\\n\\n
Released this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\\n\\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\\n"}]',published:!0,mainMedia:{caption:"Highly Cited",originalUrl:"/media/original/117"}},components:[{type:"htmlEditorComponent",content:'IntechOpen is proud to announce that 191 of our authors have made the Clarivate™ Highly Cited Researchers List for 2020, ranking them among the top 1% most-cited.
\n\nThroughout the years, the list has named a total of 261 IntechOpen authors as Highly Cited. Of those researchers, 69 have been featured on the list multiple times.
\n\n\n\nReleased this past November, the list is based on data collected from the Web of Science and highlights some of the world’s most influential scientific minds by naming the researchers whose publications over the previous decade have included a high number of Highly Cited Papers placing them among the top 1% most-cited.
\n\nWe wish to congratulate all of the researchers named and especially our authors on this amazing accomplishment! We are happy and proud to share in their success!
Note: Edited in March 2021
\n'}],latestNews:[{slug:"webinar-introduction-to-open-science-wednesday-18-may-1-pm-cest-20220518",title:"Webinar: Introduction to Open Science | Wednesday 18 May, 1 PM CEST"},{slug:"step-in-the-right-direction-intechopen-launches-a-portfolio-of-open-science-journals-20220414",title:"Step in the Right Direction: IntechOpen Launches a Portfolio of Open Science Journals"},{slug:"let-s-meet-at-london-book-fair-5-7-april-2022-olympia-london-20220321",title:"Let’s meet at London Book Fair, 5-7 April 2022, Olympia London"},{slug:"50-books-published-as-part-of-intechopen-and-knowledge-unlatched-ku-collaboration-20220316",title:"50 Books published as part of IntechOpen and Knowledge Unlatched (KU) Collaboration"},{slug:"intechopen-joins-the-united-nations-sustainable-development-goals-publishers-compact-20221702",title:"IntechOpen joins the United Nations Sustainable Development Goals Publishers Compact"},{slug:"intechopen-signs-exclusive-representation-agreement-with-lsr-libros-servicios-y-representaciones-s-a-de-c-v-20211123",title:"IntechOpen Signs Exclusive Representation Agreement with LSR Libros Servicios y Representaciones S.A. de C.V"},{slug:"intechopen-expands-partnership-with-research4life-20211110",title:"IntechOpen Expands Partnership with Research4Life"},{slug:"introducing-intechopen-book-series-a-new-publishing-format-for-oa-books-20210915",title:"Introducing IntechOpen Book Series - A New Publishing Format for OA Books"}]},book:{item:{type:"book",id:"843",leadTitle:null,fullTitle:"Insecticides - Pest Engineering",title:"Insecticides",subtitle:"Pest Engineering",reviewType:"peer-reviewed",abstract:"This book is compiled of 24 Chapters divided into 4 Sections. 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Section D provides information on insecticide resistance in natural population of malaria vector, role of Anopheles gambiae P450 cytochrome, genetic toxicological profile of carbofuran and pirimicarp carbamic insecticides, etc. The subject matter in this book should attract the reader's concern to support rational decisions regarding the use of pesticides.",isbn:null,printIsbn:"978-953-307-895-3",pdfIsbn:"978-953-51-4357-4",doi:"10.5772/1354",price:159,priceEur:175,priceUsd:205,slug:"insecticides-pest-engineering",numberOfPages:552,isOpenForSubmission:!1,isInWos:1,isInBkci:!0,hash:"88f3cc3c937f853057f544c152ef7491",bookSignature:"Farzana Perveen",publishedDate:"February 15th 2012",coverURL:"https://cdn.intechopen.com/books/images_new/843.jpg",numberOfDownloads:90427,numberOfWosCitations:173,numberOfCrossrefCitations:59,numberOfCrossrefCitationsByBook:2,numberOfDimensionsCitations:193,numberOfDimensionsCitationsByBook:4,hasAltmetrics:1,numberOfTotalCitations:425,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"February 22nd 2011",dateEndSecondStepPublish:"March 22nd 2011",dateEndThirdStepPublish:"July 27th 2011",dateEndFourthStepPublish:"August 26th 2011",dateEndFifthStepPublish:"December 24th 2011",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,8",editedByType:"Edited by",kuFlag:!1,featuredMarkup:null,editors:[{id:"75563",title:"Dr.",name:"Farzana Khan",middleName:null,surname:"Perveen",slug:"farzana-khan-perveen",fullName:"Farzana Khan Perveen",profilePictureURL:"https://mts.intechopen.com/storage/users/75563/images/system/75563.jpg",biography:"Dr. Farzana Khan Perveen (FLS; Gold Medalist) obtained her BSc (Hons) and MSc in Entomology from the University of Karachi, Pakistan, and MAS (Monbusho Scholarship) in Agronomy from Nagoya University, Japan, and a Ph.D. in Toxicology from the University of Karachi. She is the founder of the Department of Zoology and former controller of examinations at Shaheed Benazir Bhutto University, Hazara University, and Kohat University of Science and Technology. She is the author of 150 high-impact research papers, 135 abstracts, 40 authored books, 9 chapters, and 9 edited books. She is also a student supervisor. 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\r\n\tThis book intends to provide the reader with a comprehensive overview of the current state-of-the-art on the possibility to transform the different types of waste materials into useful products, zeolites, through conventional processes and innovative methods. The aim is to demonstrate that waste can be a problem or a resource depending on how it is managed.
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According to [2], the U.S. outsourcing industry’s revenue grew over 20 billion U.S. dollars from 2010 to 2019. Moreover, globally, the total outsourcing industry revenue increased from 93.1 billion U.S. dollars to 135.5 billion U.S. dollars.
With the blooming of outsourcing, academic researchers conducted studies to better understand the many aspects of outsourcing. To date, Google Scholar has listed approximately 390,000 articles related to the keyword “outsourcing” published since 2010. Although the researchers’ interests in outsourcing varied, in recent years many researchers were focusing on outsourcing with Information Technologies [3, 4, 5], Logistics [6, 7, 8], and Education [9, 10, 11]. Researchers are particularly interested in outsourcing with Information Technologies [5, 12], including issues related to cloud computing [13, 14, 15, 16] and security [13, 14, 15, 17, 18].
In the rest of this chapter, we will first give an overview of the historical background of the development of outsourcing, and the definition of outsourcing. We will then discuss benefits of outsourcing, including lowering cost, improving the focus on core competencies, receiving the best technology within the industry which the firms did not have, and increasing the employees’ flexibility. We will also discuss the risks or potential disadvantages of outsourcing. We will also discuss recent trends in outsourcing, focusing on the impact of new technologies including cloud computing and artificial intelligence.
Outsourcing could trace back to Rome for tax collection [19]. However, the concept of outsourcing was first proposed by Adam Smith in his book The Wealth of Nations [20]. This book posited that division of labor and specialization of labor are the key factors for productivity optimization. Smith argued that labor specialization promotes individual productivity and helps groups of employees cooperate with each other.
In the 1830s, innovations on railway networks and telegraph reduced the exchange time of both information and products. The development of the manufacturing industry allowed firms to enjoy the benefits from economics of scale and expand their business areas [21].
Later, in the post-war period, companies were advocated to conduct horizontal acquisition and vertical acquisition. At that time, proposers believed that conglomerate mergers’ strategy could help businesses earn better control over both production and market share [22].
However, between the 1970s and 1980s, academics continued to discover that the conglomerate firms were under-performing in the market [23, 24, 25].
Then in 1985, Williamson [26] proposed a new concept called Asset Specificity. Williamson illustrated that in order to optimize the company, the company needs to consider both production cost and transaction cost. Williamson identified the differences between these two costs as a function of asset specificity. In addition, Williamson’s Transaction Cost Theory [27] presumed that the most advantageous economic organizational structure is the one that was minimizing the transaction cost while maximizing the profit. Williamson defined Transaction Cost as the cost which summarized all the cost to make a transaction except production cost.
Williamson [26] proposed that economic institutions contained two characteristics - bounded rationality and opportunism. While in the exclusive contract situation, asset specificity would be added as a significant factor. When a circumstance consists of all three elements, the economic institutions will coordinate transactions to save limited rationality while protecting both sides from opportunism attacks. This concept was distinct from the traditional concept of profit maximization.
The concept of Asset Specificity helped explain the phenomenon of conglomerate firms under-performing in the market when they should be bringing great advantages to the business [28]. A Conglomerate merger is two or more economic institutions construct an exclusive contract with each other. Compared to the privately held company, the main concept of conglomerate firms already from profit maximization shift to coordinate transactions. Even though the conglomerate merger will reduce the company’s production cost, the transaction cost will increase since the company’s size is increasing.
Despite Williamson’s significant effort on enlightening outsourcing by transaction cost theory, according to [22], Tom Peter was the one who significantly influenced the companies back to concentrate on the firm’s core business.
Many firms were inspired by the Core Competency concept [29]. Core competency is a unique value that makes a firm stand out in the marketplace by utilizing its available resources and knowledge. However, the firms based on this concept to reengineering to more focus on the “core” [22].
Meanwhile, the public sector’s outsourcing is helping economic institutions to strengthen the idea of Outsourcing. Between the 1980s to 1990s, notably in the U.K., governments are using privatization and outsourcing to reform the public sector. The public sector’s reform set an example for firms about the strengths of Outsourcing. The reform also promoted the development of outsourcing in both the public and private sectors. The U.K. example influenced numerous firms to start to restructure their organizational framework to outsource unnecessary tasks and focus on the core activities [22].
As discussed above, outsourcing as a practical strategic tool has appeared for a long time; however, the official definition did not exist until 1997 [30].
The academics had been arguing about the definition since 1992. However, the broad definition of outsourcing is that it obtains activities that an organization has the knowledge and resources to execute, from outside of the organization [31].
Recently, Ishizaka et al. [1] examined the existing literature from 1994 to 2020 and came to a comprehensive conclusion:
“Outsourcing is a business agreement, either domestic and/or international (known as offshoring), and strategic management initiative for gaining a competitive advantage of a firm by contracting out their existing internal and/or external non-value added functions, and/or value-added functions, and/or core competencies to competent supplier(s) to produce products and/or services efficiently and effectively for the outsourcing firm.” ([1], p. 1, para 4).
Ishizaka et al.’s [1] definition contained multiple elements, including multiple branches and sub-branches. First overall and the most fundamental, Outsourcing is a business agreement. It indicates that demander and supplier reach a consensus through either oral or written agreement.
Outsourcing is a strategic management initiative that uses a contract-out the firm’s either existing functions and/or core competencies to earn the opportunity to stand out in the market. This indicated that companies could outsource not only the functions but also the core competencies to the third parties.
Last but not least, outsourcing can be a strategic management initiative by contracting out to qualified supplier(s) to efficiently and effectively produce products and/or services for the outsourcing firm to stand out in the market. This statement is to clarify that outsourcing does not need to be limited to products or services. A company can outsource their business process regardless of whether they provide either physical goods, non-physical goods, or both as long as this contract-out behavior can help the firm optimize productivity and quality.
With such a complex nature of outsourcing, Alexandre Dolgui and Jean-Marie Proth [32] provided some additional information to help clarify Outsourcing. Dolgui and Proth found that the frequent confusions for outsourcing are to separate outsourcing, offshore outsourcing, offshoring, and subcontracting.
The differences between outsourcing and offshore outsourcing are related to the location of the supplier and the outsourcing firm. Outsourcing commonly identified as both supplier and the firm both located in the same country. However, offshore outsourcing defined as the supplier is located in a country different than the firm. On top of that, offshore is classified as the firm constructed a branch in a different country.
According to Dolgui and Proth, practitioners such as managers were more likely to confuse the concept of outsourcing with sub-contracting. Sub-contracting is the firm contract-out partial works to another firm that contain specific resources and/or skills to provide better task results. Outsourcing, on the other hand, is the firm contract-out partial works to the supplier to allow the supplier to collaborate with the outsourcing firm.
In other words, sub-contracting only provides product and/or services that are specified in the contract; meanwhile, outsourcing is defined as the outsourcing firm establishing a partnership with the supplier. Dolgui and Proth pointed out that outsourcing requires some level of technical and organizational information exchange.
Lacity et al. provided a systematic analysis of the motivations of outsourcing [33, 34, 35]. They categorized outsourcing into business process outsourcing and information technology outsourcing [33, 34]. Business process outsourcing is contract-out the business process to the entity outside of the company. Information technology outsourcing is contract-out the information technology services to the entity outside of the company. Lacity et al. [35] explained with more details when merging the two as business services outsourcing. The types of outsourcing “include, but not limited to, financial and accounting, human resources, procurement, R&D, call centers/customer service, software development, software support, infrastructure management services, systems integration services, and legal service.”
