Herve Seligmann

University of ChicagoUnited States of America

Hervé Seligmann\'s focus on mitochondrial DNA developed when searching for molecular mechanisms explaining developmental stability in lizards, a major topic in his PhD thesis. He described already >5 molecular processes affecting whole organism morphology and life history traits. This lead to uncover 4 types of cryptic coding systems, which he describes for vertebrate mitochondria. These range from switches between alternative genetic codes (mainly stop codon translation), expanded codons, and several alternative transcriptions, based on systematic alterations of the template DNA (research ongoing).

2books edited

3chapters authored

Latest work with IntechOpen by Herve Seligmann

The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.

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