"Hany",middleName:null,surname:"El-Shemy",slug:"hany-el-shemy",fullName:"Hany El-Shemy"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},ofsBook:{item:{type:"book",id:"10765",leadTitle:null,title:"Environmental Management",subtitle:"Pollution, Habitat, Ecology, and Sustainability",reviewType:"peer-reviewed",abstract:"Environmental Management - Pollution, Habitat, Ecology, and Sustainability includes sixteen chapters that discuss pressing environmental issues in diverse locations around the world. Chapters discuss methods, technologies, analyses, and actions that may enlighten and enable decision-makers and managers in their quests for control of environmental problems. The authors present the facts and the challenges behind the assorted issues and offer new perspectives for contending with natural, social, economic, and political aspects of management.",isbn:"978-1-83962-547-3",printIsbn:"978-1-83962-546-6",pdfIsbn:"978-1-83962-548-0",doi:null,price:139,priceEur:155,priceUsd:179,slug:"environmental-management-pollution-habitat-ecology-and-sustainability",numberOfPages:308,isOpenForSubmission:!1,isSalesforceBook:!1,isNomenclature:!1,hash:"e5ba02fedd7c87f0ab66414f3b07de0c",bookSignature:"John P. Tiefenbacher",publishedDate:"March 23rd 2022",coverURL:"https://cdn.intechopen.com/books/images_new/10765.jpg",keywords:null,numberOfDownloads:2840,numberOfWosCitations:0,numberOfCrossrefCitations:1,numberOfDimensionsCitations:2,numberOfTotalCitations:3,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"January 12th 2021",dateEndSecondStepPublish:"February 9th 2021",dateEndThirdStepPublish:"April 10th 2021",dateEndFourthStepPublish:"June 29th 2021",dateEndFifthStepPublish:"August 28th 2021",dateConfirmationOfParticipation:null,remainingDaysToSecondStep:"2 years",secondStepPassed:!0,areRegistrationsClosed:!0,currentStepOfPublishingProcess:5,editedByType:"Edited by",kuFlag:!1,biosketch:"A geospatial scholar working at the interface of natural and human systems, collaborating internationally on innovative studies about hazards and environmental challenges. Dr. Tiefenbacher has published more than 200 papers on a diverse array of topics that examine perception and behaviors with regards to the application of pesticides, releases of toxic chemicals, environments of the U.S.-Mexico borderlands, wildlife hazards, and the geography of wine.",coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"73876",title:"Dr.",name:"John P.",middleName:null,surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher",profilePictureURL:"https://mts.intechopen.com/storage/users/73876/images/system/73876.jfif",biography:"Dr. John P. Tiefenbacher (Ph.D., Rutgers, 1992) is a Professor of Geography and Environmental Studies, at Texas State University. His research has focused on various aspects of hazards and environmental management. Dr. Tiefenbacher has published on a diverse array of topics that examine perception and behaviors with regard to the application of pesticides, releases of toxic chemicals, environments of the US–Mexico borderlands, wildlife hazards, and the geography of wine. More recently his work pertains to adaptation to climate change, spatial responses of wine growing to climate change, the geographies of viticulture and wine, and artificial intelligence and machine learning to predict patterns of natural processes.",institutionString:"Texas State University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"7",institution:{name:"Texas State University",institutionURL:null,country:{name:"United States of America"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"130",title:"Environmental Management",slug:"environmental-sciences-environmental-management"}],chapters:[{id:"77471",title:"Design and Development of Air Quality Monitoring System for Solapur City Using Smart Technologies: WSN and IoT",slug:"design-and-development-of-air-quality-monitoring-system-for-solapur-city-using-smart-technologies-ws",totalDownloads:296,totalCrossrefCites:0,authors:[{id:"292284",title:"Dr.",name:"Tabbsum",surname:"Mujawar",slug:"tabbsum-mujawar",fullName:"Tabbsum Mujawar"},{id:"300961",title:"Prof.",name:"Lalasaheb",surname:"Deshmukh",slug:"lalasaheb-deshmukh",fullName:"Lalasaheb Deshmukh"},{id:"350411",title:"Prof.",name:"P.",surname:"Prabhakar",slug:"p.-prabhakar",fullName:"P. Prabhakar"},{id:"414488",title:"Dr.",name:"Vijendra",surname:"Chaudhari",slug:"vijendra-chaudhari",fullName:"Vijendra Chaudhari"}]},{id:"78036",title:"An Analysis of Remote Sensing Data to Evaluate the Problem of Atmospheric Aerosol Pollution in Africa",slug:"an-analysis-of-remote-sensing-data-to-evaluate-the-problem-of-atmospheric-aerosol-pollution-in-afric",totalDownloads:198,totalCrossrefCites:0,authors:[{id:"346239",title:"Dr.",name:"Gerard",surname:"Rushingabigwi",slug:"gerard-rushingabigwi",fullName:"Gerard Rushingabigwi"},{id:"346241",title:"Dr.",name:"Celestin",surname:"Twizere",slug:"celestin-twizere",fullName:"Celestin Twizere"},{id:"346242",title:"Dr.",name:"Jean De Dieu",surname:"Ntawangaheza",slug:"jean-de-dieu-ntawangaheza",fullName:"Jean De Dieu Ntawangaheza"},{id:"346243",title:"Prof.",name:"Liguo",surname:"Sun",slug:"liguo-sun",fullName:"Liguo Sun"},{id:"428987",title:"Dr.",name:"Philibert",surname:"Nsengiyumva",slug:"philibert-nsengiyumva",fullName:"Philibert Nsengiyumva"}]},{id:"77472",title:"Managing Non-Sewered Sanitation for Achieving Sustainable Development Goal 6 in India",slug:"managing-non-sewered-sanitation-for-achieving-sustainable-development-goal-6-in-india",totalDownloads:203,totalCrossrefCites:1,authors:[{id:"345914",title:"Mr.",name:"Shubhagato",surname:"Dasgupta",slug:"shubhagato-dasgupta",fullName:"Shubhagato Dasgupta"},{id:"348405",title:"M.Sc.",name:"Neha",surname:"Agarwal",slug:"neha-agarwal",fullName:"Neha Agarwal"}]},{id:"77369",title:"Reducing Pollution of Stabilized Landfill Leachate by Mixing of Coagulants and Flocculants: A Comparative Study",slug:"reducing-pollution-of-stabilized-landfill-leachate-by-mixing-of-coagulants-and-flocculants-a-compara",totalDownloads:213,totalCrossrefCites:0,authors:[{id:"348130",title:"Dr.",name:"Abdelkader",surname:"Anouzla",slug:"abdelkader-anouzla",fullName:"Abdelkader Anouzla"},{id:"348450",title:"Dr.",name:"Mlika",surname:"Kastali",slug:"mlika-kastali",fullName:"Mlika Kastali"},{id:"348451",title:"Dr.",name:"Latifa",surname:"Mouhir",slug:"latifa-mouhir",fullName:"Latifa Mouhir"},{id:"348452",title:"Dr.",name:"Abdelaziz",surname:"Madinzi",slug:"abdelaziz-madinzi",fullName:"Abdelaziz Madinzi"},{id:"348749",title:"Prof.",name:"Salah",surname:"Souabi",slug:"salah-souabi",fullName:"Salah Souabi"},{id:"348750",title:"Dr.",name:"Abdeslam",surname:"Taleb",slug:"abdeslam-taleb",fullName:"Abdeslam Taleb"}]},{id:"80590",title:"Plastic Pollution in the Mediterranean and Public-Private Partnerships to Manage It - A Case Study in Lebanon",slug:"plastic-pollution-in-the-mediterranean-and-public-private-partnerships-to-manage-it-a-case-study-in-",totalDownloads:81,totalCrossrefCites:0,authors:[{id:"108542",title:"Dr.",name:"Michel Soto",surname:"Chalhoub",slug:"michel-soto-chalhoub",fullName:"Michel Soto Chalhoub"}]},{id:"79986",title:"The Impacts of Air Pressure Differences on Microclimatic Wind Comfort among Low-Rise Buildings in the Historical Urban Landscape of the Bay of Kotor Region, Montenegro",slug:"the-impacts-of-air-pressure-differences-on-microclimatic-wind-comfort-among-low-rise-buildings-in-th",totalDownloads:83,totalCrossrefCites:0,authors:[{id:"185967",title:"Associate Prof.",name:"Enes",surname:"Yasa",slug:"enes-yasa",fullName:"Enes Yasa"},{id:"440813",title:"Mr.",name:"Kadir",surname:"Özdemir",slug:"kadir-ozdemir",fullName:"Kadir Özdemir"}]},{id:"79157",title:"Trajectories of RNA Virus Mutation Hidden by Evolutionary Alternate Reality Thermodynamic Endpoints in Transformations in Response to Abiotic Habitat Stresses",slug:"trajectories-of-rna-virus-mutation-hidden-by-evolutionary-alternate-reality-thermodynamic-endpoints-",totalDownloads:126,totalCrossrefCites:0,authors:[{id:"337363",title:"Ms.",name:"Farida Hanna",surname:"Campbell",slug:"farida-hanna-campbell",fullName:"Farida Hanna Campbell"}]},{id:"76399",title:"Hunting and Deforestation: A Threat to the Existence of the Niger Delta Red Colobus Monkey (Procolobus epieni)",slug:"hunting-and-deforestation-a-threat-to-the-existence-of-the-niger-delta-red-colobus-monkey-em-procolo",totalDownloads:243,totalCrossrefCites:0,authors:[{id:"142349",title:"Dr.",name:"Lameed",surname:"Gbolagade Akeem",slug:"lameed-gbolagade-akeem",fullName:"Lameed Gbolagade Akeem"},{id:"460721",title:"Dr.",name:"Lateef",surname:"Funmilayo Lewiska",slug:"lateef-funmilayo-lewiska",fullName:"Lateef Funmilayo Lewiska"}]},{id:"77847",title:"Implications of Ethnoecological and Phytoecological Studies for the Sustainable Management of the Mozogo-Gokoro National Park (Cameroon)",slug:"implications-of-ethnoecological-and-phytoecological-studies-for-the-sustainable-management-of-the-mo",totalDownloads:178,totalCrossrefCites:0,authors:[{id:"143856",title:"Dr.",name:"Adamou",surname:"Ibrahima",slug:"adamou-ibrahima",fullName:"Adamou Ibrahima"},{id:"316426",title:"Dr.",name:"Rodrigue Constant",surname:"Sandjong Sani",slug:"rodrigue-constant-sandjong-sani",fullName:"Rodrigue Constant Sandjong Sani"},{id:"318179",title:"Dr.",name:"Mama",surname:"Ntoupka",slug:"mama-ntoupka",fullName:"Mama Ntoupka"},{id:"318180",title:"Prof.",name:"Toua",surname:"Vroumsia",slug:"toua-vroumsia",fullName:"Toua Vroumsia"}]},{id:"78728",title:"Ecological Restoration of Degraded Habitats of Jajang Iron and Manganese Ore Mines, Keonjhar, Odisha, India",slug:"ecological-restoration-of-degraded-habitats-of-jajang-iron-and-manganese-ore-mines-keonjhar-odisha-i",totalDownloads:177,totalCrossrefCites:0,authors:[{id:"347126",title:"Dr.",name:"Rabindra Kumar",surname:"Mishra",slug:"rabindra-kumar-mishra",fullName:"Rabindra Kumar Mishra"},{id:"350537",title:"Mr.",name:"Barun",surname:"Behera",slug:"barun-behera",fullName:"Barun Behera"},{id:"427428",title:"Dr.",name:"Anita",surname:"Dash",slug:"anita-dash",fullName:"Anita Dash"},{id:"429598",title:"Dr.",name:"Bidyut",surname:"Kumar Patra",slug:"bidyut-kumar-patra",fullName:"Bidyut Kumar Patra"}]},{id:"76073",title:"Integrating Ecological Site Descriptions with Soil Morphology to Optimize Forest Management: Three Missouri Case Studies",slug:"integrating-ecological-site-descriptions-with-soil-morphology-to-optimize-forest-management-three-mi",totalDownloads:212,totalCrossrefCites:0,authors:[{id:"185895",title:"Dr.",name:"Michael",surname:"Aide",slug:"michael-aide",fullName:"Michael Aide"},{id:"269286",title:"Dr.",name:"Christine",surname:"Aide",slug:"christine-aide",fullName:"Christine Aide"},{id:"269287",title:"Dr.",name:"Indi",surname:"Braden",slug:"indi-braden",fullName:"Indi Braden"}]},{id:"78370",title:"Economic Value of Cultural Ecosystem Services in India: A Review",slug:"economic-value-of-cultural-ecosystem-services-in-india-a-review",totalDownloads:158,totalCrossrefCites:0,authors:[{id:"275432",title:"Dr.",name:"Muniyandi",surname:"Balasubramanian",slug:"muniyandi-balasubramanian",fullName:"Muniyandi Balasubramanian"}]},{id:"78342",title:"The Challenges of Managing Water for Wetland Ecology, Flood Mitigation and Agriculture in the Upper Lunan Water, an Intensive Arable Catchment in Scotland",slug:"the-challenges-of-managing-water-for-wetland-ecology-flood-mitigation-and-agriculture-in-the-upper-l",totalDownloads:141,totalCrossrefCites:0,authors:[{id:"347738",title:"Dr.",name:"Andy",surname:"Vinten",slug:"andy-vinten",fullName:"Andy Vinten"},{id:"415973",title:"Mr.",name:"Iain",surname:"D.M. Gunn",slug:"iain-d.m.-gunn",fullName:"Iain D.M. Gunn"}]},{id:"77826",title:"Ensuring Water Availability in Future through Revival of Indian Traditional Water Culture",slug:"ensuring-water-availability-in-future-through-revival-of-indian-traditional-water-culture",totalDownloads:180,totalCrossrefCites:0,authors:[{id:"346148",title:"Dr.",name:"Yogranjan",surname:"Singh",slug:"yogranjan-singh",fullName:"Yogranjan Singh"},{id:"421094",title:"Mr.",name:"Sarthak",surname:"Pandey",slug:"sarthak-pandey",fullName:"Sarthak Pandey"},{id:"421095",title:"Dr.",name:"Amit Kumar",surname:"Goswami",slug:"amit-kumar-goswami",fullName:"Amit Kumar Goswami"}]},{id:"77233",title:"Necessity, Principle and Technique of Evaluation Model to Assess Sustainability of Oil Palm Plantation in Indonesia",slug:"necessity-principle-and-technique-of-evaluation-model-to-assess-sustainability-of-oil-palm-plantatio",totalDownloads:46,totalCrossrefCites:0,authors:[{id:"348631",title:"Associate Prof.",name:"Latief Mahir",surname:"Rachman",slug:"latief-mahir-rachman",fullName:"Latief Mahir Rachman"}]},{id:"77199",title:"The Increasing Importance of Environmental, Social and Governance (ESG) Investing in Combating Climate Change",slug:"the-increasing-importance-of-environmental-social-and-governance-esg-investing-in-combating-climate-",totalDownloads:306,totalCrossrefCites:0,authors:[{id:"346150",title:"Dr.",name:"Percy",surname:"Jinga",slug:"percy-jinga",fullName:"Percy Jinga"}]}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"418641",firstName:"Iva",lastName:"Ribic",middleName:null,title:"M.Sc.",imageUrl:"https://mts.intechopen.com/storage/users/418641/images/16830_n.png",email:"iva.r@intechopen.com",biography:"As an Author Service Manager my responsibilities include monitoring and facilitating all publishing activities for authors and editors. From chapter submission and review, to approval and revision, copyediting and design, until final publication, I work closely with authors and editors to ensure a simple and easy publishing process. I maintain constant and effective communication with authors, editors and reviewers, which allows for a level of personal support that enables contributors to fully commit and concentrate on the chapters they are writing, editing, or reviewing. I assist authors in the preparation of their full chapter submissions and track important deadlines and ensure they are met. I help to coordinate internal processes such as linguistic review, and monitor the technical aspects of the process. As an ASM I am also involved in the acquisition of editors. Whether that be identifying an exceptional author and proposing an editorship collaboration, or contacting researchers who would like the opportunity to work with IntechOpen, I establish and help manage author and editor acquisition and contact."}},relatedBooks:[{type:"book",id:"600",title:"Approaches to Managing Disaster",subtitle:"Assessing Hazards, Emergencies and Disaster Impacts",isOpenForSubmission:!1,hash:"e97caba8487382025a1e70eb85e4e390",slug:"approaches-to-managing-disaster-assessing-hazards-emergencies-and-disaster-impacts",bookSignature:"John Tiefenbacher",coverURL:"https://cdn.intechopen.com/books/images_new/600.jpg",editedByType:"Edited by",editors:[{id:"73876",title:"Dr.",name:"John P.",surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3054",title:"Approaches to Disaster Management",subtitle:"Examining the Implications of Hazards, Emergencies and Disasters",isOpenForSubmission:!1,hash:"0d6576de4f4c7fc7b8db5e91cba6dc28",slug:"approaches-to-disaster-management-examining-the-implications-of-hazards-emergencies-and-disasters",bookSignature:"John Tiefenbacher",coverURL:"https://cdn.intechopen.com/books/images_new/3054.jpg",editedByType:"Edited by",editors:[{id:"73876",title:"Dr.",name:"John P.",surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"865",title:"Perspectives on Nature Conservation",subtitle:"Patterns, Pressures and Prospects",isOpenForSubmission:!1,hash:"4a4d39cf2a0c2a9416049331b508aa88",slug:"perspectives-on-nature-conservation-patterns-pressures-and-prospects",bookSignature:"John Tiefenbacher",coverURL:"https://cdn.intechopen.com/books/images_new/865.jpg",editedByType:"Edited by",editors:[{id:"73876",title:"Dr.",name:"John P.",surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9846",title:"Spatial Variability in Environmental Science",subtitle:"Patterns, Processes, and Analyses",isOpenForSubmission:!1,hash:"cfa4fa7b982bbff46ffbe6fbdbffbdf1",slug:"spatial-variability-in-environmental-science-patterns-processes-and-analyses",bookSignature:"John P. Tiefenbacher and Davod Poreh",coverURL:"https://cdn.intechopen.com/books/images_new/9846.jpg",editedByType:"Edited by",editors:[{id:"73876",title:"Dr.",name:"John P.",surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8011",title:"Natural Hazards",subtitle:"Risk, Exposure, Response, and Resilience",isOpenForSubmission:!1,hash:"43ca8c43ab0963f6c43350764f696b63",slug:"natural-hazards-risk-exposure-response-and-resilience",bookSignature:"John P. Tiefenbacher",coverURL:"https://cdn.intechopen.com/books/images_new/8011.jpg",editedByType:"Edited by",editors:[{id:"73876",title:"Dr.",name:"John P.",surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9389",title:"Global Warming and Climate Change",subtitle:null,isOpenForSubmission:!1,hash:"435d35b33ec04fe921640a514feb19e4",slug:"global-warming-and-climate-change",bookSignature:"John P. Tiefenbacher",coverURL:"https://cdn.intechopen.com/books/images_new/9389.jpg",editedByType:"Edited by",editors:[{id:"73876",title:"Dr.",name:"John P.",surname:"Tiefenbacher",slug:"john-p.-tiefenbacher",fullName:"John P. Tiefenbacher"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7477",title:"Advances in Environmental Monitoring and Assessment",subtitle:null,isOpenForSubmission:!1,hash:"23d6e3704efd9ff5940bbbefc54d3b86",slug:"advances-in-environmental-monitoring-and-assessment",bookSignature:"Suriyanarayanan Sarvajayakesavalu",coverURL:"https://cdn.intechopen.com/books/images_new/7477.jpg",editedByType:"Edited by",editors:[{id:"237021",title:"Dr.",name:"Suriyanarayanan",surname:"Sarvajayakesavalu",slug:"suriyanarayanan-sarvajayakesavalu",fullName:"Suriyanarayanan Sarvajayakesavalu"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8834",title:"Managing Wildlife in a Changing World",subtitle:null,isOpenForSubmission:!1,hash:"a27827009edc70af81e12c10aa3e51dd",slug:"managing-wildlife-in-a-changing-world",bookSignature:"Jafari R. Kideghesho",coverURL:"https://cdn.intechopen.com/books/images_new/8834.jpg",editedByType:"Edited by",editors:[{id:"280695",title:"Prof.",name:"Jafari R.",surname:"Kideghesho",slug:"jafari-r.-kideghesho",fullName:"Jafari R. Kideghesho"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1591",title:"Infrared Spectroscopy",subtitle:"Materials Science, Engineering and Technology",isOpenForSubmission:!1,hash:"99b4b7b71a8caeb693ed762b40b017f4",slug:"infrared-spectroscopy-materials-science-engineering-and-technology",bookSignature:"Theophile Theophanides",coverURL:"https://cdn.intechopen.com/books/images_new/1591.jpg",editedByType:"Edited by",editors:[{id:"37194",title:"Dr.",name:"Theophile",surname:"Theophanides",slug:"theophile-theophanides",fullName:"Theophile Theophanides"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3161",title:"Frontiers in Guided Wave Optics and Optoelectronics",subtitle:null,isOpenForSubmission:!1,hash:"deb44e9c99f82bbce1083abea743146c",slug:"frontiers-in-guided-wave-optics-and-optoelectronics",bookSignature:"Bishnu Pal",coverURL:"https://cdn.intechopen.com/books/images_new/3161.jpg",editedByType:"Edited by",editors:[{id:"4782",title:"Prof.",name:"Bishnu",surname:"Pal",slug:"bishnu-pal",fullName:"Bishnu Pal"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"63594",title:"Physical Rehabilitation in the Management of Symptomatic Adult Scoliosis",doi:"10.5772/intechopen.81184",slug:"physical-rehabilitation-in-the-management-of-symptomatic-adult-scoliosis",body:'\n
Adult scoliosis refers to spinal curvature in excess of 10° after skeletal maturity. Common causes include adult idiopathic scoliosis (ADIS) and degenerative lumbar scoliosis (DLS). ADIS has its onset in childhood or adolescent. Degenerative lumbar scoliosis (DLS) is an adult-onset scoliosis brought about by degeneration of facet joints.
\nThe prevalence of adult scoliosis varies with age and studies, ranging from 8.3 to 68% [1, 2, 3, 4, 5]. Xu et al. evaluated 2395 subjects over the age of 40 and reported that 13.3% had degenerative lumbar scoliosis (DLS) [5]. The prevalence increases with age. For subjects over 80 years of age, the prevalence is 27.1% [5]. Kobayashi et al. evaluated 60 elder normal subjects over 12 years and reported the prevalence of adult scoliosis to be 36.3% [1]. Schwab et al. reported the highest prevalence of 68% in 75 patients over the age of 60 [4].
\nThe curve prevalence is inversely proportional to the curve magnitude. Majority of the curve is less than 10°. The prevalence of 10°, 10–20°, and >20° curves was reported to be 64, 44, and 24%, respectively [6].