Lacity et al. [33, 34, 35] analyzed over 400 empirical studies from 1992 to 2014. They discovered 19 independent variables frequently shown up crossing six factors [35]. They found that the outsourcing firm had multiple motives to make the outsourcing decision other than just cost-saving. Lacity et al. pointed out that the firm tends to make an outsourcing decision when the firm craves on optimizing the quality and flexibility of the services while the firm wants to have a supplier’s professional skills and global markets in order to focus on the critical services. In other words, the outsourcing firm is looking to use the minimum cost to get the best results and tends to focus on the “core” of the company. However, the firm also considers losing control as a negative effect. This factor will make the firm prefer to make a decision against outsourcing.
In addition to the reasons above, Lacity et al. [35] also found that the outsourcing firm also frequently consider transaction attributes (such as high transaction costs, difficulty formalizing knowledge, high service complexity, and lack of service standards). The outsourcing firm will be more confident when the outsourcing firm possesses a certain level of technical and methodological capabilities. One interesting point is, when the nature of the firm is high degrees of internationalization, the firm more prefers outsourcing and offshoring.
Building on [33, 34, 35], Asatiani et al. [36] ran a regression based on a rich data set of 337 companies. They found that the motivation of outsourcing seems to be more dynamic than linear. They point out that even though cost-saving and focus on the “core” is positively correlated with outsourcing, the need for external expertise is a negative factor.
With all the advantages that outsourcing brings along, there are some risks of outsourcing that require the manager to notice before and after making the outsourcing decision.
Aron et al. [37] proposed that outsourcing risks can be divided into four categories: strategic risks, operational risks, intrinsic risks of atrophy, and intrinsic risks of location. Strategic risks referred to the risks related to opportunistic behavior for both the outsourcing firm and the supplier. The agent problem always comes with the same two reasons: the supplier did not work as hard as the outsourcing firm expected. The outsourcing firm manager cannot be aware of the manager hiring unqualified supplier due to lack of information or resources [37].
Information Leakage issues can happen to the supplier either unintentionally or intentionally. The supplier can either purposely steal the information the outsourcing firm provided and developed as supplier’s new advantages or leak the information to the third parties accidentally due to the supplier’s imperfect system structure.
Opportunistic renegotiation can be triggered when the supplier realizes that the outsourcing firm heavily relies on their products or services and there are no better solutions in the existing market. In that scenario, the supplier will push the outsourcing firm to renegotiate the distribution of benefits to ensure the supplier’s profit maximization.
Operational risks referred to the risks of communication and cooperation between the outsourcing firm and supplier in the period of outsourcing. Operational risks can happen in many circumstances, such as complexity of operations, geographic location differences between the supplier and the outsourcing firm, and the communication barriers and transmit systems between the supplier and the outsourcing firm. Benefit from the information technology rapidly developing, the operational risks keep decreasing. However, lowering the operational risks required to transform massive information outside of the outsourcing firm will significantly increase information leakage’s strategic risk [37].
Intrinsic risks of atrophy referred to after the outsourcing decision was made, the outsourcing firm will lose the professional whose expertise in the outsourcing activities. Depending on the outsourcing firm’s strategy is focusing on cost-saving or maintain the company’s control, this issue can be big or small. It also can interact with the strategic risk of opportunistic renegotiation. When the supplier posse a renegotiation request, if the outsourcing firm still maintains the professions with such expertise, it increases its bargaining power.
Intrinsic risks of location referred to the risk of outsourcing the firm to a remote location. The location risks can be but are not limited to geopolitical risks, sovereign risks, and exchange rate risks. This type of risk ties to the specific of outsourcing location; each region had its own unique cultural and political background. Without the manager understanding the supplier’s country in advance, it can increase the possibility that the outsourcing firm must take the extra cost from not familiar with the supplier’s country. This type of risk often happens when a manager makes an offshore outsourcing decision.
Overall, the types of risks summarized the possible directions a firm can meet the obstacles and lead to an outsourcing decision’s failure. Next, this chapter would like to introduce the risk of outsourcing based on outsourcing processes to understand outsourcing risks further.
Shi [38] posed that business process outsourcing usually contains two types of risks: market performance risks and organizational risks. Based on the time of outsourcing, Shi divided the risks further into four types. However, within market performance risks when the firm just outsourcing, the balancing cost and outsourcing results and increase customer complaints are tie back to agent problem. Meanwhile, operation shut-down is the side effect of intrinsic risks of atrophy. After time passes, Shi mentioned the risk could become the price or contract creep and low innovation rate. For the change of the price or contract, it can tie back to the opportunistic renegotiation. As a result of operation shut-down, the firm will have a low rate of innovation due to the profession’s loss within such expertise. This risk can refer back to intrinsic risks of atrophy.
For organizational risks, when the firm just outsourcing, the firm will experience losing the specific knowledge that the firm outsourcing to the supplier, loss of confidential information, loss of employees whose contained loyalty and capability and lower the existing employee’s morale and productivity. The loss of specific knowledge, loss of employee, and lower existing employee’s morale is the side effect of the operation shut-down. However, this type of risk tie to the intrinsic risks of atrophy, which more rely on the manager’s decision on cost-saving or preserve the bargaining power. On the other hand, loss of confidential information is the risk of transferring to a new system which indicated this risk tie to information leakage. The risk of lower employee productivity can interpret from two aspects. One of the risk is that the employee’s productivity is lower due to the working process has changed due to the firm’s recent outsourcing decision. The employees require extra time to adapt to the new methods of doing their old job. The other interpretation is due to the operation shut-down, the resignation wave within the firm, and the low morale among employees, the existing employee became low productive. Lower employee productivity risk can refer back to intrinsic risks of atrophy since all of them are the side effect of operation shut-down.
After the firm adapted to outsourcing, the firm can have organizational risks such as relying on the supplier, losing control of strategic assets, locking in between the outsourcing firm and supplier, adapting to the incompatible architectural style, and unsuitable competitive signaling, Loss of innovation capabilities and strategic flexibility.
Among all the risks above, the incompatible architectural style and unsuitable competitive signaling can tie to both the agent problem and operational risks. The incompatible architectural style indicated that the firm partially sacrifices its operating mode to fit the style supplier provided to cooperate better. And unsuitable competitive signaling indicated the firm permitted some of the non-value-added terms to earn the opportunity to work with the supplier or make the outsourcing process run smoother at the beginning of the outsourcing. However, when time passes by, the existing terms lost their advantages. These two risks can happen cause of the firm lack of necessary information to discover a suitable supplier or in the existing market, there is no existing supplier that can perfectly fit the outsourcing firm’s requirement. Therefore, they can tie to both agent problem and operational risks.
As for the lock-in, loss control on strategic assets, loss of innovation capabilities and strategic flexibility, and reliance on the supplier, they all can tie to intrinsic risks of atrophy. Lock-in is due to asset specificity. When the outsourcing firm and supplier made a contract, the outsourcing firm and the supplier are naturally locked in. Cause of the characteristics of lock-in and the how much the outsourcing firm is sacrificing to reach an agreement, the outsourcing firm will lose some level of strategic flexibility or control on strategic assets. Furthermore, on a cost-saving basis, the operation shut-down decision is made, the risks of innovation capabilities loss and reliance on the supplier will exist due to the talent loss. But after all, these risks all relate to the nature of outsourcing and the firm’s decision of cost-saving. Therefore, they all refer to intrinsic risks of atrophy.
Aubert et al. [39] in total list seven undesirable outcomes: unexpected transition and management cost, switching cost, expensive contractual amendments, disputes and litigation, service degradation, increased cost, organizational competencies loss, and hidden service cost.
Unexpected transition and management costs are attributed to three risk factors: either the outsourcing firm and/or the supplier’s lack of knowledge on the outsourcing, the supplier unfamiliar with the outsourcing firm, and unfamiliar with the legal environment.
Both outsourcing firm and the supplier can increase the transition and management cost when either of them is unfamiliar with the outsourcing process. Furthermore, this situation increases the overall cost for the outsourcing firm to get their expected results. The reason behind that is the outsourcing firm’s lack of knowledge of either the outsourcing process or awareness on the supplier’s qualification. Therefore, either the outsourcing firm or the supplier’s lack of experience in the outsourcing process is the agent problem. Meanwhile, when the supplier is unfamiliar with the outsourcing firm, the firm needs to train the supplier the same as the new employees. The extra training requires the firm to pay the additional cost to smooth the outsourcing process. These risks only exist when the firm needs to adapt the services or unfamiliar system which the supplier provided. It can be identified as operational risks. Also, unfamiliar with the legal environment can be classified as intrinsic risk of location because the legal system gets involved. If the supplier and the outsourcing firm are located in the same region, the supplier should share the same legal system with the outsourcing firm. Then less likely, both sides need to experience the risk of an unfamiliar legal environment unless one of them or both of them are new to outsourcing. Hence, unexpected transition and management cost and its risk factors can be identified as Agent Problem, Operational Risks, and Intrinsic Risk of Location.
Switching cost as an undesirable outcome contained lock-in, repatriation, and transfer to another supplier. Switching cost is the cost the outsourcing firm needs to consider when the firm needs to consider replacing the supplier or not. Asset specificity, a small number of suppliers, economic scope, and interdependence of activities are the risk factors associated with switching costs. Asset specificity is the characteristic of a contract; the number of suppliers and the economic scope decided the outsourcing firm’s interdependency level. All the risk factors related to switching cost can be identified as opportunistic renegotiation and intrinsic risks of atrophy. After all, all the risk factors related to switching cost depend on how unique the supplier’s resource or knowledge—the more unique, the higher the switching cost. The uniqueness provided the supplier the power to renegotiate and influence the outsourcing firm’s decision-making on withholding specific professions to remain bargaining power to the supplier.
Expensive contractual amendment is the cost of adjusting the contract caused by uncertainty, technological discontinuity, and task complexity. Uncertainty indicated that the supplier’s performance could not be measured will be forced both sides to adjust the existing contract to confirm shift the invalid performance measurement to the new performance measurement. Invalid performance measurement can happen when either task is too complex or the supplier cannot provide a good performance for the outsourcing firm. The task complexity will discuss shortly. This suggested uncertainty is both agent problem and opportunistic renegotiation. When no supplier in the existing market provides a discontinued technology, the outsourcing firm is forced to renew the contract with the supplier to accept the substitute solutions. Task complexity related to the uncertainty of the future needs, Aubert et al. [39] posed that when the task is too complex when changes appear, both sides are forced to renegotiate the contract. In general, expensive contractual amendments and their related risk factors are classified as opportunistic renegotiation mainly and attached the agent problem.
Disputes and litigation as the undesirable outcomes mainly indicate the issues created by contracts, agreements, and legal environments. Measurement Issues, Lack of knowledge in outsourcing contracts from either the supplier or the outsourcing firm, unfamiliar with the legal environment, and poor cultural fit are the risk factors for disputes and litigation. As mentioned earlier, the measurement issue is the opportunistic renegotiation and agent problem, lack of knowledge in outsourcing contracts from either the supplier or the outsourcing firm is agent problem, and unfamiliar with the legal environment is an intrinsic risk of location. Poor cultural fit belongs to the intrinsic risk of location. Poor cultural fit originated from the cultural differences between the two regions.
Service degradation indicated that the outsourcing company’s service after the outsourcing decision is not as good as the firm before outsourcing. Such downgrade is caused by interdependence of activities, the supplier unfamiliar with the outsourcing firm, the size of supplier, supplier’s financial instability, measurement issue, and task complexity. As shown before, the interdependence of activities is opportunistic renegotiation and intrinsic risks of atrophy, the supplier unfamiliar with the outsourcing firm is operational risks, the measurement issue is agent problem and opportunistic renegotiation, and task complexity is opportunistic renegotiation. Earl [40] argued that the quality of service largely depends on the supplier’s size, financial stability, and expertise. Since the size and stability are the characteristics of determining is the supplier a qualified supplier or not, the supplier size and supplier’s stability are referred to as agent problem.
The increased cost is related to the risk factors of the supplier’s lack of knowledge with contract management, measurement issue, and the supplier unfamiliar with the outsourcing firm. When the supplier performance but both sides could not come up with a valid measurement to determine the quality of the supplier’s performance, it can be caused by either the outsourcing firm lack of effective monitoring methods or the supplier did not provide enough details allow the outsourcing firm to inspect the performance quality.
Organizational competencies loss means that due to the outsourcing firm’s getting contract-out to the supplier, the outsourcing firm may experience the loss of the professions and knowledge related to the outsourced part. Organizational competencies loss is connected to the risk of contract scope, close to the core competency, and interdependence of activities. Scope of contract means the more outsourcing firm contract out to one supplier, the harder the outsourcing firm can maintain independence. Meanwhile, when the outsourcing is too close to the “core,” the outsourcing activity will cause the outsourcing firm to lose the essential skills [29]. Moreover, this kind of loss can have a negative impact on the future of the outsourcing firm. Organizational competency loss can be identified as intrinsic risks of atrophy since all the risks are shown up after outsourcing behavior happened. The talent loss situation from Intrinsic risks of atrophy can lead to opportunistic renegotiation due to the outsourcing firm heavily relying on the supplier.