\nOf the different curve patterns, the thoracolumbar scoliosis is associated with a higher prevalence of low back pain and functional impairment [7]. Also, these curves tend to progress. The rate of progression for lumbar or thoracolumbar single curve was 0.82/year (0.34–1.65°) for adult idiopathic scoliosis patients [8]. The rate of progression is higher for curve in excess of 30° [9, 10, 11]. This was supported by a recent study on the radiographic parameter risk factors of rapid progression in adolescents with Lenke V and VI idiopathic scoliosis [12]. The study showed that apical vertebral rotation ≥ III (according to the Nash-Moe classification), deviation of the apical vertebra ≥40 mm from the central sacral line in the lumbar curve, and a L5 tilt angle ≥10° (Figure 1) are associated with an increased risk of curve progression in adolescents [12].
\nThe radiographic parameters that have been found to increase the risk of progression in adolescents with Lenke 5 and 6 scoliosis. It is likely that the parameters also increase the risk of curvature progression in adults. (a) Refers to the magnitude of apical vertebral rotation. (b) Refers to the distance between the central sacral line and the center of the apex of the lumbar curve. (c) Refers to the tilt angle of L5. When (a) is ≥III (based on the Nash-Moe method of measuring vertebral rotation), (b) is ≥4 cm, and (c) is ≥10°, the risk of progression of the curve increases.
Likewise, DLS tends to progress but irrespective of the Cobb angle (Figure 2) [8]. For patients with DLS, the rate of progression was 1.64°/year (0.77–3.82°) [8]. A study which followed up 200 subjects over 50 years of age for 5 years showed that 73% of the curves progressed 3° per year [13] and that apical vertebral rotation ≥ III (according to the Nash-Moe classification), a Cobb angle >30°, lateral vertebral translation >6 mm, and L5 above the intercristal line predict curve progression [13, 14]. Osteoporosis, a coronal Cobb angle <30°, lumbar lordosis, and degenerative spondylolisthesis are not risk factors for curve progression [14].
\nThe progression of degenerative lumbar scoliosis can be dramatic. The scoliosis in the frontal lumbar film of this woman 66 years of age was mild, with Cobb angle of 18° and the apex at L3 (a). The scoliosis progressed markedly 7 years later, with Cobb angle measuring 30°. Laterolisthesis of L1 to the right and L3 to the left could be seen (b). Arthrotic changes were apparent in the right in an attempt to stabilize the curvature, which, nevertheless, progressed to 44° 2 years later with marked rotation of L2–L4 vertebrae (c).
With increase in life expectancy of the population [2, 15], it follows that the prevalence of adult scoliosis increases [2, 15] and with it the morbidity.
\nThere are many different causes of adult scoliosis. Majority of the adult scoliosis are adult idiopathic scoliosis (ADIS) and degenerative lumbar scoliosis (DLS). Other causes include neuromuscular conditions such as cerebral palsy, syringomyelia, and spinal dysraphism and congenital anomalies such as block vertebrae. Adult scoliosis may also arise from trauma, neoplastic disease, as well as iatrogenic causes such as simple decompression (laminectomy) or lumbar fusion procedures [16]. The following discussion will be limited to the commonly seen ADIS and DLS.
\nIdiopathic scoliosis, as its name implies, does not have any identifiable cause. When juveniles and adolescents who have idiopathic scoliosis reach adulthood or skeletal maturity, the scoliosis is then referred to as adult idiopathic scoliosis (ADIS).
\nThe etiology of DLS is multifactorial and is related to progressive degeneration of the lumbar spine, compression fracture, and reduced bone density and quality [16]. The asymmetrical disc degeneration, facet degeneration, and ligamentous laxity all contribute to laxity in the spinal column [7, 17], with resultant asymmetrical deformities of the lumbar spine in the axial, coronal, and sagittal planes [18, 19]. The sagittal imbalance is accentuated in the presence of osteopenia or osteoporosis [16].
\nThe mechanisms by which the scoliotic curves cause low back pain have not been clearly established. Pain can result from muscle overload, joint irritation, as well as nerve tension or compression. Initial complaints on the apex of the curvature are possibly a result of muscle overload, when the paravertebral muscles have to contract to maintain the spinal balance. With curve progression, joints become involved and the compressive, shear, and torsional forces concentrating in the concavity of the curve increase. Junctional segments are subjected to increased shear, favoring degenerative changes at these levels. When the shear force exerted on the junctional segments exceeds that of the restraining force, laterolisthesis may occur [20]. It is noteworthy that laterolisthesis is present even in mild lumbar scoliosis. In a study of 91 adults with lumbar idiopathic scoliosis, 9.75% of the patients were found to have laterolisthesis, despite the average lumbar Cobb angle being 16.5° [20]. The presence of lumbar laterolisthesis is associated with a higher frequency of back pain than do other curve patterns [10, 21]. When, however, osteophytes and traction spurs develop in those segments, the unstable segments may become stabilized with reduction in pain.
\nDepending on the level of involvement and anatomical configurations, nerve root entrapment may occur with radicular distress in the lower extremity. The nerve entrapment is usually present in the concavity of the curve, though it may also occur in the side of convexity. It is generally secondary to foraminal compression and pedicular kinking. With laterolisthesis, the pedicle migrates toward the side of concavity. The higher nerve root is thus stretched by the migrating pedicle (Figure 3); the lower nerve root similarly is stretched over the pedicle as it shifts laterally with the vertebral body above [22].
\nThe possible mechanism of nerve root entrapment in the concavity of the scoliotic curve. The laterolisthesis of the shaded vertebra to the left causes a downward migration of the left pedicle and exerts a pull on the nerve root. Owing to the lateral movement of the nerve root, the nerve root below is being stretched by the left pedicle. Thus a scoliosis can cause entrapment of nerve roots at two levels.
Many studies have shown that both ADIS and DLS may present with low back pain and radiculopathy. Yet, their characteristics differ [23]. ADIS patients usually have mechanical low back pain at an earlier age, at or around the age of 30. The pain is mechanical and seldom involves the leg [23].
\nIn contrast, DLS patients have different pain patterns (Table 1). They are usually in the 50–60 years of age [24]. Those under 50 years of age with lumbar scoliosis are rarely subjected to significant pain and disability. Onset of the low back pain may be sudden but is usually progressive. Most commonly, the patient complains of low back pain at the end of a strenuous day or after some unusual activities. Rest reduces the pain. Pain is usually present at the apex of the curve, the lumbosacral junction, and the concavity of the scoliotic spine [25, 26, 27]. Very rarely is the pain brought about by impingement of the lower ribs upon the iliac crest [25].
\n\n | Degenerative lumbar scoliosis (DLS) | \nAdult idiopathic scoliosis (ADIS) | \n
---|---|---|
Age range at presentation (years) | \n55–57 | \n25–56 | \n
Male/female incidence | \n41:59 | \n4:96 | \n
Symptoms | \nStenotic | \nMechanical | \n
The main difference in clinical presentation in patients with DLS and ADIS [24].
With progression of the condition, the patient may complain of radiating pain deep into the buttock and distally down the lower extremity, involving more than one dermatome with poorly defined boundaries [24]. Definite root entrapment is uncommon, and the incidence reported is 2.2% [26]. The severity of the complaint was found to be statistically significantly correlated with age. The older the patient, the more severe are the symptoms. A study of subjects over 50 years of age with DLS showed that 45 out of 200 patients (22.5%) had severe pain and neurological deficits [13].
\nThe relationship between the degree of lumbar curve and low back pain, however, has been controversial. Some authors [26, 27] reported that the greater the degree of scoliosis, the more is the pain. This is especially so for a curve that exceeds 45° [26]. In an analysis of pain pattern, Jackson and Simmons [27] found that the severity of low back pain varies with the level of scoliosis, the type of curve, and the degree of the curve. Lumbosacral, lumbar, and thoracolumbar curves were found to be more painful than thoracic curves. Comparing all curves, compensatory half curves are less painful, with one exception, viz., the left compensatory lumbosacral half curve. In the presence of a major and a compensatory curve, the pain usually localizes in the lower junctional segments and in the compensatory curve below the major deformity. In the presence of double major curves, however, the pain primarily affects the junctional areas below and between the major curves, with the lower one being more symptomatic [27].
\nRecent studies have shown that a coronal imbalance of more than 4–5 cm is associated with deterioration of pain and function scores in unoperated patients [28, 29]. Trunk shift is a predictor of surgery for patients with thoracolumbar and lumbar curvatures [29].
\nYet, other authors did not concur with this view [9, 30]. They found no correlation between the degree of scoliosis and back symptoms. Lafage et al. reported no correlation between clinical outcomes and coronal global balance [30]; the magnitude of the coronal deformity did not impact pain and disability [30].
\nRecently, it has been shown that sagittal spinal balance is more important than coronal curves in relation to clinical outcomes [31, 32, 33, 34, 35]. The severity of the symptoms in adult scoliosis patients is linearly related to the magnitude of the sagittal spinal imbalance [36]. A spinal vertical axis (SVA) in excess of 70 mm is associated with an increase in clinical symptoms [30, 36].
\nThe patient usually walks with a typical antalgic list, with forward flexion of the spine and flexion of both knees. This is more evident as weakness with ambulation increases. Also, the patient is noted to sit obliquely, maintaining weight on one buttock and twisting away from the panful side [24]. Loss of height can occur. It was reported that a loss of height from 4 to 24 cm in 1–22 years may occur [37].
\nExamination in standing position permits assessment of the deformities as well as the sagittal and coronal imbalance. Adult scoliosis patients are often seen with trunk shift in the coronal plane together with positive sagittal imbalance. Reduction in lumbar lordosis is generally evident as the pelvis is retroverted to compensate for the positive sagittal malalignment. In severe deformity when the pelvic retroversion is insufficient to compensate for the sagittal imbalance, hip and knee flexion may be required to restore the sagittal balance. In the long term, contractures of hip flexors may result, when they can be assessed by Thomas leg raise test [38].
\nInspection from the back may reveal the lumbar scoliosis. Generally, the pelvis shifts contralateral to the side of lumbar convexity. In the presence of left lumbar curvature, the pelvis shifts to the right and superiorly. The right pelvis is higher than the left. Conversely a right lumbar curvature is associated with shifting of the pelvis to the left [39]. This was confirmed by a study, which showed that 79% of patients with a single lumbar curve had the apex of the scoliosis opposite the side of high iliac crest [40]. The apparent leg length discrepancy that this created was reported in 87% of patients with degenerative lumbar scoliosis [40].
\nAssessment of the deformity may also be made in the sitting position to eliminate the confounding apparent leg length discrepancy or hip flexor contracture [38].
\nTo determine the coronal balance, the distance from the gluteal cleft to a plumb line dropped from C7 is measured. When the head and trunk are not centered over the gluteal cleft and the measurement (coronal balance) is in excess of 4 cm, the scoliosis may be poorly compensated and more likely to progress [28].
\nPalpation may or may not elicit tenderness in the low back [9]. When tenderness is present, it is generally found in the concavity of the curve and at the junction between the two curves [27].
\nNeurological examination generally shows that there is reduced sensation in poorly defined areas. The reflexes of the lower extremities, however, are generally within normal limits. With increase in pain and disability, however, paresthesia over the posterolateral thigh and leg in areas of L5 and S1 dermatomal distribution becomes more evident, and reflexes in the lower extremities may reduce and become absent [41]. Straight leg raising is rarely restricted.
\nPosteroanterior (PA) and lateral full spine radiographs are generally required. These enable assessment of global and regional spinopelvic alignment and assessment of the severity of the condition and the risk of curve progression.
\nTo determine the coronal balance, a central sacral line (CSL) is drawn vertically from the center of the sacrum. The distance from C7 to the CSL is a measure of the coronal balance. From the PA film, the Cobb angle and the pelvic obliquity can also be determined. To measure the coronal Cobb angle, the upper and lower most tilted vertebrae (end vertebrae) are determined. Tangent lines are then drawn on the superior end plate of the upper end vertebra and the inferior end plate of the lower end vertebra, respectively. Perpendicular lines are then drawn to these two lines. The angle of intersection is the Cobb angle. The location of the curve is determined by the level of the apex, which is defined as the disc or vertebra maximally displaced from the midline and is minimally angulated. When the apex is located at T12 or L1, the curve is termed thoracolumbar curve; when the apex is inferior to L1, the curve is known as lumbar curve.
\nIn DLS, the apex is generally located at the level of L2 and L3, with an associated distal fractional curve between L4 and S1. Compensatory curve when present is generally not structural and involves the thoracic and thoracolumbar areas [6]. Traction spurs and osteophytes are usually evident and are relatively large, situated on the concavity of the curve. Not uncommonly, laterolisthesis is present. In a long-term follow-up study, Weinstein and Ponseti [9] found that with time, marked translatory shift occurs between two vertebral segments in some lumbar and thoracolumbar curves. More severe structural deformities are characterized by laterolisthesis and rotatory subluxation, often at L3–L4 [20]. The shift took place at the lower end of the curve or at the transitional vertebra and is usually responsible for curve progression, which averages 3.3° in 10 years for both the thoracolumbar and lumbar curves [9, 20]. In mild curves with pelvic obliquity and more than 9 mm difference in hip levels, Giles and Taylor found an increased prevalence of L5 wedging in anteroposterior view, when compared with controls [42].
\nVertebral rotation can be determined clinically using the Nash-Moe method or more accurately using the Raimondi or Perdriolle methods (Figure 4), both of which have low intra- and inter-observer errors [43, 44, 45]. The measurement is important as studies have shown that vertebral rotation >33% is associated with an increased incidence of back pain [9].
\nMeasurement of the apical vertebral rotation using the Raimondi method. The distance from the edge of the convex side of the apical vertebra to the center of the convex pedicle (x) is determined. The width of the vertebra (x + y) is then measured. From these two readings, the vertebral rotation can be determined using a Raimondi torsiometer.
Many recent studies have shown the importance of sagittal profile in relation to clinical outcome [30, 36, 46]. Many spinopelvic measurements have been found to correlate with the pain and disability. Schwab et al. showed that sagittal vertical axis (SVA), pelvic incidence minus lumbar lordosis, and pelvic tilt are related to disability and pain scores [46].
\nSVA is a measure of the sagittal imbalance. It is the horizontal distance between a vertical plumb line from the body of C7 to the posterosuperior corner of S1. The mean SVA of asymptomatic subjects was reported to be 0.5 ± 2.5 cm, whereas an ideal SVA was defined to be ±5 cm [47]. A SVA in excess of 7 cm was shown to be associated with an increase in clinical symptoms [36]. The findings were confirmed by other independent studies [30, 46]. Lafage et al. reported a correlation between the SVA and Scoliosis Research Society (SRS) total scores and Oswestry Disability Index (ODI) scores [30].
\nThe SVA requires calibration of radiographs for measurement. To avoid the inherent error in measuring the offsets in non-calibrated radiographs, the T1 spinopelvic inclination (T1-SPI) angle may be used instead of SVA [30]. It is the angle subtended by a vertical plumb line from the center of T1 and a line drawn to bicoxofemoral axes (Figure 5). The angle has been shown to correlate with the health-related quality of life (HRQOL) scores [30]. Recently, Propopsalitis et al. (2014) proposed a novel radiographic measure of global spinal alignment, the T1 pelvic angle (TPA) [48]. It is the angle subtended by the lines connecting the bicoxofemoral axis to the center of T1 and the midpoint of the sacral end plate. Studies have shown that the measurement does not vary with pelvic retroversion or other postural compensatory mechanisms [48]. TPA was found to correlate with HRQOL scores. Treatment should attempt to reduce the TPA to <14°. Angle in excess of 20° corresponded to severe disability [48].
\nThe different methods of measuring global spinopelvic alignment. The sagittal vertical axis (a), the T1 spinopelvic inclination (T1-SPI) (b), and the T1 pelvic angle (TPA) (c).
The pelvic incidence (PI) is also another important pelvic parameter that needs to be measured. It is a constant morphological parameter which has been shown to influence lumbar alignment. It is the angle subtended by the line connecting the midpoint of the bicoxofemoral axes and that of the sacral end plate and the perpendicular line to the latter. It should approximately match the lumbar lordosis (LL) (PI-LL = ±9°). A pelvic incidence-lumbar lordosis mismatch (PI-LL) in excess of 10° was reported to correlate with disability [46].
\nThe PI is the sum of the pelvic tilt (PT) and sacral slope (SS) which are dynamic pelvic parameters that measure pelvic version, a compensatory mechanism to help maintain an upright posture in the setting of sagittal malalignment. The pelvic tilt is the angle subtended by the line connecting the midpoint of the bicoxofemoral axes and that of the sacral end plate and the vertical reference line extending upward from the femoral head axis. A positive sagittal imbalance as signified by an increased SVA is generally compensated by an increase in the pelvic tilt. A pelvic tilt of >22° is associated with disability [46].
\nIn the presence of signs and findings of nerve root entrapment and intermittent claudication, referral for magnetic resonance imaging may be necessary to rule out the possibility of spinal cord impingement, spinal canal stenosis, lateral recess stenosis, or intraspinal lesions.
\nWhen osteoporosis is suspected, the patient should be referred for bone density assessment by dual-energy X-ray absorptiometry (DEXA) or the radiation-free echographic ultrasound [49], as reduction in bone density has been found to be lower in DLS patients when compared with normal controls with no scoliosis [5]. Also, bone mineral density (BMD) was found to correlate negatively with the scoliosis angle [50]. Furthermore, DLS patients with a lumbar curve in excess of 20° were found to have lower BMD than those with lumbar curves less than 20° [5].
\nTreatment is generally conservative, particularly for patients who do not have rapidly progressive curves or significant neurological symptoms [6, 23, 51, 52]. Nonsteroidal anti-inflammatory drugs (NSAIDs), analgesics, manipulation, acupuncture, physiotherapy, and steroid injection were generally used to treat the low back pain and the accompanied radiculopathy [52, 53]. Outcome, however, was not satisfactory [52, 53]. A systematic review in 2007 showed that there was little evidence in support of these treatments in the management of adult scoliosis [52]. The studies identified level IV evidence for physical therapy, chiropractic care, and bracing and level III evidence for steroid injections [52]. Studies showed that the long-term successful rate of conservative treatment of symptomatic scoliosis was only 27% [33, 54].
\nThe above treatments aim at pain reduction and stabilization of the curve, but not at the sagittal imbalance which is so often seen in patients with DLS. Recent studies have shown that physiotherapeutic scoliosis-specific exercises (PSSE), mirror image exercises, and chiropractic manipulation together with multimodal rehabilitation reduced pain and disability ratings in ADIS patients with thoracolumbar and lumbar curves [55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67]. Also, bracing is able to stabilize progressive curves in 80% of the adults with scoliosis [68].
\nIn the past 15 years, many different exercises and rehabilitation approaches to ADIS have been investigated. These include exercise, manipulation, and multimodal rehabilitation approaches [55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 69]. Exercises studied include yoga (side plank), Pilates, the side-shift and hitch exercise, the active self-correction, the Chiropractic BioPhysics® (CBP) mirror image, the FED, the Scientific Exercises Approach to Scoliosis (SEAS), and the Schroth Best Practice® (SBP®) program (Table 2). Other rehabilitation techniques investigated include the gravity traction, the weighting system, and manipulation [58, 62, 69]. These interventions have all been reported to reduce pain, disability, and the curves in ADIS.
\nStudies | \nAuthors | \nNo | \nAge | \nTypes of scoliosis | \nIntervention | \nPI | \nOutcome | \n
---|---|---|---|---|---|---|---|
Case report/series | \nMorningstar 2006 [26] | \n3 | \n23–37 | \nADIS (TH) | \nChiropractic and rehab | \n<12 weeks | \nReduced curves (35 → 22°; 22 → 8°; 37 → 21°) | \n
Negrini 2008 [21] | \n1 | \n25 | \nADIS (DM) | \nSEAS | \n1 year | \nReduced curve (47 → 28.5°) | \n|
Yang 2015 [22] | \n1 | \n26 | \nADIS (TH) | \nSchroth + physio | \n8 weeks | \nReduced curve (20.5 → 16.4°) | \n|
Lebel 2016 [24] | \n1 | \n23 | \nADIS (TH) | \nSchroth | \nMore than 1 year | \nReduced LBP and curve (70 → 58°; 48 → 43°) | \n|
Harrison 2017 [18] | \n5 | \n17–45 | \nADIS (TL or L) | \nCBP® + manipulation | \n18–84 visits | \nReduced curves in 60% | \n|
Haggard 2017 [25] | \n1 | \n15 | \nAIS (TL) | \nCBP® + manipulation | \n24 visits | \nReduced LBP and curve after failure of chiropractic tx (27 → 8°) | \n|
Cohort | \nBarrios 2002 [15] | \n30 | \n25–55 | \nADIS (MX) | \nFED device | \n20 = 60 sessions | \nReduced back pain and curve (35 → 33°) | \n
Maruyama 2002 [17] | \n69 | \n11–27 | \nAIS and ADIS | \nSide shift and hitch | \nMean 4.2 years | \nTL: (24.5 → 22.9°) | \n|
Morningstar 2004 [20] | \n19 | \n15–65 | \nADIS (MX) | \nChiropractic and rehab | \n4–6 weeks | \nReduced curve mean reduction 17° | \n|
Morningstar 2011 [16] | \n28 | \n18–54 | \nADIS (MX) | \nChiropractic and rehab | \n6 months | \nReduced curves and disability rating; TL (39.2 → 22°) | \n|
Fishman 2014 [23] | \n25 | \n14–85 | \nADIS; DLS (MX) | \nSide plank | \n3–22 months | \nReduced 32% of the curve (37.2 → 25.3°) | \n|
Negrini 2015 [13] | \n34 | \n38 ± 11 | \nADIS (MX) | \nSEAS | \n2 years | \nReduced curves in 69% TL (49 → 46°) | \n|
Ng 2018 [19] | \n12 | \n59 ± 15 | \nADIS and DLS | \nSchroth Best Practice | \n9 months | \nReduced curves in 33% | \n|
RCT | \nMonticone 2016 [14] | \n130 | \n51.6 | \nADIS (MX) | \nSelf-correction and cognitive training | \n20 weeks | \nReduced disability and curves | \n
Studies on exercises and rehabilitation on the curves and pain in adult scoliosis patients.
No, number of patients; PI, period of intervention; ADIS, adult patients with idiopathic scoliosis; DLS, degenerative lumbar scoliosis; MX, mixed curve types; TH, thoracic scoliosis; DM, double major curves; TL, thoracolumbar curve; L, lumbar curve; CBP®, chiropractic biophysics; SEAS, Scientific Exercises Approach to Scoliosis.
A number of studies have reported a reduction of pain after scoliosis-specific exercises intervention [60, 64]. Yang reported a reduction in pain in a young female with ADIS with a thoracic curvature using the SBP®, together with the standard physiotherapy care [64]; the pain scale (visual analogue scale, VAS) of the patient reduced from 5 to 1. Lebel and Lebel reported a severe case of thoracic scoliosis treated by Schroth exercises [66]. After 9 months of exercises, the thoracic curve of the 23-year-old female patient with adolescent idiopathic scoliosis reduced from 70 to 58° and the lumbar curve from 48 to 43° [66]. There was a significant reduction in low back pain after 1 month of exercise [66]. Harrison and Oakley reported similar findings in five ADIS with thoracolumbar or lumbar curves, using the CBP® mirror image method [60]. All the five cases reported a reduction of VAS, with the most significant one dropping from 6 to 0 [60]. The findings agreed with the results of a randomized controlled trial which showed that stabilization exercises which included active self-correction, task-oriented activities, and cognitive behavior therapy improved the Oswestry Disability Index (ODI) of ADIS when compared to standard physiotherapy treatment [56].
\nMany studies similarly showed that rehabilitation and specific exercises improve curves in ADIS and patients with DLS [58, 60, 61]. Some studies have shown that manipulation together with multimodal rehabilitation reduced scoliosis curves. In a retrospective review, Morningstar et al. showed that chiropractic treatment together with multimodal rehabilitation for 4–6 weeks reduced the curves in all of the 19 adult patients with idiopathic scoliosis [62]. This was confirmed by a subsequent study, which reported that 6 months of multimodal treatment together with manipulation reduced scoliosis curves and disability ratings in 28 ADIS aged 18–54 [58]. Non-specific exercises and physiotherapeutic scoliosis-specific exercises (PSSE) have also been found to improve curvatures in ADIS [55, 65, 66]. Fishman et al. reported that performance of side plank exercises daily for as long as tolerable (around 2 minutes) on the side of scoliosis convexity reduced the curves in ADIS and DLS patients [65]. Daily side plank exercises for 3–22 months reduced curves significantly in 30% of the adult scoliosis patients [65]. Yet, the study included adolescents aged 14 as well as patients with a Cobb angle less than 10°, which is strictly speaking not scoliosis [65]. Negrini et al. reported the outcome of SEAS intervention in a 25-year-old female adult with progressive double major curve, which progressed by 10° in 6 years [63]. In the follow-up 1 year later, the curvatures were found to reduce significantly from 47 to 28.5°. The authors attributed the positive change to an improvement in postural collapse [63]. The results were supported by a retrospective cohort study conducted by the same group [55]. SEAS intervention for 2 years resulted in an improvement of the Cobb angle in 68% of the 34 ADIS aged 38 ± 11 [55]. The mean reduction in the Cobb angle was 4.6 ± 5.0°, with no differences based on the location of the curve, gender, and length of treatment [55]. Monticone et al. compared the outcome of stabilization exercises using self-correction, task-oriented activities, and cognitive behavior therapy with standard physiotherapy care, which consisted of active and passive mobilizations, stretching, and strengthening exercises of the spinal muscles in the treatment of ADIS [56]. In the randomized controlled trial which involved 130 patients with a mean age of 51.6, they found that the experimental group had a reduced Cobb angle after 20 weeks of intervention as compared to the control group. Schroth exercises have also been found to reduce curves in adult scoliosis patients [64, 66]. Ng et al., in a prospective study, showed that home-based SBP® program for 9 months reduced the thoracolumbar or lumbar curvature in over 30% of the ADIS and DLS patients [61]. Harrison and Oakley reported the outcome of CBP® mirror image method in the treatment of thoracolumbar and lumbar curves in five patients with ADIS. In 18–84 visits, the treatment improved the curvatures in 60% of the patients, when a reduction of ≥6° is regarded as an improvement [60]. The CBP® mirror image method was regarded as similar to Schroth exercises [60].
\nWhile there were many studies addressing the coronal curves in ADIS and DLS patients, there were very few studies addressing the impact of PSSE on the sagittal profile of the patients [61]. The effects of PSSE on the sagittal profile of this group of patients are thus uncertain.
\nHanging exercises should not be included as they have not been found useful [70]. Periodic axial spinal unloading using the LTX3000 lumbar rehabilitation system did not permanently affect the scoliosis; unloading of the spine temporarily reduced the scoliosis angle in adult scoliosis subjects, but with cessation of the intervention, the curves reverted back to the baseline level [70].
\nAs thoracolumbar and lumbar curves are frequently associated with pelvic shift and obliquity, with secondary apparent leg length discrepancy, it is tempting to apply sole lift on the side of the low pelvis. Lehnert-Schroth advised against the use of sole lift. Addition of the sole lift on the side of the low pelvis would cause spinal imbalance, as evidenced by the tilted gluteal cleft [39]. Instead, patients should be advised to contract the hip abductor on the side of the higher pelvis to level the pelvis [39]. The patients can also flex the knee on the side of the high iliac crest [71] or raise the heel on the side of the low iliac crest when standing at ease [72]. This would reduce the lumbar curve and the associated stress on the facet joints and the adjoining soft tissue structures.
\nThe effects of bracing in the treatment of adult scoliosis patients have been controversial [17, 68]. Some authors were of the opinion that brace does not halt curve progression and any pain relief provided is offset by associated deconditioning [7, 17]. Yet, recent studies have shown that spinal bracing stabilized the curves [68, 73, 74]. In a study which followed 158 adults with spinal deformities (ASD) treated by lordosing bivalve polyethylene overlapping brace for over 5 years showed that 24% of the curves reduced by more than 5°, 56% of the curves stabilized (±5°), and 20% worsened (>5°) [68]. Similarly, Palazzo et al. in a long-term follow-up study of 22 years showed that the progression of curves in ADIS and DLS patients reduced [74]. The yearly progression for curves in patients with DLS reduced from 1.47 to 0.24° per year and that for patients with ADIS from 0.7 to 0.24° per year [74]. de Mauroy suggested that the brace treatment is not only palliative; it treats lumbar instability by reducing the pressure in disc and stabilizing the lumbar area in lordosis [73].
\nAdult patients with low back pain and thoracolumbar and lumbar curves which have a high risk of progression or which are accompanied by sagittal imbalance are suggested to be treated by scoliosis-specific exercises, together with standard physiotherapy care. Exercises should target at improving the sagittal profile as well as the coronal curves. The exercises should preferably be supervised, as studies have shown that the physiotherapist-supervised Schroth Best Practice® (SBP®) exercises were associated with better outcome than home-based SBP® exercises [75]. In case of curve progression or pain, the patient should be prescribed a spinal brace. He or she should wear it 6–8 hours a day or as needed and perform the corrective scoliosis-specific exercises 3–4 times weekly to avoid deconditioning of the truncal muscles.
\nRecent studies showed that 46.6% of patients with DLS had sarcopenia involving the appendix and the trunk [76]. The trunk skeletal muscle mass index (SMI) was found to be significantly negatively correlated with SVA, PT, lumbar scoliosis, and apical vertebral rotation, suggesting that the reduction in trunk musculature was related to the stooped posture, pelvic retroversion, and lumbar scoliosis [76]. In view of the propensity of the DLS to progress, PSSE may also be taught to DLS patients who are asymptomatic as preventive measures.
\nIf all these interventions fail and the patient has signs and symptoms suggestive of clinically significant spinal stenosis, he or she should be referred for surgical management [77].
\nThe right and left nucleus accumbens (NAcc) are subcortical brain structures, located within the ventral striatum, that serve as a key limbic-motor interface, and have an important role in Pavlovian learning [1, 2]. This means that the right and left NAcc contribute to the regulation of emotional and motivation processing [3], incentive salience [4], pleasure, reward, and reinforcement [5]. In addition, neural reactivity to food- and/or drug-related reward cues evokes robust dopamine responses in the right and left NAcc [1]. This suggests that as parts of the brain reward system, the right and left NAcc function reflects how individuals respond to cues that signal a potential reward [1]. The right and left NAcc have also been implicated in obesity [2, 6], food addiction [7], tobacco, alcohol, and drug-seeking behaviors [8, 9, 10], obsessive-compulsive disorder [11, 12], depression [13], and anxiety [12].
To fulfill their functions, the right and left NAcc communicate with a number of large-scale brain networks such as the frontoparietal network (FPN) [14, 15, 16]. Neuroimaging studies have revealed some alterations of the connectivity between the NAcc and FPN as an indicator of altered NAcc function [15]. The FPN, also known as the central executive network (CEN), is a large-scale brain network that works with the NAcc, striatum, and basal ganglia [17]. FPN is implicated in the cognitive control [18], attention [19], problem-solving [19], and working memory [19]. Altered FPN function is linked to attention-deficit/hyperactivity disorder (ADHD) [18, 20], cocaine addiction [21], and several mental disorders [22] in children and adolescents. Disruption in the FPN during cognitive control tasks is a common element of schizophrenia, bipolar disorder, unipolar depression, anxiety, and substance use disorders [23].
Functional magnetic resonance imaging (fMRI) techniques have expanded what we know about functional connectivity across brain regions and networks. Resting-state functional connectivity (rsFC) investigates the temporal correlation of the spatially distributed brain regions’ activity at the resting state (i.e., when the participant has not engaged in an explicit task yet) [24]. rsFC allows us to identify spontaneous brain activity patterns, which can provide insight into neural activity patterns [25]. One advantage of rsFC is that it can explore networks not easily assessed during tasks and activities. Finally, rsFC tends to be free from bias in task selection and allows relatively easy data collection [25].
The frontoparietal-accumbal connectivity has a role in motivated behavior, food seeking, emotion regulation, food preference, obesity, eating disorders, and dopaminergic and reward systems of the brain [14, 15, 26, 27]. Decreased functional connectivity between the NAcc and the FPN is seen in depression [28]. An increase in the functional connectivity between the FPN and the NAcc is seen following mindfulness training [29]. Connectivity between the right NAcc and the FPN is also associated with substance use and cognitive control [30].
In comparison to peers with high parental education, children from low parental education have worse brain development [31]. The effects of parental education are well described on brain reward system, inhibitory control, cognitive development [32], language [33], executive function [33], and school achievement [32]. Low parental education is a risk factor for several mental, physical, and behavioral problems [32] including anxiety [34], depression [34], substance use problems [35, 36, 37], early initiation of sexual behavior [38], delinquency [39], obesity [40], and high blood pressure [41]. Parental education reduces children’s antisocial behaviors [42], externalizing problems [43], anxiety and depression [34], behavioral problems [44], psychiatric disorders [44], mental health problems [45], tobacco dependence and aggression [46], and school problems [47] in children and adolescents. High parental education is linked to the size and function of the NAcc [48], thalamus [49], hippocampus [50], amygdala [34], and cerebral cortex.
According to the Minorities’ Diminished Returns (MDRs) framework, parental education produces unequal outcomes for subpopulations [51, 52]. Additionally, based on the MDRs, ethnic minority children are less likely to have equal opportunities to gain from their parents’ education to ensure health outcomes [53, 54]. Stratification, racism, segregation, and marginalization are shown to decrease parental education’s effects on developmental outcomes for ethnic minorities [55, 56]. However, most of the MDRs’ literature is on Black, rather than Latino, children [49, 57, 58]. While we know about the poor attention [59], low school performance [60], high reward dependence [61], impulsivity [62], suicide [63], aggression [64], depression [65], and problem behaviors [66] of Black children with highly educated parents, very limited knowledge exists on Latino children.
According to Harrist and Criss, influences of parental conditions such as parental education are not additive to the effects of other social and behavioral determinants. There are complex moderated mediational influences of parental conditions that are beyond additive effects and may be sub-additive, synergistic, or multiplicative. These effects also vary across diverse groups of families with different socioeconomic and demographic backgrounds [67]. For example, parental education may have diminished influences on children brain development of Black than White families, in part because structural racism may reduce what parental education can do for a Black child [68]. Thus, there is an interest to test heterogeneity of the effects of parental conditions and to investigate the multiplicative and non-additive effects of parental resources and other factors that impact child development [67]. While these differential effects of parental education are shown for structure and function of some brain regions such as amygdala [69], thalamus [70], hippocampus [71], and cerebral cortex [68, 72, 73], less is known about heterogeneity of the effects of parental education on NAcc.
Previous neuroimaging studies have shown the association between parental education and children’s brain function and structure [56, 65]. Different from other socioeconomic status (SES) indicators such as income and poverty, parental education tends to represent an aspect of SES that is not represented by the presence of financial or material resources in the family [74]. Still, there continues to be a lack of studies on the effects of parental education on brain functional connectivity of the NAcc and FPN in group differences at the resting state. Likewise, it is necessary to examine the connectivity between the right and left NAcc and FPN that may reflect reward salience, reward process, cognitive control [75, 76, 77], and various cognition, emotions, and psychological problems [75, 76].
Using a sample of 9/10-year-old preadolescents from the Adolescent Brain Cognitive Development research (ABCD) study [75, 78], the present study had two aims: first, to investigate the correlation between parental education and rsFC between the right and left Nacc and FPN; and second, to examine ethnic heterogeneity in this correlation. We hypothesized that parental education would be positively associated with the functional connectivity of the right and left NAcc and FPN, and that there would be a weaker effect of parental education on the right and left NAcc functional connectivity with FPN for Latino than non-Latino preadolescents.
Data for this secondary analysis came from baseline (wave 1) of the Adolescent Brain Cognitive Development (ABCD) study. The ABCD is an unprecedented study in the examination of children’s brain development [75, 79]. The ABCD study is a longitudinal study of a diverse sample of children from age 9 to 10 to their early adulthood [80]. For more information regarding the ABCD sample, methods, measures, and imaging techniques, please see here [80].
The ABCD study is a multi-site longitudinal study that has recruited 11,875 children aged 9–10, from 21 cities across different states, to characterize their psychological and neurobiological development from early adolescence to early adulthood [78]. Most of the participants were recruited through schools across the 21 study sites [81]. Because of well-designed and performed sampling process, the ABCD study sample has generated a sample that although is not nationally representative, it is a balanced sample that has a strong proxy of US adolescents [81]. Thus, the ABCD sample is a close approximation of US children in terms of distribution of age, SES, ethnicity, sex, and urbanicity [81].
For this analysis, we only used the ABCD baseline sample. We included the ABCD study regardless of their race, ethnicity, and psychopathologies [81]. However, we limited the sample to those who had complete data on our variables and met satisfactory imaging quality. Our analytical n for the analyses *presented here is 7959.
The study variables included parental education (independent variable), children’s ethnicity (moderator), ethnicity, age, race, sex, parental marital status (confounders), and NAcc functional connectivity with the FPN, separately calculated for the right and left (dependent variables).
We used the Data Exploration and Analysis Portal (DEAP), a user-friendly online platform for multivariable analysis of the ABCD data. For multivariable analyses, two mixed-effects regression models were estimated (Supplementary Table).
The original ABCD research protocol received Institutional Review Board (IRB) approval in several institutions, including the University of California, San Diego (UCSD). Additionally, we received the ABCD data through an agreement between Charles R. Drew University and NIH/NDA. As the ABCD data were fully de-identified, our study was considered to be a nonhuman subject research. This exempted our study from a full review. Besides, all children in the ABCD study provided verbal assent to the protocol approved by the IRB, and all parents/caregivers signed the written informed consent form [80].
The present study used data from a large sample of 10,840 preadolescents between 9 and 10 years old (
N | n | n | n | |
---|---|---|---|---|
N | 10,840 | 8690 | 2150 | |
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |
Age (month) | 119.06 (7.51) | 119.18 (7.48) | 118.61 (7.58) | 0.002 |
Right NAcc functional connectivity with the FPN | −0.01 (0.15) | −0.01 (0.15) | −0.02 (0.15) | 0.043 |
Left NAcc functional connectivity with the FPN | −0.06 (0.17) | −0.06 (0.17) | −0.06 (0.17) | 0.421 |
Parental education | ||||
<HS diploma | 470 (4.3) | 184 (2.1) | 286 (13.3) | <0.001 |
HS diploma/GED | 970 (8.9) | 634 (7.3) | 336 (15.6) | |
Some college | 2815 (26.0) | 2071 (23.8) | 744 (34.6) | |
Bachelor | 2791 (25.7) | 2393 (27.5) | 398 (18.5) | |
Postgraduate degree | 3794 (35.0) | 3408 (39.2) | 386 (18.0) | |
Race | ||||
White | 7071 (65.2) | 5798 (66.7) | 1273 (59.2) | <0.001 |
Black | 1654 (15.3) | 1573 (18.1) | 81 (3.8) | |
Asian | 256 (2.4) | 235 (2.7) | 21 (1.0) | |
Other/mixed | 1859 (17.1) | 1084 (12.5) | 775 (36.0) | |
Sex | ||||
Female | 5194 (47.9) | 4162 (47.9) | 1032 (48.0) | 0.949 |
Male | 5646 (52.1) | 4528 (52.1) | 1118 (52.0) | |
Marital status | ||||
No | 3413 (31.5) | 2532 (29.1) | 881 (41.0) | <0.001 |
Yes | 7427 (68.5) | 6158 (70.9) | 1269 (59.0) |
Descriptive characteristics overall and by ethnicity (n = 10,840).
Notes: Source: Adolescent Brain Cognitive Development (ABCD) Study.
The fit of the mixed-effects regression model is summarized in Table 2. Models with the interaction effects between parental education and ethnicity showed a better fit when compared with main effect models that only included ethnicity and parental education. This shows that interaction between parental education and ethnicity contributes more to explaining the variance of the outcome for both the right and left NAcc with FPN connectivity.
Right | Left | |||
---|---|---|---|---|
Main effect | Interaction effect | Main effect | Interaction effect | |
N | 10,840 | 10,840 | 10,856 | 10,856 |
R-squared | 0.00451 | 0.00559 | 0.00347 | 0.00421 |
ΔR-squared | 0.00104 | 0.00241 | 0.00109 | 0.00189 |
ΔR-squared (%) | 0.1% | 0.24% | 0.11% | 0.19% |
Effect sizes and % variance explained by models.
As shown by Table 3 and Figure 1, parental education showed a positive association with the functional connectivity between the right and left NAcc with FPN. This positive correlation suggests that children with higher parental education have a stronger rsFC between the right NAcc and FPN.
Right | Left | ||||||||
---|---|---|---|---|---|---|---|---|---|
B | SE | Sig | b | SE | Sig | ||||
Parental education | |||||||||
HS diploma/GED | 0.01328 | 0.00859 | 0.1223612 | 0.00119 | 0.01272 | 0.925758 | |||
Some college | 0.01023 | 0.00772 | 0.1855986 | −0.00853 | 0.01186 | 0.4721566 | |||
Bachelor | 0.02173 | 0.00802 | 0.0067889 | ** | 0.00371 | 0.01208 | 0.7589529 | ||
Graduate degree | 0.01789 | 0.00800 | 0.0253812 | * | 0.00292 | 0.01203 | 0.8083342 | ||
Hispanic | −0.00353 | 0.00404 | 0.3819443 | −0.02965 | 0.01469 | 0.0436103 | * | ||
Race | |||||||||
Black | −0.01198 | 0.00471 | 0.0109603 | * | −0.01335 | 0.00483 | 0.0056677 | ** | |
Asian | −0.01446 | 0.00967 | 0.1350259 | −0.01465 | 0.00967 | 0.1298128 | |||
Other/mixed | −0.00560 | 0.00411 | 0.1724601 | −0.00572 | 0.00411 | 0.1634748 | |||
Age | 0.00021 | 0.00019 | 0.2671881 | 0.00022 | 0.00019 | 0.2638408 | |||
Sex | 0.00111 | 0.00292 | 0.7044723 | 0.00114 | 0.00292 | 0.6950323 | |||
Married family | 0.00662 | 0.00362 | 0.0670059 | # | 0.00688 | 0.00362 | 0.057242 | # | |
Parental education (HS Diploma/GED) × hispanic | 0.01551 | 0.01763 | 0.379094 | ||||||
Parental education (some college) × hispanic | 0.03629 | 0.01586 | 0.0221188 | * | |||||
Parental education (bachelor) × hispanic | 0.03788 | 0.01680 | 0.0241787 | * | |||||
Parental education (postgraduate degree) × hispanic | 0.01227 | 0.01677 | 0.4644527 |
Mixed-effects regressions on the effects of parental education and ethnicity on the functional connectivity between the frontoparietal network and nucleus accumbens (right).
Notes: Source: ABCD Study; Mixed-effects regression model is used; all covariates such as race, ethnicity, age, sex, family, and site were controlled.
Association between parental education and functional connectivity between the right NAcc and FPN overall and by ethnicity.
Table 4 and Figure 1 show that parental education had a stronger positive association between parental education and the right FPN resting-state functional connectivity in Hispanic children than non-Hispanic children.
Right | Left | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
B | SE | b | SE | |||||||
Parental education | ||||||||||
HS diploma/GED | 0.01432 | 0.00971 | 0.140307 | 0.04212 | 0.01439 | 0.0034347 | ** | |||
Some college | 0.02458 | 0.00873 | 0.0048772 | ** | 0.05058 | 0.01341 | 0.0001636 | *** | ||
Bachelor | 0.01292 | 0.00907 | 0.154451 | 0.03647 | 0.01367 | 0.0076431 | ** | |||
Graduate degree | 0.01748 | 0.00905 | 0.053342 | # | 0.04149 | 0.01361 | 0.0023007 | ** | ||
Hispanic | −0.00232 | 0.00457 | 0.612231 | 0.03703 | 0.01661 | 0.0257893 | * | |||
Race | ||||||||||
Black | 0.01807 | 0.00533 | 0.0007057 | *** | 0.01868 | 0.00546 | 0.0006308 | *** | ||
Asian | −0.00606 | 0.01091 | 0.578768 | −0.00603 | 0.01091 | 0.5804568 | ||||
Other/mixed | 0.01120 | 0.00465 | 0.0159763 | * | 0.01138 | 0.00465 | 0.0143508 | * | ||
Age | 0.00013 | 0.00022 | 0.541902 | 0.00014 | 0.00022 | 0.5346076 | ||||
Sex | 0.00767 | 0.00329 | 0.0195458 | * | 0.00759 | 0.00329 | 0.020868 | * | ||
Married family | 0.00036 | 0.00409 | 0.9291253 | 0.00030 | 0.00410 | 0.9418007 | ||||
Parental education (HS diploma/GED) × Hispanic | −0.05046 | 0.01993 | 0.0113542 | * | ||||||
Parental education (some college) × Hispanic | −0.04662 | 0.01793 | 0.0093157 | ** | ||||||
Parental education (bachelor) × Hispanic | −0.03491 | 0.01899 | 0.066009 | # | ||||||
Parental education (postgraduate degree) × Hispanic | −0.03745 | 0.01895 | 0.0482004 | * |
Mixed-effects regressions on the effects of parental education and ethnicity on the functional connectivity between the frontoparietal network and nucleus accumbens (left).