The last undesirable outcome is the hidden service cost. Hidden service cost contained three risk factors: task complexity, measurement issue, and uncertainty. Agency theory suggested that when the supplier on purposely created measurement issues to increase the cost assessment challenge due to low morale, then more than likely hidden service cost will increase.
In summary, information technology outsourcing is involved in all four risks. Unlike business process outsourcing, Information technology outsourcing tends to more frequent to have agent problem, Intrinsic risks of atrophy, and opportunistic renegotiation. In other words, the outsourcing firm manager should pay more attention to talents lost and its series of consequences. Simultaneously, the manager should work harder to identify a qualified supplier to avoid undesirable outcomes.
As Asatiani et al. [36] mentioned, the outsourcing factors are dynamic. Many firms are now contracting-out their parts to multiple suppliers [41, 42]. Outsourcing firm can contract multiple parts to multiple suppliers. To increase the firm’s control, the manager can even split the business process into several pieces for different suppliers. Therefore, each outsourcing firm will experience its unique challenges since they had its unique combination of outsourcing.
Existing literature tends to study the outsourcing risk as to the risk management cases instead of developing a measurement tool [43, 44, 45]. In addition, many studies only study the Risk Assessment in Information Technology Outsourcing [46, 47, 48].
When Aron et al. [37] posed the outsourcing risks into four categories, they also proposed a task decomposition of the process that the bank requested. This process had three steps: identification, formulation of retention strategy, and retention. Aron et al. adjusted this method to fit for outsourcing risk assessment. Identification is based on the four risk categories to identify an outsourcing firm’s risks. The next step, the formulation of retention strategy, is managers and researchers propose multiple solutions to determine the best solution for the situation based on the risks. The last step is retention. This step is to execute the solution determined in the second step. For more details, see [37].
Welborn [49] also proposed using a specific assessment tool to help managers and researchers to identified outsourcing risks. Welborn suggested using Failure Mode Effects Analysis (FMEA) to identify outsourcing risk since FMEA is used for risk management. FMEA was evolved from Failure Mode, Effects and Criticality Analysis (FMECA). FMECA was proposed in [50]. It is a traditional criticality analysis assessment tool to identify item failure. FMEA become a popular tool for many industries used to conduct safety and reliability analysis related to systems, products, processes, and services [51].
FMEA suggested that users identified risk categories and then detail specific potential risks. After that, based on severity, frequency of occurrence, and detectability, to score each risk and calculate the Risk Priority Number (RPN) by multiple all three aspects’ scores. They are then using a pareto distribution to analyze the RPN of each risk and develop a solution against the high RPN. FMEA is an assessment tool that is able to execute when the process occurs changes repeatedly [51].
Lee et al. [42] take advantage of FMEA’s universally suitable features, they used the adjusted the FMEA framework Supply Chain Risk-Failure Mode and Effect Analysis (SCR-FMEA, [52]) and combined it with Monte Carlo Simulation (MCS) to conduct a risk assessment tool which contains both qualitative and quantitative risk assessment.
Lacity et al. [35] found that there still many mysteries to be revealed. To better understand the motivation of outsourcing, Lacity et al. call for more studies related to governance determinants since there are limited studies on such areas. Lacity et al. [35] encouraged researchers to extend their interest to relate outsourcing with innovation, disclosed more about environmental factors’ relationship with outsourcing, and understand more about the outsourcing firm’s capabilities and the supplier. Lacity et al. suggested exploring more on outsourcing configurational methods, discovering new pricing models other than fixed-price model and time & materials model, understanding better on business analytics sourcing, and revealing emerging models. They discuss how outsourcing and its related personnel positively influence marginalized populations and their roles in sustaining the planet. The other future directions are discussed in advisors, the threat of cybersecurity, and the influence of service automation.
In addition, [53] point out that many researchers are aware of lacking longitudinal datasets, and they encouraged researchers to conduct longitudinal studies to help understand outsourcing. Another suggestion provided by [53] is to extend the related personnel to the parties responsible for outsourcing and the other stakeholders whose careers are impacted and/or threatened by the outsourcing decision.
Kakabadse and Kakabadse [41] concluded that outsourcing in the 2000s was more focused on cost management and functional specialization, and differentiation strategy and market response capability would become of the future. The outsourcing cost of data storage, e-commerce, and website setup was drastically reduced. Small and Medium-sized enterprises tend to seek contract-out to the third party by paying the monthly flat fee. In addition, the outsourcing process is from carrying non-core function moving to the core, from a single function extend to a complete business process and/or value-added intangible assets. Meanwhile, outsourcing firms were shifted from manufacturing to small/medium-sized enterprises and public sectors.
Also, the ways of cooperation between the outsourcing firm and the supplier became looser. The outsourcing firm tends to change from recruit single suppliers to multiple suppliers. Moreover, the outsourcing firm tended to produce a white label product to reduce the cost further and maximize the profit. The outsourcing firm also intends to construct a joint venture partnership with the supplier to allow the supplier to join the decision-making process and bear the cost together. Meanwhile, the payment method changed from pre-payment to pay-on-demand.
Due to the rapid development of outsourcing, the company’s concept had changed from vertically integrative diversified corporation to the networked enterprise specialized corporation that seeks the best variety in the enterprise network. Also, the outsourcing firm tends to focus on cost reduction of R&D and systems innovation. The supplier tends to just install and run new systems instead of takeover the existing assets. Moreover, the outsourcing firm was transferred their habit of contract-out the entire complex operation to one supplier to assign multiple suppliers based on the professional requirements of each area.
Because of the development of technology, more and more information technology outsourcing strategy has discovered. Hanafizadeh and Zareravasan [53], based on their review of 91 Information technology outsourcing studies published between 2000 and 2018 in over 50 journals, summarized that the following seven strategies are the mainstream strategy of ITO: cloud computing, IT operations and maintenance outsourcing, information system development outsourcing, BPO, offshore outsourcing. The outsourcing firm shows a trend on relying on machine’s computing capabilities and using a machine to replace human for repetitive behavior.
Before we discuss who the new player is in the outsourcing business and the pros and cons, let us briefly clarify some of the concepts first. This section will adopt the concept of cloud computing, big data analytics, and service automation.
Cloud computing is a shared computing technology where software and hardware cooperate with the real-time network to provide users a service which allows user access certain supplier-provided services or functions remotely. Cloud computing consists of Software as a Service (SaaS), Platform as a Service (PaaS), and Infrastructure as a Service (IaaS) [54, 55].
Big data analytics is human adopting advanced analytics techniques on the big data set [56].
Service automation is a concept proposed by [57]. Service automation indicated the service sector used a machine to provide service instead of a human. Lacity et al. [35] referred that service automation as a machine that replaces humans to accomplish highly perceptual tasks and highly cognitive tasks. Brynjolfsson and McAfee [58] believed that the first machine age existed in industrial revolution. At that time, machines replace humans’ manual labor. Furthermore, the second machine age is the era in which machines replaced humans for mental work.
Davenport and Ronanki [59] categorized artificial intelligence application in business into three categories: process automation, cognitive insight, and cognitive engagement.
Process automation is the robot using robotic process automation to automate the digital and physical task. The machine simulates humans to input and output information from multiple information technology systems. Cognitive Insight is the robot using massive user data to predict users’ behavior and preferences based on algorithms. This kind of robot is usually used for optimized job performance for machines. The tasks that the machine needs to accomplish are too complex for humans; therefore, human jobs are unaffected by this type of machine [59].
Cognitive Engagement is the robot use intelligent agents, machine learning technology, and natural language processing chatbots to interact with a human.
Cloud computing is a technology that allows customers to access products, resources, and/or services remotely by using the software as an interface regardless of the hardware setting. Big data analytics is a technology in which humans use massive data to explore the unfound facts from data producers using the analytic technique. Service automation is a technology using the robot to substitute partial mental work. Due to technological development, the robot is joining the outsourcing industry.
Computer and machine bring great advantages for business. They can help the firms to optimize their efficiency. Meanwhile, they also contained multiple risks and challenges. The following section proposes the possible benefits, challenges, and risks of cloud computing and service automation in outsourcing to bring researchers and practitioners some thoughts.
Mainly Cloud Computing Technology contained three benefits: cost-saving, flexibility, and rapidity. One of the main benefits for businesses to select a cloud computing service is to reduce their investment budget in IT [60]. The on-demand pricing model, on some level, exempts the user’s partial cost to access the service and the upfront cost to establish such a service [61]. For example, developing a virtual machine algorithm on optimizing resource allocation is the cost that the firm might require to pay upfront [62].
Cloud computing outsourcing allows the firm to enjoy flexibility at the level of allocating resources. The firm is buying the resource based on real-time demand instead of pre-purchased hardware and software. The charming part of such flexibility is that the firm does not need to pay additional costs for idle digital storage space [61].
The firm exploits the characteristics of rapid and flexible cloud computing to conduct many strategies and product tests to determine the best solution for the company [63]. Moreover, Cloud computing allows the firm to rapidly gather the required resources and provide a fundamental infrastructure within a few days [60].
Service automation’s benefit needs to target by each specific technology. Process automation is the lowest cost among the three robots and had low user learning cost to access this service [59]. Process automation can help the outsourcing firm save massive time that the employees spend on repetitive low-level mental tasks. In addition, it works excellent for multi-system cross-referencing. This indicated that if a company shifts service to a different provider when a contract is over, the process automation can play the role of a middleman to help smooth the data transfer process.
Cognitive insight mainly helps the outsourcing firm optimize machine’s job performance, which means this type of robot will not steal human’s job because humans are unable to accomplish a job that this type of robot does [59]. Another benefit is that since this kind of robot has a cognitive function, it indicated that the robot has self-learning and self-optimization functions in understanding users and optimizing the quality of future data collection.
Cognitive Engagement mainly simulates human interaction with customers, this type of robot’s cognitive function is enhanced in creating a solution for the users and simulating human language [59]. The benefit of this kind of robot is freeing customer service time from answering a large number of repeated, basic questions.
Davenport and Ronanki [59] found that over half of the company executives they interviewed (51%) motivated by service automation can optimize its products. In addition, many executives agree that service automation can help optimize internal business operations (36%), free up employees to conduct a more creative task (36%), make a better decision (35%), product innovation (32%), optimize external business process (30%), extent the market (25%), access and rational use of scarce knowledge (25%), and only close to one-fifth of the executives (22%) mentions on use service automation to streamlining the company population. This indicated that for most managers, using robots to replace humans is not the primary purpose of bringing in the robot to the company.
For cloud computing services, challenges and risks exist for both the service provider and the users. Alali and Yeh [60] expressed their concern about data security risks and the importance of standardization guidance for cloud computing. For service providers, the security risk is to protect all the data from leakage by third parties.
Data breaches are becoming more and more common. Verizon [64] found 3,950 confirmed data breaches during the period from the beginning of November 2018 to the end of October 2019.
Verizon found that the most common cause for data breach involved hacking (45%), errors (22%), social attacks (22%), malware (17%), misuse by authorized users (8%), and physical actions (4%). Meanwhile, most of the breaches conducted by the individual outside of the company (70%), over half of them involved organized criminal groups (55%), some of them involve inside job (30%), and perpetrator involving partner (1%), multiple parties (1%), and an attacker alliance which had four or more members in a single breach (4%) are rare to see. Verizon found that 72% of the breaches target large companies. Moreover, Verizon emphasized that since the business is trending into cloud-based solutions, the use of stolen credentials would increase in the future.
For the service clients, the security risk is to ensure the data storage in the outsourced company did not leak to the supplier company (service provider) and/or the unrelated third parties [60]. Cannon [65] also suggested that the cloud computing designer should focus more on optimizing data privacy protection.
Of course, the proposals above are not groundless. Verizon’s report showed that over half of the victims (58%) from the data breaches experience personal data leakage. This indicated that the outsourced company’s information gets leakage, and outsourced firm’s customers will also be affected. For example, Adobe in 2013 got a data breach that impacted at least 38 million of their customers. The hacker stole 3 million credit card records and login information from Adobe’s users. On this basis, tens of millions of user accounts may have been compromised. Even there are risks for the cloud computing service company (the supplier). However, the outcome of a data breach can affect the outsourced firm since the customers belong to the outsourced company instead of the cloud-service provider.
Another risk that is more concerned by the cloud supplier but might affect the outsourced company is local laws and regulations. Since data can be stored anywhere, the cloud service provider and its clients should pay attention to the laws and regulations where the data is stored and related trans-border laws [66]. For example, United States had no single principal data protection legislation [67]. Meanwhile, multiple laws and regulations are available at the federal and state levels. Therefore, the cloud service provider and the outsourced firm need to make sure nothing is crossing the line.
As for service automation, [59] found serval challenges exist when a company makes a decision to go service automation. They revealed that close to half of the manager found that it is difficult to retain existing process and system while adopting the service automation (47%), many of the managers discovered that the cost of technologies and expertise are expensive (40%), the managers unfamiliar with service automation and its mechanism (37%), lack of professions in Technology areas (35%), Technology is not yet mature (31%), and technologies have been oversold in the market (18%).