Notes: Source: ABCD Study; mixed-effects regression model is used; all covariates such as race, ethnicity, age, sex, family, and site were controlled.
As shown by Table 4 and Figure 2, parental education showed a positive association with the functional connectivity between the right and left NAcc with FPN. This positive correlation suggests that children with higher parental education have stronger rsFC between left NAcc and FPN.
Association between parental education and functional connectivity between the left NAcc and FPN overall and by ethnicity.
Table 4 and Figure 2 show that parental education had a negative interaction with ethnicity on the functional connectivity between the FPN and the left NAcc. This interaction was indicative of a weaker positive association between parental education and the left FPN-NAcc resting-state functional connectivity in Hispanic children than non-Hispanic children.
Our first aim showed a positive correlation between parental education and the NAcc resting-state functional connectivity with the FPN. Our second aim showed ethnic variation in the association between parental education and the right and left NAcc resting-state functional connectivity with the FPN. That is laterality, ethnicity, and parental education all show multiplicative effects on NAcc resting-state functional connectivity with the FPN. While we found a stronger correlation between parental education and the resting-state FPN’s functional connectivity with the right NAcc in Latino than non-Latino children, parental education showed a weaker association with the same connectivity for the left NAcc. The finding on the right NAcc contrasts with the MDRs, but the finding on the left NAcc supports the MDRs’ theory, which shows a weaker association between SES and brain development for marginalized and minority children than White children.
Our first finding is in agreement with other work showing the effects of parental education on brain structure [33], performance in several cognitive domains [82], and mental health problems, such as anxiety and depression [34]. However, most of what we know about SES effects are limited to specific brain regions [74, 83, 84], rather than rsFC. Past research has established a link between parental education and the size and activity of brain structures, such as the NAcc [48], amygdala [34], hippocampus [50], and thalamus [49]. In a study of examining a sample of 283 children and adolescents aged 4–18, higher parental education significantly predicted greater cortical thickness in the right anterior cingulate and left superior frontal gyrus [85]. Among 9475 children from the ABCD study, parental education was associated with reduced within and between sensorimotor network connectivity and increased sensorimotor network connectivity to frontal functional networks [76]. Furthermore, in line with our finding, higher parental education is shown to be linked to the development of frontoparietal connectivity in children [76]. Neurodevelopmental correlates of parental education may mediate why parental education is linked to behaviors [86], executive functions [33], reading ability [87], spatial skills, and inhibitory control [55]. Importantly, however, no studies to our knowledge have examined the associations between parental education and rsFC within the NAcc and FPN.
The effect of parental education on brain function can be explained by underlying mechanisms [88], such as cognitive stimulation available at home, parent–child interactions, and home learning environment, which all predict brain development [33, 88]. For example, more educated parents dedicate more time for their children in ways that seem to improve their children’s development [89, 90]. Likewise, more educated parents appear to have higher expectations for their children, provide more stimulating learning materials, use more complex language and speech patterns, and engage more with their children’s learning [89, 91]. These can help promote children’s cognitive development [90]. Furthermore, the skills obtained from formal education appear to enable parents to arrange their activities in ways that allow them to effectively accomplish their parenting goals [88].
The results of the right NAcc-FPN connectivity were not in line with what is shown from the comparison of Black and White children. According to the MDRs’ theory, parental education is more protective for White children than Black children. This finding was observed for the left NAcc-FPN connectivity. Similar to our finding on the left side, the effects of SES on attention [59], reward dependence [61], school performance [60], aggression [64], impulsivity [62], suicide [63], anxiety [92], and problem behaviors [66] are shown to be weaker in Black than White adolescents. This is the first study on the MDRs of parental education for NAcc functional connectivity with the FPN in Latino children. Even when MDRs exist, the right and left NAcc findings may vary largely.
Parental education has different and group-specific effects on children and youth brain development. This means that SES resources and ethnicity may have multiplicative, rather than additive, effects on the right NAcc resting-state functional connectivity with FPN. In this study and all the MDRs’ literature, ethnic variation in the SES effects is shaped by social rather than biological mechanisms. Thus, in our study, ethnicity is a social rather than biological factor. Consequently, the differential treatment of society, which is preventable, has resulted in the ethnic differences. Importantly, we consider race as a proxy of racism, such as labor market discrimination, low school quality, segregation, and differential policing, that results in reduced effects of parental education, even for more educated people [93].
The present study had some limitations. Firstly, a cross-sectional design limits any inference of causal links between parental education, ethnicity, and NAcc functional connectivity with the FPN. Secondly, we only studied parental education; other SES indicators were not included. Moreover, we did not examine how other factors, such as neighborhood context, stress, and social adversities, mitigate these effects across groups. Thirdly, Latino people are highly diverse. Cuban, Mexican, and Puerto Rican families differ in their history, culture, neighborhoods, SES, and other factors that may alter SES effects.
Although high NAcc resting-state functional connectivity with FPN is under the influence of parental education, ethnicity, and laterality, these effects are multiplicative rather than additive. This means that, while the parental education gradient was stronger for the right NAcc in Latino than non-Latino American preadolescents, the opposite finding was observed for the left NAcc. Due to qualitative differences in the lived conditions of ethnic groups in the United States, various subgroups may show different SES effects on brain development.
Right | Left | |
---|---|---|
Model 1 | rsfmri_cor_network.gordon_frontoparietal_subcort.aseg_accumbens.area.rh ∼ high.educ.bl + hisp + race.4level + age + sex + married.bl Random: ∼(1|rel_family_id) | rsfmri_cor_network.gordon_frontoparietal_subcort.aseg_accumbens.area.lh ∼ high.educ.bl + hisp + race.4level + age + sex + married.bl Random: ∼(1|rel_family_id) |
Model 2 | rsfmri_cor_network.gordon_frontoparietal_subcort.aseg_accumbens.area.rh ∼ high.educ.bl + hisp + race.4level + age + sex + married.bl + high.educ.bl * hisp Random: ∼(1|rel_family_id) | rsfmri_cor_network.gordon_frontoparietal_subcort.aseg_accumbens.area.lh ∼ high.educ.bl + hisp + race.4level + age + sex + married.bl + high.educ.bl * hispRandom: ∼(1|rel_family_id) |
Customer Satisfaction is of paramount importance at IntechOpen and we take all complaints very seriously. Our Authors, their institutions, and other purchasers, if dissatisfied with the service provided, or the product purchased, can file a written complaint to IntechOpen, 5 Princes Gate Court, London, SW7 2QJ, UK or via the following e-mail address: info@intechopen.com.
',metaTitle:"Customer Complaints",metaDescription:"Our authors, their institutions and other purchasers, if unsatisfied with the service provided or the product purchased, can file a written complaint at IN TECH d.o.o offices at Janeza Trdine 9, 51000 Rijeka, Croatia, or via the following e-mail address: info@intechopen.com.",metaKeywords:null,canonicalURL:null,contentRaw:'[{"type":"htmlEditorComponent","content":"Receipt of complaints will be acknowledged in writing and Intech Limited will respond fully to concerns within 15 business days.
\\n\\nCustomers have the right to terminate the contract without giving any reason (written notice of termination). The deadline for said termination is fourteen (14) days from the date of receipt of goods. Returns are at the expense of the Customer and must be made within the fourteen (14) days from the date of the written notice of termination. Intech Limited will process refunds to the Customer without undue delay.
\\n\\nIn the event that the Publisher ships damaged or misbound copies of products, or duplicate or incorrect copies of the products are received by the Customer, the Publisher will accept returns at the Publisher's expense, provided notice of such damaged or incorrect shipment is given to the Publisher within fourteen (14) working days from the date of receipt.
\\n\\nPublishing errors, including but not limited to typographical errors, having no significant effect on the editorial content or design characteristics of the products, cannot be considered a reason for rejecting payment or, as the case may be, modifying the agreed price.
\\n\\nAt the Publisher's request, the customer should provide evidence of the damaged or incorrect shipment. The Publisher will refund or ship the ordered products without delays.
\\n"}]'},components:[{type:"htmlEditorComponent",content:"Receipt of complaints will be acknowledged in writing and Intech Limited will respond fully to concerns within 15 business days.
\n\nCustomers have the right to terminate the contract without giving any reason (written notice of termination). The deadline for said termination is fourteen (14) days from the date of receipt of goods. Returns are at the expense of the Customer and must be made within the fourteen (14) days from the date of the written notice of termination. Intech Limited will process refunds to the Customer without undue delay.
\n\nIn the event that the Publisher ships damaged or misbound copies of products, or duplicate or incorrect copies of the products are received by the Customer, the Publisher will accept returns at the Publisher's expense, provided notice of such damaged or incorrect shipment is given to the Publisher within fourteen (14) working days from the date of receipt.
\n\nPublishing errors, including but not limited to typographical errors, having no significant effect on the editorial content or design characteristics of the products, cannot be considered a reason for rejecting payment or, as the case may be, modifying the agreed price.
\n\nAt the Publisher's request, the customer should provide evidence of the damaged or incorrect shipment. The Publisher will refund or ship the ordered products without delays.
\n"}]},successStories:{items:[]},authorsAndEditors:{filterParams:{},profiles:[{id:"396",title:"Dr.",name:"Vedran",middleName:null,surname:"Kordic",slug:"vedran-kordic",fullName:"Vedran Kordic",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/396/images/7281_n.png",biography:"After obtaining his Master's degree in Mechanical Engineering he continued his education at the Vienna University of Technology where he obtained his PhD degree in 2004. He worked as a researcher at the Automation and Control Institute, Faculty of Electrical Engineering, Vienna University of Technology until 2008. His studies in robotics lead him not only to a PhD degree but also inspired him to co-found and build the International Journal of Advanced Robotic Systems - world's first Open Access journal in the field of robotics.",institutionString:null,institution:{name:"TU Wien",country:{name:"Austria"}}},{id:"441",title:"Ph.D.",name:"Jaekyu",middleName:null,surname:"Park",slug:"jaekyu-park",fullName:"Jaekyu Park",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/441/images/1881_n.jpg",biography:null,institutionString:null,institution:{name:"LG Corporation (South Korea)",country:{name:"Korea, South"}}},{id:"465",title:"Dr.",name:"Christian",middleName:null,surname:"Martens",slug:"christian-martens",fullName:"Christian Martens",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Rheinmetall (Germany)",country:{name:"Germany"}}},{id:"479",title:"Dr.",name:"Valentina",middleName:null,surname:"Colla",slug:"valentina-colla",fullName:"Valentina Colla",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/479/images/358_n.jpg",biography:null,institutionString:null,institution:{name:"Sant'Anna School of Advanced Studies",country:{name:"Italy"}}},{id:"494",title:"PhD",name:"Loris",middleName:null,surname:"Nanni",slug:"loris-nanni",fullName:"Loris Nanni",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/494/images/system/494.jpg",biography:"Loris Nanni received his Master Degree cum laude on June-2002 from the University of Bologna, and the April 26th 2006 he received his Ph.D. in Computer Engineering at DEIS, University of Bologna. On September, 29th 2006 he has won a post PhD fellowship from the university of Bologna (from October 2006 to October 2008), at the competitive examination he was ranked first in the industrial engineering area. He extensively served as referee for several international journals. He is author/coauthor of more than 100 research papers. He has been involved in some projects supported by MURST and European Community. His research interests include pattern recognition, bioinformatics, and biometric systems (fingerprint classification and recognition, signature verification, face recognition).",institutionString:null,institution:null},{id:"496",title:"Dr.",name:"Carlos",middleName:null,surname:"Leon",slug:"carlos-leon",fullName:"Carlos Leon",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Seville",country:{name:"Spain"}}},{id:"512",title:"Dr.",name:"Dayang",middleName:null,surname:"Jawawi",slug:"dayang-jawawi",fullName:"Dayang Jawawi",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Technology Malaysia",country:{name:"Malaysia"}}},{id:"528",title:"Dr.",name:"Kresimir",middleName:null,surname:"Delac",slug:"kresimir-delac",fullName:"Kresimir Delac",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/528/images/system/528.jpg",biography:"K. Delac received his B.Sc.E.E. degree in 2003 and is currentlypursuing a Ph.D. degree at the University of Zagreb, Faculty of Electrical Engineering andComputing. His current research interests are digital image analysis, pattern recognition andbiometrics.",institutionString:null,institution:{name:"University of Zagreb",country:{name:"Croatia"}}},{id:"557",title:"Dr.",name:"Andon",middleName:"Venelinov",surname:"Topalov",slug:"andon-topalov",fullName:"Andon Topalov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/557/images/1927_n.jpg",biography:"Dr. Andon V. Topalov received the MSc degree in Control Engineering from the Faculty of Information Systems, Technologies, and Automation at Moscow State University of Civil Engineering (MGGU) in 1979. He then received his PhD degree in Control Engineering from the Department of Automation and Remote Control at Moscow State Mining University (MGSU), Moscow, in 1984. From 1985 to 1986, he was a Research Fellow in the Research Institute for Electronic Equipment, ZZU AD, Plovdiv, Bulgaria. In 1986, he joined the Department of Control Systems, Technical University of Sofia at the Plovdiv campus, where he is presently a Full Professor. He has held long-term visiting Professor/Scholar positions at various institutions in South Korea, Turkey, Mexico, Greece, Belgium, UK, and Germany. And he has coauthored one book and authored or coauthored more than 80 research papers in conference proceedings and journals. His current research interests are in the fields of intelligent control and robotics.",institutionString:null,institution:{name:"Technical University of Sofia",country:{name:"Bulgaria"}}},{id:"585",title:"Prof.",name:"Munir",middleName:null,surname:"Merdan",slug:"munir-merdan",fullName:"Munir Merdan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/585/images/system/585.jpg",biography:"Munir Merdan received the M.Sc. degree in mechanical engineering from the Technical University of Sarajevo, Bosnia and Herzegovina, in 2001, and the Ph.D. degree in electrical engineering from the Vienna University of Technology, Vienna, Austria, in 2009.Since 2005, he has been at the Automation and Control Institute, Vienna University of Technology, where he is currently a Senior Researcher. His research interests include the application of agent technology for achieving agile control in the manufacturing environment.",institutionString:null,institution:null},{id:"605",title:"Prof",name:"Dil",middleName:null,surname:"Hussain",slug:"dil-hussain",fullName:"Dil Hussain",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/605/images/system/605.jpg",biography:"Dr. Dil Muhammad Akbar Hussain is a professor of Electronics Engineering & Computer Science at the Department of Energy Technology, Aalborg University Denmark. Professor Akbar has a Master degree in Digital Electronics from Govt. College University, Lahore Pakistan and a P-hD degree in Control Engineering from the School of Engineering and Applied Sciences, University of Sussex United Kingdom. Aalborg University has Two Satellite Campuses, one in Copenhagen (Aalborg University Copenhagen) and the other in Esbjerg (Aalborg University Esbjerg).\n· He is a member of prestigious IEEE (Institute of Electrical and Electronics Engineers), and IAENG (International Association of Engineers) organizations. \n· He is the chief Editor of the Journal of Software Engineering.\n· He is the member of the Editorial Board of International Journal of Computer Science and Software Technology (IJCSST) and International Journal of Computer Engineering and Information Technology. \n· He is also the Editor of Communication in Computer and Information Science CCIS-20 by Springer.\n· Reviewer For Many Conferences\nHe is the lead person in making collaboration agreements between Aalborg University and many universities of Pakistan, for which the MOU’s (Memorandum of Understanding) have been signed.\nProfessor Akbar is working in Academia since 1990, he started his career as a Lab demonstrator/TA at the University of Sussex. After finishing his P. hD degree in 1992, he served in the Industry as a Scientific Officer and continued his academic career as a visiting scholar for a number of educational institutions. In 1996 he joined National University of Science & Technology Pakistan (NUST) as an Associate Professor; NUST is one of the top few universities in Pakistan. In 1999 he joined an International Company Lineo Inc, Canada as Manager Compiler Group, where he headed the group for developing Compiler Tool Chain and Porting of Operating Systems for the BLACKfin processor. The processor development was a joint venture by Intel and Analog Devices. In 2002 Lineo Inc., was taken over by another company, so he joined Aalborg University Denmark as an Assistant Professor.\nProfessor Akbar has truly a multi-disciplined career and he continued his legacy and making progress in many areas of his interests both in teaching and research. He has contributed in stochastic estimation of control area especially, in the Multiple Target Tracking and Interactive Multiple Model (IMM) research, Ball & Beam Control Problem, Robotics, Levitation Control. He has contributed in developing Algorithms for Fingerprint Matching, Computer Vision and Face Recognition. He has been supervising Pattern Recognition, Formal Languages and Distributed Processing projects for several years. He has reviewed many books on Management, Computer Science. Currently, he is an active and permanent reviewer for many international conferences and symposia and the program committee member for many international conferences.\nIn teaching he has taught the core computer science subjects like, Digital Design, Real Time Embedded System Programming, Operating Systems, Software Engineering, Data Structures, Databases, Compiler Construction. In the Engineering side, Digital Signal Processing, Computer Architecture, Electronics Devices, Digital Filtering and Engineering Management.\nApart from his Academic Interest and activities he loves sport especially, Cricket, Football, Snooker and Squash. He plays cricket for Esbjerg city in the second division team as an opener wicket keeper batsman. He is a very good player of squash but has not played squash since his arrival in Denmark.",institutionString:null,institution:null},{id:"611",title:"Prof.",name:"T",middleName:null,surname:"Nagarajan",slug:"t-nagarajan",fullName:"T Nagarajan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Universiti Teknologi Petronas",country:{name:"Malaysia"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:13389},{group:"region",caption:"Middle and South America",value:2,count:11661},{group:"region",caption:"Africa",value:3,count:4168},{group:"region",caption:"Asia",value:4,count:22334},{group:"region",caption:"Australia and Oceania",value:5,count:2019},{group:"region",caption:"Europe",value:6,count:33642}],offset:12,limit:12,total:135275},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{sort:"dateEndThirdStepPublish",topicId:"16"},books:[{type:"book",id:"11697",title:"Scoliosis",subtitle:null,isOpenForSubmission:!0,hash:"fa052443744b8f6ba5a87091e373bafe",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11697.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11699",title:"Neonatal Surgery",subtitle:null,isOpenForSubmission:!0,hash:"e52adaee8e54f51c2ba4972daeb410f7",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11699.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11730",title:"Midwifery",subtitle:null,isOpenForSubmission:!0,hash:"95389fcd878d0e929234c441744ba398",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11730.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11843",title:"Abortion Access",subtitle:null,isOpenForSubmission:!0,hash:"e07ed1706ed2bf6ad56aa7399d9edf1a",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11843.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11850",title:"Systemic Sclerosis",subtitle:null,isOpenForSubmission:!0,hash:"df3f380c5949c8d8c977631cac330f67",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11850.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11818",title:"Uveitis",subtitle:null,isOpenForSubmission:!0,hash:"f8c178e6f45ba7b500281005b5d5b67a",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11818.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11871",title:"Aortic Surgery",subtitle:null,isOpenForSubmission:!0,hash:"6559d38b53bc671745ac8bf9ef2bd1f7",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/11871.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11027",title:"Basics of Hypoglycemia",subtitle:null,isOpenForSubmission:!0,hash:"98ebc1e36d02be82c204b8fd5d24f97a",slug:null,bookSignature:"Dr. Alok Raghav",coverURL:"https://cdn.intechopen.com/books/images_new/11027.jpg",editedByType:null,editors:[{id:"334465",title:"Dr.",name:"Alok",surname:"Raghav",slug:"alok-raghav",fullName:"Alok Raghav"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12092",title:"Pancreatic Cancer",subtitle:null,isOpenForSubmission:!0,hash:"934ff1479446e52efd8d675a113fca63",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12092.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12093",title:"Germ Cell Tumors",subtitle:null,isOpenForSubmission:!0,hash:"a86ceba1cc2eddfb98df1f0bdd7970f3",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12093.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12114",title:"Bone Fractures",subtitle:null,isOpenForSubmission:!0,hash:"78d9847691b6f1a8454480e7c0dbaef4",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12114.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"12095",title:"Radiation Therapy",subtitle:null,isOpenForSubmission:!0,hash:"a4c8ee34ddd31ad65f143459a8f5300b",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/12095.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:26},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:7},{group:"topic",caption:"Business, Management and Economics",value:7,count:4},{group:"topic",caption:"Chemistry",value:8,count:16},{group:"topic",caption:"Computer and Information Science",value:9,count:18},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:8},{group:"topic",caption:"Engineering",value:11,count:41},{group:"topic",caption:"Environmental Sciences",value:12,count:5},{group:"topic",caption:"Immunology and Microbiology",value:13,count:8},{group:"topic",caption:"Materials Science",value:14,count:16},{group:"topic",caption:"Mathematics",value:15,count:9},{group:"topic",caption:"Medicine",value:16,count:66},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:2},{group:"topic",caption:"Neuroscience",value:18,count:3},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:7},{group:"topic",caption:"Physics",value:20,count:6},{group:"topic",caption:"Psychology",value:21,count:5},{group:"topic",caption:"Robotics",value:22,count:2},{group:"topic",caption:"Social Sciences",value:23,count:8},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:2}],offset:12,limit:12,total:145},popularBooks:{featuredBooks:[{type:"book",id:"7827",title:"Interpersonal Relationships",subtitle:null,isOpenForSubmission:!1,hash:"ebf41f4d17c75010eb3294cc8cac3d47",slug:"interpersonal-relationships",bookSignature:"Martha Peaslee Levine",coverURL:"https://cdn.intechopen.com/books/images_new/7827.jpg",editors:[{id:"186919",title:"Dr.",name:"Martha",middleName:null,surname:"Peaslee Levine",slug:"martha-peaslee-levine",fullName:"Martha Peaslee Levine"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10796",title:"Extracellular Vesicles",subtitle:"Role in Diseases, Pathogenesis and Therapy",isOpenForSubmission:!1,hash:"eb5407fcf93baff7bca3fae5640153a2",slug:"extracellular-vesicles-role-in-diseases-pathogenesis-and-therapy",bookSignature:"Manash K. Paul",coverURL:"https://cdn.intechopen.com/books/images_new/10796.jpg",editors:[{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10908",title:"Advances in Decision Making",subtitle:null,isOpenForSubmission:!1,hash:"126486f7f91e18e2e3539a32c38be7b1",slug:"advances-in-decision-making",bookSignature:"Fausto Pedro García Márquez",coverURL:"https://cdn.intechopen.com/books/images_new/10908.jpg",editors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",middleName:null,surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"95",title:"Applications and Experiences of Quality Control",subtitle:null,isOpenForSubmission:!1,hash:"4bcb22b1eee68210a977a97d5a0f363a",slug:"applications-and-experiences-of-quality-control",bookSignature:"Ognyan Ivanov",coverURL:"https://cdn.intechopen.com/books/images_new/95.jpg",editors:[{id:"22230",title:"Prof.",name:"Ognyan",middleName:null,surname:"Ivanov",slug:"ognyan-ivanov",fullName:"Ognyan Ivanov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"2160",title:"MATLAB",subtitle:"A Fundamental Tool for Scientific Computing and Engineering Applications - Volume 1",isOpenForSubmission:!1,hash:"dd9c658341fbd264ed4f8d9e6aa8ca29",slug:"matlab-a-fundamental-tool-for-scientific-computing-and-engineering-applications-volume-1",bookSignature:"Vasilios N. Katsikis",coverURL:"https://cdn.intechopen.com/books/images_new/2160.jpg",editors:[{id:"12289",title:"Prof.",name:"Vasilios",middleName:"N.",surname:"Katsikis",slug:"vasilios-katsikis",fullName:"Vasilios Katsikis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3560",title:"Advances in Landscape Architecture",subtitle:null,isOpenForSubmission:!1,hash:"a20614517ec5f7e91188fe8e42832138",slug:"advances-in-landscape-architecture",bookSignature:"Murat Özyavuz",coverURL:"https://cdn.intechopen.com/books/images_new/3560.jpg",editors:[{id:"93073",title:"Dr.",name:"Murat",middleName:null,surname:"Ozyavuz",slug:"murat-ozyavuz",fullName:"Murat Ozyavuz"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10739",title:"Global Decline of Insects",subtitle:null,isOpenForSubmission:!1,hash:"543783652b9092962a8fa4bed38eeb17",slug:"global-decline-of-insects",bookSignature:"Hamadttu Abdel Farag El-Shafie",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg",editors:[{id:"192142",title:"Dr.",name:"Hamadttu",middleName:null,surname:"Abdel Farag El-Shafie",slug:"hamadttu-abdel-farag-el-shafie",fullName:"Hamadttu Abdel Farag El-Shafie"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10911",title:"Higher Education",subtitle:"New Approaches to Accreditation, Digitalization, and Globalization in the Age of Covid",isOpenForSubmission:!1,hash:"223a02337498e535e967174c1f648fbc",slug:"higher-education-new-approaches-to-accreditation-digitalization-and-globalization-in-the-age-of-covid",bookSignature:"Lee Waller and Sharon Waller",coverURL:"https://cdn.intechopen.com/books/images_new/10911.jpg",editors:[{id:"263301",title:"Dr.",name:"Lee",middleName:null,surname:"Waller",slug:"lee-waller",fullName:"Lee Waller"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3568",title:"Recent Advances in Plant in vitro Culture",subtitle:null,isOpenForSubmission:!1,hash:"830bbb601742c85a3fb0eeafe1454c43",slug:"recent-advances-in-plant-in-vitro-culture",bookSignature:"Annarita Leva and Laura M. R. Rinaldi",coverURL:"https://cdn.intechopen.com/books/images_new/3568.jpg",editors:[{id:"142145",title:"Dr.",name:"Annarita",middleName:null,surname:"Leva",slug:"annarita-leva",fullName:"Annarita Leva"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3737",title:"MATLAB",subtitle:"Modelling, Programming and Simulations",isOpenForSubmission:!1,hash:null,slug:"matlab-modelling-programming-and-simulations",bookSignature:"Emilson Pereira Leite",coverURL:"https://cdn.intechopen.com/books/images_new/3737.jpg",editors:[{id:"12051",title:"Prof.",name:"Emilson",middleName:null,surname:"Pereira Leite",slug:"emilson-pereira-leite",fullName:"Emilson Pereira Leite"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"1770",title:"Gel Electrophoresis",subtitle:"Principles and Basics",isOpenForSubmission:!1,hash:"279701f6c802cf02deef45103e0611ff",slug:"gel-electrophoresis-principles-and-basics",bookSignature:"Sameh Magdeldin",coverURL:"https://cdn.intechopen.com/books/images_new/1770.jpg",editors:[{id:"123648",title:"Dr.",name:"Sameh",middleName:null,surname:"Magdeldin",slug:"sameh-magdeldin",fullName:"Sameh Magdeldin"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:4797},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"7827",title:"Interpersonal Relationships",subtitle:null,isOpenForSubmission:!1,hash:"ebf41f4d17c75010eb3294cc8cac3d47",slug:"interpersonal-relationships",bookSignature:"Martha Peaslee Levine",coverURL:"https://cdn.intechopen.com/books/images_new/7827.jpg",publishedDate:"July 27th 2022",numberOfDownloads:7175,editors:[{id:"186919",title:"Dr.",name:"Martha",middleName:null,surname:"Peaslee Levine",slug:"martha-peaslee-levine",fullName:"Martha Peaslee Levine"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",publishedDate:"July 27th 2022",numberOfDownloads:1981,editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10796",title:"Extracellular Vesicles",subtitle:"Role in Diseases, Pathogenesis and Therapy",isOpenForSubmission:!1,hash:"eb5407fcf93baff7bca3fae5640153a2",slug:"extracellular-vesicles-role-in-diseases-pathogenesis-and-therapy",bookSignature:"Manash K. Paul",coverURL:"https://cdn.intechopen.com/books/images_new/10796.jpg",publishedDate:"July 20th 2022",numberOfDownloads:2308,editors:[{id:"319365",title:"Assistant Prof.",name:"Manash K.",middleName:null,surname:"Paul",slug:"manash-k.-paul",fullName:"Manash K. Paul"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10908",title:"Advances in Decision Making",subtitle:null,isOpenForSubmission:!1,hash:"126486f7f91e18e2e3539a32c38be7b1",slug:"advances-in-decision-making",bookSignature:"Fausto Pedro García Márquez",coverURL:"https://cdn.intechopen.com/books/images_new/10908.jpg",publishedDate:"July 27th 2022",numberOfDownloads:1473,editors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",middleName:null,surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"95",title:"Applications and Experiences of Quality Control",subtitle:null,isOpenForSubmission:!1,hash:"4bcb22b1eee68210a977a97d5a0f363a",slug:"applications-and-experiences-of-quality-control",bookSignature:"Ognyan Ivanov",coverURL:"https://cdn.intechopen.com/books/images_new/95.jpg",publishedDate:"April 26th 2011",numberOfDownloads:318571,editors:[{id:"22230",title:"Prof.",name:"Ognyan",middleName:null,surname:"Ivanov",slug:"ognyan-ivanov",fullName:"Ognyan Ivanov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"2160",title:"MATLAB",subtitle:"A Fundamental Tool for Scientific Computing and Engineering Applications - Volume 1",isOpenForSubmission:!1,hash:"dd9c658341fbd264ed4f8d9e6aa8ca29",slug:"matlab-a-fundamental-tool-for-scientific-computing-and-engineering-applications-volume-1",bookSignature:"Vasilios N. Katsikis",coverURL:"https://cdn.intechopen.com/books/images_new/2160.jpg",publishedDate:"September 26th 2012",numberOfDownloads:271836,editors:[{id:"12289",title:"Prof.",name:"Vasilios",middleName:"N.",surname:"Katsikis",slug:"vasilios-katsikis",fullName:"Vasilios Katsikis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3560",title:"Advances in Landscape Architecture",subtitle:null,isOpenForSubmission:!1,hash:"a20614517ec5f7e91188fe8e42832138",slug:"advances-in-landscape-architecture",bookSignature:"Murat Özyavuz",coverURL:"https://cdn.intechopen.com/books/images_new/3560.jpg",publishedDate:"July 1st 2013",numberOfDownloads:243450,editors:[{id:"93073",title:"Dr.",name:"Murat",middleName:null,surname:"Ozyavuz",slug:"murat-ozyavuz",fullName:"Murat Ozyavuz"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10739",title:"Global Decline of Insects",subtitle:null,isOpenForSubmission:!1,hash:"543783652b9092962a8fa4bed38eeb17",slug:"global-decline-of-insects",bookSignature:"Hamadttu Abdel Farag El-Shafie",coverURL:"https://cdn.intechopen.com/books/images_new/10739.jpg",publishedDate:"July 20th 2022",numberOfDownloads:1582,editors:[{id:"192142",title:"Dr.",name:"Hamadttu",middleName:null,surname:"Abdel Farag El-Shafie",slug:"hamadttu-abdel-farag-el-shafie",fullName:"Hamadttu Abdel Farag El-Shafie"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"10911",title:"Higher Education",subtitle:"New Approaches to Accreditation, Digitalization, and Globalization in the Age of Covid",isOpenForSubmission:!1,hash:"223a02337498e535e967174c1f648fbc",slug:"higher-education-new-approaches-to-accreditation-digitalization-and-globalization-in-the-age-of-covid",bookSignature:"Lee Waller and Sharon Waller",coverURL:"https://cdn.intechopen.com/books/images_new/10911.jpg",publishedDate:"July 13th 2022",numberOfDownloads:2082,editors:[{id:"263301",title:"Dr.",name:"Lee",middleName:null,surname:"Waller",slug:"lee-waller",fullName:"Lee Waller"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"3568",title:"Recent Advances in Plant in vitro Culture",subtitle:null,isOpenForSubmission:!1,hash:"830bbb601742c85a3fb0eeafe1454c43",slug:"recent-advances-in-plant-in-vitro-culture",bookSignature:"Annarita Leva and Laura M. R. Rinaldi",coverURL:"https://cdn.intechopen.com/books/images_new/3568.jpg",publishedDate:"October 17th 2012",numberOfDownloads:256294,editors:[{id:"142145",title:"Dr.",name:"Annarita",middleName:null,surname:"Leva",slug:"annarita-leva",fullName:"Annarita Leva"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",isOpenForSubmission:!1,hash:"4af8830e463f89c57515c2da2b9777b0",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",bookSignature:"Dragana Gabrić and Marko Vuletić",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11328",title:"Botulinum Toxin",subtitle:"Recent Topics and Applications",isOpenForSubmission:!1,hash:"7dd05a316001cef143e209eda51387a7",slug:"botulinum-toxin-recent-topics-and-applications",bookSignature:"Suna Sabuncuoglu",coverURL:"https://cdn.intechopen.com/books/images_new/11328.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"270856",title:"Associate Prof.",name:"Suna",middleName:null,surname:"Sabuncuoglu",slug:"suna-sabuncuoglu",fullName:"Suna Sabuncuoglu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11085",title:"Polycystic Ovary Syndrome",subtitle:"Functional Investigation and Clinical Application",isOpenForSubmission:!1,hash:"3066dd3ff29e1fac072fd60b08d4d3e7",slug:"polycystic-ovary-syndrome-functional-investigation-and-clinical-application",bookSignature:"Zhengchao Wang",coverURL:"https://cdn.intechopen.com/books/images_new/11085.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"204883",title:"Dr.",name:"Zhengchao",middleName:null,surname:"Wang",slug:"zhengchao-wang",fullName:"Zhengchao Wang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10833",title:"Tumor Angiogenesis and Modulators",subtitle:null,isOpenForSubmission:!1,hash:"f29b575c46128b2da061ef7f9bd1070b",slug:"tumor-angiogenesis-and-modulators",bookSignature:"Ke Xu",coverURL:"https://cdn.intechopen.com/books/images_new/10833.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"59529",title:"Dr.",name:"Ke",middleName:null,surname:"Xu",slug:"ke-xu",fullName:"Ke Xu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11356",title:"Molecular Cloning",subtitle:null,isOpenForSubmission:!1,hash:"671c629dd86e97f0fb467b9e70e92296",slug:"molecular-cloning",bookSignature:"Sadık Dincer, Hatice Aysun Mercimek Takcı and Melis Sumengen Ozdenef",coverURL:"https://cdn.intechopen.com/books/images_new/11356.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"188141",title:"Prof.",name:"Sadik",middleName:null,surname:"Dincer",slug:"sadik-dincer",fullName:"Sadik Dincer"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7827",title:"Interpersonal Relationships",subtitle:null,isOpenForSubmission:!1,hash:"ebf41f4d17c75010eb3294cc8cac3d47",slug:"interpersonal-relationships",bookSignature:"Martha Peaslee Levine",coverURL:"https://cdn.intechopen.com/books/images_new/7827.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"186919",title:"Dr.",name:"Martha",middleName:null,surname:"Peaslee Levine",slug:"martha-peaslee-levine",fullName:"Martha Peaslee Levine"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10908",title:"Advances in Decision Making",subtitle:null,isOpenForSubmission:!1,hash:"126486f7f91e18e2e3539a32c38be7b1",slug:"advances-in-decision-making",bookSignature:"Fausto Pedro García Márquez",coverURL:"https://cdn.intechopen.com/books/images_new/10908.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"22844",title:"Prof.",name:"Fausto Pedro",middleName:null,surname:"García Márquez",slug:"fausto-pedro-garcia-marquez",fullName:"Fausto Pedro García Márquez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10669",title:"Corrosion",subtitle:"Fundamentals and Protection Mechanisms",isOpenForSubmission:!1,hash:"4a76d54f8a40fc2e7002a8d13fd617c1",slug:"corrosion-fundamentals-and-protection-mechanisms",bookSignature:"Fahmina Zafar, Anujit Ghosal and Eram Sharmin",coverURL:"https://cdn.intechopen.com/books/images_new/10669.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"89672",title:"Dr.",name:"Fahmina",middleName:null,surname:"Zafar",slug:"fahmina-zafar",fullName:"Fahmina Zafar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10677",title:"Advanced Topics of Topology",subtitle:null,isOpenForSubmission:!1,hash:"bf964c52f9e653fac20a7fcab58070e5",slug:"advanced-topics-of-topology",bookSignature:"Francisco Bulnes",coverURL:"https://cdn.intechopen.com/books/images_new/10677.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"92918",title:"Dr.",name:"Francisco",middleName:null,surname:"Bulnes",slug:"francisco-bulnes",fullName:"Francisco Bulnes"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"11195",title:"Recent Advances in Biometrics",subtitle:null,isOpenForSubmission:!1,hash:"2d32e33e0f499cb5241734bb75dd2a83",slug:"recent-advances-in-biometrics",bookSignature:"Muhammad Sarfraz",coverURL:"https://cdn.intechopen.com/books/images_new/11195.jpg",editedByType:"Edited by",publishedDate:"July 27th 2022",editors:[{id:"215610",title:"Prof.",name:"Muhammad",middleName:null,surname:"Sarfraz",slug:"muhammad-sarfraz",fullName:"Muhammad Sarfraz"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"770",title:"Renewable Energy",slug:"engineering-energy-engineering-renewable-energy",parent:{id:"117",title:"Energy Engineering",slug:"engineering-energy-engineering"},numberOfBooks:46,numberOfSeries:0,numberOfAuthorsAndEditors:1415,numberOfWosCitations:1855,numberOfCrossrefCitations:1365,numberOfDimensionsCitations:2999,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicId:"770",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"10457",title:"Entropy and Exergy in Renewable Energy",subtitle:null,isOpenForSubmission:!1,hash:"b0b25f4e04d94678a4b850c46ecf0ef6",slug:"entropy-and-exergy-in-renewable-energy",bookSignature:"Lin-Shu Wang, Wenping Cao and Shu-Bo Hu",coverURL:"https://cdn.intechopen.com/books/images_new/10457.jpg",editedByType:"Edited by",editors:[{id:"223830",title:"Prof.",name:"Lin-Shu",middleName:null,surname:"Wang",slug:"lin-shu-wang",fullName:"Lin-Shu Wang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9430",title:"Sustainable Energy Investment",subtitle:"Technical, Market and Policy Innovations to Address Risk",isOpenForSubmission:!1,hash:"944911e9a2154a0bf8b358cafc971f42",slug:"sustainable-energy-investment-technical-market-and-policy-innovations-to-address-risk",bookSignature:"Joseph Nyangon and John Byrne",coverURL:"https://cdn.intechopen.com/books/images_new/9430.jpg",editedByType:"Edited by",editors:[{id:"225597",title:"Dr.",name:"Joseph",middleName:null,surname:"Nyangon",slug:"joseph-nyangon",fullName:"Joseph Nyangon"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9385",title:"Renewable Energy",subtitle:"Technologies and Applications",isOpenForSubmission:!1,hash:"a6b446d19166f17f313008e6c056f3d8",slug:"renewable-energy-technologies-and-applications",bookSignature:"Tolga Taner, Archana Tiwari and Taha Selim Ustun",coverURL:"https://cdn.intechopen.com/books/images_new/9385.jpg",editedByType:"Edited by",editors:[{id:"197240",title:"Associate Prof.",name:"Tolga",middleName:null,surname:"Taner",slug:"tolga-taner",fullName:"Tolga Taner"}],equalEditorOne:{id:"186791",title:"Dr.",name:"Archana",middleName:null,surname:"Tiwari",slug:"archana-tiwari",fullName:"Archana Tiwari",profilePictureURL:"https://mts.intechopen.com/storage/users/186791/images/system/186791.jpg",biography:"Dr. Archana Tiwari is Associate Professor at Amity University, India. Her research interests include renewable sources of energy from microalgae and further utilizing the residual biomass for the generation of value-added products, bioremediation through microalgae and microbial consortium, antioxidative enzymes and stress, and nutraceuticals from microalgae. She has been working on algal biotechnology for the last two decades. She has published her research in many international journals and has authored many books and chapters with renowned publishing houses. She has also delivered talks as an invited speaker at many national and international conferences. Dr. Tiwari is the recipient of several awards including Researcher of the Year and Distinguished Scientist.",institutionString:"Amity University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"1",institution:{name:"Amity University",institutionURL:null,country:{name:"India"}}},equalEditorTwo:{id:"197609",title:"Prof.",name:"Taha Selim",middleName:null,surname:"Ustun",slug:"taha-selim-ustun",fullName:"Taha Selim Ustun",profilePictureURL:"https://mts.intechopen.com/storage/users/197609/images/system/197609.jpeg",biography:"Dr. Taha Selim Ustun received a Ph.D. in Electrical Engineering from Victoria University, Melbourne, Australia. He is a researcher with the Fukushima Renewable Energy Institute, AIST (FREA), where he leads the Smart Grid Cybersecurity Laboratory. Prior to that, he was a faculty member with the School of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. His current research interests include power systems protection, communication in power networks, distributed generation, microgrids, electric vehicle integration, and cybersecurity in smart grids. He serves on the editorial boards of IEEE Access, IEEE Transactions on Industrial Informatics, Energies, Electronics, Electricity, World Electric Vehicle and Information journals. Dr. Ustun is a member of the IEEE 2004 and 2800, IEC Renewable Energy Management WG 8, and IEC TC 57 WG17. He has been invited to run specialist courses in Africa, India, and China. He has delivered talks for the Qatar Foundation, the World Energy Council, the Waterloo Global Science Initiative, and the European Union Energy Initiative (EUEI). His research has attracted funding from prestigious programs in Japan, Australia, the European Union, and North America.",institutionString:"Fukushima Renewable Energy Institute, AIST (FREA)",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"1",totalChapterViews:"0",totalEditedBooks:"0",institution:{name:"National Institute of Advanced Industrial Science and Technology",institutionURL:null,country:{name:"Japan"}}},equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8871",title:"Renewable Energy",subtitle:"Resources, Challenges and Applications",isOpenForSubmission:!1,hash:"e00c59554fb355c16623c62064ecc3bb",slug:"renewable-energy-resources-challenges-and-applications",bookSignature:"Mansour Al Qubeissi, Ahmad El-kharouf and Hakan Serhad Soyhan",coverURL:"https://cdn.intechopen.com/books/images_new/8871.jpg",editedByType:"Edited by",editors:[{id:"241686",title:"Dr.",name:"Mansour",middleName:null,surname:"Al Qubeissi",slug:"mansour-al-qubeissi",fullName:"Mansour Al Qubeissi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7200",title:"Green Energy and Environment",subtitle:null,isOpenForSubmission:!1,hash:"72ad3cb35d7eb84855d6cb05c6e73897",slug:"green-energy-and-environment",bookSignature:"Eng Hwa Yap and Andrew Huey Ping Tan",coverURL:"https://cdn.intechopen.com/books/images_new/7200.jpg",editedByType:"Edited by",editors:[{id:"185577",title:"Associate Prof.",name:"Eng Hwa",middleName:null,surname:"Yap",slug:"eng-hwa-yap",fullName:"Eng Hwa Yap"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9441",title:"Ocean Thermal Energy Conversion (OTEC)",subtitle:"Past, Present, and Progress",isOpenForSubmission:!1,hash:"b0f6032c45ead7f1cb11bb488bfcd48d",slug:"ocean-thermal-energy-conversion-otec-past-present-and-progress",bookSignature:"Albert S. Kim and Hyeon-Ju Kim",coverURL:"https://cdn.intechopen.com/books/images_new/9441.jpg",editedByType:"Edited by",editors:[{id:"21045",title:"Prof.",name:"Albert S.",middleName:null,surname:"Kim",slug:"albert-s.