Overall, the challenges discovered from [59] indicated that the obstacles for the outsourced firm could cause by service automation is a newly developing technology. This means that it will be expensive, knowledge and professions are scarce, and the majority of the population unable to understand it. Moreover, since it is a newly developing technology, it also indicated that this technology has many areas await perfection. Meanwhile, the cost of business structure optimization is a crucial concern above all the expense of bringing in the new technology. And of course, last but not least, the concern of robots replacing humans.
The risk section adopts the risk framework of [37] to discuss cloud computing and service automation risks. The risks contain strategy risks, operational risks, intrinsic risks of atrophy, and intrinsic risks of location. Among them, strategy risks include agent problem, information leakage, and opportunistic renegotiation.
Firstly, there is the strategy risks-agent problem. Aron et al. [37] explained that the agent problem usually indicated that the supplier’s outcome did not meet the outsourced firm’s expectation and/or the outsourced firm’s lack of resources to identify an unqualified supplier. In other words, the outsourced firm felt that they did not get what they paid for. For computers and robots, it is hard to tell whether they “work hard enough.” However, based on the supplier’s performance, the outsourced firm can determine if the service that the supplier provided is over-price or not.
Choosing a qualified supplier can help the outsourced firm reduce the risk of information leakage in both the cloud computing and service automation areas. The qualified supplier should be the supplier who is qualified both morally and in capability. The capability indicates that the supplier can protect the data by using practical tools and algorithms at both the software and hardware level. The supplier should have the ability to protect the outsourced firm’s information both digitally and in-person from both outside of the company and the inside job.
In addition to capability, researchers found that the moral standard is an underestimated factor. Many papers did not consider discovering the moral of the supplier. However, recently, moral becomes more and more critical. Especially now, moral can be the factor that increases opportunity risk. To prevent the moral risk evolved into opportunity risk in opportunistic renegotiation, the authors suggest that an individual third party in either public sectors and/or private sectors construct a standard or guideline to help service providers practice business morally in cloud-computing area and service automation area.
Secondly, there is the strategy risk-information leakage. This indicates that the risk of both cloud computing and service automation will rise continuously. Therefore, the demand for improving data protection is increasing. However, in service automation, there is a dilemma for both the supplier and outsourced company. When the robot uses the black-box model to conduct a prediction and analysis, it significantly increases data security and privacy since no human can “look inside” to see how it works. This can provide the outsourced firm deniability on the outsourced service because they do not have access to the robot and the knowledge. All they get is the results.
However, the white-box model allows inspection from humans, but being able to inspect the robot’s working mechanism may also indicate that individuals can access the client’s confidential information. The supplier may violate the outsourced firm’s data privacy.
Winfield and Jirotka [68] conducted an in-depth discussion on a dilemma between the right of human privacy and for reducing the public harm created by the black-box model. They referenced the “black box” from flight data recorders and proposed an insight that the service provider should create an ethical black box inside the black-box model robots to record the sense data and the decisions. Meanwhile, they also suggest that robots develop moral values to fit human interests.
Thirdly, there is the strategy risks-opportunistic renegotiation. If one party completely controls the relationship, one will gain greater profits and/or voices.
With the trends of cloud solutions and big data Analytics, everything is heavily data related. Even the service automation (such as the cognitive insight and cognitive engagement technology) requires users’ data to analyze, predict, and improve. Data become essential for profit. Hence, data protection has become the key to winning the competition in the marketplace.
An immoral cloud computing service supplier may get involved in the data breach and identity stolen in such a condition. However, the service automation outsourcing firm will experience the same harms as cloud computing service plus the company’s core strategy or the newly developed technology got duplicated or stolen.
Worst scenario, the supplier based on the customers and technologies the outsourced firm provided to optimized and develop an upgraded version of substitute product/service. The outsourced firm may be forced to pay to become the middleman between the supplier and the customers. The outsourced firm forced the founder to transfer to its distributor.
The mechanism of this scenario is the same as when the firm in the 20th century determined automated the internal business process, due to the automation has evolved into too complicated. The firms began to have to outsource the process [69]. However, in this case, the outsourced firm did not force to outsource the business process. The firm was forced to outsource the core competence, which made them unique in the market.
Once the outsourced firm is caught in this predicament, it is difficult to leave this situation. The robots can optimize the product/service so rapidly that no human can follow, the outsourced firm became experienced the dilemma of either the firm become the distributor of the supplier company under the pressure of peer competition, or the entire company needs to experience a path shift in the core competencies.
To avoid this situation, the authors suggest focusing on agent problem and information leakage to seek solutions. First of all, if the outsourced firm can find a morally qualified supplier, this situation can be eliminated. Of course, most of the time, the outsourced firm did not have the resource and information to avoid unqualified suppliers is the reason push the firm into this situation. That is why data protection capability comes along. When a supplier is qualified both morally and in capability, the supplier can design an encryption algorithm and safety code that only the client (the outsourced firm) can access the data and/or the results and services from a black-box model robot. In this way, even the supplier firm did not have access to the outsourced firm’s data and knowledge. Even when an error occurs, the firm can invite the government and the public to inspect the supplier firm to fix the issue.
Fourthly, there is the operational risks. Operational risk happens between the supplier and the outsourced firm when outsourcing is on-process. It usually is the risk of the communication and/or transmission systems between the supplier, and the outsourced firm is different. This risk exists at the beginning of the new outsourcing relationship for both cloud computing and service automation. The more the outsourced firm changed the supplier, the operational risks increase. If the firm changes its supplier every three years, the operational risk will higher than the firm changes its supplier every five years.
However, changing the supplier is more expensive for the first time change to cloud computing and service automation. When the firm first outsources cloud solutions and service automation, the firm needs to take risks and costs to digitize all the existing information. Also, service automation requires optimizing the business structure to fit for service automation. After that, when the outsourcing company shifted between the suppliers, they already had the foundation to work with cloud computing service and service automation. All they need to do now is to transmit the data and adjust the existing structure to fit the new supplier better.
Operational Risk and its cost now are turning into a common obstacle for the outsourcing firm executives who preferred the service automation technology. After all, nearly half of the executives in [59]‘s study found that the existing business structure is not compatible with service automation technology.
Fifthly, there is the intrinsic risks of atrophy. Due to now the cloud computing and service automation are still a newly developing technology, this risk exists when the firm decides to adopt cloud computing and service automation. This is one of the main issues discussed in [59]. The executives that adopted service automation technology disclosed that the service automation technology is so complicated that the professions are scarce and expensive. The executives have difficulty understanding the technology.
For cloud computing, the challenge and the risk are similar. Maybe cloud computing will be a little user friendly than service automation when it comes to the feeling of use. However, when it comes to data protection and maintenance professions, the outsourced firm will have to outsource all the services to the supplier firm who is storing the outsourcing firm’s data since the Encryption Algorithm, the hardware, and the software is all owned by the supplier.
Besides, there is the intrinsic risks of location. For both cloud computing and service automation, the main issue for this risk is where the location is that stores all the data. When data is transfer across states and even countries, the Intrinsic Risks of location increase.
Last but not least, there is one more challenge: the money issue. Davenport and Ronanki [59] showed that 40% of executives disclosed that the technology is too expensive. Meanwhile, an artificial intelligence project launched by the MD Anderson cancer center using IBM’s Watson cognitive system to diagnose and recommend treatment plans for certain forms of cancer got suspend due to the cost of the program is rising to $62 million in 2017. This example gives an example of how expensive service automation technology can be. The large corporations might be able to handle such a price, but it is hard for small and medium firms to access the benefits of service automation such as IBM’s cognitive system.
With this challenge, the authors of this chapter suggest the outsourcing firm with the same or similar interest construct an alliance to group all the outsourcing firms’ budgets. The alliance can determine the permissions of the technology based on agreement or contract for each type of alliance member. However, the alliance is the one sign the contract with the supplier and fund the supplier’s expensive new technology.
In recent decades, the supply–demand relationship in outsourcing is leaning toward buyer’s market. However, due to the advantages that computers and robots created, the outsourcing industry will fall back to the seller’s market.
In this section we provide some suggestions and recommendations for researchers and practitioners.
Davenport and Ronanki [59] disclosed that only 22% of executives consider service automation as the solution to cut off headcount. Even though the robot is great, but the errors are more invisible than the previous. Davenport and Ronanki [59] suggested that the reallocated employee can switch to a big data analyst. However, for the front-line employees, can the trial-and-error clerk be their next career opportunity? Amazon Echo’s example showed us that some of the errors might be detected only by humans. Does the outsourcing firm need the human agents to trial run and detect the possible robot issues before the product or service release to the public? Since the ultimate question is “will robots replace human labor or not?” this paper calls for future researchers to record and track the executive’s decision making after the service automation outsourcing to reveal how the managers avoid the dismissal tide and relocate the existing employees.
Due to the dynamic, complex nature of its rapid development in the outsourcing industry, we feel the need to enhance the call for paper on longitude study. Based on the challenges section disclosed above, the tools and standardization of data protection are awaiting exploration and perfection. How to handle the balance between human privacy and artificial intelligence black-box model should bring more attention. We suggest that future researchers join the discussion and provide more suggestions and guidelines to help the industry construct such an issue.
We also call for a paper on the education field to discuss the future needs for human resources. Now, society is starting to use robots to help humans live better, but it already showed the challenge of the public unfamiliar with the robots and their working mechanism. Are future talents need to improve such skills? Or is this the service supplier’s obligation to make robots more user-friendly? We call for more papers on the topic of cloud computing and service automation in outsourcing. In addition, we call for more empirical studies to reveal the pros and cons of cloud computing and service automation. For the practitioner in the outsourcing industry, this paper recommends the executives consider constructing a network that allows all the buyers group their limited budgets to gain access to high-tech to help the business lower the cost and optimize the business. We also recommend that executives pay attention to the supplier’s moral value and construct a method to gain more control over the company’s core intangible assets.
The final recommendation requires researchers and practitioners’ cooperation. Lacity et al. [35] concerned about an undereducated outsourcing advisor can affect the expensive decision-making and can have a long-term influence for the companies. Meanwhile, Davenport and Ronanki [59] disclosed that some executives were unfamiliar with the service automation technology and its mechanism. In addition, Asatiani et al. [36] proposed that outsourcing is a complex and dynamic business strategy. With all these difficulties, we suggest that researchers and practitioners should team up together. Researchers help the practitioners to understand the outsourcing strategy and its related area professionally. Meanwhile, practitioners help researchers provide the research data and information to help academia understand the outsourcing topic better.
In this chapter, we briefly introduced the historical background of outsourcing, clarified the definition of outsourcing, discussed the motivation and risks of outsourcing, introduced the tools of risk management assessment. We also discussed the trends in outsourcing, focusing on the impact of cloud computing and service automation technology. Lastly, the chapter ends with recommendations for future researchers and practitioners in the outsourcing industry.
Parasitic plants are among the most problematic pests of agricultural crops worldwide. About 4000 parasitic plants exploit another plant vascular system to fulfill their nutrient requirements. The majority, about 90% of these species are hemiparasites retaining photosynthetic capacity while the rest, 390 species are holoparasites with obligate dependence on the host to obtain all their nutrients [1, 2]. They are extremely morphologically diverse and range from diminutive herbaceous plants to large trees, as well as highly reduced parasites that grow embedded in their host and lack leaves and roots. Parasitic plants can be divided according to whether they are photosynthetically active (hemiparasites) or lack of photosynthetic activity, and whether they are completely attached to a host for carbon (holoparasites), whether they are optional or obligate parasites, and whether they are attached to the roots or stem of the host. In natural ecosystems, parasitic plants form a component of the plant community and contribute to the overall community balance of parasitism. Conversely, when parasitic plants are established in low biodiverse agroecosystems, their persistence causes enormous yield losses and renders agricultural land inoperable. It has been determined that many features from seed germination to haustorium formation, from feeding patterns to host selection are based on the relationships between the host and the parasite [3].
Parasitic plants change in host dependence of and the rate at which they can attach. Facultative hemiparasites complete their life cycle without the need for a host. Also, obligate parasites (can be hemi- or holoparasites) need host to survive and reproduce. Most of facultative parasites have a broad range of hosts. For example,
Holoparasities and hemiparasites develop haustoria. There are two types of houstria. Primary haustorium develops directly from the primary root apex. It is the only haustorium to function during the parasite’s lifetime. When only the primary haustorium is present, the parasite is considered evolutionarily more advanced. The development of primary haustorim made holoparasitism possible because holoparasites with small seeds usually require water, and nutrients from a host immediately after germination [5].