-kim",fullName:"Albert S. Kim"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8896",title:"Sustainable Mobility",subtitle:null,isOpenForSubmission:!1,hash:"c5b28b438521dcd383df9b6e797ec462",slug:"sustainable-mobility",bookSignature:"Bernardo Llamas, Marcelo F. Ortega Romero and Eugenia Sillero",coverURL:"https://cdn.intechopen.com/books/images_new/8896.jpg",editedByType:"Edited by",editors:[{id:"169368",title:"Dr.",name:"Bernardo",middleName:null,surname:"Llamas",slug:"bernardo-llamas",fullName:"Bernardo Llamas"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9425",title:"Advanced Statistical Modeling, Forecasting, and Fault Detection in Renewable Energy Systems",subtitle:null,isOpenForSubmission:!1,hash:"f9dfa41155499eb62f21917c77db5f7c",slug:"advanced-statistical-modeling-forecasting-and-fault-detection-in-renewable-energy-systems",bookSignature:"Fouzi Harrou and Ying Sun",coverURL:"https://cdn.intechopen.com/books/images_new/9425.jpg",editedByType:"Edited by",editors:[{id:"197090",title:"Dr.",name:"Fouzi",middleName:null,surname:"Harrou",slug:"fouzi-harrou",fullName:"Fouzi Harrou"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10425",title:"Modeling, Simulation and Optimization of Wind Farms and Hybrid Systems",subtitle:null,isOpenForSubmission:!1,hash:"659adb2f2e862e51eab5b274c6673c30",slug:"modeling-simulation-and-optimization-of-wind-farms-and-hybrid-systems",bookSignature:"Karam Y. Maalawi",coverURL:"https://cdn.intechopen.com/books/images_new/10425.jpg",editedByType:"Edited by",editors:[{id:"18593",title:"Prof.",name:"Karam",middleName:"Youssef",surname:"Maalawi",slug:"karam-maalawi",fullName:"Karam Maalawi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7636",title:"Wind Solar Hybrid Renewable Energy System",subtitle:null,isOpenForSubmission:!1,hash:"49b63353c3d80ef6f449e55b1f6cee29",slug:"wind-solar-hybrid-renewable-energy-system",bookSignature:"Kenneth Eloghene Okedu, Ahmed Tahour and Abdel Ghani Aissaou",coverURL:"https://cdn.intechopen.com/books/images_new/7636.jpg",editedByType:"Edited by",editors:[{id:"172580",title:"Dr.",name:"Kenneth Eloghene",middleName:null,surname:"Okedu",slug:"kenneth-eloghene-okedu",fullName:"Kenneth Eloghene Okedu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7613",title:"Research Trends and Challenges in Smart Grids",subtitle:null,isOpenForSubmission:!1,hash:"ca836c407ba574b88af44b497d45d42b",slug:"research-trends-and-challenges-in-smart-grids",bookSignature:"Alfredo Vaccaro, Ahmed Faheem Zobaa, Prabhakar Karthikeyan Shanmugam and Kannaiah Sathish Kumar",coverURL:"https://cdn.intechopen.com/books/images_new/7613.jpg",editedByType:"Edited by",editors:[{id:"24725",title:"Dr.",name:"Alfredo",middleName:null,surname:"Vaccaro",slug:"alfredo-vaccaro",fullName:"Alfredo Vaccaro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8842",title:"Innovation in Energy Systems",subtitle:"New Technologies for Changing Paradigms",isOpenForSubmission:!1,hash:"75fdfb0206f7d487c3ac8dbe21dcef16",slug:"innovation-in-energy-systems-new-technologies-for-changing-paradigms",bookSignature:"Taha Selim Ustun",coverURL:"https://cdn.intechopen.com/books/images_new/8842.jpg",editedByType:"Edited by",editors:[{id:"272760",title:"Dr.",name:"Taha Selim",middleName:null,surname:"Ustun",slug:"taha-selim-ustun",fullName:"Taha Selim Ustun"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:46,seriesByTopicCollection:[],seriesByTopicTotal:0,mostCitedChapters:[{id:"48267",doi:"10.5772/59284",title:"Crystal Structures of CH3NH3PbI3 and Related Perovskite Compounds Used for Solar Cells",slug:"crystal-structures-of-ch3nh3pbi3-and-related-perovskite-compounds-used-for-solar-cells",totalDownloads:7637,totalCrossrefCites:57,totalDimensionsCites:130,abstract:null,book:{id:"4479",slug:"solar-cells-new-approaches-and-reviews",title:"Solar Cells",fullTitle:"Solar Cells - New Approaches and Reviews"},signatures:"Takeo Oku",authors:[{id:"31132",title:"Prof.",name:"Takeo",middleName:null,surname:"Oku",slug:"takeo-oku",fullName:"Takeo Oku"}]},{id:"8561",doi:"10.5772/8073",title:"Numerical Simulation of Solar Cells and Solar Cell Characterization Methods: the Open-Source on Demand Program AFORS-HET",slug:"numerical-simulation-of-solar-cells-and-solar-cell-characterization-methods-the-open-source-on-deman",totalDownloads:9823,totalCrossrefCites:32,totalDimensionsCites:66,abstract:null,book:{id:"3633",slug:"solar-energy",title:"Solar Energy",fullTitle:"Solar Energy"},signatures:"Rolf Stangl, Caspar Leendertz and Jan Haschke",authors:null},{id:"49438",doi:"10.5772/61280",title:"Perovskite Nanomaterials – Synthesis, Characterization, and Applications",slug:"perovskite-nanomaterials-synthesis-characterization-and-applications",totalDownloads:9192,totalCrossrefCites:24,totalDimensionsCites:57,abstract:"Inorganic perovskite-type oxides are fascinating nanomaterials for wide applications in catalysis, fuel cells, and electrochemical sensing. Perovskites prepared in the nanoscale have recently received extensive attention due to their catalytic nature when used as electrode modifiers. The catalytic activity of these oxides is higher than that of many transition metals compounds and even some precious metal oxides. They exhibit attractive physical and chemical characteristics such as electronic conductivity, electrically active structure, the oxide ions mobility through the crystal lattice, variations on the content of the oxygen, thermal and chemical stability, and supermagnetic, photocatalytic, thermoelectric, and dielectric properties.",book:{id:"5063",slug:"perovskite-materials-synthesis-characterisation-properties-and-applications",title:"Perovskite Materials",fullTitle:"Perovskite Materials - Synthesis, Characterisation, Properties, and Applications"},signatures:"Nada F. Atta, Ahmed Galal and Ekram H. El-Ads",authors:[{id:"30072",title:"Prof.",name:"Nada",middleName:null,surname:"F. Atta",slug:"nada-f.-atta",fullName:"Nada F. Atta"},{id:"174033",title:"Prof.",name:"Ahmed",middleName:null,surname:"Galal",slug:"ahmed-galal",fullName:"Ahmed Galal"},{id:"174034",title:"MSc.",name:"Ekram",middleName:null,surname:"El-Ads",slug:"ekram-el-ads",fullName:"Ekram El-Ads"},{id:"176164",title:"MSc.",name:"Ekram",middleName:null,surname:"Ekram H. El-Ads",slug:"ekram-ekram-h.-el-ads",fullName:"Ekram Ekram H. El-Ads"}]},{id:"37686",doi:"10.5772/50702",title:"Cu2ZnSnS4 Thin Film Solar Cells: Present Status and Future Prospects",slug:"cu2znsns4-thin-film-solar-cells-present-status-and-future-prospects",totalDownloads:10910,totalCrossrefCites:26,totalDimensionsCites:56,abstract:null,book:{id:"3118",slug:"solar-cells-research-and-application-perspectives",title:"Solar Cells",fullTitle:"Solar Cells - Research and Application Perspectives"},signatures:"Minlin Jiang and Xingzhong Yan",authors:[{id:"42857",title:"Dr.",name:"Xingzhong",middleName:null,surname:"Yan",slug:"xingzhong-yan",fullName:"Xingzhong Yan"},{id:"153957",title:"MSc.",name:"Minlin",middleName:null,surname:"Jiang",slug:"minlin-jiang",fullName:"Minlin Jiang"}]},{id:"70874",doi:"10.5772/intechopen.89494",title:"Social, Economic, and Environmental Impacts of Renewable Energy Resources",slug:"social-economic-and-environmental-impacts-of-renewable-energy-resources",totalDownloads:5006,totalCrossrefCites:27,totalDimensionsCites:54,abstract:"Conventional energy source based on coal, gas, and oil are very much helpful for the improvement in the economy of a country, but on the other hand, some bad impacts of these resources in the environment have bound us to use these resources within some limit and turned our thinking toward the renewable energy resources. The social, environmental, and economical problems can be omitted by use of renewable energy sources, because these resources are considered as environment-friendly, having no or little emission of exhaust and poisonous gases like carbon dioxide, carbon monooxide, sulfur dioxide, etc. Renewable energy is going to be an important source for power generation in near future, because we can use these resources again and again to produce useful energy. Wind power generation is considered as having lowest water consumption, lowest relative greenhouse gas emission, and most favorable social impacts. It is considered as one of the most sustainable renewable energy sources, followed by hydropower, photovoltaic, and then geothermal. As these resources are considered as clean energy resources, they can be helpful for the mitigation of greenhouse effect and global warming effect. Local employment, better health, job opportunities, job creation, consumer choice, improvement of life standard, social bonds creation, income development, demographic impacts, social bonds creation, and community development can be achieved by the proper usage of renewable energy system. Along with the outstanding advantages of these resources, some shortcomings also exist such as the variation of output due to seasonal change, which is the common thing for wind and hydroelectric power plant; hence, special design and consideration are required, which are fulfilled by the hardware and software due to the improvement in computer technology.",book:{id:"7636",slug:"wind-solar-hybrid-renewable-energy-system",title:"Wind Solar Hybrid Renewable Energy System",fullTitle:"Wind Solar Hybrid Renewable Energy System"},signatures:"Mahesh Kumar",authors:[{id:"309842",title:"Mr.",name:"Kamlesh",middleName:null,surname:"Kumar",slug:"kamlesh-kumar",fullName:"Kamlesh Kumar"}]}],mostDownloadedChaptersLast30Days:[{id:"70874",title:"Social, Economic, and Environmental Impacts of Renewable Energy Resources",slug:"social-economic-and-environmental-impacts-of-renewable-energy-resources",totalDownloads:4991,totalCrossrefCites:27,totalDimensionsCites:53,abstract:"Conventional energy source based on coal, gas, and oil are very much helpful for the improvement in the economy of a country, but on the other hand, some bad impacts of these resources in the environment have bound us to use these resources within some limit and turned our thinking toward the renewable energy resources. The social, environmental, and economical problems can be omitted by use of renewable energy sources, because these resources are considered as environment-friendly, having no or little emission of exhaust and poisonous gases like carbon dioxide, carbon monooxide, sulfur dioxide, etc. Renewable energy is going to be an important source for power generation in near future, because we can use these resources again and again to produce useful energy. Wind power generation is considered as having lowest water consumption, lowest relative greenhouse gas emission, and most favorable social impacts. It is considered as one of the most sustainable renewable energy sources, followed by hydropower, photovoltaic, and then geothermal. As these resources are considered as clean energy resources, they can be helpful for the mitigation of greenhouse effect and global warming effect. Local employment, better health, job opportunities, job creation, consumer choice, improvement of life standard, social bonds creation, income development, demographic impacts, social bonds creation, and community development can be achieved by the proper usage of renewable energy system. Along with the outstanding advantages of these resources, some shortcomings also exist such as the variation of output due to seasonal change, which is the common thing for wind and hydroelectric power plant; hence, special design and consideration are required, which are fulfilled by the hardware and software due to the improvement in computer technology.",book:{id:"7636",slug:"wind-solar-hybrid-renewable-energy-system",title:"Wind Solar Hybrid Renewable Energy System",fullTitle:"Wind Solar Hybrid Renewable Energy System"},signatures:"Mahesh Kumar",authors:[{id:"309842",title:"Mr.",name:"Kamlesh",middleName:null,surname:"Kumar",slug:"kamlesh-kumar",fullName:"Kamlesh Kumar"}]},{id:"42273",title:"Techno-Economic Analysis of Different Energy Storage Technologies",slug:"techno-economic-analysis-of-different-energy-storage-technologies",totalDownloads:8817,totalCrossrefCites:19,totalDimensionsCites:37,abstract:null,book:{id:"2154",slug:"energy-storage-technologies-and-applications",title:"Energy Storage",fullTitle:"Energy Storage - Technologies and Applications"},signatures:"Hussein Ibrahim and Adrian Ilinca",authors:[{id:"145865",title:"Dr.",name:"Hussein",middleName:null,surname:"Ibrahim",slug:"hussein-ibrahim",fullName:"Hussein Ibrahim"}]},{id:"67556",title:"A Review of Hybrid Renewable Energy Systems Based on Wind and Solar Energy: Modeling, Design and Optimization",slug:"a-review-of-hybrid-renewable-energy-systems-based-on-wind-and-solar-energy-modeling-design-and-optim",totalDownloads:2296,totalCrossrefCites:7,totalDimensionsCites:12,abstract:"In this chapter, an attempt is made to thoroughly review previous research work conducted on wind energy systems that are hybridized with a PV system. The chapter explores the most technical issues on wind drive hybrid systems and proposes possible solutions that can arise as a result of process integration in off-grid and grid-connected modes. A general introduction to wind energy, including how wind energy can be harvested, as well as recent progress and development of wind energy are discussed. With the special attention given to the issues related to the wind and photovoltaic (Wind-PV) systems. Throughout the chapter emphasis was made on modeling, design, and optimization and sensitivity analysis issues, and control strategies used to minimize risk as well as energy wastage. The reported reviewed results in this chapter will be a valuable researchers and practicing engineers involved in the design and development of wind energy systems.",book:{id:"7636",slug:"wind-solar-hybrid-renewable-energy-system",title:"Wind Solar Hybrid Renewable Energy System",fullTitle:"Wind Solar Hybrid Renewable Energy System"},signatures:"Salisu Muhammad Lawan and Wan Azlan Wan Zainal Abidin",authors:[{id:"286205",title:"Dr.",name:"Salisu",middleName:null,surname:"Muhammad Lawan",slug:"salisu-muhammad-lawan",fullName:"Salisu Muhammad Lawan"},{id:"286210",title:"Prof.",name:"Wan Azlan",middleName:null,surname:"Wan Zainal Abidin",slug:"wan-azlan-wan-zainal-abidin",fullName:"Wan Azlan Wan Zainal Abidin"}]},{id:"59381",title:"A Review of Recycling Processes for Photovoltaic Modules",slug:"a-review-of-recycling-processes-for-photovoltaic-modules",totalDownloads:3572,totalCrossrefCites:24,totalDimensionsCites:46,abstract:"The installations of photovoltaic (PV) solar modules are growing extremely fast. As a result of the increase, the volume of modules that reach the end of their life will grow at the same rate in the near future. It is expected that by 2050 that figure will increase to 5.5–6 million tons. Consequently, methods for recycling solar modules are being developed worldwide to reduce the environmental impact of PV waste and to recover some of the value from old modules. Current recycling methods can recover just a portion of the materials, so there is plenty of room for progress in this area. Currently, Europe is the only jurisdiction that has a strong and clear regulatory framework to support the PV recycling process. This review presents a summary of possible PV recycling processes for solar modules, including c-Si and thin-film technologies as well as an overview of the global legislation. So far, recycling processes of c-Si modules are unprofitable but are likely to be mandated in more jurisdictions. There is potential to develop new pathways for PV waste management industry development and offer employment and prospects for both public and private sector investors.",book:{id:"6691",slug:"solar-panels-and-photovoltaic-materials",title:"Solar Panels and Photovoltaic Materials",fullTitle:"Solar Panels and Photovoltaic Materials"},signatures:"Marina Monteiro Lunardi, Juan Pablo Alvarez-Gaitan, José I. Bilbao\nand Richard Corkish",authors:[{id:"233229",title:"Dr.",name:"Richard",middleName:null,surname:"Corkish",slug:"richard-corkish",fullName:"Richard Corkish"},{id:"233231",title:"Ms.",name:"Marina",middleName:null,surname:"Monteiro Lunardi",slug:"marina-monteiro-lunardi",fullName:"Marina Monteiro Lunardi"},{id:"242337",title:"Dr.",name:"Juan Pablo",middleName:null,surname:"Alvarez-Gaitan",slug:"juan-pablo-alvarez-gaitan",fullName:"Juan Pablo Alvarez-Gaitan"},{id:"242338",title:"Dr.",name:"Jose I.",middleName:null,surname:"Bilbao",slug:"jose-i.-bilbao",fullName:"Jose I. Bilbao"}]},{id:"49438",title:"Perovskite Nanomaterials – Synthesis, Characterization, and Applications",slug:"perovskite-nanomaterials-synthesis-characterization-and-applications",totalDownloads:9186,totalCrossrefCites:24,totalDimensionsCites:57,abstract:"Inorganic perovskite-type oxides are fascinating nanomaterials for wide applications in catalysis, fuel cells, and electrochemical sensing. Perovskites prepared in the nanoscale have recently received extensive attention due to their catalytic nature when used as electrode modifiers. The catalytic activity of these oxides is higher than that of many transition metals compounds and even some precious metal oxides. They exhibit attractive physical and chemical characteristics such as electronic conductivity, electrically active structure, the oxide ions mobility through the crystal lattice, variations on the content of the oxygen, thermal and chemical stability, and supermagnetic, photocatalytic, thermoelectric, and dielectric properties.",book:{id:"5063",slug:"perovskite-materials-synthesis-characterisation-properties-and-applications",title:"Perovskite Materials",fullTitle:"Perovskite Materials - Synthesis, Characterisation, Properties, and Applications"},signatures:"Nada F. Atta, Ahmed Galal and Ekram H. El-Ads",authors:[{id:"30072",title:"Prof.",name:"Nada",middleName:null,surname:"F. Atta",slug:"nada-f.-atta",fullName:"Nada F. Atta"},{id:"174033",title:"Prof.",name:"Ahmed",middleName:null,surname:"Galal",slug:"ahmed-galal",fullName:"Ahmed Galal"},{id:"174034",title:"MSc.",name:"Ekram",middleName:null,surname:"El-Ads",slug:"ekram-el-ads",fullName:"Ekram El-Ads"},{id:"176164",title:"MSc.",name:"Ekram",middleName:null,surname:"Ekram H. El-Ads",slug:"ekram-ekram-h.-el-ads",fullName:"Ekram Ekram H. El-Ads"}]}],onlineFirstChaptersFilter:{topicId:"770",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:8,limit:8,total:0},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:108,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:33,numberOfPublishedChapters:330,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:14,numberOfPublishedChapters:145,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:9,numberOfPublishedChapters:140,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:123,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:112,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:22,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:11,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:"2753-6580",doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. The whole process of submitting an article and editing of the submitted article goes extremely smooth and fast, the number of reads and downloads of chapters is high, and the contributions are also frequently cited.",author:{id:"55578",name:"Antonio",surname:"Jurado-Navas",institutionString:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRisIQAS/Profile_Picture_1626166543950",slug:"antonio-jurado-navas",institution:{id:"720",name:"University of Malaga",country:{id:null,name:"Spain"}}}},{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}}]},series:{item:{id:"3",title:"Dentistry",doi:"10.5772/intechopen.71199",issn:"2631-6218",scope:"\r\n\tThis book series will offer a comprehensive overview of recent research trends as well as clinical applications within different specialties of dentistry. Topics will include overviews of the health of the oral cavity, from prevention and care to different treatments for the rehabilitation of problems that may affect the organs and/or tissues present. The different areas of dentistry will be explored, with the aim of disseminating knowledge and providing readers with new tools for the comprehensive treatment of their patients with greater safety and with current techniques. Ongoing issues, recent advances, and future diagnostic approaches and therapeutic strategies will also be discussed. This series of books will focus on various aspects of the properties and results obtained by the various treatments available, whether preventive or curative.