Parasitism appeared several times independently during angiosperm evolution, and the lifestyles of parasitic plants vary widely between taxa [1]. Some species are optional parasites that can survive in the absence of a host, others are necessarily parasitic and cannot develop independently. A distinction can be made between hemiparasitic herbs containing chlorophyll and can produce some of the essential nutrients through photosynthesis, and holoparasitic plants that do not contain chlorophyll and are completely dependent on host sources, but this distinction is not always clear [6, 7]. They pose a tremendous threat to the world economy because they are virtually uncontrollable at the moment [8, 9]. They belong to a variety of plant families and are attached to host roots, shoots or branches. The mistletoes like
Weed parasites, usually unique to the host, do their greatest damage before they emerge; therefore, most crop yield loss may occur before infection is diagnosed. Despite intense efforts in the twentieth century, effective ways to selectively control various parasitic weed species are still scary or absent. While all agricultural weeds compete with crops for the field to obtain water, nutrients and light, parasitic weeds are also particularly harmful as they extract valuable water and nutrients directly from the host plant. To extract nutrients from host plants, parasitic weeds have developed a unique multicellular structure called the haustorium that invades the host, connects with the host vascular system and draws the water and nutrients it needs [10, 11]. A successful haustorial connection to the host causes permanent damage to a large part of the crop’s life cycle, lowering the harvested yield, lowering the crop value, and contaminating it with parasitic seeds. Parasitic weed infection strongly reduces crop harvest by disrupting crop orchestration of resource allocation by altering dry matter partitioning between crop organs that prioritize those adjacent to the [12].
Mistletoe (
a) Entry of triple suckers from
The way mistletoe spreads are quite interesting, with all leaves, flowers monogamous and sticky, juicy and soft fruit. Thanks to its sticky structure, the seeds that stick to the beaks and feet of the birds or the birds that eat the fruits, especially the junipers, leave their feces on the trees they put on, and the seeds continue to grow by germinating on the tree they are transported. The germinated mistletoe seeds pierce the bark of the tree and reach their suckers down to the wood pipes and share the water and mineral substances of the host. Yield losses of up to 50 percent can be seen in sensitive fruits due to mistletoe Mistletoe provides its food by inserting its suckers into the trunks and branches of fruit, park and forest trees. Swelling is seen in these parts. It weakens the host tree, decreases the yield, and sometimes causes the old trees to dry. The fruits are spherical and the abundant viscin substance in the fruit flesh provides the stickiness of the fruit and the seed [16]. The stem of the plant lives dependent on the host, if it cannot find a host, it cannot survive. Seed need to attach to the host in germination the duration is known to be 3–5 weeks. By moving the jab body end counterclockwise hugs the host he reaches. Of the held body parasitic plant from the host facing surface, it dips suckers to his host and these suckers connects with its host phloem and xylem. They typically exhibiting broad host ranges, and inflict serious damage to many crops, including forage legumes (alfalfa, clover, lespedeza), potato, carrot, sugar beets, chickpea, onion, cranberry, blueberry, and citrus [17].
Seeds of
As a full parasitic weed,
a)
The witchweeds (
In tropical Africa the most damaging parasitic weeds are
a, b, c, d)
Infected mistletoe plant samples used for isolating of bacteria and fungi [
The use of nitrogen-binding legumes as trap crops has the advantage of increasing soil fertility, which can further assist in
Parasitic plants are the biggest threats to important crops and can cause crop losses until complete failure of crop productivity. Integrated pest management systems seem to be the best solution to find effective, long-lasting, widely applicable and environmentally friendly methods for parasitic weed control. Considering the life cycle of parasitic weeds, prevention of seed germination and/or host binding would be ideal targets for the successful management of parasites. Recently, some fungal metabolites are in
The authors declare no conflict of interest.
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Plus, rib cartilage can be carved into ideal septal extension and batten grafts that are required.",book:{id:"8616",slug:"contemporary-rhinoplasty",title:"Contemporary Rhinoplasty",fullTitle:"Contemporary Rhinoplasty"},signatures:"Angelo Cuzalina and Ahmed Tamim",authors:[{id:"270232",title:"Dr.",name:"Angelo",middleName:null,surname:"Cuzalina",slug:"angelo-cuzalina",fullName:"Angelo Cuzalina"},{id:"278087",title:"Dr.",name:"Ahmed",middleName:null,surname:"Tamim",slug:"ahmed-tamim",fullName:"Ahmed Tamim"}]},{id:"36339",doi:"10.5772/29345",title:"Cochlear Implant Surgery",slug:"hearing-preservation-in-cochlear-implant-surgery",totalDownloads:7006,totalCrossrefCites:2,totalDimensionsCites:2,abstract:null,book:{id:"652",slug:"cochlear-implant-research-updates",title:"Cochlear Implant Research Updates",fullTitle:"Cochlear Implant Research Updates"},signatures:"Hakan Soken, Sarah E. Mowry and Marlan R. Hansen",authors:[{id:"77409",title:"Dr.",name:"Marlan",middleName:null,surname:"Hansen",slug:"marlan-hansen",fullName:"Marlan Hansen"},{id:"86423",title:"Dr.",name:"Hakan",middleName:null,surname:"Soken",slug:"hakan-soken",fullName:"Hakan Soken"},{id:"123447",title:"Dr.",name:"Sarah E",middleName:null,surname:"Mowry",slug:"sarah-e-mowry",fullName:"Sarah E Mowry"}]}],mostDownloadedChaptersLast30Days:[{id:"66026",title:"Alar Rim Grafts",slug:"alar-rim-grafts",totalDownloads:1119,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"Alar rim grafts date back to the 1950s for the correction of alar base in cleft lip nose. Cartilage struts under the anterior half of the alae of a pinched nose tip were popularised and the cartilage of the auricular concha became the donor site of choice for nasal procedures. Recently, some surgeons pointed to its potential role in aesthetic cases and added some technical refinements. These grafts are used for open and closed rhinoplasties. They usually consist of a rod of septal or auricular cartilage that we lay as reinforcement inside a pocket along the alar margin. Indications include the following: congenital or traumatic asymmetry, dynamic alar collapse, alar flare, primary retraction or notching, secondary (surgical or traumatic) retraction and malposition of the lateral cartilages (upwards or downwards). Harvesting and implanting techniques as well as the possible drawbacks are discussed.",book:{id:"8616",slug:"contemporary-rhinoplasty",title:"Contemporary Rhinoplasty",fullTitle:"Contemporary Rhinoplasty"},signatures:"Pedro S. Arquero, Wenceslao M. Calonge, Daniel P. Espinoza and Diana Oesch",authors:[{id:"202013",title:"M.D.",name:"Wenceslao M",middleName:null,surname:"Calonge",slug:"wenceslao-m-calonge",fullName:"Wenceslao M Calonge"},{id:"286266",title:"Dr.",name:"Daniel",middleName:null,surname:"Espinoza Kauer",slug:"daniel-espinoza-kauer",fullName:"Daniel Espinoza Kauer"},{id:"286267",title:"Dr.",name:"Diana",middleName:null,surname:"Oesch Ortiz",slug:"diana-oesch-ortiz",fullName:"Diana Oesch Ortiz"},{id:"292634",title:"Dr.",name:"Pedro S.",middleName:null,surname:"Arquero",slug:"pedro-s.-arquero",fullName:"Pedro S. Arquero"}]},{id:"65017",title:"Learning Curve and Septorhinoplasty",slug:"learning-curve-and-septorhinoplasty",totalDownloads:766,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The learning curve as a concept has been considered and discussed in medical education and surgical practice. Rollin Daniel stated that rhinoplasty is the most difficult of all cosmetic operations for three reasons: (a) nasal anatomy is highly variable, (b) the procedure must correct form and function and (c) patients’ expectations. With this in mind, a study was planned on learning curve in septorhinoplasty based on a surgeon questionnaire. The aims of the study were to extract the idea of learning curve from different surgeons across experience about septorhioplasty, to calculate certain parameters of the learning curve in rhinoplasty and to prepare a roadmap for an early rhinoplasty surgeon. The conclusion derived from the study was the concept of the learning curve in rhinoplasty should not be generalised as certain factors, for example, minimum number to achieve proficiency has a wide range. It is thought that each type of rhinoplasty should be dealt with separately and learning curve calculated accordingly. A roadmap for a novice surgeon is hereby charted out.",book:{id:"8616",slug:"contemporary-rhinoplasty",title:"Contemporary Rhinoplasty",fullTitle:"Contemporary Rhinoplasty"},signatures:"Aditya Yeolekar",authors:[{id:"266750",title:"Associate Prof.",name:"Aditya",middleName:null,surname:"Yeolekar",slug:"aditya-yeolekar",fullName:"Aditya Yeolekar"}]},{id:"64668",title:"Cleft Lip and Palate Patient Rhinoplasty",slug:"cleft-lip-and-palate-patient-rhinoplasty",totalDownloads:1805,totalCrossrefCites:0,totalDimensionsCites:2,abstract:"Cleft lip and palate patients represent one of the most difficult groups of patients for septorhinoplasty. Prior surgery at younger ages resulting in severe scar tissue is a major obstacle in most cleft rhinoplasties along with substantial asymmetries especially in the unilateral cleft patient. Replacement of missing and asymmetric cartilages and even bone is a key component for rhinoplasty in the cleft patient. Use of very sturdy cartilage typically from rib is almost always required to adequately resist the fibrotic soft tissues in the noses. Plus, rib cartilage can be carved into ideal septal extension and batten grafts that are required.",book:{id:"8616",slug:"contemporary-rhinoplasty",title:"Contemporary Rhinoplasty",fullTitle:"Contemporary Rhinoplasty"},signatures:"Angelo Cuzalina and Ahmed Tamim",authors:[{id:"270232",title:"Dr.",name:"Angelo",middleName:null,surname:"Cuzalina",slug:"angelo-cuzalina",fullName:"Angelo Cuzalina"},{id:"278087",title:"Dr.",name:"Ahmed",middleName:null,surname:"Tamim",slug:"ahmed-tamim",fullName:"Ahmed Tamim"}]},{id:"64721",title:"Saddle Nose: A Systematic Approach",slug:"saddle-nose-a-systematic-approach",totalDownloads:1077,totalCrossrefCites:0,totalDimensionsCites:0,abstract:"The saddle nose deformity is always associated to cartilaginous or bone defects. It could have congenital, traumatic, infectious or iatrogenic origin. Its correction consists not only in a camouflage, but also it is important to reconstruct the missing structure. In this chapter, we will discuss about all aspect of the saddle nose and we will propose a different therapeutical approach (septum, concha or costal grafts) in relation to the severity of the defects (with a personal classification). The classification is also based on the presence or absence of the nasal septum, which is a fundamental aspect that we must take into account when approaching nasal reconstruction. We will discuss the technical aspect of the rib graft harvesting and its use to reconstruct the nasal structure.",book:{id:"8616",slug:"contemporary-rhinoplasty",title:"Contemporary Rhinoplasty",fullTitle:"Contemporary Rhinoplasty"},signatures:"Marianetti Tito Matteo",authors:[{id:"177687",title:"Dr.",name:"Tito",middleName:null,surname:"Marianetti",slug:"tito-marianetti",fullName:"Tito Marianetti"}]},{id:"36343",title:"A Review of Stimulating Strategies for Cochlear Implants",slug:"stimulating-strategies-for-cochlear-implants",totalDownloads:4475,totalCrossrefCites:1,totalDimensionsCites:0,abstract:null,book:{id:"652",slug:"cochlear-implant-research-updates",title:"Cochlear Implant Research Updates",fullTitle:"Cochlear Implant Research Updates"},signatures:"Charles T. M. Choi and Yi-Hsuan Lee",authors:[{id:"107160",title:"Prof.",name:"Charles T. M.",middleName:null,surname:"Choi",slug:"charles-t.-m.-choi",fullName:"Charles T. M. Choi"},{id:"111315",title:"Dr.",name:"Yi-Hsuan",middleName:null,surname:"Lee",slug:"yi-hsuan-lee",fullName:"Yi-Hsuan Lee"}]}],onlineFirstChaptersFilter:{topicId:"1151",limit:6,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},subscriptionForm:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[],offset:0,limit:8,total:null},allSeries:{pteSeriesList:[{id:"14",title:"Artificial Intelligence",numberOfPublishedBooks:9,numberOfPublishedChapters:90,numberOfOpenTopics:6,numberOfUpcomingTopics:0,issn:"2633-1403",doi:"10.5772/intechopen.79920",isOpenForSubmission:!0},{id:"7",title:"Biomedical Engineering",numberOfPublishedBooks:12,numberOfPublishedChapters:104,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2631-5343",doi:"10.5772/intechopen.71985",isOpenForSubmission:!0}],lsSeriesList:[{id:"11",title:"Biochemistry",numberOfPublishedBooks:32,numberOfPublishedChapters:320,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2632-0983",doi:"10.5772/intechopen.72877",isOpenForSubmission:!0},{id:"25",title:"Environmental Sciences",numberOfPublishedBooks:1,numberOfPublishedChapters:12,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2754-6713",doi:"10.5772/intechopen.100362",isOpenForSubmission:!0},{id:"10",title:"Physiology",numberOfPublishedBooks:11,numberOfPublishedChapters:141,numberOfOpenTopics:4,numberOfUpcomingTopics:0,issn:"2631-8261",doi:"10.5772/intechopen.72796",isOpenForSubmission:!0}],hsSeriesList:[{id:"3",title:"Dentistry",numberOfPublishedBooks:8,numberOfPublishedChapters:133,numberOfOpenTopics:2,numberOfUpcomingTopics:0,issn:"2631-6218",doi:"10.5772/intechopen.71199",isOpenForSubmission:!0},{id:"6",title:"Infectious Diseases",numberOfPublishedBooks:13,numberOfPublishedChapters:113,numberOfOpenTopics:3,numberOfUpcomingTopics:1,issn:"2631-6188",doi:"10.5772/intechopen.71852",isOpenForSubmission:!0},{id:"13",title:"Veterinary Medicine and Science",numberOfPublishedBooks:11,numberOfPublishedChapters:107,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2632-0517",doi:"10.5772/intechopen.73681",isOpenForSubmission:!0}],sshSeriesList:[{id:"22",title:"Business, Management and Economics",numberOfPublishedBooks:1,numberOfPublishedChapters:19,numberOfOpenTopics:3,numberOfUpcomingTopics:0,issn:"2753-894X",doi:"10.5772/intechopen.100359",isOpenForSubmission:!0},{id:"23",title:"Education and Human Development",numberOfPublishedBooks:0,numberOfPublishedChapters:5,numberOfOpenTopics:1,numberOfUpcomingTopics:1,issn:null,doi:"10.5772/intechopen.100360",isOpenForSubmission:!0},{id:"24",title:"Sustainable Development",numberOfPublishedBooks:0,numberOfPublishedChapters:17,numberOfOpenTopics:5,numberOfUpcomingTopics:0,issn:null,doi:"10.5772/intechopen.100361",isOpenForSubmission:!0}],testimonialsList:[{id:"6",text:"It is great to work with the IntechOpen to produce a worthwhile collection of research that also becomes a great educational resource and guide for future research endeavors.",author:{id:"259298",name:"Edward",surname:"Narayan",institutionString:null,profilePictureURL:"https://mts.intechopen.com/storage/users/259298/images/system/259298.jpeg",slug:"edward-narayan",institution:{id:"3",name:"University of Queensland",country:{id:null,name:"Australia"}}}},{id:"13",text:"The collaboration with and support of the technical staff of IntechOpen is fantastic. 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Much of biochemistry is devoted to enzymes, proteins that catalyze chemical reactions, enzyme structures, mechanisms of action and their roles within cells. Biochemistry also studies small signaling molecules, coenzymes, inhibitors, vitamins, and hormones, which play roles in life processes. Biochemical experimentation, besides coopting classical chemistry methods, e.g., chromatography, adopted new techniques, e.g., X-ray diffraction, electron microscopy, NMR, radioisotopes, and developed sophisticated microbial genetic tools, e.g., auxotroph mutants and their revertants, fermentation, etc. More recently, biochemistry embraced the ‘big data’ omics systems. Initial biochemical studies have been exclusively analytic: dissecting, purifying, and examining individual components of a biological system; in the apt words of Efraim Racker (1913 –1991), “Don’t waste clean thinking on dirty enzymes.” Today, however, biochemistry is becoming more agglomerative and comprehensive, setting out to integrate and describe entirely particular biological systems. The ‘big data’ metabolomics can define the complement of small molecules, e.g., in a soil or biofilm sample; proteomics can distinguish all the comprising proteins, e.g., serum; metagenomics can identify all the genes in a complex environment, e.g., the bovine rumen. 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Dr. Blumenberg’s research is focused on the epidermis, expression of keratin genes, transcription profiling, keratinocyte differentiation, inflammatory diseases and cancers, and most recently the effects of the microbiome on the skin. He has published more than 100 peer-reviewed research articles and graduated numerous Ph.D. and postdoctoral students.",institutionString:null,institution:{name:"New York University Langone Medical Center",institutionURL:null,country:{name:"United States of America"}}},editorTwo:null,editorThree:null},subseries:{paginationCount:4,paginationItems:[{id:"14",title:"Cell and Molecular Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/14.jpg",isOpenForSubmission:!0,editor:{id:"165627",title:"Dr.",name:"Rosa María",middleName:null,surname:"Martínez-Espinosa",slug:"rosa-maria-martinez-espinosa",fullName:"Rosa María Martínez-Espinosa",profilePictureURL:"https://mts.intechopen.com/storage/users/165627/images/system/165627.jpeg",biography:"Dr. Rosa María Martínez-Espinosa has been a Spanish Full Professor since 2020 (Biochemistry and Molecular Biology) and is currently Vice-President of International Relations and Cooperation development and leader of the research group 'Applied Biochemistry” (University of Alicante, Spain). Other positions she has held at the university include Vice-Dean of Master Programs, Vice-Dean of the Degree in Biology and Vice-Dean for Mobility and Enterprise and Engagement at the Faculty of Science (University of Alicante). She received her Bachelor in Biology in 1998 (University of Alicante) and her PhD in 2003 (Biochemistry, University of Alicante). She undertook post-doctoral research at the University of East Anglia (Norwich, U.K. 2004-2005; 2007-2008).\nHer multidisciplinary research focuses on investigating archaea and their potential applications in biotechnology. She has an H-index of 21. She has authored one patent and has published more than 70 indexed papers and around 60 book chapters.\nShe has contributed to more than 150 national and international meetings during the last 15 years. Her research interests include archaea metabolism, enzymes purification and characterization, gene regulation, carotenoids and bioplastics production, antioxidant\ncompounds, waste water treatments, and brines bioremediation.\nRosa María’s other roles include editorial board member for several journals related\nto biochemistry, reviewer for more than 60 journals (biochemistry, molecular biology, biotechnology, chemistry and microbiology) and president of several organizing committees in international meetings related to the N-cycle or respiratory processes.",institutionString:null,institution:{name:"University of Alicante",institutionURL:null,country:{name:"Spain"}}},editorTwo:null,editorThree:null},{id:"15",title:"Chemical Biology",coverUrl:"https://cdn.intechopen.com/series_topics/covers/15.jpg",isOpenForSubmission:!0,editor:{id:"441442",title:"Dr.",name:"Şükrü",middleName:null,surname:"Beydemir",slug:"sukru-beydemir",fullName:"Şükrü Beydemir",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y00003GsUoIQAV/Profile_Picture_1634557147521",biography:"Dr. Şükrü Beydemir obtained a BSc in Chemistry in 1995 from Yüzüncü Yıl University, MSc in Biochemistry in 1998, and PhD in Biochemistry in 2002 from Atatürk University, Turkey. He performed post-doctoral studies at Max-Planck Institute, Germany, and University of Florence, Italy in addition to making several scientific visits abroad. He currently works as a Full Professor of Biochemistry in the Faculty of Pharmacy, Anadolu University, Turkey. Dr. Beydemir has published over a hundred scientific papers spanning protein biochemistry, enzymology and medicinal chemistry, reviews, book chapters and presented several conferences to scientists worldwide. He has received numerous publication awards from various international scientific councils. He serves in the Editorial Board of several international journals. Dr. Beydemir is also Rector of Bilecik Şeyh Edebali University, Turkey.",institutionString:null,institution:{name:"Anadolu University",institutionURL:null,country:{name:"Turkey"}}},editorTwo:{id:"13652",title:"Prof.",name:"Deniz",middleName:null,surname:"Ekinci",slug:"deniz-ekinci",fullName:"Deniz Ekinci",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002aYLT1QAO/Profile_Picture_1634557223079",biography:"Dr. Deniz Ekinci obtained a BSc in Chemistry in 2004, MSc in Biochemistry in 2006, and PhD in Biochemistry in 2009 from Atatürk University, Turkey. He studied at Stetson University, USA, in 2007-2008 and at the Max Planck Institute of Molecular Cell Biology and Genetics, Germany, in 2009-2010. Dr. Ekinci currently works as a Full Professor of Biochemistry in the Faculty of Agriculture and is the Head of the Enzyme and Microbial Biotechnology Division, Ondokuz Mayıs University, Turkey. He is a member of the Turkish Biochemical Society, American Chemical Society, and German Genetics society. Dr. Ekinci published around ninety scientific papers, reviews and book chapters, and presented several conferences to scientists. He has received numerous publication awards from several scientific councils. Dr. Ekinci serves as the Editor in Chief of four international books and is involved in the Editorial Board of several international journals.",institutionString:null,institution:{name:"Ondokuz Mayıs University",institutionURL:null,country:{name:"Turkey"}}},editorThree:null},{id:"17",title:"Metabolism",coverUrl:"https://cdn.intechopen.com/series_topics/covers/17.jpg",isOpenForSubmission:!0,editor:{id:"138626",title:"Dr.",name:"Yannis",middleName:null,surname:"Karamanos",slug:"yannis-karamanos",fullName:"Yannis Karamanos",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002g6Jv2QAE/Profile_Picture_1629356660984",biography:"Yannis Karamanos, born in Greece in 1953, completed his pre-graduate studies at the Université Pierre et Marie Curie, Paris, then his Masters and Doctoral degree at the Université de Lille (1983). He was associate professor at the University of Limoges (1987) before becoming full professor of biochemistry at the Université d’Artois (1996). He worked on the structure-function relationships of glycoconjugates and his main project was the investigations on the biological roles of the de-N-glycosylation enzymes (Endo-N-acetyl-β-D-glucosaminidase and peptide-N4-(N-acetyl-β-glucosaminyl) asparagine amidase). From 2002 he contributes to the understanding of the Blood-brain barrier functioning using proteomics approaches. He has published more than 70 papers. His teaching areas are energy metabolism and regulation, integration and organ specialization and metabolic adaptation.",institutionString:null,institution:{name:"Artois University",institutionURL:null,country:{name:"France"}}},editorTwo:null,editorThree:null},{id:"18",title:"Proteomics",coverUrl:"https://cdn.intechopen.com/series_topics/covers/18.jpg",isOpenForSubmission:!0,editor:{id:"200689",title:"Prof.",name:"Paolo",middleName:null,surname:"Iadarola",slug:"paolo-iadarola",fullName:"Paolo Iadarola",profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0030O00002bSCl8QAG/Profile_Picture_1623568118342",biography:"Paolo Iadarola graduated with a degree in Chemistry from the University of Pavia (Italy) in July 1972. He then worked as an Assistant Professor at the Faculty of Science of the same University until 1984. In 1985, Prof. Iadarola became Associate Professor at the Department of Biology and Biotechnologies of the University of Pavia and retired in October 2017. Since then, he has been working as an Adjunct Professor in the same Department at the University of Pavia. His research activity during the first years was primarily focused on the purification and structural characterization of enzymes from animal and plant sources. During this period, Prof. Iadarola familiarized himself with the conventional techniques used in column chromatography, spectrophotometry, manual Edman degradation, and electrophoresis). Since 1995, he has been working on: i) the determination in biological fluids (serum, urine, bronchoalveolar lavage, sputum) of proteolytic activities involved in the degradation processes of connective tissue matrix, and ii) on the identification of biological markers of lung diseases. In this context, he has developed and validated new methodologies (e.g., Capillary Electrophoresis coupled to Laser-Induced Fluorescence, CE-LIF) whose application enabled him to determine both the amounts of biochemical markers (Desmosines) in urine/serum of patients affected by Chronic Obstructive Pulmonary Disease (COPD) and the activity of proteolytic enzymes (Human Neutrophil Elastase, Cathepsin G, Pseudomonas aeruginosa elastase) in sputa of these patients. More recently, Prof. Iadarola was involved in developing techniques such as two-dimensional electrophoresis coupled to liquid chromatography/mass spectrometry (2DE-LC/MS) for the proteomic analysis of biological fluids aimed at the identification of potential biomarkers of different lung diseases. He is the author of about 150 publications (According to Scopus: H-Index: 23; Total citations: 1568- According to WOS: H-Index: 20; Total Citations: 1296) of peer-reviewed international journals. 