",coverUrl:"https://cdn.intechopen.com/series/covers/3.jpg",latestPublicationDate:"August 14th, 2022",hasOnlineFirst:!0,numberOfPublishedBooks:9,editor:{id:"419588",title:"Ph.D.",name:"Sergio",middleName:"Alexandre",surname:"Gehrke",slug:"sergio-gehrke",fullName:"Sergio Gehrke",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038WgMKQA0/Profile_Picture_2022-06-02T11:44:20.jpg",biography:"Dr. Sergio Alexandre Gehrke is a doctorate holder in two fields. The first is a Ph.D. in Cellular and Molecular Biology from the Pontificia Catholic University, Porto Alegre, Brazil, in 2010 and the other is an International Ph.D. in Bioengineering from the Universidad Miguel Hernandez, Elche/Alicante, Spain, obtained in 2020. In 2018, he completed a postdoctoral fellowship in Materials Engineering in the NUCLEMAT of the Pontificia Catholic University, Porto Alegre, Brazil. He is currently the Director of the Postgraduate Program in Implantology of the Bioface/UCAM/PgO (Montevideo, Uruguay), Director of the Cathedra of Biotechnology of the Catholic University of Murcia (Murcia, Spain), an Extraordinary Full Professor of the Catholic University of Murcia (Murcia, Spain) as well as the Director of the private center of research Biotecnos – Technology and Science (Montevideo, Uruguay). Applied biomaterials, cellular and molecular biology, and dental implants are among his research interests. He has published several original papers in renowned journals. In addition, he is also a Collaborating Professor in several Postgraduate programs at different universities all over the world.",institutionString:null,institution:{name:"Universidad Católica San Antonio de Murcia",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:2,paginationItems:[{id:"1",title:"Oral Health",coverUrl:"https://cdn.intechopen.com/series_topics/covers/1.jpg",isOpenForSubmission:!0,editor:{id:"173955",title:"Prof.",name:"Sandra",middleName:null,surname:"Marinho",slug:"sandra-marinho",fullName:"Sandra Marinho",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRGYMQA4/Profile_Picture_2022-06-01T13:22:41.png",biography:"Dr. Sandra A. Marinho is an Associate Professor and Brazilian researcher at the State University of Paraíba (Universidade Estadual da Paraíba- UEPB), Campus VIII, located in Araruna, state of Paraíba since 2011. She holds a degree in Dentistry from the Federal University of Alfenas (UNIFAL), while her specialization and professional improvement in Stomatology took place at Hospital Heliopolis (São Paulo, SP). Her qualifications are: a specialist in Dental Imaging and Radiology, Master in Dentistry (Periodontics) from the University of São Paulo (FORP-USP, Ribeirão Preto, SP), and Doctor (Ph.D.) in Dentistry (Stomatology Clinic) from Hospital São Lucas of the Pontifical Catholic University of Rio Grande do Sul (HSL-PUCRS, Porto Alegre, RS). She held a postdoctoral internship at the Federal University from Jequitinhonha and Mucuri Valleys (UFVJM, Diamantina, MG). She is currently a member of the Brazilian Society for Dental Research (SBPqO) and the Brazilian Society of Stomatology and Pathology (SOBEP). Dr. Marinho's experience in Dentistry mainly covers the following subjects: oral diagnosis, oral radiology; oral medicine; lesions and oral infections; oral pathology, laser therapy and epidemiological studies.",institutionString:null,institution:{name:"State University of Paraíba",institutionURL:null,country:{name:"Brazil"}}},editorTwo:null,editorThree:null},{id:"2",title:"Prosthodontics and Implant Dentistry",coverUrl:"https://cdn.intechopen.com/series_topics/covers/2.jpg",isOpenForSubmission:!0,editor:{id:"179568",title:"Associate Prof.",name:"Wen Lin",middleName:null,surname:"Chai",slug:"wen-lin-chai",fullName:"Wen Lin Chai",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRHGAQA4/Profile_Picture_2022-05-23T14:31:12.png",biography:"Professor Dr. Chai Wen Lin is currently a lecturer at the Department of Restorative Dentistry, Faculty of Dentistry of the University of Malaya. She obtained a Master of Dental Science in 2006 and a Ph.D. in 2011. Her Ph.D. research work on the soft tissue-implant interface at the University of Sheffield has yielded several important publications in the key implant journals. She was awarded an Excellent Exchange Award by the University of Sheffield which gave her the opportunity to work at the famous Faculty of Dentistry of the University of Gothenburg, Sweden, under the tutelage of Prof. Peter Thomsen. In 2016, she was appointed as a visiting scholar at UCLA, USA, with attachment in Hospital Dentistry, and involvement in research work related to zirconia implant. In 2016, her contribution to dentistry was recognized by the Royal College of Surgeon of Edinburgh with her being awarded a Fellowship in Dental Surgery. She has authored numerous papers published both in local and international journals. She was the Editor of the Malaysian Dental Journal for several years. Her main research interests are implant-soft tissue interface, zirconia implant, photofunctionalization, 3D-oral mucosal model and pulpal regeneration.",institutionString:null,institution:{name:"University of Malaya",institutionURL:null,country:{name:"Malaysia"}}},editorTwo:{id:"479686",title:"Dr.",name:"Ghee Seong",middleName:null,surname:"Lim",slug:"ghee-seong-lim",fullName:"Ghee Seong Lim",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003ScjLZQAZ/Profile_Picture_2022-06-08T14:17:06.png",biography:"Assoc. Prof Dr. Lim Ghee Seong graduated with a Bachelor of Dental Surgery from University of Malaya, Kuala Lumpur in 2008. He then pursued his Master in Clinical Dentistry, specializing in Restorative Dentistry at Newcastle University, Newcastle, UK, where he graduated with distinction. He has also been awarded the International Training Fellowship (Restorative Dentistry) from the Royal College of Surgeons. His passion for teaching then led him to join the faculty of dentistry at University Malaya and he has since became a valuable lecturer and clinical specialist in the Department of Restorative Dentistry. He is currently the removable prosthodontic undergraduate year 3 coordinator, head of the undergraduate module on occlusion and a member of the multidisciplinary team for the TMD clinic. He has previous membership in the British Society for Restorative Dentistry, the Malaysian Association of Aesthetic Dentistry and he is currently a lifetime member of the Malaysian Association for Prosthodontics. Currently, he is also the examiner for the Restorative Specialty Membership Examinations, Royal College of Surgeons, England. He has authored and co-authored handful of both local and international journal articles. His main interest is in prosthodontics, dental material, TMD and regenerative dentistry.",institutionString:null,institution:{name:"University of Malaya",institutionURL:null,country:{name:"Malaysia"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:49,paginationItems:[{id:"83087",title:"Role of Cellular Responses in Periodontal Tissue Destruction",doi:"10.5772/intechopen.106645",signatures:"Nam Cong-Nhat Huynh",slug:"role-of-cellular-responses-in-periodontal-tissue-destruction",totalDownloads:0,totalCrossrefCites:null,totalDimensionsCites:null,authors:null,book:{title:"Periodontology - New Insights",coverURL:"https://cdn.intechopen.com/books/images_new/11566.jpg",subseries:{id:"1",title:"Oral Health"}}},{id:"83073",title:"Dental and Orofacial Trauma Impacts on Oral-Health-Related—Quality of Life in Children: Low- and Middle-Income Countries",doi:"10.5772/intechopen.105845",signatures:"Yolanda Malele-Kolisa, Nazia Khan, Mpho P. Molete, Maphefo D. Thekiso and Mzubanzi Mabongo",slug:"dental-and-orofacial-trauma-impacts-on-oral-health-related-quality-of-life-in-children-low-and-middl",totalDownloads:2,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Trauma",coverURL:"https://cdn.intechopen.com/books/images_new/11567.jpg",subseries:{id:"2",title:"Prosthodontics and Implant Dentistry"}}},{id:"82938",title:"Trauma from Occlusion: Practical Management Guidelines",doi:"10.5772/intechopen.105960",signatures:"Prashanth Shetty, Shweta Hegde, Shubham Chelkar, Rahul Chaturvedi, Shruti Pochhi, Aakanksha Shrivastava, Dudala Lakshmi, Shreya Mukherjee, Pankaj Bajaj and Shahzada Asif Raza",slug:"trauma-from-occlusion-practical-management-guidelines",totalDownloads:13,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Trauma",coverURL:"https://cdn.intechopen.com/books/images_new/11567.jpg",subseries:{id:"2",title:"Prosthodontics and Implant Dentistry"}}},{id:"82654",title:"Atraumatic Restorative Treatment: More than a Minimally Invasive Approach?",doi:"10.5772/intechopen.105623",signatures:"Manal A. Ablal",slug:"atraumatic-restorative-treatment-more-than-a-minimally-invasive-approach",totalDownloads:4,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Dental Caries - The Selection of Restoration Methods and Restorative Materials",coverURL:"https://cdn.intechopen.com/books/images_new/11565.jpg",subseries:{id:"1",title:"Oral Health"}}}]},overviewPagePublishedBooks:{paginationCount:9,paginationItems:[{type:"book",id:"6668",title:"Dental Caries",subtitle:"Diagnosis, Prevention and Management",coverURL:"https://cdn.intechopen.com/books/images_new/6668.jpg",slug:"dental-caries-diagnosis-prevention-and-management",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Zühre Akarslan",hash:"b0f7667770a391f772726c3013c1b9ba",volumeInSeries:1,fullTitle:"Dental Caries - Diagnosis, Prevention and Management",editors:[{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",institutionURL:null,country:{name:"Turkey"}}}]},{type:"book",id:"7139",title:"Current Approaches in Orthodontics",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7139.jpg",slug:"current-approaches-in-orthodontics",publishedDate:"April 10th 2019",editedByType:"Edited by",bookSignature:"Belma Işık Aslan and Fatma Deniz Uzuner",hash:"2c77384eeb748cf05a898d65b9dcb48a",volumeInSeries:2,fullTitle:"Current Approaches in Orthodontics",editors:[{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null}]},{type:"book",id:"7572",title:"Trauma in Dentistry",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7572.jpg",slug:"trauma-in-dentistry",publishedDate:"July 3rd 2019",editedByType:"Edited by",bookSignature:"Serdar Gözler",hash:"7cb94732cfb315f8d1e70ebf500eb8a9",volumeInSeries:3,fullTitle:"Trauma in Dentistry",editors:[{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",institutionURL:null,country:{name:"Turkey"}}}]},{type:"book",id:"7060",title:"Gingival Disease",subtitle:"A Professional Approach for Treatment and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/7060.jpg",slug:"gingival-disease-a-professional-approach-for-treatment-and-prevention",publishedDate:"October 23rd 2019",editedByType:"Edited by",bookSignature:"Alaa Eddin Omar Al Ostwani",hash:"b81d39988cba3a3cf746c1616912cf41",volumeInSeries:4,fullTitle:"Gingival Disease - A Professional Approach for Treatment and Prevention",editors:[{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",institutionURL:null,country:{name:"India"}}}]}]},openForSubmissionBooks:{paginationCount:2,paginationItems:[{id:"11673",title:"Stem Cell Research",coverURL:"https://cdn.intechopen.com/books/images_new/11673.jpg",hash:"13092df328080c762dd9157be18ca38c",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 13th 2022",isOpenForSubmission:!0,editors:[{id:"203598",title:"Ph.D.",name:"Diana",surname:"Kitala",slug:"diana-kitala",fullName:"Diana Kitala"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{id:"12215",title:"Cell Death and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/12215.jpg",hash:"dfd456a29478fccf4ebd3294137eb1e3",secondStepPassed:!0,currentStepOfPublishingProcess:3,submissionDeadline:"July 29th 2022",isOpenForSubmission:!0,editors:[{id:"59529",title:"Dr.",name:"Ke",surname:"Xu",slug:"ke-xu",fullName:"Ke Xu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},onlineFirstChapters:{paginationCount:42,paginationItems:[{id:"82914",title:"Glance on the Critical Role of IL-23 Receptor Gene Variations in Inflammation-Induced Carcinogenesis",doi:"10.5772/intechopen.105049",signatures:"Mohammed El-Gedamy",slug:"glance-on-the-critical-role-of-il-23-receptor-gene-variations-in-inflammation-induced-carcinogenesis",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Chemokines Updates",coverURL:"https://cdn.intechopen.com/books/images_new/11672.jpg",subseries:{id:"18",title:"Proteomics"}}},{id:"82875",title:"Lipidomics as a Tool in the Diagnosis and Clinical Therapy",doi:"10.5772/intechopen.105857",signatures:"María Elizbeth Alvarez Sánchez, Erick Nolasco Ontiveros, Rodrigo Arreola, Adriana Montserrat Espinosa González, Ana María García Bores, Roberto Eduardo López Urrutia, Ignacio Peñalosa Castro, María del Socorro Sánchez Correa and Edgar Antonio Estrella Parra",slug:"lipidomics-as-a-tool-in-the-diagnosis-and-clinical-therapy",totalDownloads:7,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82440",title:"Lipid Metabolism and Associated Molecular Signaling Events in Autoimmune Disease",doi:"10.5772/intechopen.105746",signatures:"Mohan Vanditha, Sonu Das and Mathew John",slug:"lipid-metabolism-and-associated-molecular-signaling-events-in-autoimmune-disease",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82483",title:"Oxidative Stress in Cardiovascular Diseases",doi:"10.5772/intechopen.105891",signatures:"Laura Mourino-Alvarez, Tamara Sastre-Oliva, Nerea Corbacho-Alonso and Maria G. Barderas",slug:"oxidative-stress-in-cardiovascular-diseases",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Importance of Oxidative Stress and Antioxidant System in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11671.jpg",subseries:{id:"15",title:"Chemical Biology"}}},{id:"82751",title:"Mitochondria-Endoplasmic Reticulum Interaction in Central Neurons",doi:"10.5772/intechopen.105738",signatures:"Liliya Kushnireva and Eduard Korkotian",slug:"mitochondria-endoplasmic-reticulum-interaction-in-central-neurons",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82709",title:"Fatty Acid Metabolism as a Tumor Marker",doi:"10.5772/intechopen.106072",signatures:"Gatot Nyarumenteng Adhipurnawan Winarno",slug:"fatty-acid-metabolism-as-a-tumor-marker",totalDownloads:10,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Fatty Acids - Recent Advances",coverURL:"https://cdn.intechopen.com/books/images_new/11669.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82716",title:"Advanced glycation end product induced endothelial dysfunction through ER stress: Unravelling the role of Paraoxonase 2",doi:"10.5772/intechopen.106018",signatures:"Ramya Ravi and Bharathidevi Subramaniam Rajesh",slug:"advanced-glycation-end-product-induced-endothelial-dysfunction-through-er-stress-unravelling-the-rol",totalDownloads:13,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82388",title:"Epigenetics: Science of Changes without Change in DNA Sequences",doi:"10.5772/intechopen.105039",signatures:"Jayisha Dhargawe, Rita Lakkakul and Pradip Hirapure",slug:"epigenetics-science-of-changes-without-change-in-dna-sequences",totalDownloads:17,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Modifications of Biomolecules",coverURL:"https://cdn.intechopen.com/books/images_new/11098.jpg",subseries:null}},{id:"82583",title:"Leukaemia: The Purinergic System and Small Extracellular Vesicles",doi:"10.5772/intechopen.104326",signatures:"Arinzechukwu Ude and Kelechi Okeke",slug:"leukaemia-the-purinergic-system-and-small-extracellular-vesicles",totalDownloads:11,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82531",title:"Abnormal Iron Metabolism and Its Effect on Dentistry",doi:"10.5772/intechopen.104502",signatures:"Chinmayee Dahihandekar and Sweta Kale Pisulkar",slug:"abnormal-iron-metabolism-and-its-effect-on-dentistry",totalDownloads:12,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Iron Metabolism - A Double-Edged Sword",coverURL:"https://cdn.intechopen.com/books/images_new/10842.jpg",subseries:{id:"17",title:"Metabolism"}}}]},subseriesFiltersForOFChapters:[{caption:"Chemical Biology",value:15,count:2,group:"subseries"},{caption:"Proteomics",value:18,count:2,group:"subseries"},{caption:"Cell and Molecular Biology",value:14,count:17,group:"subseries"},{caption:"Metabolism",value:17,count:18,group:"subseries"}],publishedBooks:{paginationCount:9,paginationItems:[{type:"book",id:"10808",title:"Current Concepts in Dental Implantology",subtitle:"From Science to Clinical Research",coverURL:"https://cdn.intechopen.com/books/images_new/10808.jpg",slug:"current-concepts-in-dental-implantology-from-science-to-clinical-research",publishedDate:"July 27th 2022",editedByType:"Edited by",bookSignature:"Dragana Gabrić and Marko Vuletić",hash:"4af8830e463f89c57515c2da2b9777b0",volumeInSeries:11,fullTitle:"Current Concepts in Dental Implantology - From Science to Clinical Research",editors:[{id:"26946",title:"Prof.",name:"Dragana",middleName:null,surname:"Gabrić",slug:"dragana-gabric",fullName:"Dragana Gabrić",profilePictureURL:"https://mts.intechopen.com/storage/users/26946/images/system/26946.png",institutionString:"University of Zagreb",institution:{name:"University of Zagreb",institutionURL:null,country:{name:"Croatia"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9493",title:"Periodontology",subtitle:"Fundamentals and Clinical Features",coverURL:"https://cdn.intechopen.com/books/images_new/9493.jpg",slug:"periodontology-fundamentals-and-clinical-features",publishedDate:"February 16th 2022",editedByType:"Edited by",bookSignature:"Petra Surlin",hash:"dfe986c764d6c82ae820c2df5843a866",volumeInSeries:8,fullTitle:"Periodontology - Fundamentals and Clinical Features",editors:[{id:"171921",title:"Prof.",name:"Petra",middleName:null,surname:"Surlin",slug:"petra-surlin",fullName:"Petra Surlin",profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",institutionString:"University of Medicine and Pharmacy of Craiova",institution:{name:"University of Medicine and Pharmacy of Craiova",institutionURL:null,country:{name:"Romania"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"9588",title:"Clinical Concepts and Practical Management Techniques in Dentistry",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/9588.jpg",slug:"clinical-concepts-and-practical-management-techniques-in-dentistry",publishedDate:"February 9th 2022",editedByType:"Edited by",bookSignature:"Aneesa Moolla",hash:"42deab8d3bcf3edf64d1d9028d42efd1",volumeInSeries:7,fullTitle:"Clinical Concepts and Practical Management Techniques in Dentistry",editors:[{id:"318170",title:"Dr.",name:"Aneesa",middleName:null,surname:"Moolla",slug:"aneesa-moolla",fullName:"Aneesa Moolla",profilePictureURL:"https://mts.intechopen.com/storage/users/318170/images/system/318170.png",institutionString:"University of the Witwatersrand",institution:{name:"University of the Witwatersrand",institutionURL:null,country:{name:"South Africa"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8202",title:"Periodontal Disease",subtitle:"Diagnostic and Adjunctive Non-surgical Considerations",coverURL:"https://cdn.intechopen.com/books/images_new/8202.jpg",slug:"periodontal-disease-diagnostic-and-adjunctive-non-surgical-considerations",publishedDate:"February 5th 2020",editedByType:"Edited by",bookSignature:"Nermin Mohammed Ahmed Yussif",hash:"0aee9799da7db2c732be44dd8fed16d8",volumeInSeries:6,fullTitle:"Periodontal Disease - Diagnostic and Adjunctive Non-surgical Considerations",editors:[{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",institutionString:"MSA University",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"8837",title:"Human Teeth",subtitle:"Key Skills and Clinical Illustrations",coverURL:"https://cdn.intechopen.com/books/images_new/8837.jpg",slug:"human-teeth-key-skills-and-clinical-illustrations",publishedDate:"January 22nd 2020",editedByType:"Edited by",bookSignature:"Zühre Akarslan and Farid Bourzgui",hash:"ac055c5801032970123e0a196c2e1d32",volumeInSeries:5,fullTitle:"Human Teeth - Key Skills and Clinical Illustrations",editors:[{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",institutionString:"Gazi University",institution:{name:"Gazi University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:{id:"52177",title:"Prof.",name:"Farid",middleName:null,surname:"Bourzgui",slug:"farid-bourzgui",fullName:"Farid Bourzgui",profilePictureURL:"https://mts.intechopen.com/storage/users/52177/images/system/52177.png",biography:"Prof. Farid Bourzgui obtained his DMD and his DNSO option in Orthodontics at the School of Dental Medicine, Casablanca Hassan II University, Morocco, in 1995 and 2000, respectively. Currently, he is a professor of Orthodontics. He holds a Certificate of Advanced Study type A in Technology of Biomaterials used in Dentistry (1995); Certificate of Advanced Study type B in Dento-Facial Orthopaedics (1997) from the Faculty of Dental Surgery, University Denis Diderot-Paris VII, France; Diploma of Advanced Study (DESA) in Biocompatibility of Biomaterials from the Faculty of Medicine and Pharmacy of Casablanca (2002); Certificate of Clinical Occlusodontics from the Faculty of Dentistry of Casablanca (2004); University Diploma of Biostatistics and Perceptual Health Measurement from the Faculty of Medicine and Pharmacy of Casablanca (2011); and a University Diploma of Pedagogy of Odontological Sciences from the Faculty of Dentistry of Casablanca (2013). He is the author of several scientific articles, book chapters, and books.",institutionString:"University of Hassan II Casablanca",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"7",totalChapterViews:"0",totalEditedBooks:"2",institution:{name:"University of Hassan II Casablanca",institutionURL:null,country:{name:"Morocco"}}},equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7060",title:"Gingival Disease",subtitle:"A Professional Approach for Treatment and Prevention",coverURL:"https://cdn.intechopen.com/books/images_new/7060.jpg",slug:"gingival-disease-a-professional-approach-for-treatment-and-prevention",publishedDate:"October 23rd 2019",editedByType:"Edited by",bookSignature:"Alaa Eddin Omar Al Ostwani",hash:"b81d39988cba3a3cf746c1616912cf41",volumeInSeries:4,fullTitle:"Gingival Disease - A Professional Approach for Treatment and Prevention",editors:[{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",institutionURL:null,country:{name:"India"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7572",title:"Trauma in Dentistry",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7572.jpg",slug:"trauma-in-dentistry",publishedDate:"July 3rd 2019",editedByType:"Edited by",bookSignature:"Serdar Gözler",hash:"7cb94732cfb315f8d1e70ebf500eb8a9",volumeInSeries:3,fullTitle:"Trauma in Dentistry",editors:[{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"7139",title:"Current Approaches in Orthodontics",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7139.jpg",slug:"current-approaches-in-orthodontics",publishedDate:"April 10th 2019",editedByType:"Edited by",bookSignature:"Belma Işık Aslan and Fatma Deniz Uzuner",hash:"2c77384eeb748cf05a898d65b9dcb48a",volumeInSeries:2,fullTitle:"Current Approaches in Orthodontics",editors:[{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null},{type:"book",id:"6668",title:"Dental Caries",subtitle:"Diagnosis, Prevention and Management",coverURL:"https://cdn.intechopen.com/books/images_new/6668.jpg",slug:"dental-caries-diagnosis-prevention-and-management",publishedDate:"September 19th 2018",editedByType:"Edited by",bookSignature:"Zühre Akarslan",hash:"b0f7667770a391f772726c3013c1b9ba",volumeInSeries:1,fullTitle:"Dental Caries - Diagnosis, Prevention and Management",editors:[{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",institutionString:"Gazi University",institution:{name:"Gazi University",institutionURL:null,country:{name:"Turkey"}}}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null}]},subseriesFiltersForPublishedBooks:[{group:"subseries",caption:"Prosthodontics and Implant Dentistry",value:2,count:3},{group:"subseries",caption:"Oral Health",value:1,count:6}],publicationYearFilters:[{group:"publicationYear",caption:"2022",value:2022,count:3},{group:"publicationYear",caption:"2020",value:2020,count:2},{group:"publicationYear",caption:"2019",value:2019,count:3},{group:"publicationYear",caption:"2018",value:2018,count:1}],authors:{paginationCount:245,paginationItems:[{id:"196707",title:"Prof.",name:"Mustafa Numan",middleName:null,surname:"Bucak",slug:"mustafa-numan-bucak",fullName:"Mustafa Numan Bucak",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/196707/images/system/196707.png",biography:"Mustafa Numan Bucak received a bachelor’s degree from the Veterinary Faculty, Ankara University, Turkey, where he also obtained a Ph.D. in Sperm Cryobiology. He is an academic staff member of the Department of Reproduction and Artificial Insemination, Selçuk University, Turkey. He manages several studies on sperms and embryos and is an editorial board member for several international journals. His studies include sperm cryobiology, in vitro fertilization, and embryo production in animals.",institutionString:"Selçuk University, Faculty of Veterinary Medicine",institution:null},{id:"90846",title:"Prof.",name:"Yusuf",middleName:null,surname:"Bozkurt",slug:"yusuf-bozkurt",fullName:"Yusuf Bozkurt",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/90846/images/system/90846.jpg",biography:"Yusuf Bozkurt has a BSc, MSc, and Ph.D. from Ankara University, Turkey. He is currently a Professor of Biotechnology of Reproduction in the field of Aquaculture, İskenderun Technical University, Turkey. His research interests include reproductive biology and biotechnology with an emphasis on cryo-conservation. He is on the editorial board of several international peer-reviewed journals and has published many papers. Additionally, he has participated in many international and national congresses, seminars, and workshops with oral and poster presentations. He is an active member of many local and international organizations.",institutionString:"İskenderun Technical University",institution:{name:"İskenderun Technical University",country:{name:"Turkey"}}},{id:"61139",title:"Dr.",name:"Sergey",middleName:null,surname:"Tkachev",slug:"sergey-tkachev",fullName:"Sergey Tkachev",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/61139/images/system/61139.png",biography:"Dr. Sergey Tkachev is a senior research scientist at the Institute of Fundamental Medicine and Biology, Kazan Federal University, Russia, and at the Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia. He received his Ph.D. in Molecular Biology with his thesis “Genetic variability of the tick-borne encephalitis virus in natural foci of Novosibirsk city and its suburbs.” His primary field is molecular virology with research emphasis on vector-borne viruses, especially tick-borne encephalitis virus, Kemerovo virus and Omsk hemorrhagic fever virus, rabies virus, molecular genetics, biology, and epidemiology of virus pathogens.",institutionString:"Russian Academy of Sciences",institution:{name:"Russian Academy of Sciences",country:{name:"Russia"}}},{id:"310962",title:"Dr.",name:"Amlan",middleName:"Kumar",surname:"Patra",slug:"amlan-patra",fullName:"Amlan Patra",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/310962/images/system/310962.jpg",biography:"Amlan K. Patra, FRSB, obtained a Ph.D. in Animal Nutrition from Indian Veterinary Research Institute, India, in 2002. He is currently an associate professor at West Bengal University of Animal and Fishery Sciences. He has more than twenty years of research and teaching experience. He held previous positions at the American Institute for Goat Research, The Ohio State University, Columbus, USA, and Free University of Berlin, Germany. His research focuses on animal nutrition, particularly ruminants and poultry nutrition, gastrointestinal electrophysiology, meta-analysis and modeling in nutrition, and livestock–environment interaction. He has authored around 175 articles in journals, book chapters, and proceedings. Dr. Patra serves on the editorial boards of several reputed journals.",institutionString:null,institution:{name:"West Bengal University of Animal and Fishery Sciences",country:{name:"India"}}},{id:"53998",title:"Prof.",name:"László",middleName:null,surname:"Babinszky",slug:"laszlo-babinszky",fullName:"László Babinszky",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/53998/images/system/53998.png",biography:"László Babinszky is Professor Emeritus, Department of Animal Nutrition Physiology, University of Debrecen, Hungary. He has also worked in the Department of Animal Nutrition, University of Wageningen, Netherlands; the Institute for Livestock Feeding and Nutrition (IVVO), Lelystad, Netherlands; the Agricultural University of Vienna (BOKU); the Institute for Animal Breeding and Nutrition, Austria; and the Oscar Kellner Research Institute for Animal Nutrition, Rostock, Germany. In 1992, Dr. Babinszky obtained a Ph.D. in Animal Nutrition from the University of Wageningen. His main research areas are swine and poultry nutrition. He has authored more than 300 publications (papers, book chapters) and edited four books and fourteen international conference proceedings.",institutionString:"University of Debrecen",institution:{name:"University of Debrecen",country:{name:"Hungary"}}},{id:"201830",title:"Dr.",name:"Fernando",middleName:"Sanchez",surname:"Davila",slug:"fernando-davila",fullName:"Fernando Davila",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/201830/images/5017_n.jpg",biography:"I am a professor at UANL since 1988. My research lines are the development of reproductive techniques in small ruminants. We also conducted research on sexual and social behavior in males.