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She gained considerable experience in developing and validating new methodologies whose applications allowed her to determine both the amount of biomarkers (Desmosine and Isodesmosine) in the urine of patients affected by COPD, and the activity of proteolytic enzymes (HNE, Cathepsin G, Pseudomonas aeruginosa elastase) in the sputa of these patients. Simona Viglio was also involved in research dealing with the supplementation of amino acids in patients with brain injury and chronic heart failure. She is presently engaged in the development of 2-DE and LC-MS techniques for the study of proteomics in biological fluids. The aim of this research is the identification of potential biomarkers of lung diseases. She is an author of about 90 publications (According to Scopus: H-Index: 23; According to WOS: H-Index: 20) on peer-reviewed journals, a member of the “Società Italiana di Biochimica e Biologia Molecolare,“ and a Consultant Reviewer for International Journal of Molecular Science, Journal of Chromatography A, COPD, Plos ONE and Nutritional Neuroscience.",institutionString:null,institution:{name:"University of Pavia",institutionURL:null,country:{name:"Italy"}}},editorThree:null}]},overviewPageOFChapters:{paginationCount:38,paginationItems:[{id:"82531",title:"Abnormal Iron Metabolism and Its Effect on Dentistry",doi:"10.5772/intechopen.104502",signatures:"Chinmayee Dahihandekar and Sweta Kale Pisulkar",slug:"abnormal-iron-metabolism-and-its-effect-on-dentistry",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Iron Metabolism - Iron a Double‐Edged Sword",coverURL:"https://cdn.intechopen.com/books/images_new/10842.jpg",subseries:{id:"17",title:"Metabolism"}}},{id:"82291",title:"The Role of Oxidative Stress in the Onset and Development of Age-Related Macular Degeneration",doi:"10.5772/intechopen.105599",signatures:"Emina Čolak, Lepša Žorić, Miloš Mirković, Jana Mirković, Ilija Dragojević, Dijana Mirić, Bojana Kisić and Ljubinka Nikolić",slug:"the-role-of-oxidative-stress-in-the-onset-and-development-of-age-related-macular-degeneration",totalDownloads:1,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Importance of Oxidative Stress and Antioxidant System in Health and Disease",coverURL:"https://cdn.intechopen.com/books/images_new/11671.jpg",subseries:{id:"15",title:"Chemical Biology"}}},{id:"82195",title:"Endoplasmic Reticulum: A Hub in Lipid Homeostasis",doi:"10.5772/intechopen.105450",signatures:"Raúl Ventura and María Isabel Hernández-Alvarez",slug:"endoplasmic-reticulum-a-hub-in-lipid-homeostasis",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Updates on Endoplasmic Reticulum",coverURL:"https://cdn.intechopen.com/books/images_new/11674.jpg",subseries:{id:"14",title:"Cell and Molecular Biology"}}},{id:"82409",title:"Purinergic Signaling in Covid-19 Disease",doi:"10.5772/intechopen.105008",signatures:"Hailian Shen",slug:"purinergic-signaling-in-covid-19-disease",totalDownloads:6,totalCrossrefCites:0,totalDimensionsCites:0,authors:null,book:{title:"Purinergic System",coverURL:"https://cdn.intechopen.com/books/images_new/10801.jpg",subseries:{id:"17",title:"Metabolism"}}}]},overviewPagePublishedBooks:{paginationCount:32,paginationItems:[{type:"book",id:"7006",title:"Biochemistry and Health Benefits of Fatty Acids",subtitle:null,coverURL:"https://cdn.intechopen.com/books/images_new/7006.jpg",slug:"biochemistry-and-health-benefits-of-fatty-acids",publishedDate:"December 19th 2018",editedByType:"Edited by",bookSignature:"Viduranga Waisundara",hash:"c93a00abd68b5eba67e5e719f67fd20b",volumeInSeries:1,fullTitle:"Biochemistry and Health Benefits of Fatty Acids",editors:[{id:"194281",title:"Dr.",name:"Viduranga Y.",middleName:null,surname:"Waisundara",slug:"viduranga-y.-waisundara",fullName:"Viduranga Y. 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She is now a lecturer at the University of Witwatersrand, South Africa, and a principal researcher at the Health Economics and Epidemiology Research Office (HE2RO), South Africa. Dr. Moolla holds a Ph.D. in Psychology with her research being focused on mental health and resilience. In her professional work capacity, her research has further expanded into the fields of early childhood development, mental health, the HIV and TB care cascades, as well as COVID. She is also a UNESCO-trained International Bioethics Facilitator.",institutionString:"University of the Witwatersrand",institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419588",title:"Ph.D.",name:"Sergio",middleName:"Alexandre",surname:"Gehrke",slug:"sergio-gehrke",fullName:"Sergio Gehrke",position:null,profilePictureURL:"https://s3.us-east-1.amazonaws.com/intech-files/0033Y000038WgMKQA0/Profile_Picture_2022-06-02T11:44:20.jpg",biography:"Dr. Sergio Alexandre Gehrke is a doctorate holder in two fields. The first is a Ph.D. in Cellular and Molecular Biology from the Pontificia Catholic University, Porto Alegre, Brazil, in 2010 and the other is an International Ph.D. in Bioengineering from the Universidad Miguel Hernandez, Elche/Alicante, Spain, obtained in 2020. In 2018, he completed a postdoctoral fellowship in Materials Engineering in the NUCLEMAT of the Pontificia Catholic University, Porto Alegre, Brazil. He is currently the Director of the Postgraduate Program in Implantology of the Bioface/UCAM/PgO (Montevideo, Uruguay), Director of the Cathedra of Biotechnology of the Catholic University of Murcia (Murcia, Spain), an Extraordinary Full Professor of the Catholic University of Murcia (Murcia, Spain) as well as the Director of the private center of research Biotecnos – Technology and Science (Montevideo, Uruguay). Applied biomaterials, cellular and molecular biology, and dental implants are among his research interests. He has published several original papers in renowned journals. In addition, he is also a Collaborating Professor in several Postgraduate programs at different universities all over the world.",institutionString:null,institution:{name:"Universidad Católica San Antonio de Murcia",country:{name:"Spain"}}},{id:"342152",title:"Dr.",name:"Santo",middleName:null,surname:"Grace Umesh",slug:"santo-grace-umesh",fullName:"Santo Grace Umesh",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/342152/images/16311_n.jpg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"333647",title:"Dr.",name:"Shreya",middleName:null,surname:"Kishore",slug:"shreya-kishore",fullName:"Shreya Kishore",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/333647/images/14701_n.jpg",biography:"Dr. Shreya Kishore completed her Bachelor in Dental Surgery in Chettinad Dental College and Research Institute, Chennai, and her Master of Dental Surgery (Orthodontics) in Saveetha Dental College, Chennai. She is also Invisalign certified. She’s working as a Senior Lecturer in the Department of Orthodontics, SRM Dental College since November 2019. She is actively involved in teaching orthodontics to the undergraduates and the postgraduates. Her clinical research topics include new orthodontic brackets, fixed appliances and TADs. She’s published 4 articles in well renowned indexed journals and has a published patency of her own. Her private practice is currently limited to orthodontics and works as a consultant in various clinics.",institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"323731",title:"Prof.",name:"Deepak M.",middleName:"Macchindra",surname:"Vikhe",slug:"deepak-m.-vikhe",fullName:"Deepak M. Vikhe",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/323731/images/13613_n.jpg",biography:"Dr Deepak M.Vikhe .\n\n\t\n\tDr Deepak M.Vikhe , completed his Masters & PhD in Prosthodontics from Rural Dental College, Loni securing third rank in the Pravara Institute of Medical Sciences Deemed University. He was awarded Dr.G.C.DAS Memorial Award for Research on Implants at 39th IPS conference Dubai (U A E).He has two patents under his name. He has received Dr.Saraswati medal award for best research for implant study in 2017.He has received Fully funded scholarship to Spain ,university of Santiago de Compostela. He has completed fellowship in Implantlogy from Noble Biocare. \nHe has attended various conferences and CDE programmes and has national publications to his credit. His field of interest is in Implant supported prosthesis. Presently he is working as a associate professor in the Dept of Prosthodontics, Rural Dental College, Loni and maintains a successful private practice specialising in Implantology at Rahata.\n\nEmail: drdeepak_mvikhe@yahoo.com..................",institutionString:null,institution:{name:"Pravara Institute of Medical Sciences",country:{name:"India"}}},{id:"204110",title:"Dr.",name:"Ahmed A.",middleName:null,surname:"Madfa",slug:"ahmed-a.-madfa",fullName:"Ahmed A. Madfa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204110/images/system/204110.jpg",biography:"Dr. Madfa is currently Associate Professor of Endodontics at Thamar University and a visiting lecturer at Sana'a University and University of Sciences and Technology. He has more than 6 years of experience in teaching. His research interests include root canal morphology, functionally graded concept, dental biomaterials, epidemiology and dental education, biomimetic restoration, finite element analysis and endodontic regeneration. Dr. Madfa has numerous international publications, full articles, two patents, a book and a book chapter. Furthermore, he won 14 international scientific awards. Furthermore, he is involved in many academic activities ranging from editorial board member, reviewer for many international journals and postgraduate students' supervisor. Besides, I deliver many courses and training workshops at various scientific events. Dr. Madfa also regularly attends international conferences and holds administrative positions (Deputy Dean of the Faculty for Students’ & Academic Affairs and Deputy Head of Research Unit).",institutionString:"Thamar University",institution:null},{id:"210472",title:"Dr.",name:"Nermin",middleName:"Mohammed Ahmed",surname:"Yussif",slug:"nermin-yussif",fullName:"Nermin Yussif",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/210472/images/system/210472.jpg",biography:"Dr. Nermin Mohammed Ahmed Yussif is working at the Faculty of dentistry, University for October university for modern sciences and arts (MSA). Her areas of expertise include: periodontology, dental laserology, oral implantology, periodontal plastic surgeries, oral mesotherapy, nutrition, dental pharmacology. She is an editor and reviewer in numerous international journals.",institutionString:"MSA University",institution:null},{id:"204606",title:"Dr.",name:"Serdar",middleName:null,surname:"Gözler",slug:"serdar-gozler",fullName:"Serdar Gözler",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/204606/images/system/204606.jpeg",biography:"Dr. Serdar Gözler has completed his undergraduate studies at the Marmara University Faculty of Dentistry in 1978, followed by an assistantship in the Prosthesis Department of Dicle University Faculty of Dentistry. Starting his PhD work on non-resilient overdentures with Assoc. Prof. Hüsnü Yavuzyılmaz, he continued his studies with Prof. Dr. Gürbüz Öztürk of Istanbul University Faculty of Dentistry Department of Prosthodontics, this time on Gnatology. He attended training programs on occlusion, neurology, neurophysiology, EMG, radiology and biostatistics. In 1982, he presented his PhD thesis \\Gerber and Lauritzen Occlusion Analysis Techniques: Diagnosis Values,\\ at Istanbul University School of Dentistry, Department of Prosthodontics. As he was also working with Prof. Senih Çalıkkocaoğlu on The Physiology of Chewing at the same time, Gözler has written a chapter in Çalıkkocaoğlu\\'s book \\Complete Prostheses\\ entitled \\The Place of Neuromuscular Mechanism in Prosthetic Dentistry.\\ The book was published five times since by the Istanbul University Publications. Having presented in various conferences about occlusion analysis until 1998, Dr. Gözler has also decided to use the T-Scan II occlusion analysis method. Having been personally trained by Dr. Robert Kerstein on this method, Dr. Gözler has been lecturing on the T-Scan Occlusion Analysis Method in conferences both in Turkey and abroad. Dr. Gözler has various articles and presentations on Digital Occlusion Analysis methods. He is now Head of the TMD Clinic at Prosthodontic Department of Faculty of Dentistry , Istanbul Aydın University , Turkey.",institutionString:"Istanbul Aydin University",institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"240870",title:"Ph.D.",name:"Alaa Eddin Omar",middleName:null,surname:"Al Ostwani",slug:"alaa-eddin-omar-al-ostwani",fullName:"Alaa Eddin Omar Al Ostwani",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/240870/images/system/240870.jpeg",biography:"Dr. Al Ostwani Alaa Eddin Omar received his Master in dentistry from Damascus University in 2010, and his Ph.D. in Pediatric Dentistry from Damascus University in 2014. Dr. Al Ostwani is an assistant professor and faculty member at IUST University since 2014. \nDuring his academic experience, he has received several awards including the scientific research award from the Union of Arab Universities, the Syrian gold medal and the international gold medal for invention and creativity. Dr. Al Ostwani is a Member of the International Association of Dental Traumatology and the Syrian Society for Research and Preventive Dentistry since 2017. He is also a Member of the Reviewer Board of International Journal of Dental Medicine (IJDM), and the Indian Journal of Conservative and Endodontics since 2016.",institutionString:"International University for Science and Technology.",institution:{name:"Islamic University of Science and Technology",country:{name:"India"}}},{id:"42847",title:"Dr.",name:"Belma",middleName:null,surname:"Işik Aslan",slug:"belma-isik-aslan",fullName:"Belma Işik Aslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/42847/images/system/42847.jpg",biography:"Dr. Belma IşIk Aslan was born in 1976 in Ankara-TURKEY. After graduating from TED Ankara College in 1994, she attended to Gazi University, Faculty of Dentistry in Ankara. She completed her PhD in orthodontic education at Gazi University between 1999-2005. Dr. Işık Aslan stayed at the Providence Hospital Craniofacial Institude and Reconstructive Surgery in