\nI am Mexican and study my professional career as an engineer in agriculture and animal science at UANL. Then take a masters degree in science in Germany (Animal breeding). Take a doctorate in animal science at the UANL.",institutionString:null,institution:{name:"Universidad Autónoma de Nuevo León",country:{name:"Mexico"}}},{id:"309250",title:"Dr.",name:"Miguel",middleName:null,surname:"Quaresma",slug:"miguel-quaresma",fullName:"Miguel Quaresma",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/309250/images/9059_n.jpg",biography:"Miguel Nuno Pinheiro Quaresma was born on May 26, 1974 in Dili, Timor Island. He is married with two children: a boy and a girl, and he is a resident in Vila Real, Portugal. He graduated in Veterinary Medicine in August 1998 and obtained his Ph.D. degree in Veterinary Sciences -Clinical Area in February 2015, both from the University of Trás-os-Montes e Alto Douro. He is currently enrolled in the Alternative Residency of the European College of Animal Reproduction. He works as a Senior Clinician at the Veterinary Teaching Hospital of UTAD (HVUTAD) with a role in clinical activity in the area of livestock and equine species as well as to support teaching and research in related areas. He teaches as an Invited Professor in Reproduction Medicine I and II of the Master\\'s in Veterinary Medicine degree at UTAD. Currently, he holds the position of Chairman of the Portuguese Buiatrics Association. He is a member of the Consultive Group on Production Animals of the OMV. He has 19 publications in indexed international journals (ISIS), as well as over 60 publications and oral presentations in both Portuguese and international journals and congresses.",institutionString:"University of Trás-os-Montes and Alto Douro",institution:{name:"University of Trás-os-Montes and Alto Douro",country:{name:"Portugal"}}},{id:"38652",title:"Prof.",name:"Rita",middleName:null,surname:"Payan-Carreira",slug:"rita-payan-carreira",fullName:"Rita Payan-Carreira",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRiFPQA0/Profile_Picture_1614601496313",biography:"Rita Payan Carreira earned her Veterinary Degree from the Faculty of Veterinary Medicine in Lisbon, Portugal, in 1985. She obtained her Ph.D. in Veterinary Sciences from the University of Trás-os-Montes e Alto Douro, Portugal. After almost 32 years of teaching at the University of Trás-os-Montes and Alto Douro, she recently moved to the University of Évora, Department of Veterinary Medicine, where she teaches in the field of Animal Reproduction and Clinics. Her primary research areas include the molecular markers of the endometrial cycle and the embryo–maternal interaction, including oxidative stress and the reproductive physiology and disorders of sexual development, besides the molecular determinants of male and female fertility. She often supervises students preparing their master's or doctoral theses. She is also a frequent referee for various journals.",institutionString:null,institution:{name:"University of Évora",country:{name:"Portugal"}}},{id:"283019",title:"Dr.",name:"Oudessa",middleName:null,surname:"Kerro Dego",slug:"oudessa-kerro-dego",fullName:"Oudessa Kerro Dego",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/283019/images/system/283019.png",biography:"Dr. Kerro Dego is a veterinary microbiologist with training in veterinary medicine, microbiology, and anatomic pathology. Dr. Kerro Dego is an assistant professor of dairy health in the department of animal science, the University of Tennessee, Institute of Agriculture, Knoxville, Tennessee. He received his D.V.M. (1997), M.S. (2002), and Ph.D. (2008) degrees in Veterinary Medicine, Animal Pathology and Veterinary Microbiology from College of Veterinary Medicine, Addis Ababa University, Ethiopia; College of Veterinary Medicine, Utrecht University, the Netherlands and Western College of Veterinary Medicine, University of Saskatchewan, Canada respectively. He did his Postdoctoral training in microbial pathogenesis (2009 - 2015) in the Department of Animal Science, the University of Tennessee, Institute of Agriculture, Knoxville, Tennessee. Dr. Kerro Dego’s research focuses on the prevention and control of infectious diseases of farm animals, particularly mastitis, improving dairy food safety, and mitigation of antimicrobial resistance. Dr. Kerro Dego has extensive experience in studying the pathogenesis of bacterial infections, identification of virulence factors, and vaccine development and efficacy testing against major bacterial mastitis pathogens. Dr. Kerro Dego conducted numerous controlled experimental and field vaccine efficacy studies, vaccination, and evaluation of immunological responses in several species of animals, including rodents (mice) and large animals (bovine and ovine).",institutionString:"University of Tennessee at Knoxville",institution:{name:"University of Tennessee at Knoxville",country:{name:"United States of America"}}},{id:"251314",title:"Dr.",name:"Juan Carlos",middleName:null,surname:"Gardón Poggi",slug:"juan-carlos-gardon-poggi",fullName:"Juan Carlos Gardón Poggi",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/251314/images/system/251314.jpeg",biography:"Juan Carlos Gardón Poggi received University degree from the Faculty of Agrarian Science in Argentina, in 1983. Also he received Masters Degree and PhD from Córdoba University, Spain. He is currently a Professor at the Catholic University of Valencia San Vicente Mártir, at the Department of Medicine and Animal Surgery. He teaches diverse courses in the field of Animal Reproduction and he is the Director of the Veterinary Farm. He also participates in academic postgraduate activities at the Veterinary Faculty of Murcia University, Spain. His research areas include animal physiology, physiology and biotechnology of reproduction either in males or females, the study of gametes under in vitro conditions and the use of ultrasound as a complement to physiological studies and development of applied biotechnologies. Routinely, he supervises students preparing their doctoral, master thesis or final degree projects.",institutionString:null,institution:{name:"Valencia Catholic University Saint Vincent Martyr",country:{name:"Spain"}}},{id:"309529",title:"Dr.",name:"Albert",middleName:null,surname:"Rizvanov",slug:"albert-rizvanov",fullName:"Albert Rizvanov",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/309529/images/9189_n.jpg",biography:'Albert A. Rizvanov is a Professor and Director of the Center for Precision and Regenerative Medicine at the Institute of Fundamental Medicine and Biology, Kazan Federal University (KFU), Russia. He is the Head of the Center of Excellence “Regenerative Medicine” and Vice-Director of Strategic Academic Unit \\"Translational 7P Medicine\\". Albert completed his Ph.D. at the University of Nevada, Reno, USA and Dr.Sci. at KFU. He is a corresponding member of the Tatarstan Academy of Sciences, Russian Federation. Albert is an author of more than 300 peer-reviewed journal articles and 22 patents. He has supervised 11 Ph.D. and 2 Dr.Sci. dissertations. Albert is the Head of the Dissertation Committee on Biochemistry, Microbiology, and Genetics at KFU.\nORCID https://orcid.org/0000-0002-9427-5739\nWebsite https://kpfu.ru/Albert.Rizvanov?p_lang=2',institutionString:"Kazan Federal University",institution:{name:"Kazan Federal University",country:{name:"Russia"}}},{id:"210551",title:"Dr.",name:"Arbab",middleName:null,surname:"Sikandar",slug:"arbab-sikandar",fullName:"Arbab Sikandar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210551/images/system/210551.jpg",biography:"Dr. Arbab Sikandar, PhD, M. Phil, DVM was born on April 05, 1981. He is currently working at the College of Veterinary & Animal Sciences as an Assistant Professor. He previously worked as a lecturer at the same University. \nHe is a Member/Secretory of Ethics committee (No. CVAS-9377 dated 18-04-18), Member of the QEC committee CVAS, Jhang (Regr/Gen/69/873, dated 26-10-2017), Member, Board of studies of Department of Basic Sciences (No. CVAS. 2851 Dated. 12-04-13, and No. CVAS, 9024 dated 20/11/17), Member of Academic Committee, CVAS, Jhang (No. CVAS/2004, Dated, 25-08-12), Member of the technical committee (No. CVAS/ 4085, dated 20,03, 2010 till 2016).\n\nDr. Arbab Sikandar contributed in five days hands-on-training on Histopathology at the Department of Pathology, UVAS from 12-16 June 2017. He received a Certificate of appreciation for contributions for Popularization of Science and Technology in the Society on 17-11-15. He was the resource person in the lecture series- ‘scientific writing’ at the Department of Anatomy and Histology, UVAS, Lahore on 29th October 2015. He won a full fellowship as a principal candidate for the year 2015 in the field of Agriculture, EICA, Egypt with ref. to the Notification No. 12(11) ACS/Egypt/2014 from 10 July 2015 to 25th September 2015.; he received a grant of Rs. 55000/- as research incentives from Director, Advanced Studies and Research, UVAS, Lahore upon publications of research papers in IF Journals (DR/215, dated 19-5-2014.. He obtained his PhD by winning a HEC Pakistan indigenous Scholarship, ‘Ph.D. fellowship for 5000 scholars – Phase II’ (2av1-147), 17-6/HEC/HRD/IS-II/12, November 15, 2012. \n\nDr. Sikandar is a member of numerous societies: Registered Veterinary Medical Practitioner (life member) and Registered Veterinary Medical Faculty of Pakistan Veterinary Medical Council. The Registration code of PVMC is RVMP/4298 and RVMF/ 0102.; Life member of the University of Veterinary and Animal Sciences, Lahore, Alumni Association with S# 664, dated: 6-4-12. ; Member 'Vets Care Organization Pakistan” with Reference No. VCO-605-149, dated 05-04-06. :Member 'Vet Crescent” (Society of Animal Health and Production), UVAS, Lahore.",institutionString:"University of Veterinary & Animal Science",institution:{name:"University of Veterinary and Animal Sciences",country:{name:"Pakistan"}}},{id:"311663",title:"Dr.",name:"Prasanna",middleName:null,surname:"Pal",slug:"prasanna-pal",fullName:"Prasanna Pal",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/311663/images/13261_n.jpg",biography:null,institutionString:null,institution:{name:"National Dairy Research Institute",country:{name:"India"}}},{id:"202192",title:"Dr.",name:"Catrin",middleName:null,surname:"Rutland",slug:"catrin-rutland",fullName:"Catrin Rutland",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202192/images/system/202192.png",biography:"Catrin Rutland is an Associate Professor of Anatomy and Developmental Genetics at the University of Nottingham, UK. She obtained a BSc from the University of Derby, England, a master’s degree from Technische Universität München, Germany, and a Ph.D. from the University of Nottingham. She undertook a post-doctoral research fellowship in the School of Medicine before accepting tenure in Veterinary Medicine and Science. Dr. Rutland also obtained an MMedSci (Medical Education) and a Postgraduate Certificate in Higher Education (PGCHE). She is the author of more than sixty peer-reviewed journal articles, twelve books/book chapters, and more than 100 research abstracts in cardiovascular biology and oncology. She is a board member of the European Association of Veterinary Anatomists, Fellow of the Anatomical Society, and Senior Fellow of the Higher Education Academy. Dr. Rutland has also written popular science books for the public. https://orcid.org/0000-0002-2009-4898. www.nottingham.ac.uk/vet/people/catrin.rutland",institutionString:null,institution:{name:"University of Nottingham",country:{name:"United Kingdom"}}},{id:"283315",title:"Prof.",name:"Samir",middleName:null,surname:"El-Gendy",slug:"samir-el-gendy",fullName:"Samir El-Gendy",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bRduYQAS/Profile_Picture_1606215849748",biography:"Samir El-Gendy is a Professor of anatomy and embryology at the faculty of veterinary medicine, Alexandria University, Egypt. Samir obtained his PhD in veterinary science in 2007 from the faculty of veterinary medicine, Alexandria University and has been a professor since 2017. Samir is an author on 24 articles at Scopus and 12 articles within local journals and 2 books/book chapters. His research focuses on applied anatomy, imaging techniques and computed tomography. Samir worked as a member of different local projects on E-learning and he is a board member of the African Association of Veterinary Anatomists and of anatomy societies and as an associated author at local and international journals. Orcid: https://orcid.org/0000-0002-6180-389X",institutionString:null,institution:{name:"Alexandria University",country:{name:"Egypt"}}},{id:"246149",title:"Dr.",name:"Valentina",middleName:null,surname:"Kubale",slug:"valentina-kubale",fullName:"Valentina Kubale",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/246149/images/system/246149.jpg",biography:"Valentina Kubale is Associate Professor of Veterinary Medicine at the Veterinary Faculty, University of Ljubljana, Slovenia. Since graduating from the Veterinary faculty she obtained her PhD in 2007, performed collaboration with the Department of Pharmacology, University of Copenhagen, Denmark. She continued as a post-doctoral fellow at the University of Copenhagen with a Lundbeck foundation fellowship. She is the editor of three books and author/coauthor of 23 articles in peer-reviewed scientific journals, 16 book chapters, and 68 communications at scientific congresses. Since 2008 she has been the Editor Assistant for the Slovenian Veterinary Research journal. She is a member of Slovenian Biochemical Society, The Endocrine Society, European Association of Veterinary Anatomists and Society for Laboratory Animals, where she is board member.",institutionString:"University of Ljubljana",institution:{name:"University of Ljubljana",country:{name:"Slovenia"}}},{id:"258334",title:"Dr.",name:"Carlos Eduardo",middleName:null,surname:"Fonseca-Alves",slug:"carlos-eduardo-fonseca-alves",fullName:"Carlos Eduardo Fonseca-Alves",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/258334/images/system/258334.jpg",biography:"Dr. Fonseca-Alves earned his DVM from Federal University of Goias – UFG in 2008. He completed an internship in small animal internal medicine at UPIS university in 2011, earned his MSc in 2013 and PhD in 2015 both in Veterinary Medicine at Sao Paulo State University – UNESP. Dr. Fonseca-Alves currently serves as an Assistant Professor at Paulista University – UNIP teaching small animal internal medicine.",institutionString:null,institution:{name:"Universidade Paulista",country:{name:"Brazil"}}},{id:"245306",title:"Dr.",name:"María Luz",middleName:null,surname:"Garcia Pardo",slug:"maria-luz-garcia-pardo",fullName:"María Luz Garcia Pardo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/245306/images/system/245306.png",biography:"María de la Luz García Pardo is an agricultural engineer from Universitat Politècnica de València, Spain. She has a Ph.D. in Animal Genetics. Currently, she is a lecturer at the Agrofood Technology Department of Miguel Hernández University, Spain. Her research is focused on genetics and reproduction in rabbits. The major goal of her research is the genetics of litter size through novel methods such as selection by the environmental sensibility of litter size, with forays into the field of animal welfare by analysing the impact on the susceptibility to diseases and stress of the does. Details of her publications can be found at https://orcid.org/0000-0001-9504-8290.",institutionString:null,institution:{name:"Miguel Hernandez University",country:{name:"Spain"}}},{id:"350704",title:"M.Sc.",name:"Camila",middleName:"Silva Costa",surname:"Ferreira",slug:"camila-ferreira",fullName:"Camila Ferreira",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/350704/images/17280_n.jpg",biography:"Graduated in Veterinary Medicine at the Fluminense Federal University, specialist in Equine Reproduction at the Brazilian Veterinary Institute (IBVET) and Master in Clinical Veterinary Medicine and Animal Reproduction at the Fluminense Federal University. She has experience in analyzing zootechnical indices in dairy cattle and organizing events related to Veterinary Medicine through extension grants. I have experience in the field of diagnostic imaging and animal reproduction in veterinary medicine through monitoring and scientific initiation scholarships. I worked at the Equus Central Reproduction Equine located in Santo Antônio de Jesus – BA in the 2016/2017 breeding season. I am currently a doctoral student with a scholarship from CAPES of the Postgraduate Program in Veterinary Medicine (Pathology and Clinical Sciences) at the Federal Rural University of Rio de Janeiro (UFRRJ) with a research project with an emphasis on equine endometritis.",institutionString:null,institution:null},{id:"41319",title:"Prof.",name:"Lung-Kwang",middleName:null,surname:"Pan",slug:"lung-kwang-pan",fullName:"Lung-Kwang Pan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/41319/images/84_n.jpg",biography:null,institutionString:null,institution:null},{id:"125292",title:"Dr.",name:"Katy",middleName:null,surname:"Satué Ambrojo",slug:"katy-satue-ambrojo",fullName:"Katy Satué Ambrojo",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/125292/images/system/125292.jpeg",biography:"Katy Satué Ambrojo received her Veterinary Medicine degree, Master degree in Equine Technology and doctorate in Veterinary Medicine from the Faculty of Veterinary, CEU-Cardenal Herrera University in Valencia, Spain.Dr. Satué is accredited as a Private University Doctor Professor, Doctor Assistant, and Contracted Doctor by AVAP (Agència Valenciana d'Avaluació i Prospectiva) and currently, as a full professor by ANECA (since January 2022). To date, Katy has taught 22 years in the Department of Animal Medicine and Surgery at the CEU-Cardenal Herrera University in undergraduate courses in Veterinary Medicine (General Pathology, integrated into the Applied Basis of Veterinary Medicine module of the 2nd year, Clinical Equine I of 3rd year, and Equine Clinic II of 4th year). Dr. Satué research activity is in the field of Endocrinology, Hematology, Biochemistry, and Immunology in the Spanish Purebred mare. She has directed 5 Doctoral Theses and 5 Diplomas of Advanced Studies, and participated in 11 research projects as a collaborating researcher. She has written 2 books and 14 book chapters in international publishers related to the area, and 68 scientific publications in international journals. Dr. Satué has attended 63 congresses, participating with 132 communications in international congresses and 19 in national congresses related to the area. Dr. Satué is a scientific reviewer for various prestigious international journals such as Animals, American Journal of Obstetrics and Gynecology, Veterinary Clinical Pathology, Journal of Equine Veterinary Science, Reproduction in Domestic Animals, Research Veterinary Science, Brazilian Journal of Medical and Biological Research, Livestock Production Science and Theriogenology, among others. Since 2014 she has been responsible for the Clinical Analysis Laboratory of the CEU-Cardenal Herrera University Veterinary Clinical Hospital.",institutionString:null,institution:null},{id:"201721",title:"Dr.",name:"Beatrice",middleName:null,surname:"Funiciello",slug:"beatrice-funiciello",fullName:"Beatrice Funiciello",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/201721/images/11089_n.jpg",biography:"Graduated from the University of Milan in 2011, my post-graduate education included CertAVP modules mainly on equines (dermatology and internal medicine) and a few on small animal (dermatology and anaesthesia) at the University of Liverpool. After a general CertAVP (2015) I gained the designated Certificate in Veterinary Dermatology (2017) after taking the synoptic examination and then applied for the RCVS ADvanced Practitioner status. After that, I completed the Postgraduate Diploma in Veterinary Professional Studies at the University of Liverpool (2018). My main area of work is cross-species veterinary dermatology.",institutionString:null,institution:null},{id:"291226",title:"Dr.",name:"Monica",middleName:null,surname:"Cassel",slug:"monica-cassel",fullName:"Monica Cassel",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/291226/images/8232_n.jpg",biography:'Degree in Biological Sciences at the Federal University of Mato Grosso with scholarship for Scientific Initiation by FAPEMAT (2008/1) and CNPq (2008/2-2009/2): Project \\"Histological evidence of reproductive activity in lizards of the Manso region, Chapada dos Guimarães, Mato Grosso, Brazil\\". Master\\\'s degree in Ecology and Biodiversity Conservation at Federal University of Mato Grosso with a scholarship by CAPES/REUNI program: Project \\"Reproductive biology of Melanorivulus punctatus\\". PhD\\\'s degree in Science (Cell and Tissue Biology Area) \n at University of Sao Paulo with scholarship granted by FAPESP; Project \\"Development of morphofunctional changes in ovary of Astyanax altiparanae Garutti & Britski, 2000 (Teleostei, Characidae)\\". She has experience in Reproduction of vertebrates and Morphology, with emphasis in Cellular Biology and Histology. She is currently a teacher in the medium / technical level courses at IFMT-Alta Floresta, as well as in the Bachelor\\\'s degree in Animal Science and in the Bachelor\\\'s degree in Business.',institutionString:null,institution:null},{id:"442807",title:"Dr.",name:"Busani",middleName:null,surname:"Moyo",slug:"busani-moyo",fullName:"Busani Moyo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Gwanda State University",country:{name:"Zimbabwe"}}},{id:"439435",title:"Dr.",name:"Feda S.",middleName:null,surname:"Aljaser",slug:"feda-s.-aljaser",fullName:"Feda S. Aljaser",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"King Saud University",country:{name:"Saudi Arabia"}}},{id:"423023",title:"Dr.",name:"Yosra",middleName:null,surname:"Soltan",slug:"yosra-soltan",fullName:"Yosra Soltan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Alexandria University",country:{name:"Egypt"}}},{id:"349788",title:"Dr.",name:"Florencia Nery",middleName:null,surname:"Sompie",slug:"florencia-nery-sompie",fullName:"Florencia Nery Sompie",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sam Ratulangi University",country:{name:"Indonesia"}}},{id:"428600",title:"MSc.",name:"Adriana",middleName:null,surname:"García-Alarcón",slug:"adriana-garcia-alarcon",fullName:"Adriana García-Alarcón",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"428599",title:"MSc.",name:"Gabino",middleName:null,surname:"De La Rosa-Cruz",slug:"gabino-de-la-rosa-cruz",fullName:"Gabino De La Rosa-Cruz",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}},{id:"428601",title:"MSc.",name:"Juan Carlos",middleName:null,surname:"Campuzano-Caballero",slug:"juan-carlos-campuzano-caballero",fullName:"Juan Carlos Campuzano-Caballero",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"National Autonomous University of Mexico",country:{name:"Mexico"}}}]}},subseries:{item:{id:"95",type:"subseries",title:"Urban Planning and Environmental Management",keywords:"Circular Economy, Contingency Planning and Response to Disasters, Ecosystem Services, Integrated Urban Water Management, Nature-based Solutions, Sustainable Urban Development, Urban Green Spaces",scope:"