Michigan, USA for three months as an observer. She worked as a specialist doctor at Gazi University, Dentistry Faculty, Department of Orthodontics between 2005-2014. She was appointed as associate professor in January, 2014 and as professor in 2021. Dr. Işık Aslan still works as an instructor at the same faculty. She has published a total of 35 articles, 10 book chapters, 39 conference proceedings both internationally and nationally. Also she was the academic editor of the international book 'Current Advances in Orthodontics'. She is a member of the Turkish Orthodontic Society and Turkish Cleft Lip and Palate Society. She is married and has 2 children. Her knowledge of English is at an advanced level.",institutionString:"Gazi University Dentistry Faculty Department of Orthodontics",institution:null},{id:"178412",title:"Associate Prof.",name:"Guhan",middleName:null,surname:"Dergin",slug:"guhan-dergin",fullName:"Guhan Dergin",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178412/images/6954_n.jpg",biography:"Assoc. Prof. Dr. Gühan Dergin was born in 1973 in Izmit. He graduated from Marmara University Faculty of Dentistry in 1999. He completed his specialty of OMFS surgery in Marmara University Faculty of Dentistry and obtained his PhD degree in 2006. In 2005, he was invited as a visiting doctor in the Oral and Maxillofacial Surgery Department of the University of North Carolina, USA, where he went on a scholarship. Dr. Dergin still continues his academic career as an associate professor in Marmara University Faculty of Dentistry. He has many articles in international and national scientific journals and chapters in books.",institutionString:null,institution:{name:"Marmara University",country:{name:"Turkey"}}},{id:"178414",title:"Prof.",name:"Yusuf",middleName:null,surname:"Emes",slug:"yusuf-emes",fullName:"Yusuf Emes",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/178414/images/6953_n.jpg",biography:"Born in Istanbul in 1974, Dr. Emes graduated from Istanbul University Faculty of Dentistry in 1997 and completed his PhD degree in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery in 2005. He has papers published in international and national scientific journals, including research articles on implantology, oroantral fistulas, odontogenic cysts, and temporomandibular disorders. Dr. Emes is currently working as a full-time academic staff in Istanbul University faculty of Dentistry Department of Oral and Maxillofacial Surgery.",institutionString:null,institution:{name:"Istanbul University",country:{name:"Turkey"}}},{id:"192229",title:"Ph.D.",name:"Ana Luiza",middleName:null,surname:"De Carvalho Felippini",slug:"ana-luiza-de-carvalho-felippini",fullName:"Ana Luiza De Carvalho Felippini",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/192229/images/system/192229.jpg",biography:null,institutionString:"University of São Paulo",institution:{name:"University of Sao Paulo",country:{name:"Brazil"}}},{id:"256851",title:"Prof.",name:"Ayşe",middleName:null,surname:"Gülşen",slug:"ayse-gulsen",fullName:"Ayşe Gülşen",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256851/images/9696_n.jpg",biography:"Dr. Ayşe Gülşen graduated in 1990 from Faculty of Dentistry, University of Ankara and did a postgraduate program at University of Gazi. \nShe worked as an observer and research assistant in Craniofacial Surgery Departments in New York, Providence Hospital in Michigan and Chang Gung Memorial Hospital in Taiwan. \nShe works as Craniofacial Orthodontist in Department of Aesthetic, Plastic and Reconstructive Surgery, Faculty of Medicine, University of Gazi, Ankara Turkey since 2004.",institutionString:"Univeristy of Gazi",institution:null},{id:"255366",title:"Prof.",name:"Tosun",middleName:null,surname:"Tosun",slug:"tosun-tosun",fullName:"Tosun Tosun",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/255366/images/7347_n.jpg",biography:"Graduated at the Faculty of Dentistry, University of Istanbul, Turkey in 1989;\nVisitor Assistant at the University of Padua, Italy and Branemark Osseointegration Center of Treviso, Italy between 1993-94;\nPhD thesis on oral implantology in University of Istanbul and was awarded the academic title “Dr.med.dent.”, 1997;\nHe was awarded the academic title “Doç.Dr.” (Associated Professor) in 2003;\nProficiency in Botulinum Toxin Applications, Reading-UK in 2009;\nMastership, RWTH Certificate in Laser Therapy in Dentistry, AALZ-Aachen University, Germany 2009-11;\nMaster of Science (MSc) in Laser Dentistry, University of Genoa, Italy 2013-14.\n\nDr.Tosun worked as Research Assistant in the Department of Oral Implantology, Faculty of Dentistry, University of Istanbul between 1990-2002. \nHe worked part-time as Consultant surgeon in Harvard Medical International Hospitals and John Hopkins Medicine, Istanbul between years 2007-09.\u2028He was contract Professor in the Department of Surgical and Diagnostic Sciences (DI.S.C.), Medical School, University of Genova, Italy between years 2011-16. \nSince 2015 he is visiting Professor at Medical School, University of Plovdiv, Bulgaria. \nCurrently he is Associated Prof.Dr. at the Dental School, Oral Surgery Dept., Istanbul Aydin University and since 2003 he works in his own private clinic in Istanbul, Turkey.\u2028\nDr.Tosun is reviewer in journal ‘Laser in Medical Sciences’, reviewer in journal ‘Folia Medica\\', a Fellow of the International Team for Implantology, Clinical Lecturer of DGZI German Association of Oral Implantology, Expert Lecturer of Laser&Health Academy, Country Representative of World Federation for Laser Dentistry, member of European Federation of Periodontology, member of Academy of Laser Dentistry. Dr.Tosun presents papers in international and national congresses and has scientific publications in international and national journals. He speaks english, spanish, italian and french.",institutionString:null,institution:{name:"Istanbul Aydın University",country:{name:"Turkey"}}},{id:"260116",title:"Dr.",name:"Mehmet",middleName:null,surname:"Yaltirik",slug:"mehmet-yaltirik",fullName:"Mehmet Yaltirik",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/260116/images/7413_n.jpg",biography:"Birth Date 25.09.1965\r\nBirth Place Adana- Turkey\r\nSex Male\r\nMarrial Status Bachelor\r\nDriving License Acquired\r\nMother Tongue Turkish\r\n\r\nAddress:\r\nWork:University of Istanbul,Faculty of Dentistry, Department of Oral Surgery and Oral Medicine 34093 Capa,Istanbul- TURKIYE",institutionString:null,institution:{name:"Istanbul University",country:{name:"Turkey"}}},{id:"171887",title:"Prof.",name:"Zühre",middleName:null,surname:"Akarslan",slug:"zuhre-akarslan",fullName:"Zühre Akarslan",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/171887/images/system/171887.jpg",biography:"Zühre Akarslan was born in 1977 in Cyprus. She graduated from Gazi University Faculty of Dentistry, Ankara, Turkey in 2000. \r\nLater she received her Ph.D. degree from the Oral Diagnosis and Radiology Department; which was recently renamed as Oral and Dentomaxillofacial Radiology, from the same university. \r\nShe is working as a full-time Associate Professor and is a lecturer and an academic researcher. \r\nHer expertise areas are dental caries, cancer, dental fear and anxiety, gag reflex in dentistry, oral medicine, and dentomaxillofacial radiology.",institutionString:"Gazi University",institution:{name:"Gazi University",country:{name:"Turkey"}}},{id:"256417",title:"Associate Prof.",name:"Sanaz",middleName:null,surname:"Sadry",slug:"sanaz-sadry",fullName:"Sanaz Sadry",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/256417/images/8106_n.jpg",biography:null,institutionString:null,institution:null},{id:"272237",title:"Dr.",name:"Pinar",middleName:"Kiymet",surname:"Karataban",slug:"pinar-karataban",fullName:"Pinar Karataban",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/272237/images/8911_n.png",biography:"Assist.Prof.Dr.Pınar Kıymet Karataban, DDS PhD \n\nDr.Pınar Kıymet Karataban was born in Istanbul in 1975. After her graduation from Marmara University Faculty of Dentistry in 1998 she started her PhD in Paediatric Dentistry focused on children with special needs; mainly children with Cerebral Palsy. She finished her pHD thesis entitled \\'Investigation of occlusion via cast analysis and evaluation of dental caries prevalance, periodontal status and muscle dysfunctions in children with cerebral palsy” in 2008. She got her Assist. Proffessor degree in Istanbul Aydın University Paediatric Dentistry Department in 2015-2018. ın 2019 she started her new career in Bahcesehir University, Istanbul as Head of Department of Pediatric Dentistry. In 2020 she was accepted to BAU International University, Batumi as Professor of Pediatric Dentistry. She’s a lecturer in the same university meanwhile working part-time in private practice in Ege Dental Studio (https://www.egedisklinigi.com/) a multidisciplinary dental clinic in Istanbul. Her main interests are paleodontology, ancient and contemporary dentistry, oral microbiology, cerebral palsy and special care dentistry. She has national and international publications, scientific reports and is a member of IAPO (International Association for Paleodontology), IADH (International Association of Disability and Oral Health) and EAPD (European Association of Pediatric Dentistry).",institutionString:null,institution:null},{id:"202198",title:"Dr.",name:"Buket",middleName:null,surname:"Aybar",slug:"buket-aybar",fullName:"Buket Aybar",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/202198/images/6955_n.jpg",biography:"Buket Aybar, DDS, PhD, was born in 1971. She graduated from Istanbul University, Faculty of Dentistry, in 1992 and completed her PhD degree on Oral and Maxillofacial Surgery in Istanbul University in 1997.\nDr. Aybar is currently a full-time professor in Istanbul University, Faculty of Dentistry Department of Oral and Maxillofacial Surgery. She has teaching responsibilities in graduate and postgraduate programs. Her clinical practice includes mainly dentoalveolar surgery.\nHer topics of interest are biomaterials science and cell culture studies. She has many articles in international and national scientific journals and chapters in books; she also has participated in several scientific projects supported by Istanbul University Research fund.",institutionString:null,institution:null},{id:"172009",title:"Dr.",name:"Fatma Deniz",middleName:null,surname:"Uzuner",slug:"fatma-deniz-uzuner",fullName:"Fatma Deniz Uzuner",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/172009/images/7122_n.jpg",biography:"Dr. Deniz Uzuner was born in 1969 in Kocaeli-TURKEY. After graduating from TED Ankara College in 1986, she attended the Hacettepe University, Faculty of Dentistry in Ankara. \nIn 1993 she attended the Gazi University, Faculty of Dentistry, Department of Orthodontics for her PhD education. After finishing the PhD education, she worked as orthodontist in Ankara Dental Hospital under the Turkish Government, Ministry of Health and in a special Orthodontic Clinic till 2011. Between 2011 and 2016, Dr. Deniz Uzuner worked as a specialist in the Department of Orthodontics, Faculty of Dentistry, Gazi University in Ankara/Turkey. In 2016, she was appointed associate professor. Dr. Deniz Uzuner has authored 23 Journal Papers, 3 Book Chapters and has had 39 oral/poster presentations. She is a member of the Turkish Orthodontic Society. Her knowledge of English is at an advanced level.",institutionString:null,institution:null},{id:"332914",title:"Dr.",name:"Muhammad Saad",middleName:null,surname:"Shaikh",slug:"muhammad-saad-shaikh",fullName:"Muhammad Saad Shaikh",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Jinnah Sindh Medical University",country:{name:"Pakistan"}}},{id:"315775",title:"Dr.",name:"Feng",middleName:null,surname:"Luo",slug:"feng-luo",fullName:"Feng Luo",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Sichuan University",country:{name:"China"}}},{id:"423519",title:"Dr.",name:"Sizakele",middleName:null,surname:"Ngwenya",slug:"sizakele-ngwenya",fullName:"Sizakele Ngwenya",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of the Witwatersrand",country:{name:"South Africa"}}},{id:"419270",title:"Dr.",name:"Ann",middleName:null,surname:"Chianchitlert",slug:"ann-chianchitlert",fullName:"Ann Chianchitlert",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419271",title:"Dr.",name:"Diane",middleName:null,surname:"Selvido",slug:"diane-selvido",fullName:"Diane Selvido",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"419272",title:"Dr.",name:"Irin",middleName:null,surname:"Sirisoontorn",slug:"irin-sirisoontorn",fullName:"Irin Sirisoontorn",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Walailak University",country:{name:"Thailand"}}},{id:"355660",title:"Dr.",name:"Anitha",middleName:null,surname:"Mani",slug:"anitha-mani",fullName:"Anitha Mani",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"355612",title:"Dr.",name:"Janani",middleName:null,surname:"Karthikeyan",slug:"janani-karthikeyan",fullName:"Janani Karthikeyan",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}},{id:"334400",title:"Dr.",name:"Suvetha",middleName:null,surname:"Siva",slug:"suvetha-siva",fullName:"Suvetha Siva",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"SRM Dental College",country:{name:"India"}}}]}},subseries:{item:{id:"93",type:"subseries",title:"Inclusivity and Social Equity",keywords:"Social contract, SDG, Human rights, Inclusiveness, Equity, Democracy, Personal learning, Collaboration, Glocalization",scope:"